ELASPIC home << Job #oncokb << O43502.D159N
x
Choose which mutations you want to be shown in the result table below.
Reset to show everything.
x
Status of calculations
: Completed with success
: Mutation not in domain
: Running
: In task queue
: Error
When calculations are done, you can click on each mutation to see their detailed results.
x
Try again
can be rerun by clicking the button:
RERUN
For more information about the error, contact us.
x
ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
x
ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

O43502.D159N

Detailed results for job #oncokb produced by ELASPIC
O43502, DNA repair protein RAD51 homolog 3:
D159N
1
376
Rad51
RA51B isoform 1, Isoform 2 of DNA repair protein RAD51 homolog 2:
1
350
Rad51
Select affected interaction:
Set mode: JAVA | HTML5
Set quality: Best | Normal | Worst
Model: Wild-type | Mutant | Both
Center camera: Protein | Mutation
Clone in larger window
Cartoon: On | Off | Translucent
Sticks: On | Off | Within Å:
Labels: On | Off | Only sticks

O43502.D159N

Completed successfully

Protein, domain: O43502 Rad51

Interacting with: RA51B isoform 1 Rad51

PDB templates used: 2zud_A, 2zud_B

Seq identity: 0.311, 0.294 Model score: 0.902

ELASPIC ΔΔG: 0.110

ELASPIC2 (EL2) score: 0.522

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.