ELASPIC home << Job #oncokb << Q13485.R420H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q13485.R420H

Detailed results for job #oncokb produced by ELASPIC
Q13485, Mothers against decapentaplegic homolog 4:
R420H
1
552
MH1
MH2
SKIL isoform 3, Isoform SNON2 of Ski-like protein:
1
638
c-SKI_SMAD..
Ski_Sno
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Q13485.R420H

Completed successfully

Protein, domain: Q13485 MH2

Interacting with: SKIL isoform 3 c-SKI_SMAD_bind

PDB templates used: 1mr1_B, 1mr1_C

Seq identity: 0.832, 0.495 Model score: 0.175

ELASPIC ΔΔG: -0.138

ELASPIC2 (EL2) score: 0.985

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.