ELASPIC home << Job #oncokb << O96017.S428F
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ELASPIC ΔΔG
The final Gibbs free energy change (ΔΔG) in kcal/mol is predicted using more than 70 sequential, molecular and energetic features with the Stochastic Gradient Boosting of Decision Trees algorithm.
For more information see the ELASPIC publication.
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ELASPIC2 (EL2) score
The ELASPIC2 (EL2) score is obtained using features generated by pretrained ProteinSolver and ProtBert neural networks with the Stochastic Gradient Boosting of Decision Trees algorithm and a ranking objective function.
For more information see the ELASPIC2 (EL2) publication.

O96017.S428F

Detailed results for job #oncokb produced by ELASPIC
O96017, Serine/threonine-protein kinase Chk2:
S428F
1
543
FHA
Pkinase
SRPK1, SRSF protein kinase 1:
1
655
Pkinase
Pkinase
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Protein: O96017 | SRPK1 | Cofactors | All
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O96017.S428F

Completed successfully

Protein, domain: O96017 Pkinase

Interacting with: SRPK1 Pkinase

PDB templates used: 2oza_A, 2oza_B

Seq identity: 0.350, 0.291 Model score: 1.129

ELASPIC ΔΔG: 0.749

ELASPIC2 (EL2) score: -0.961

Mutation in database: UniProt.

Download:  PDBwt   | PDBmut

Citation

If you use these results, please cite the papers on this page.