ELASPIC home << Job #oncokb << Q06124.Y63C
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q06124.Y63C

Detailed results for job #oncokb produced by ELASPIC
Q06124, Tyrosine-protein phosphatase non-receptor type 11:
Y63C
1
597
SH2
SH2
Y_phosphatase
GSK3B isoform 2, Isoform 2 of Glycogen synthase kinase-3 beta:
1
433
Pkinase
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Q06124.Y63C

Completed successfully

Protein, domain: Q06124 SH2

Interacting with: GSK3B isoform 2 Pkinase

PDB templates used: 4gl9_E, 4gl9_A

Seq identity: 0.329, 0.304 Model score: 0.429

ELASPIC ΔΔG: 0.814

ELASPIC2 (EL2) score: 1.463

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.