ELASPIC home << Job #oncokb << P04637.R181H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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P04637.R181H

Detailed results for job #oncokb produced by ELASPIC
P04637, Cellular tumor antigen p53:
R181H
1
393
P53_TAD
P53+P53_tetramer
BARD1, BRCA1-associated RING domain protein 1:
1
777
zf-RING_6
Ank
BRCT
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Protein: P04637 | BARD1 | Cofactors | All
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P04637.R181H

Completed successfully

Protein, domain: P04637 P53+P53_tetramer

Interacting with: BARD1 Ank

PDB templates used: 1ycs_A, 1ycs_B

Seq identity: 1.000, 0.316 Model score: -0.304

ELASPIC ΔΔG: 1.596

ELASPIC2 (EL2) score: -0.119

Mutation in databases: UniProt, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.