ELASPIC home << Job #oncokb << P31749.K179M
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P31749.K179M

Detailed results for job #oncokb produced by ELASPIC
P31749, RAC-alpha serine/threonine-protein kinase:
K179M
1
480
PH
Pkinase+Pkinase_C
CDKN1B, Cyclin-dependent kinase inhibitor 1B:
1
198
CDI
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Protein: P31749 | CDKN1B | Cofactors | All
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P31749.K179M

Completed successfully

Protein, domain: P31749 Pkinase+Pkinase_C

Interacting with: CDKN1B CDI

PDB templates used: 1jsu_A, 1jsu_C

Seq identity: 0.268, 1.000 Model score: 0.605

ELASPIC ΔΔG: 0.653

ELASPIC2 (EL2) score: 1.865

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.