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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

O43502.R258H

Detailed results for job #oncokb produced by ELASPIC

O43502, DNA repair protein RAD51 homolog 3:
R258H
1
376
RAD51 isoform 2, Isoform 2 of DNA repair protein RAD51 homolog 1:
1
242
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O43502.R258H

Completed successfully

Protein, domain: O43502 Rad51

Interacting with: RAD51 isoform 2 Rad51

PDB templates used: 1szp_F, 1szp_E

Seq identity: 0.308, 0.575 Model score: 1.213

ELASPIC ΔΔG: 1.732

ELASPIC2 (EL2) score: 1.337

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation


If you use these results, please cite the papers on this page.