ELASPIC home << Job #oncokb << P35968.D717V
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P35968.D717V

Detailed results for job #oncokb produced by ELASPIC
P35968, Vascular endothelial growth factor receptor 2:
D717V
1
1356
Pkinase_Tyr
V-set
I-set
Ig_2
I-set
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P35968.D717V

Completed successfully

Protein, domain: P35968 I-set

Type: Core (stability)

PDB template used: 3kvq_A

Seq identity: 1.000 Model score: -1.344

ELASPIC ΔΔG: 1.079

ELASPIC2 (EL2) score: 1.385

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.