ELASPIC home << Job #oncokb << O14522.V995M
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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O14522.V995M

Detailed results for job #oncokb produced by ELASPIC
O14522, Receptor-type tyrosine-protein phosphatase T:
V995M
1
1441
MAM
fn3
fn3
Y_phosphatase
Y_phosphatase
Q96IA0, PTPRN protein (Fragment):
1
811
Recepto..
Y_phosphatase
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Protein: O14522 | Q96IA0 | Cofactors | All
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O14522.V995M

Completed successfully

Protein, domain: O14522 Y_phosphatase

Interacting with: Q96IA0 Y_phosphatase

PDB templates used: 3qce_A, 3qce_B

Seq identity: 0.487, 0.410 Model score: -0.507

ELASPIC ΔΔG: 0.532

ELASPIC2 (EL2) score: -0.423

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

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