ELASPIC home << Job #oncokb << O14746.P704S
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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O14746.P704S

Detailed results for job #oncokb produced by ELASPIC
O14746, Telomerase reverse transcriptase:
P704S
1
1132
Telomerase_RBD
RVT_1

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O14746.P704S

Completed successfully

Protein, domain: O14746 RVT_1

Type: Core (stability)

PDB template used: 3kyl_A

Seq identity: 0.333 Model score: 3.248

ELASPIC ΔΔG: 0.027

ELASPIC2 (EL2) score: -0.430

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.