ELASPIC home << Job #oncokb << Q02750.D65N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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Q02750.D65N

Detailed results for job #oncokb produced by ELASPIC
Q02750, Dual specificity mitogen-activated protein kinase kinase 1:
D65N
1
393
Pkinase
MAP2K4, Dual specificity mitogen-activated protein kinase kinase 4:
1
399
Pkinase
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Protein: Q02750 | MAP2K4 | Cofactors | All
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Q02750.D65N

Completed successfully

Protein, domain: Q02750 Pkinase

Interacting with: MAP2K4 Pkinase

PDB templates used: 3aln_B, 3aln_A

Seq identity: 0.334, 0.879 Model score: 0.457

ELASPIC ΔΔG: 1.712

ELASPIC2 (EL2) score: -0.100

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.