ELASPIC home << Job #oncokb << P01112.T58I
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01112.T58I

Detailed results for job #oncokb produced by ELASPIC
P01112, GTPase HRas:
T58I
1
189
Ras
AFAD isoform 2, Isoform 1 of Afadin:
1
1612
DIL
PDZ
FHA
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P01112.T58I

Completed successfully

Protein, domain: P01112 Ras

Interacting with: AFAD isoform 2 DIL

PDB templates used: 4lx0_C, 4lx0_D

Seq identity: 0.377, 0.222 Model score: 0.666

ELASPIC ΔΔG: 0.411

ELASPIC2 (EL2) score: 1.342

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.