ELASPIC home << Job #oncokb << P63000.Q61R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P63000.Q61R

Detailed results for job #oncokb produced by ELASPIC
P63000, Ras-related C3 botulinum toxin substrate 1:
Q61R
1
192
Ras
DIAPH1, Protein diaphanous homolog 1:
1
1272
Drf_GBD+Drf_FH3
FH2
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Protein: P63000 | DIAPH1 | Cofactors | All
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P63000.Q61R

Completed successfully

Protein, domain: P63000 Ras

Interacting with: DIAPH1 Drf_GBD+Drf_FH3

PDB templates used: 3eg5_A, 3eg5_B

Seq identity: 0.729, 0.901 Model score: -0.837

ELASPIC ΔΔG: 0.492

ELASPIC2 (EL2) score: 2.614

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

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