ELASPIC home << Job #oncokb << P31751.H355M
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P31751.H355M

Detailed results for job #oncokb produced by ELASPIC
P31751, RAC-beta serine/threonine-protein kinase:
H355M
1
481
PH
Pkinase+Pkinase_C
PDPK1 isoform 5, Isoform 5 of 3-phosphoinositide-dependent protein kinase 1:
1
454
Pkinase
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P31751.H355M

Completed successfully

Protein, domain: P31751 Pkinase+Pkinase_C

Interacting with: PDPK1 isoform 5 Pkinase

PDB templates used: 3qc4_B, 3qc4_A

Seq identity: 0.387, 0.968 Model score: 0.079

ELASPIC ΔΔG: 5.292

ELASPIC2 (EL2) score: 1.840

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.