ELASPIC home << Job #oncokb << P04637.H168R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P04637.H168R

Detailed results for job #oncokb produced by ELASPIC
P04637, Cellular tumor antigen p53:
H168R
1
393
P53_TAD
P53+P53_tetramer
LYN isoform 2, Isoform 2 of Tyrosine-protein kinase Lyn:
1
491
SH3_1
SH2
Pkinase_Tyr
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P04637.H168R

Completed successfully

Protein, domain: P04637 P53+P53_tetramer

Interacting with: LYN isoform 2 SH3_1

PDB templates used: 1ycs_A, 1ycs_B

Seq identity: 1.000, 0.333 Model score: -0.113

ELASPIC ΔΔG: 1.941

ELASPIC2 (EL2) score: 0.093

Mutation in databases: UniProt, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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