ELASPIC home << Job #oncokb << P21802.P253R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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P21802.P253R

Detailed results for job #oncokb produced by ELASPIC
P21802, Fibroblast growth factor receptor 2:
P253R
1
821
I-set
I-set
Pkinase_Tyr
FGF23, Fibroblast growth factor 23:
1
251
FGF
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Model: Wild-type | Mutant | Both
Protein: P21802 | FGF23 | Cofactors | All
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P21802.P253R

Completed successfully

Protein, domain: P21802 I-set

Interacting with: FGF23 FGF

PDB templates used: 1iil_G, 1iil_C

Seq identity: 0.991, 0.309 Model score: 0.270

ELASPIC ΔΔG: 0.812

ELASPIC2 (EL2) score: -0.308

Mutation in databases: UniProt, COSMIC, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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