ELASPIC home << Job #oncokb << P01111.Q61L
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
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P01111.Q61L

Detailed results for job #oncokb produced by ELASPIC
P01111, GTPase NRas:
Q61L
1
189
Ras
ARHGAP4, Rho GTPase-activating protein 4:
1
946
SH3_1
FCH
RhoGAP
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Protein: P01111 | ARHGAP4 | Cofactors | All
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P01111.Q61L

Completed successfully

Protein, domain: P01111 Ras

Interacting with: ARHGAP4 RhoGAP

PDB templates used: 3msx_A, 3msx_B

Seq identity: 0.307, 0.296 Model score: -0.365

ELASPIC ΔΔG: 0.044

ELASPIC2 (EL2) score: 1.925

Mutation in databases: COSMIC, COSMIC, COSMIC.

Download:  PDBwt   | PDBmut

Citation

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