ELASPIC home << Job #oncokb << P36507.S154F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P36507.S154F

Detailed results for job #oncokb produced by ELASPIC
P36507, Dual specificity mitogen-activated protein kinase kinase 2:
S154F
1
400
Pkinase
PRKCD, Protein kinase C delta type:
1
676
C1_1
C1_1
Pkinase+Pkinase_C
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Protein: P36507 | PRKCD | Cofactors | All
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P36507.S154F

Completed successfully

Protein, domain: P36507 Pkinase

Interacting with: PRKCD Pkinase+Pkinase_C

PDB templates used: 2y4i_C, 2y4i_B

Seq identity: 0.791, 0.280 Model score: 0.767

ELASPIC ΔΔG: 0.854

ELASPIC2 (EL2) score: 2.555

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.