ELASPIC home << Job #oncokb << P38398.A1830T
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P38398.A1830T

Detailed results for job #oncokb produced by ELASPIC
P38398, Breast cancer type 1 susceptibility protein:
A1830T
1
1863
zf..
BRCT
BRCA1 isoform 6, Isoform 6 of Breast cancer type 1 susceptibility protein:
1
699
zf-C3HC4
BRCT
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P38398.A1830T

Completed successfully

Protein, domain: P38398 BRCT

Interacting with: BRCA1 isoform 6 BRCT

PDB templates used: 3pxe_B, 3pxe_A

Seq identity: 0.995, 1.000 Model score: -0.449

ELASPIC ΔΔG: 3.302

ELASPIC2 (EL2) score: -1.602

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.