ELASPIC home << Job #oncokb << P16234.G853D
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

P16234.G853D

Detailed results for job #oncokb produced by ELASPIC
P16234, Platelet-derived growth factor receptor alpha:
G853D
1
1089
Pkinase_Tyr
Ig_2
I-set
PGFRA isoform 3, Isoform 3 of Platelet-derived growth factor receptor alpha:
1
743
I-set+I-set
Pkinase_Tyr
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P16234.G853D

Completed successfully

Protein, domain: P16234 Pkinase_Tyr

Interacting with: PGFRA isoform 3 Pkinase_Tyr

PDB templates used: 3kxx_C, 3kxx_B

Seq identity: 0.545, 0.500 Model score: 1.012

ELASPIC ΔΔG: 0.700

ELASPIC2 (EL2) score: 0.040

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.