ELASPIC home << Job #oncokb << P00533.R776H
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
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ELASPIC2 (EL2) score
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P00533.R776H

Detailed results for job #oncokb produced by ELASPIC
P00533, Epidermal growth factor receptor:
R776H
1
1210
Recep_L_d..
Recep_..
Furin..
Pkinase_Tyr
ERBB3, Receptor tyrosine-protein kinase erbB-3:
1
1342
Pkinase_Tyr
Recep_..
Furin-l..
Recep_L_..
GF_re..
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Protein: P00533 | ERBB3 | Cofactors | All
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P00533.R776H

Completed successfully

Protein, domain: P00533 Pkinase_Tyr

Interacting with: ERBB3 Pkinase_Tyr

PDB templates used: 4i24_B, 4i24_A

Seq identity: 0.962, 0.589 Model score: -0.673

ELASPIC ΔΔG: 2.835

ELASPIC2 (EL2) score: 0.508

Mutation in database: COSMIC.

Download:  PDBwt   | PDBmut

Citation

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