ELASPIC home << Job #oncokb << O14965.K162D
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

O14965.K162D

Detailed results for job #oncokb produced by ELASPIC
O14965, Aurora kinase A:
K162D
1
403
Pkinase
MAPK6, Mitogen-activated protein kinase 6:
1
721
Pkinase
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O14965.K162D

Completed successfully

Protein, domain: O14965 Pkinase

Interacting with: MAPK6 Pkinase

PDB templates used: 2i6l_B, 2i6l_A

Seq identity: 0.241, 0.942 Model score: 0.233

ELASPIC ΔΔG: 2.455

ELASPIC2 (EL2) score: 2.159

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.