ELASPIC home << Job #oncokb << P61586.E40W
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P61586.E40W

Detailed results for job #oncokb produced by ELASPIC
P61586, Transforming protein RhoA:
E40W
1
193
Ras
DOCK7 isoform 4, Isoform 4 of Dedicator of cytokinesis protein 7:
1
2098
Ded_cyto
DOCK..
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P61586.E40W

Completed successfully

Protein, domain: P61586 Ras

Interacting with: DOCK7 isoform 4 Ded_cyto

PDB templates used: 3vhl_B, 3vhl_A

Seq identity: 0.546, 0.736 Model score: -1.073

ELASPIC ΔΔG: 2.719

ELASPIC2 (EL2) score: 2.503

Mutation run by user.

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Citation

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