ELASPIC home << Job #oncokb << O14980.C528S
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

O14980.C528S

Detailed results for job #oncokb produced by ELASPIC
O14980, Exportin-1:
C528S
1
1071
IBN_N+Xpo1+CRM1_C
SNUPN, Snurportin-1:
1
360
Snurportin1
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Model: Wild-type | Mutant | Both
Protein: O14980 | SNUPN | Cofactors | All
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O14980.C528S

Completed successfully

Protein, domain: O14980 IBN_N+Xpo1+CRM1_C

Interacting with: SNUPN Snurportin1

PDB templates used: 3nc0_D, 3nc0_E

Seq identity: 0.978, 0.808 Model score: -0.651

ELASPIC ΔΔG: 1.129

ELASPIC2 (EL2) score: 1.162

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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