ELASPIC home << Job #oncokb << P03372.S463P
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P03372.S463P

Detailed results for job #oncokb produced by ELASPIC
P03372, Estrogen receptor:
S463P
1
595
zf-C4+Hormone_recep
HNF4A isoform 4, Isoform HNF4-Alpha-4 of Hepatocyte nuclear factor 4-alpha:
1
504
zf-C4
Hormone_recep
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P03372.S463P

Completed successfully

Protein, domain: P03372 zf-C4+Hormone_recep

Interacting with: HNF4A isoform 4 Hormone_recep

PDB templates used: 1gwr_A, 1gwr_B

Seq identity: 0.975, 0.253 Model score: -0.082

ELASPIC ΔΔG: 0.021

ELASPIC2 (EL2) score: -1.335

Mutation run by user.

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Citation

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