ELASPIC home << Job #oncokb << P01112.Q61R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01112.Q61R

Detailed results for job #oncokb produced by ELASPIC
P01112, GTPase HRas:
Q61R
1
189
Ras
ITSN1 isoform 9, Isoform 9 of Intersectin-1:
1
1660
C2
RhoGEF
SH..
EF-..
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P01112.Q61R

Completed successfully

Protein, domain: P01112 Ras

Interacting with: ITSN1 isoform 9 RhoGEF

PDB templates used: 1kz7_D, 1kz7_C

Seq identity: 0.333, 0.266 Model score: 0.063

ELASPIC ΔΔG: 0.944

ELASPIC2 (EL2) score: 2.633

Mutation in databases: COSMIC, COSMIC, COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.