ELASPIC home << Job #oncokb << Q92963.F82L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q92963.F82L

Detailed results for job #oncokb produced by ELASPIC
Q92963, GTP-binding protein Rit1:
F82L
1
219
Ras
MERL isoform 6, Isoform 6 of Merlin:
1
548
ERM
FERM_M
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Q92963.F82L

Completed successfully

Protein, domain: Q92963 Ras

Interacting with: MERL isoform 6 FERM_M

PDB templates used: 4dxa_A, 4dxa_B

Seq identity: 0.500, 0.272 Model score: 0.210

ELASPIC ΔΔG: 0.128

ELASPIC2 (EL2) score: 1.511

Mutation in databases: UniProt, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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