ELASPIC home << Job #oncokb << P01116.Q25H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01116.Q25H

Detailed results for job #oncokb produced by ELASPIC
P01116, GTPase KRas:
Q25H
1
189
Ras
L7RRS6, V-raf-1 murine leukemia viral oncogene homolog 1:
1
648
RBD
C1_1
Pkinase_Tyr
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Protein: P01116 | L7RRS6 | Cofactors | All
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P01116.Q25H

Completed successfully

Protein, domain: P01116 Ras

Interacting with: L7RRS6 RBD

PDB templates used: 4g0n_A, 4g0n_B

Seq identity: 0.928, 1.000 Model score: -1.285

ELASPIC ΔΔG: 1.021

ELASPIC2 (EL2) score: 1.328

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.