ELASPIC home << Job #oncokb << O60674.D544H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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O60674.D544H

Detailed results for job #oncokb produced by ELASPIC
O60674, Tyrosine-protein kinase JAK2:
D544H
1
1132
Pkinase_Tyr
Pkinase_Tyr

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O60674.D544H

Completed successfully

Protein, domain: O60674 Pkinase_Tyr

Type: Core (stability)

PDB template used: 4fvr_A

Seq identity: 0.989 Model score: -1.212

ELASPIC ΔΔG: 0.565

ELASPIC2 (EL2) score: 2.134

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.