ELASPIC home << Job #oncokb << P15056.G478C
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P15056.G478C

Detailed results for job #oncokb produced by ELASPIC
P15056, Serine/threonine-protein kinase B-raf:
G478C
1
766
RBD
C1_1
Pkinase_Tyr
MK03 isoform 2, Isoform 2 of Mitogen-activated protein kinase 3:
1
335
Pkinase
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P15056.G478C

Completed successfully

Protein, domain: P15056 Pkinase_Tyr

Interacting with: MK03 isoform 2 Pkinase

PDB templates used: 1uwj_A, 1uwj_B

Seq identity: 0.953, 0.244 Model score: 0.280

ELASPIC ΔΔG: 0.957

ELASPIC2 (EL2) score: 1.890

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.