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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

Results

Prediction results for job #spike-sars2-co produced by ELASPIC

All the mutations are done!

Filter your results

By protein:

By status:



By type:



By score:
Seq iden
Align score
Model
Provean
ΔΔG
EL2 score

The table below shows a summary of the results (download files).
To see detailed results, click on each completed mutation.

Job submitted: Dec. 18, 2020, 6:10 a.m.
Job completed: Dec. 18, 2020, 6:10 a.m.

Your results will be kept for 90 days from last access.

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Protein Mutation Type Template Seq iden Align score Model Provean ΔΔG
EL2
6zoy-rbd.pdbA115C Core INPUTA1.0001.000-0.483-2.2290.5581.685
6zoy-rbd.pdbA115D Core INPUTA1.0001.000-0.483-3.4471.8392.343
6zoy-rbd.pdbA115E Core INPUTA1.0001.000-0.483-2.6942.4322.012
6zoy-rbd.pdbA115F Core INPUTA1.0001.000-0.483-1.3260.2502.675
6zoy-rbd.pdbA115G Core INPUTA1.0001.000-0.483-2.6030.8491.261
6zoy-rbd.pdbA115H Core INPUTA1.0001.000-0.483-1.6770.4852.782
6zoy-rbd.pdbA115I Core INPUTA1.0001.000-0.483-2.185-0.1902.339
6zoy-rbd.pdbA115K Core INPUTA1.0001.000-0.483-2.7380.9212.607
6zoy-rbd.pdbA115L Core INPUTA1.0001.000-0.483-2.1790.0952.234
6zoy-rbd.pdbA115M Core INPUTA1.0001.000-0.483-2.052-0.0202.035
6zoy-rbd.pdbA115N Core INPUTA1.0001.000-0.483-2.6521.0732.315
6zoy-rbd.pdbA115P Core INPUTA1.0001.000-0.483-2.6401.3162.630
6zoy-rbd.pdbA115Q Core INPUTA1.0001.000-0.483-2.3910.4692.294
6zoy-rbd.pdbA115R Core INPUTA1.0001.000-0.483-2.7160.3762.799
6zoy-rbd.pdbA115S Core INPUTA1.0001.000-0.483-1.1980.301-0.177
6zoy-rbd.pdbA115T Core INPUTA1.0001.000-0.483-1.7480.6530.919
6zoy-rbd.pdbA115V Core INPUTA1.0001.000-0.483-1.747-0.1241.776
6zoy-rbd.pdbA115W Core INPUTA1.0001.000-0.483-2.6220.1412.420
6zoy-rbd.pdbA115Y Core INPUTA1.0001.000-0.4830.234-0.1862.630
6zoy-rbd.pdbA155C Core INPUTA1.0001.000-0.483-0.261-0.0510.505
6zoy-rbd.pdbA155D Core INPUTA1.0001.000-0.483-0.459-0.860-0.632
6zoy-rbd.pdbA155E Core INPUTA1.0001.000-0.483-0.315-0.549-0.598
6zoy-rbd.pdbA155F Core INPUTA1.0001.000-0.483-1.127-1.3860.586
6zoy-rbd.pdbA155G Core INPUTA1.0001.000-0.483-0.8060.318-0.675
6zoy-rbd.pdbA155H Core INPUTA1.0001.000-0.483-0.303-0.1080.315
6zoy-rbd.pdbA155I Core INPUTA1.0001.000-0.483-0.7240.1280.647
6zoy-rbd.pdbA155K Core INPUTA1.0001.000-0.483-0.146-0.382-0.462
6zoy-rbd.pdbA155L Core INPUTA1.0001.000-0.483-1.001-0.1010.369
6zoy-rbd.pdbA155M Core INPUTA1.0001.000-0.483-0.673-0.7030.236
6zoy-rbd.pdbA155N Core INPUTA1.0001.000-0.483-0.576-0.117-0.032
6zoy-rbd.pdbA155P Core INPUTA1.0001.000-0.4832.359-1.790-1.551
6zoy-rbd.pdbA155Q Core INPUTA1.0001.000-0.4830.110-0.468-0.145
6zoy-rbd.pdbA155R Core INPUTA1.0001.000-0.483-0.863-0.034-0.442
6zoy-rbd.pdbA155S Core INPUTA1.0001.000-0.483-0.295-0.066-0.299
6zoy-rbd.pdbA155T Core INPUTA1.0001.000-0.4830.215-0.1290.240
6zoy-rbd.pdbA155V Core INPUTA1.0001.000-0.483-0.115-0.1490.206
6zoy-rbd.pdbA155W Core INPUTA1.0001.000-0.483-1.436-0.4530.472
6zoy-rbd.pdbA155Y Core INPUTA1.0001.000-0.483-1.006-1.4380.175
6zoy-rbd.pdbA200C Core INPUTA1.0001.000-0.483-1.2910.1870.009
6zoy-rbd.pdbA200D Core INPUTA1.0001.000-0.483-0.711-0.181-1.573
6zoy-rbd.pdbA200E Core INPUTA1.0001.000-0.483-1.197-0.127-1.448
6zoy-rbd.pdbA200F Core INPUTA1.0001.000-0.483-2.1910.1380.043
6zoy-rbd.pdbA200G Core INPUTA1.0001.000-0.4830.410-0.336-0.867
6zoy-rbd.pdbA200H Core INPUTA1.0001.000-0.483-1.7800.358-0.556
6zoy-rbd.pdbA200I Core INPUTA1.0001.000-0.483-1.8880.3790.473
6zoy-rbd.pdbA200K Core INPUTA1.0001.000-0.483-0.882-0.080-0.900
6zoy-rbd.pdbA200L Core INPUTA1.0001.000-0.483-2.0550.2590.057
6zoy-rbd.pdbA200M Core INPUTA1.0001.000-0.483-1.678-0.0120.311
6zoy-rbd.pdbA200N Core INPUTA1.0001.000-0.483-0.887-0.169-0.916
6zoy-rbd.pdbA200P Core INPUTA1.0001.000-0.483-1.2220.018-0.546
6zoy-rbd.pdbA200Q Core INPUTA1.0001.000-0.483-1.1640.344-0.851
6zoy-rbd.pdbA200R Core INPUTA1.0001.000-0.483-1.411-0.150-0.912
6zoy-rbd.pdbA200S Core INPUTA1.0001.000-0.483-0.581-0.092-1.162
6zoy-rbd.pdbA200T Core INPUTA1.0001.000-0.483-0.8950.464-0.574
6zoy-rbd.pdbA200V Core INPUTA1.0001.000-0.483-1.3260.331-0.396
6zoy-rbd.pdbA200W Core INPUTA1.0001.000-0.483-1.1570.1960.436
6zoy-rbd.pdbA200Y Core INPUTA1.0001.000-0.483-1.7080.053-0.081
6zoy-rbd.pdbA202C Core INPUTA1.0001.000-0.483-0.9890.142-0.103
6zoy-rbd.pdbA202D Core INPUTA1.0001.000-0.4830.3740.1700.150
6zoy-rbd.pdbA202E Core INPUTA1.0001.000-0.4830.0440.3170.012
6zoy-rbd.pdbA202F Core INPUTA1.0001.000-0.483-1.8190.5660.653
6zoy-rbd.pdbA202G Core INPUTA1.0001.000-0.4830.025-0.5310.408
6zoy-rbd.pdbA202H Core INPUTA1.0001.000-0.483-0.331-0.0610.237
6zoy-rbd.pdbA202I Core INPUTA1.0001.000-0.483-1.6010.4990.800
6zoy-rbd.pdbA202K Core INPUTA1.0001.000-0.483-0.1520.386-0.207
6zoy-rbd.pdbA202L Core INPUTA1.0001.000-0.483-1.8260.8920.749
6zoy-rbd.pdbA202M Core INPUTA1.0001.000-0.483-1.1340.4190.372
6zoy-rbd.pdbA202N Core INPUTA1.0001.000-0.4830.597-0.3040.114
6zoy-rbd.pdbA202P Core INPUTA1.0001.000-0.483-0.9820.3531.082
6zoy-rbd.pdbA202Q Core INPUTA1.0001.000-0.4830.1320.1590.032
6zoy-rbd.pdbA202R Core INPUTA1.0001.000-0.483-0.3890.342-0.153
6zoy-rbd.pdbA202S Core INPUTA1.0001.000-0.4830.550-0.308-0.770
6zoy-rbd.pdbA202T Core INPUTA1.0001.000-0.483-0.1340.194-0.171
6zoy-rbd.pdbA202V Core INPUTA1.0001.000-0.483-1.3000.3740.148
6zoy-rbd.pdbA202W Core INPUTA1.0001.000-0.483-1.8970.5710.939
6zoy-rbd.pdbA202Y Core INPUTA1.0001.000-0.483-1.0940.6910.240
6zoy-rbd.pdbA24C Core INPUTA1.0001.000-0.483-2.1370.2401.659
6zoy-rbd.pdbA24D Core INPUTA1.0001.000-0.483-1.2230.2700.818
6zoy-rbd.pdbA24E Core INPUTA1.0001.000-0.483-1.3600.1831.420
6zoy-rbd.pdbA24F Core INPUTA1.0001.000-0.483-2.7750.2762.384
6zoy-rbd.pdbA24G Core INPUTA1.0001.000-0.483-0.8580.4990.261
6zoy-rbd.pdbA24H Core INPUTA1.0001.000-0.483-1.9880.3341.549
6zoy-rbd.pdbA24I Core INPUTA1.0001.000-0.483-2.2920.8322.381
6zoy-rbd.pdbA24K Core INPUTA1.0001.000-0.483-1.6930.4381.781
6zoy-rbd.pdbA24L Core INPUTA1.0001.000-0.483-2.3070.1722.134
6zoy-rbd.pdbA24M Core INPUTA1.0001.000-0.483-2.1280.0601.806
6zoy-rbd.pdbA24N Core INPUTA1.0001.000-0.483-1.5470.2621.009
6zoy-rbd.pdbA24P Core INPUTA1.0001.000-0.483-0.3370.3490.389
6zoy-rbd.pdbA24Q Core INPUTA1.0001.000-0.483-1.3550.2501.754
6zoy-rbd.pdbA24R Core INPUTA1.0001.000-0.483-1.9350.1271.781
6zoy-rbd.pdbA24S Core INPUTA1.0001.000-0.483-0.7050.228-1.830
6zoy-rbd.pdbA24T Core INPUTA1.0001.000-0.483-1.3500.6031.048
6zoy-rbd.pdbA24V Core INPUTA1.0001.000-0.483-1.8770.8391.907
6zoy-rbd.pdbA24W Core INPUTA1.0001.000-0.483-2.6490.7252.081
6zoy-rbd.pdbA24Y Core INPUTA1.0001.000-0.483-2.3440.3001.852
6zoy-rbd.pdbA28C Core INPUTA1.0001.000-0.483-1.3300.2530.940
6zoy-rbd.pdbA28D Core INPUTA1.0001.000-0.483-0.0620.212-1.065
6zoy-rbd.pdbA28E Core INPUTA1.0001.000-0.4830.040-0.061-0.936
6zoy-rbd.pdbA28F Core INPUTA1.0001.000-0.483-1.8790.0991.213
6zoy-rbd.pdbA28G Core INPUTA1.0001.000-0.483-0.7680.537-0.342
6zoy-rbd.pdbA28H Core INPUTA1.0001.000-0.483-0.7740.3180.147
6zoy-rbd.pdbA28I Core INPUTA1.0001.000-0.483-0.5520.5170.484
6zoy-rbd.pdbA28K Core INPUTA1.0001.000-0.483-0.010-0.226-1.418
6zoy-rbd.pdbA28L Core INPUTA1.0001.000-0.483-0.7520.1540.285
6zoy-rbd.pdbA28M Core INPUTA1.0001.000-0.483-0.473-0.1290.538
6zoy-rbd.pdbA28N Core INPUTA1.0001.000-0.483-0.7670.115-0.394
6zoy-rbd.pdbA28P Core INPUTA1.0001.000-0.4836.895-1.086-2.253
6zoy-rbd.pdbA28Q Core INPUTA1.0001.000-0.4830.351-0.202-0.916
6zoy-rbd.pdbA28R Core INPUTA1.0001.000-0.483-0.6730.083-0.735
6zoy-rbd.pdbA28S Core INPUTA1.0001.000-0.483-0.042-0.043-1.275
6zoy-rbd.pdbA28T Core INPUTA1.0001.000-0.483-0.005-0.071-0.029
6zoy-rbd.pdbA28V Core INPUTA1.0001.000-0.483-0.1250.2950.401
6zoy-rbd.pdbA28W Core INPUTA1.0001.000-0.483-2.0340.2661.357
6zoy-rbd.pdbA28Y Core INPUTA1.0001.000-0.483-1.3120.1370.889
6zoy-rbd.pdbA32C Core INPUTA1.0001.000-0.483-1.4000.0420.001
6zoy-rbd.pdbA32D Core INPUTA1.0001.000-0.483-0.197-0.122-1.290
6zoy-rbd.pdbA32E Core INPUTA1.0001.000-0.483-0.289-0.384-0.967
6zoy-rbd.pdbA32F Core INPUTA1.0001.000-0.483-1.100-0.0160.507
6zoy-rbd.pdbA32G Core INPUTA1.0001.000-0.483-0.4810.540-1.670
6zoy-rbd.pdbA32H Core INPUTA1.0001.000-0.483-0.061-0.185-0.338
6zoy-rbd.pdbA32I Core INPUTA1.0001.000-0.483-0.850-0.4031.021
6zoy-rbd.pdbA32K Core INPUTA1.0001.000-0.483-0.431-0.428-1.263
6zoy-rbd.pdbA32L Core INPUTA1.0001.000-0.483-1.181-0.5850.219
6zoy-rbd.pdbA32M Core INPUTA1.0001.000-0.483-0.731-0.4410.394
6zoy-rbd.pdbA32N Core INPUTA1.0001.000-0.4831.797-0.585-1.522
6zoy-rbd.pdbA32P Core INPUTA1.0001.000-0.483-1.2690.6560.222
6zoy-rbd.pdbA32Q Core INPUTA1.0001.000-0.483-0.150-0.289-0.796
6zoy-rbd.pdbA32R Core INPUTA1.0001.000-0.483-0.611-0.240-0.909
6zoy-rbd.pdbA32S Core INPUTA1.0001.000-0.4830.419-0.197-0.755
6zoy-rbd.pdbA32T Core INPUTA1.0001.000-0.4830.069-0.192-0.478
6zoy-rbd.pdbA32V Core INPUTA1.0001.000-0.483-0.550-0.138-0.201
6zoy-rbd.pdbA32W Core INPUTA1.0001.000-0.483-2.3000.2370.953
6zoy-rbd.pdbA32Y Core INPUTA1.0001.000-0.483-0.631-0.0070.114
6zoy-rbd.pdbA43C Core INPUTA1.0001.000-0.483-0.999-0.8500.605
6zoy-rbd.pdbA43D Core INPUTA1.0001.000-0.483-2.2491.7242.288
6zoy-rbd.pdbA43E Core INPUTA1.0001.000-0.483-1.8990.8552.279
6zoy-rbd.pdbA43F Core INPUTA1.0001.000-0.4834.202-2.4842.142
6zoy-rbd.pdbA43G Core INPUTA1.0001.000-0.483-1.7500.5741.114
6zoy-rbd.pdbA43H Core INPUTA1.0001.000-0.483-0.4490.8392.178
6zoy-rbd.pdbA43I Core INPUTA1.0001.000-0.4830.154-0.7671.465
6zoy-rbd.pdbA43K Core INPUTA1.0001.000-0.483-1.8991.6462.336
6zoy-rbd.pdbA43L Core INPUTA1.0001.000-0.4830.153-0.7771.663
6zoy-rbd.pdbA43M Core INPUTA1.0001.000-0.4830.153-1.2681.691
6zoy-rbd.pdbA43N Core INPUTA1.0001.000-0.483-2.1490.9532.041
6zoy-rbd.pdbA43P Core INPUTA1.0001.000-0.483-2.6491.0380.474
6zoy-rbd.pdbA43Q Core INPUTA1.0001.000-0.483-1.799-0.1672.224
6zoy-rbd.pdbA43R Core INPUTA1.0001.000-0.483-1.8990.9342.103
6zoy-rbd.pdbA43S Core INPUTA1.0001.000-0.483-0.7500.2320.741
6zoy-rbd.pdbA43T Core INPUTA1.0001.000-0.483-0.998-0.0971.318
6zoy-rbd.pdbA43V Core INPUTA1.0001.000-0.483-0.246-0.4760.875
6zoy-rbd.pdbA43W Core INPUTA1.0001.000-0.4830.602-1.7171.956
6zoy-rbd.pdbA43Y Core INPUTA1.0001.000-0.4832.652-3.0892.256
6zoy-rbd.pdbA52C Core INPUTA1.0001.000-0.483-0.5510.1250.843
6zoy-rbd.pdbA52D Core INPUTA1.0001.000-0.483-2.0510.379-0.892
6zoy-rbd.pdbA52E Core INPUTA1.0001.000-0.483-1.6010.253-0.827
6zoy-rbd.pdbA52F Core INPUTA1.0001.000-0.4830.348-0.2490.964
6zoy-rbd.pdbA52G Core INPUTA1.0001.000-0.483-2.4510.467-0.170
6zoy-rbd.pdbA52H Core INPUTA1.0001.000-0.483-1.6510.2120.338
6zoy-rbd.pdbA52I Core INPUTA1.0001.000-0.4831.898-0.3490.995
6zoy-rbd.pdbA52K Core INPUTA1.0001.000-0.483-1.3510.118-0.501
6zoy-rbd.pdbA52L Core INPUTA1.0001.000-0.4831.698-0.3520.620
6zoy-rbd.pdbA52M Core INPUTA1.0001.000-0.4831.098-0.3280.795
6zoy-rbd.pdbA52N Core INPUTA1.0001.000-0.483-1.5010.209-0.090
6zoy-rbd.pdbA52P Core INPUTA1.0001.000-0.483-1.1020.126-1.446
6zoy-rbd.pdbA52Q Core INPUTA1.0001.000-0.483-1.3510.166-0.071
6zoy-rbd.pdbA52R Core INPUTA1.0001.000-0.483-1.602-0.033-0.358
6zoy-rbd.pdbA52S Core INPUTA1.0001.000-0.483-0.4000.240-1.876
6zoy-rbd.pdbA52T Core INPUTA1.0001.000-0.4831.246-0.278-0.901
6zoy-rbd.pdbA52V Core INPUTA1.0001.000-0.4831.848-0.2790.325
6zoy-rbd.pdbA52W Core INPUTA1.0001.000-0.483-1.5520.1230.949
6zoy-rbd.pdbA52Y Core INPUTA1.0001.000-0.483-0.352-0.0350.850
6zoy-rbd.pdbA77C Core INPUTA1.0001.000-0.483-1.420-0.0291.521
6zoy-rbd.pdbA77D Core INPUTA1.0001.000-0.483-3.5532.4863.067
6zoy-rbd.pdbA77F Core INPUTA1.0001.000-0.483-1.553-0.8482.237
6zoy-rbd.pdbA77G Core INPUTA1.0001.000-0.483-3.2381.4912.319
6zoy-rbd.pdbA77H Core INPUTA1.0001.000-0.483-3.3780.4702.530
6zoy-rbd.pdbA77I Core INPUTA1.0001.000-0.4831.182-2.0691.790
6zoy-rbd.pdbA77L Core INPUTA1.0001.000-0.4830.481-2.8411.983
6zoy-rbd.pdbA77N Core INPUTA1.0001.000-0.483-3.3780.2573.014
6zoy-rbd.pdbA77P Core INPUTA1.0001.000-0.483-2.8270.6422.236
6zoy-rbd.pdbA77R Core INPUTA1.0001.000-0.483-2.9210.8842.902
6zoy-rbd.pdbA77S Core INPUTA1.0001.000-0.483-1.8230.6721.305
6zoy-rbd.pdbA77T Core INPUTA1.0001.000-0.483-1.1300.4331.624
6zoy-rbd.pdbA77V Core INPUTA1.0001.000-0.4831.315-1.4401.108
6zoy-rbd.pdbA77Y Core INPUTA1.0001.000-0.483-1.977-0.7522.484
6zoy-rbd.pdbA91C Core INPUTA1.0001.000-0.483-2.0460.2331.813
6zoy-rbd.pdbA91D Core INPUTA1.0001.000-0.483-1.2041.0320.719
6zoy-rbd.pdbA91E Core INPUTA1.0001.000-0.483-0.0300.2200.238
6zoy-rbd.pdbA91F Core INPUTA1.0001.000-0.483-2.1290.3872.128
6zoy-rbd.pdbA91G Core INPUTA1.0001.000-0.483-1.9390.4030.430
6zoy-rbd.pdbA91H Core INPUTA1.0001.000-0.483-1.1630.4400.965
6zoy-rbd.pdbA91I Core INPUTA1.0001.000-0.483-1.4960.8431.649
6zoy-rbd.pdbA91K Core INPUTA1.0001.000-0.4830.112-0.4610.449
6zoy-rbd.pdbA91L Core INPUTA1.0001.000-0.483-0.9960.2081.313
6zoy-rbd.pdbA91M Core INPUTA1.0001.000-0.483-0.296-0.0340.914
6zoy-rbd.pdbA91N Core INPUTA1.0001.000-0.483-0.8460.8590.795
6zoy-rbd.pdbA91P Core INPUTA1.0001.000-0.483-1.5621.3641.612
6zoy-rbd.pdbA91Q Core INPUTA1.0001.000-0.4831.262-0.869-0.003
6zoy-rbd.pdbA91R Core INPUTA1.0001.000-0.483-0.0380.0540.810
6zoy-rbd.pdbA91S Core INPUTA1.0001.000-0.483-0.340-0.210-0.223
6zoy-rbd.pdbA91T Core INPUTA1.0001.000-0.483-0.9310.7220.260
6zoy-rbd.pdbA91V Core INPUTA1.0001.000-0.483-0.9640.7310.939
6zoy-rbd.pdbA91W Core INPUTA1.0001.000-0.483-2.4610.8391.686
6zoy-rbd.pdbA91Y Core INPUTA1.0001.000-0.483-1.2290.3681.590
6zoy-rbd.pdbA99C Core INPUTA1.0001.000-0.483-2.4010.492-0.555
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