ELASPIC home << Job #oncokb << P31751.H355M
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P31751.H355M

Detailed results for job #oncokb produced by ELASPIC
P31751, RAC-beta serine/threonine-protein kinase:
H355M
1
481
PH
Pkinase+Pkinase_C
TRIB3, Tribbles homolog 3:
1
358
Pkinase
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Protein: P31751 | TRIB3 | Cofactors | All
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P31751.H355M

Completed successfully

Protein, domain: P31751 Pkinase+Pkinase_C

Interacting with: TRIB3 Pkinase

PDB templates used: 3o7l_D, 3o7l_B

Seq identity: 0.433, 0.242 Model score: 0.723

ELASPIC ΔΔG: 2.677

ELASPIC2 (EL2) score: 2.007

Mutation run by user.

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Citation

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