ELASPIC home << Job #oncokb << P01116.S65N
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01116.S65N

Detailed results for job #oncokb produced by ELASPIC
P01116, GTPase KRas:
S65N
1
189
Ras
RASGRP3, Ras guanyl-releasing protein 3:
1
690
RasGEF_N+RasGEF
EF..
C1_1
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Protein: P01116 | RASGRP3 | Cofactors | All
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P01116.S65N

Completed successfully

Protein, domain: P01116 Ras

Interacting with: RASGRP3 RasGEF_N+RasGEF

PDB templates used: 4nyi_R, 4nyi_S

Seq identity: 0.940, 0.229 Model score: 0.176

ELASPIC ΔΔG: -1.120

ELASPIC2 (EL2) score: 1.969

Mutation run by user.

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Citation

If you use these results, please cite the papers on this page.