ELASPIC home << Job #oncokb << P01112.P34R
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01112.P34R

Detailed results for job #oncokb produced by ELASPIC
P01112, GTPase HRas:
P34R
1
189
Ras
ITSN1 isoform 4, Isoform 4 of Intersectin-1:
1
1650
C2
RhoGEF
SH..
EF-..
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P01112.P34R

Completed successfully

Protein, domain: P01112 Ras

Interacting with: ITSN1 isoform 4 RhoGEF

PDB templates used: 2vrw_A, 2vrw_B

Seq identity: 0.315, 0.242 Model score: -0.404

ELASPIC ΔΔG: 1.668

ELASPIC2 (EL2) score: 2.238

Mutation run by user.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.