>gi|1857986|gb|AAC51916.1| phosphodiesterase 4C [Homo sapiens]
AVQKRSRAVGARSSLHAVLAMQGPPAPAPVPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGR
RALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAAL
ARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETS
RSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGL
DVFKVAELSGNQPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAV
FTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMV
IDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQG
DRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDG
PDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPAPGDLPLDNQRT
>gi|149363646|ref|NP_001092288.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform PDE4C3 [Homo sapiens] >gi|119605081|gb|EAW84675.1| phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila), isoform CRA_a [Homo sapiens]
MQGPPAPAPVPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGRRALDPQSSPGLGRIMQAPVP
HSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSS
NQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTE
VELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFS
IFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDH
PGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLK
TMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTAS
VEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEE
EEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|221043422|dbj|BAH13388.1| unnamed protein product [Homo sapiens]
MQGPPAPAPVPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGRRALDPQSSPGLGRIMQAPVP
HSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSS
NQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTE
VELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFS
IFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDH
PGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLK
TMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDVSPMCDKHTAS
VEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLINPERDGPDRFQFELTLEEAEEEDEEE
EEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|5690363|gb|AAD47054.1| cAMP specific phosphodiesterase PDE4C3 variant [Homo sapiens]
MQGPPAPAPVPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGRRALDPQSSPGLGRIMQAPVP
HSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSS
NQLPPAEDTGQNLALETLYELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTE
VELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFS
IFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDH
PGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLK
TMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTAS
VEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEE
EEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|115529445|ref|NP_000914.2| cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform PDE4C1 [Homo sapiens] >gi|20141263|sp|Q08493.2|PDE4C_HUMAN RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C; AltName: Full=DPDE1; AltName: Full=PDE21 [Homo sapiens] >gi|119605083|gb|EAW84677.1| phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila), isoform CRA_c [Homo sapiens] >gi|193787833|dbj|BAG53036.1| unnamed protein product [Homo sapiens] >gi|307686199|dbj|BAJ21030.1| phosphodiesterase 4C, cAMP-specific [synthetic construct]
MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCR
RFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLA
SLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQL
AKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQST
HVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQW
TDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPR
SPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|2706887|gb|AAB96875.1| PDE4C-791, partial [Homo sapiens]
GTQAGLRSGAPSGHRQLLGVGPTLSPSSTFYRFSTSGADSSSLSPPLPALGRTREQTLLGARSRGRVLLPAIPDPFLWRM
ENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCRR
FDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLAS
LRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRIL
NRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLA
KELEDTNKWGLDVFKVAELSGNQPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTH
VLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLS
AKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWT
DRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRS
PSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|221040564|dbj|BAH11959.1| unnamed protein product [Homo sapiens]
MQRYRGRQTVFGAGVLGGVSSAPSFNTPSPRSSPLFYPSAPSGHRQLLGVGPTLSPSSTFYRFSTSGADSSSLSPPLPAL
GRTREQTLLGARSRGRVLLPAIPDPFLWRMENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPD
KSAGCRERDLSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELS
PKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLD
ELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRIS
GLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLA
TYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMY
NDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNY
SDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWET
WADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDT
ELLSPEAGPDPGDLPLDNQRT
>gi|3688084|gb|AAC83050.1| PDE4C-791 [Homo sapiens]
APSGHRQLLGVGPTLSPSSTFYRFSTSGADSSSLSPPLPALGRTREQTLLGARSRGRVLLPAIPDPFLWRMENLGVGEGA
EACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCRRFDLENGLSC
GRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVA
ALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSE
TSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKW
GLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALE
AVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRR
MVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQ
QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPER
DGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|727223|emb|CAA86601.1| 3',5'-cyclic AMP phosphodiesterase [Homo sapiens]
MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCR
RFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLA
SLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQL
AKELEDTNKWGLDVFKVADVSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQST
HVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSDVALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQW
TDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPR
SPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|5690362|gb|AAD47053.1| cAMP specific phosphodiesterase PDE4C1 variant [Homo sapiens]
MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCR
RFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLA
SLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQNLALETLYELDWCLDQLETLQTRHSVGEMASNKFKRI
LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQL
AKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQST
HVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQW
TDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPR
SPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|397493885|ref|XP_003817826.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Pan paniscus]
MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCR
RFDLENGLSCGRRAPDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLA
SLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKR
ILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSANLSSATVPRFGVQTDQEEQ
LAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQS
THVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQN
LSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQ
WTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIP
RSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|3688080|gb|AAC83047.1| CN4C_HUMAN [Homo sapiens]
MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCR
RFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLA
SLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQL
AKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQST
HVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTKLALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSA
KQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTD
RIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSP
SDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|395750739|ref|XP_002828968.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform 1 [Pongo abelii] >gi|395750741|ref|XP_003779146.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform 2 [Pongo abelii]
MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRESDLSPRPELRKSRLSWPVSSCR
RFDLENGLSCGRRALDPQSSPGLGRVMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLA
SLRTVRSNVAALARLQCLGAAKQGPVGNPSSSNQPPPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKR
ILNRELTHLSETSRSGNQVSQYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLRGLCQSASLSSATVPRFGVQTDQEEQ
LAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHASVAYHNSLHAADVAQS
THVLLATPALQAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNIFQN
LSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQ
WTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIP
RSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEEEGEETALDKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|635037062|ref|XP_007993973.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Chlorocebus sabaeus]
MQRXRERQTVLRAGVGGLFSPXLQHPSPRSFPLFYPSAPSGHRQLLGFGPSLSPRSTFSRFSTSGADSSSLSPPLPALGQ
TREQTLFGVRSRGRLLLPAIPDPFLWXMETLGVSEGAEVCSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKS
AGCRERDLSPRPGLGKSRLSWPISSCRRFDLENGLSCGRRALDPQSSPGLGRVMQAPVQHSQRRESFLYRSDSDYELSPK
AVSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARLQCLGAAKQGPVGNPSSSNQPPPPAEDTGQKLALETLDE
LDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISG
LHGLCHGASLSSATVPRFGVQTDQEEQLAKELEDTNRWGLDVFKVAELSGNRPLTAVLFSIFQERDLLKTFQIPADTLAT
YLLMLEGHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYN
DASVLENHHLAVGFKLLQAKNCDIFQNLSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYS
DRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFHQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETW
ADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPEWGGPDRFQFELTLEEAEEEEEEEEEDGEETALDKEALELPDTE
LLSPEAGPDPGDLPLDNQRT
>gi|544509644|ref|XP_005588486.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Macaca fascicularis]
METLGVSEGAEVCSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGRRERDLSPRPGLGKSRLSWPISSCR
RFDLENGLSCGRRALDPQSSPGLGRVMQAPVPHTQRRESFLYRSDSDYELSPKAVSRNSSVASDLHGEDMIVTPFAQVLA
SLRTVRSNVAALARLQCLGAAKQGPVGNPSSSNQPPPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKR
ILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHGASLSSATVPRFGVQTDQEEQ
LAKELEDTNRWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHADVAYHNSLHAADVAQS
THVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAKNCDIFQN
LSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQ
WTDRIMAEFFHQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIP
RSPSDLTNPEWGGPDRFQFELTLEEAEEEDEEEEEDGXERALDKDALKLPDTELLSPEAGPDPGDLPLDNQRT
>gi|1857984|gb|AAC51915.1| phosphodiesterase 4C [Homo sapiens]
MQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPV
GNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTF
LDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNQPL
TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASA
IHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMN
LLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMC
DKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAE
EEDEEEEEEGEETALAKEALELPDTELLSPEAGPAPGDLPLDNQRT
>gi|402904776|ref|XP_003915216.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Papio anubis]
MWCSPPRLKGQRKDRVVPGSTIWASTAPRLRPHLEPPFHLLPLQHLRRGQLLAVASTPGPGPDPRADAPRRPLTGTTPAP
CYPKPLSLAMETLGVSEGAEVCSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGRRERDLSPRPGLGKSR
LSWPISSCRRFDLENGLSCGRRALDPQSSPGLGRVIQAPVSHSQRRESFLYRSDSDYELSPKAVSRNSSVASDLHGEDMI
VTPFAQVLASLRTVRSNVAALACLQCLGAAKQGPVGNPSSSNQPPPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVG
EMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHGASLSSATVPRF
GVQTDQEEQLAKELEDTNRWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHADVAYHNS
LHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQ
AKNCDIFQNLSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNP
TKPLPLYRQWTDRIMAEFFHQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDN
REWYQSKIPRSPSDLTNPEWGGPDRFQFELTLEEAEEEDEEEEEDGEETALDKEALELPNTELLSPEAGPDPGDLPLDNQ
RT
>gi|149363666|ref|NP_001092289.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform PDE4C2 [Homo sapiens]
MQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPV
GNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTF
LDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPL
TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASA
IHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMN
LLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMC
DKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAE
EEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|5690364|gb|AAD47055.1| cAMP specific phosphodiesterase PDE4C2 variant [Homo sapiens]
MQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPV
GNPSSSNQLPPAEDTGQNLALETLYELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTF
LDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPL
TAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASA
IHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMN
LLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMC
DKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAE
EEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|395847915|ref|XP_003796609.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Otolemur garnettii]
MQGPPAPVPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLPGGRSTLDPQSGPGLGRAIHAPAP
HSQRRESFLYRSDSDYELSPKAISRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGRGAAKQASVGNPTCS
SQPPPSTEDNGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQET
EVELPRVTSEEPPRPMSQISGLHGLHHSANLSVATVPRFGVQTDQEEQLAKELEDTKKWGLDVFKVAELSGNHPLTAIIF
SIFQERDLLKTFQIPADTLVTYLLTLEGHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRMSLRRMVIDMVLATDMSKHMNLLADL
KTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHMA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPLDLTTLERGGPDRFQFELTLEEAEEEEEE
EEAVLDREASESPDTELLSPKTSQNPRDLPLDNQRT
>gi|586977370|ref|XP_006928679.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X3 [Felis catus]
MQGPPAPAPAPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGRSTLDPQAGPGLGRVIQAPAQ
HGQRRESFLYRSDSDYDLSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGRGAATQASVENPLFG
SQPPPLTEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQQT
EMELPRVTPTETPRPMSQISGLRGLPHSAGLSAATVPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTTIMF
NIFQERDLLKTFQIPADTLVTYLLTLESHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAAIFASAIHDVD
HPGVSNQFLVNTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADL
KTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLELYRRWTDRIMAEFFQQGDRERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSNLTRSPVDLTRPEQGGPDRFQFELTLEEAEEEEEE
EEEEGPTLDTEVSESPDTELLVPEAGPDPGALPLDSQRPVGKPCVDHEASVMAEPFGT
>gi|301753911|ref|XP_002912850.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like [Ailuropoda melanoleuca]
METPGVQEGAEASSELSRARSRQGTARPPKHLWRQPRRPIRIQQRFYSDPDKSAGCSERDRSPRPGLEKGIMERSSGEAE
PRAPSAPSPLGPAPAAVQKRSRAARAGFSLHAVLAMQGPPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVA
HPLCFDLENGFSCGRSTLDPQAGPGLGRVIQAPAQHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQ
VLASLRTVRSNVAALAHLQGRGAAKVPQGGXGSPXPAWPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFK
RMLNRELTHLSETSRSGNQVSEYISQTFLDQQTEMELPRVTPMETARPMSQISSLRGLPHSASLSAATVPRFGVQTDQEG
QLAKELEDTNKWGLDVFKVAELSENRPLTTIIFSIFQERDLLKTFQIPADTLVTYLLTLESHYHADVAYHNSLHAADVAQ
STHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNIFQ
NLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLELYR
RWTDRIMAEFFQQGDRERESGLEISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKI
PRSPAGPTSPEPGGPDRFHFELTLEEAEEEEEEDGALDTEVSESPDTEPLAPEASSDPGALLPDNQRTGDKPCVDHEANV
MAEPFGT
>gi|545534155|ref|XP_005632755.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Canis lupus familiaris]
MQGPPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLFDLENGLSCGRSTLDPQAGPGLGRVIQASAQH
SQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGRGAAKRSPRGVEAGPX
PARPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQQTEM
ELPRVTPMETPRPMSQISGLRGLPHSASLSAATIPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTTIIFSI
FQERDLLKTFQIPADTLATYLLMLESHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAVFASAIHDVDHP
GVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRQSLRRMVIDMVLATDMSKHMNLLADLKT
MVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLELYRRWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV
EKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVDLTSPQQDSPDRFHFELTLEEAEEEEEEEG
ALDTEVSESPDTELLAPEASLDRGAPLLDNQRTGGKPCVDHEANVMAEPFGT
>gi|602698158|ref|XP_007461108.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Lipotes vexillifer]
MQGPPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSALDPQAGSGLGRVIQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDVIVTPFAQVLASLRTVRSNVAALAHLQGRGAAKQACVGNTPSG
SQPLPPTDDTGQKVALETLEELDWCLDQLETLQARHSVGEMASNKFKWMLNRELTHLSEASSSGNQVSEYISRTFLDQQT
EVELPRVTPTEPPRPMSQISGLRGLPHSTSLSAATVPRFGVQTDQEGQLAKELEDTKKWGLDVFKVAELSGNRPLTAIMF
SIFQERDLLKTFRIPADTLATYLLTLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDTSMLENHHLAVGFKLLQAENCDIFQNLTTKQRLSLRRMVIDMVLATDMSKHMNILADL
KTMVETKKVTSLGVLLLDNYSDHIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVDPTSPKQGGPDRFQFQLTLQEAEEEEGE
EEGALGGEASESPDTELLSPEASPDPGALYLDNQRTVGKPCVNHEGNVMAEPLGT
>gi|466047328|ref|XP_004277598.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Orcinus orca]
MQGPPASAPAPVPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSALDHQAGSGLGRVIQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDVIVTPFAQVLASLRTVRSNVATLAHLQGRGAAKQACVGNTPSG
SQPPPPTEDTGQKLALETLDELDWCLDQLETLQARHSVGEMASNKFKWMLNRELTHLSEASSSGNQVSEYISRTFLDQQT
EVELPRVTPTEPPRPMSQISGLRGLPHSTSLSAATVPRFGVQTDQEGQLAKELEDTKKWGLDVFKVAELSGNRPLTAIMF
SIFQERDLLKTFRIPADTLATYLLTLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDTSMLENHHLAVGFKLLQAENCDIFQNLTTKQRLSLRRMVIDMVLATDMSKHMNILADL
KTMVETKKVTSLGVLLLDNYSDHIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVEPTSPEQGGPDRFQFQLTLQEAEEEEGV
EEGALGGEASESPDTELLSPEASPDPGALYLDNQRTVGKPCVDHEGNVMAEPLGT
>gi|671022716|ref|XP_008702168.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Ursus maritimus]
MQGPPAPAPVPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGFSCGRSTLDPQAGPGLGRVIQAPAQ
HSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGCGAAKQASVENPLIG
TQPPPLTEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKGMLTRELTPLSETSRSGNQVSEYISQTFLDQQT
EMELPRVTPMETPRPMSQISSLRGLPHSASLSAATVPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTTIIF
SIFQERDLLKTFQIPADTLVTYLLTLESHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADL
KTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLELYRRWTDRIMAEFFQQGDRERESGLEISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVGPTSPEPSSPDRFHFELTLEEAEEEEEE
DGALDTEVSESPDTEPLAPEASSDPGALLLDNQRTGDKPCMDHEANVVAEPFGT
>gi|511882250|ref|XP_004828413.1| PREDICTED: LOW QUALITY PROTEIN: phosphodiesterase 4C, cAMP-specific [Mustela putorius furo] >gi|511993372|ref|XP_004828542.1| PREDICTED: LOW QUALITY PROTEIN: phosphodiesterase 4C, cAMP-specific [Mustela putorius furo]
MQGPPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLFDLENGFSCGRSTLDPQAGPGLGRVIQAAAQH
SQRRESFLYRSDSDYELSPKAMSRNSSAASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGRGTVKYGPPGGLVSPX
PAWPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQQTEM
ELPRVTPMESPRPMSQISSLRGLPHRASLSAATVPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTTVMFSI
FQERDLLKTFQIPADTLVTYLLTLESHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHP
GVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKT
MVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLELYRRWTDRIMAEFFQQGDRERESGLDISPMCDKHTASV
EKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVDLTSPEQGSPDRFRFELTLEEAEEEEEEEG
ALDTEVSESPDTELPAPEGSPEPGALLLDNQRTGGKPCVDHEANVMAEPFGT
>gi|472370356|ref|XP_004404690.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Odobenus rosmarus divergens]
MQGPPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGFSCGRSTLDPQAGPGLGRVIQAPAQ
HSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGRGAAKQASVENPLIG
SQPPPPTEDTGQKLALETMDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQQT
EMELPRVTPMETPRPMSQISSLRGVPHSASLSAATIPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTTIIF
SIFQERDLLKRFQIPADTLVTYLLTLENHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADL
KTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLGLYRQWTDRIMAEFFQQGDQERESGLEISPMCDKHTA
SVEKSQVGFIDYIVHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVGLSSPEQVGPDRFHLELTLEEAEEEEEE
GGALDTEVSESPDTELLAPDASADPGALLVDNQRTGGKPCLDHEANVMAEPFGT
>gi|593756267|ref|XP_007116974.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Physeter catodon]
MQGPPATAPAPVPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSALDPQAGCGLGRVIQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDVIVTPFAQVLASLRTVRSNVAALAHLQGRGVARQACVGNTPSG
SQPPPPTEDTGQKLALETLDELDWCLDQLETLQARHSVGEMASNKFKWMLNRELTHLSEASRSGNQVSEYISRTFLDKQT
EVELPRVTPTEPPRPMSQISGLRGLHHSTSLSAATVPRFGVQTDQEGQLAKELEDTKKWGLDVFKVAELSGNRPLTAIMF
SIFQERDLLKTFRIPADTLATYLLTLEGHYHNDVAYHNSLHAADVTQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDTSMLENHHLAVGFKLLQAENCDIFQNLTTKQRLSLRRMVIDMVLATDMSKHMNILADL
KTMVETKKVTSLGVLLLDNYSDHIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVDPTSSKPGGPDRFQFQLTLHEAEEEEGE
EEVALGGEASESPDTELLYPEASPDPGPLYLDSQRTVGKPCVDHEGNVMAETLGT
>gi|426387840|ref|XP_004060370.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Gorilla gorilla gorilla]
MAVRFCHRNESKFENLDEVSMWFWELVDSGLAPVSPLGGGIIRRGFSGTPLLPSLPSRLVPPREVEPSTHVVFTIESFSW
FFSMQRYRGRQTVFGAGVGGVSSAPSFNTPSPRSSPLFYPSAPSGHRQLLGVGPTLSPRSTFYRFSTSGADSSSLSPPLP
ALGRTREXTLLGARSRGRVLLPAIPDPFLWRMENLGVGEGAERCSRLSRSRGRHCMTRAPKHLWRQPRRPIRIQQRFYSD
PDKSAGCRERDLSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYE
LSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPPAEDTGQKLALE
TLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMS
RISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELQDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPAD
TLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTRSWSR
SGYTVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQ
GDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERD
GPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|470652705|ref|XP_004329350.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Tursiops truncatus]
MQGPPASAPAPVPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSSLDHQAGSGLGRVIQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDVIVTPFAQVLASLRTVRSNVATLAHLQGRGAAKQACVGNTPSG
SQPPPPEDTGQKLALETLDELDWCLDQLETLQARHSVGEMASNKFKWMLNRELTHLSEASSSGNQVSEYISRTFLDQQTE
VELPRVTPTEPPRPMSQISGLRGLPHSTSLSAATVPRFGVQTDQEGQLAKELEDTKKWGLDVFKVAELSGNRPLTAIMFS
IFQERDLLKTFRIPADTLATYLLTLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDH
PGVSNQFLINTNSELALMYNDTSMLENHHLAVGFKLLQAENCDIFQNLTTKQRLSLRRMVIDMVLATDMSKHMNILADLK
TMVETKKVTSLGVLLLDNYSDHIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTAS
VEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVEPTSPEQGGPDRFQFQLTLQEAEEEEGEE
EGALGGEASESPDTEFLSSEASPDPGALYLDNQRTVGKPCGDHEGNVMAEALGT
>gi|594068151|ref|XP_006058008.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Bubalus bubalis]
MQGAPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSILDPQAGSGFGQIIQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSMASDLHGEDLIVTPFAQVLASLRTVRSNVAALAGLQDRGAAKQACVCNTPSG
SQPPPPKDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLEQQTE
VELPRATPAETPQPVSQISSLRGLPHSSSLSTATVPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMFS
IFQERDLLKTFQIPADTLATYLLMLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDH
PGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRKMVIDIVLATDMSKHMNLLADLK
TMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTAS
VEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLTLEEAEEEEEAL
DGEASKSPDTELLSSEASPDPGAPHLDYQRTVGKPCTDHEGNAMAEPLGT
>gi|594068149|ref|XP_006058007.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Bubalus bubalis]
MQGAPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSILDPQAGSGFGQIIQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSMASDLHGEDLIVTPFAQVLASLRTVRSNVAALAGLQDRGAAKQACVCNTPSG
SQPPPPKEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLEQQT
EVELPRATPAETPQPVSQISSLRGLPHSSSLSTATVPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMF
SIFQERDLLKTFQIPADTLATYLLMLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRKMVIDIVLATDMSKHMNLLADL
KTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLTLEEAEEEEEA
LDGEASKSPDTELLSSEASPDPGAPHLDYQRTVGKPCTDHEGNAMAEPLGT
>gi|390478729|ref|XP_003735567.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Callithrix jacchus]
MQRXQGRQTVLGXLGGSLSSPWLQHPSPRSSPLFCPSAPSGNRQLLGVGPTLSPGFHLPRFSTSGADSSSLSPALPAXRA
RAQTLLGVRSRGRLLLPAIPDPFLRRMETLGVGEGAEACSRLSRPRGRHGTARAPKHLWRQPRRPIRIQQRFLSDPEKSA
GCREQDLSPRPGLRKSRLSWPISSSRRFDLENGLSSGRSALDPQSSPGLGRVVQAPVHHSQRRESFLYRSDSDYDLSPKA
MSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAVLAHQQCRGAAKQGPVGNLSTSHQPAPPAEDTGQMLALETLDEL
DWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPTVTAEEPPKPVSQISGL
HGLCHSASLSSATVPRFGVQTEQEELLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQRRELLKTFQIPADTLATY
LLLLEGHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAALFASAIHDVDHPGVSNQFLINTNSELALMYND
ASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYPD
RIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWA
DLVHPDAQDLLDTLEDNREWYQSKIPRSPSSLTNPERGGPDKFQFGLPLEEAEEEEEEEEEEGEETALVKEALELSDTEL
PPKSSGVXDSGDLPLDNQRT
>gi|426230294|ref|XP_004009211.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Ovis aries]
MEIQLSEAVQSGLTECQFLEECFLEEAECAKSWSQGDQVHELNIDQCGWKPVRELADSGLAPMSPFGNGVIRTCFSGTPL
LPRLSHCLRTAADMEPRFWRMETPKVQEGLEASRELNSARSRQGVARAPKHLWRQPRRPIRIQQRFHSDPDKSVGRRERD
LSLRPALEKSRRSWPTSFHRRKRLSYAGVELGGGGVMVAYGVCDTVRCTRGPAPVAVQKRSRAASAASSLHAVLAMQGAP
APAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSILDPQAGSGFGRIVQAPAQHSQRR
ESFLYRSDSDYELSSKTMSRNSSMASDLHGEDLIVTPFAQVLASLRTVRSNVAALAHLQDRGAAKQACVCNTPSGSQPPP
PTDTGQKLALETLDELDWCLDQLETLQTQHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLEQQTEVELPR
ATPAEPPRPVSQISSLRALPHSSSLSTATVPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMFSIFQER
DLLKTFQIPADTLATYLLMLESHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGVSN
QFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDIVLATDMSKHMNLLADLKTMVET
KKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTASVEKSQ
VGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLTLEEAEEEEEEEEEALD
GEASKSPDTELRSSEASPDPGASPDPGAPHLDYQRTVGKPCRDHEGNAMAEPLGT
>gi|300797338|ref|NP_001179528.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Bos taurus] >gi|296486089|tpg|DAA28202.1| TPA: phosphodiesterase 4C, cAMP-specific [Bos taurus]
MQGAPAPAPAPGPSSPRGSPRGSPRLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSILDPRAGSGFGQIVQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDLIVTPFAQVLASLRTVRSNVAALARLQDRGAAKQACVCNTPSG
SQPPPPKDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLEQQTE
VELPRATPAEPPRPVSQISSLRGLPHSSSLSTATVPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMFS
IFQERDLLKTFQIPADTLATYLLMLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDH
PGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRKMVIDIVLATDMSKHMNLLADLK
TMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTAS
VEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLPLEEAEEEEEEE
EEALDGEASKSPDTELLSSEASPDPGAPHLDYQRTVGKPCTDHEGNAVAEPLGT
>gi|528954489|ref|XP_005208563.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Bos taurus]
MQGAPAPAPAPGPSSPRGSPRGSPRLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSILDPRAGSGFGQIVQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDLIVTPFAQVLASLRTVRSNVAALARLQDRGAAKQACVCNTPSG
SQPPPPKEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLEQQT
EVELPRATPAEPPRPVSQISSLRGLPHSSSLSTATVPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMF
SIFQERDLLKTFQIPADTLATYLLMLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRKMVIDIVLATDMSKHMNLLADL
KTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLPLEEAEEEEEE
EEEALDGEASKSPDTELLSSEASPDPGAPHLDYQRTVGKPCTDHEGNAVAEPLGT
>gi|560953210|ref|XP_006220495.1| PREDICTED: LOW QUALITY PROTEIN: phosphodiesterase 4C, cAMP-specific [Vicugna pacos]
MQRPPAPAPAPGPSSPRSSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGRSALDPQAGSGLGRVIQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAVLAHLQSRGAAKQGCVGNTPSG
SQPPPPTEDTGQKLALETLDELDWCLDQLETLQTRHSVGELASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQET
EVELSRATSTEPRRPMSQISGLHGLPHSTSLPAATVPRFGVQTDREGQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIF
SIFQERDLLKTFQIPADTLVTYLLMLEGHYHSDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDIVLATDMSKHMNLLADL
KTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIHRSPVDPTSPKQSGPDRFQFQLTLEEAEEEEEE
GALTEEASETPDIEFLSSEASPDPGALHLDNQRTMGKPCMDHEGNMMAEPLGT
>gi|548471593|ref|XP_005682171.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X3 [Capra hircus]
MQGAPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSILDPQAGSGFGRIVQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSMASDLHGEDLIVTPFAQVLASLRTVRSNVAALAHLQDRGAAKQACVCNTPSG
SQHPPPTEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLEHQT
EVELPRATPAEPPRPVSQISSLRALPHSSSLSTATVPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMF
SIFQERDLLKTFQIPADTLATYLLMLESHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDIVLATDMSKHMNLLADL
KTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLTLEEAEEEEEE
EEEALDGEASKSPDTELRSSEASPDPGASPDPGAPHLDYQRTVGKPCRDHEGNAMAEPLGT
>gi|548471589|ref|XP_005682169.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Capra hircus]
MQGAPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSILDPQAGSGFGRIVQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSMASDLHGEDLIVTPFAQVLASLRTVRSNVAALAHLQDRGAAKQACVCNTPSG
SQHPPPTDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLEHQTE
VELPRATPAEPPRPVSQISSLRALPHSSSLSTATVPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMFS
IFQERDLLKTFQIPADTLATYLLMLESHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDH
PGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDIVLATDMSKHMNLLADLK
TMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTAS
VEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLTLEEAEEEEEEE
EEALDGEASKSPDTELRSSEASPDPGASPDPGAPHLDYQRTVGKPCRDHEGNAMAEPLGT
>gi|119605082|gb|EAW84676.1| phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila), isoform CRA_b [Homo sapiens]
MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCR
RFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLA
SLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQL
AKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDAS
VLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRI
QVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADL
VHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLS
PEAGPDPGDLPLDNQRT
>gi|548471591|ref|XP_005682170.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Capra hircus]
MQGAPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLLDLENGLSCGRSILDPQAGSGFGRIVQAPAQH
SQRRESFLYRSDSDYELSSKTMSRNSSMASDLHGEDLIVTPFAQVLASLRTVRSNVAALAHLQDRGAAKQACVCNTPSGS
QHPPPTEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLEHQTE
VELPRATPAEPPRPVSQISSLRALPHSSSLSTATVPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMFS
IFQERDLLKTFQIPADTLATYLLMLESHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDH
PGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDIVLATDMSKHMNLLADLK
TMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTAS
VEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLTLEEAEEEEEEE
EEALDGEASKSPDTELRSSEASPDPGASPDPGAPHLDYQRTVGKPCRDHEGNAMAEPLGT
>gi|555989897|ref|XP_005911970.1| PREDICTED: LOW QUALITY PROTEIN: phosphodiesterase 4C, cAMP-specific [Bos mutus]
MQGAPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQRIRLQRRFTVAHPLCLDLENGLSCGRSILDPQAGSGFGQIVQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDLIVTPFAQVLASLRTVRSNVAALARLQDRGAAKQACVCNTPSG
SQPPPPKDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLDRELXETSRSGNQVSEYISQTFLEQQTEVEL
PRATPAEPPRPVSQISSLRGLPHSSSLSTATIPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMFSIFQ
ERDLLKTFQIPADTLATYLLMLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTASVEK
SQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLPLEEAEEEEEEEEEA
LDGEASKSPGTELLSSEASPDPGAPHLDYQRTVGKPCTDHEGNAVAEPLGT
>gi|585659139|ref|XP_006885946.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Elephantulus edwardii]
MQGSPAPAPGPAPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGRSALDPQGSSGLRAAQTSASH
SQRRESFLYRSDSDYELSPKPMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNMAAFAHLQGCAATNQGRLGTPVASS
ELTPPQDSGQKLALETLEELDWCLDQLETLQTRHSVGEMASNKFKRMLTRELSHLSETSRSGNQVSEYISRTFLDQQTEV
ELPRVTSTEPPWPMSQISGLRELPNSASLSLATVPRFGVQTDQEGQLAKELEDTNKWGLDIFKVAELSGNRPLTAIMFRI
FQERDLLKTFQIPADTFLTYLLTLEGHYHADRAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHP
GVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQTENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKT
MVETKKVASLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDREREIGLDISPMCDKHTASV
EKSQVGFIDYIVHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPPAPSSPQRGGPDRFQFKLTLEEAKEEEEEEE
EQEAMGGEASELPDTELLSPKASPNPQMPQLDSQRTEGRTFMACEGDVMAQPFGT
>gi|556754129|ref|XP_005972435.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Pantholops hodgsonii]
MQGAPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCGRSILDPQAGSGFGRIVQAPAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDLIVTPFAQVLASLRTVRSNVAALAHLQDRGAAKQACVCNTPSG
SQPPPPTEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKLNRELTHLSETSRSGNQVSEYISQTFLEQQTEVEL
PRATPAEPPRPVSQISSLRALPHSSSLSAATIPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMFSIFQ
ERDLFKTFRIPADTLATYLLMLENHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSSKQRLSLRRMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTASVEK
SQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLTLEEAEEEEEEEEEA
LDGEASKSPDTELLSSEASPDPGASPDPGAPHLDYQRTVGKPCMDHEGNAMAEPLGT
>gi|83318161|gb|AAI09069.1| PDE4C protein [Homo sapiens]
TVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNR
ELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKE
LEDTNKWGLDVFKVAELSGNQPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVL
LATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAK
QRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDR
IMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPS
DLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|641728967|ref|XP_008154653.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Eptesicus fuscus]
MQGTPAPAPAAPGPGSPRDSPRSSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENALSRGRSAQDPHIGPGLGQVIQGPA
QHSQRRESFLYRSDSDYELLPKALSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGQRAAKQTSIGNPPS
ASQPPPPTEDTGQKLALETLEELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQQ
TEVELPKGTPKEPSRPMSQISSLQGLPHSASLSTATTPCFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTAII
FSIFQKRDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDV
DHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNIFQNLSTKERLSLRRMVIDIVLATDMSKHMNLLAD
LKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRRWTDRIMAEFFQQGDRERESGLDISPMCDKHT
ASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSPVDPTSPEQGGPDRFQLELTLEEAEEEEE
EERMLAQEASDSPGTDLPSPEASSDPGALCLDNQRTVGKPCMEHEGNTMTPGCLGQVHCTSFSVPKMDFDNFNKSRDLLK
PLSFHG
>gi|594696697|ref|XP_007198688.1| PREDICTED: LOW QUALITY PROTEIN: phosphodiesterase 4C, cAMP-specific [Balaenoptera acutorostrata scammoni]
MQGPPAPAPAPVPSSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCLDLENGLSCRRSALDPQAGSGLGRVIQASAQ
HSQRRESFLYRSDSDYELSSKTMSRNSSVASDLHGEDVIVTPFAQVLASLRTVRSNVASLAHLQGRGAAKRGTGFPSGGG
AGPXPAWPPEDTGQTLALETLDELDWCLDQLETLQARHSVGEMASNKVTXNRELTHLSEAGRSGNQVSEYISQTFLDQQT
EVELPRVTPTEPPSPMSQISGLRGLPHSTSLSAATVPRFGVQTDQEGQLAKELEDTRKWGLDVFKVAELSENRPLTAIMF
SIFQERDLLKTFRIPADTLATYLLTLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDTSMLENHHLAVGFKLLQAENCDIFQNLTIKQRLSLRRMVIDMVLATDMSKHMNILADL
KTMVETKKVTSLGVLLLDNYSDHIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVDPTSPKQGDPDRFQFQLTLQEAEEEEGE
EEGALGGKASESPDTELLSPEASPDPGALYLDNQRTMGKPCVDHEGNVMAEPLGT
>gi|558177213|ref|XP_006100425.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X6 [Myotis lucifugus]
MQGPPAPAPAPGPGSPRDSARSSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENALSRGRSAQDPQVGLGPGQVTQHSQR
RESFLYRSESDYELLPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPP
PPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGDMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVEL
PKGTPKEPSRPMSQISGLQGLPHSASLPTATTPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQ
KRDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEK
SQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSPVDPTSPEQGGLDRFQFELTLEEAEEEEEEEERM
LAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAEPSGS
>gi|586977366|ref|XP_006928677.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Felis catus]
MKTRFDGAFETGRSQRKRASCVSHGESGPALAERWLRAAPHASYKDSTGFDLENGLSCGRSTLDPQAGPGLGRVIQAPAQ
HGQRRESFLYRSDSDYDLSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGRGAATQASVENPLFG
SQPPPLTEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQQT
EMELPRVTPTETPRPMSQISGLRGLPHSAGLSAATVPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTTIMF
NIFQERDLLKTFQIPADTLVTYLLTLESHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAAIFASAIHDVD
HPGVSNQFLVNTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADL
KTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLELYRRWTDRIMAEFFQQGDRERESGLDISPMCDKHTA
SVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSNLTRSPVDLTRPEQGGPDRFQFELTLEEAEEEEEE
EEEEGPTLDTEVSESPDTELLVPEAGPDPGALPLDSQRPVGKPCVDHEASVMAEPFGT
>gi|558177217|ref|XP_006100426.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X7 [Myotis lucifugus]
MQGPPAPAPAPGPGSPRDSARSSPGLFRKLLVNQSIRLQRRFTVAHPLFDLENALSRGRSAQDPQVGLGPGQVTQHSQRR
ESFLYRSESDYELLPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPP
PPEDTGQKLALETLDELDWCLDQLETLQTRHSVGDMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVELP
KGTPKEPSRPMSQISGLQGLPHSASLPTATTPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQK
RDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKS
QVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSPVDPTSPEQGGLDRFQFELTLEEAEEEEEEEERML
AQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAEPSGS
>gi|585190351|ref|XP_006746467.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Leptonychotes weddellii]
METPGVQEGAEASSELSGARSRQGITRPPKHLWRQPRRPIRIQQRFYSDPDKSAGRSERDRSPWPGLEESRRSWPTSYRR
FDLENGFSCGRSTLDPQAGPGLGQVSQAPAQHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLAS
LRTVRSNVAALAHLQRRGAGRRVPQGGXGSPXPAWPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRML
NRELTHLSETSRSGNQVSEYISQTFLDQQTEMELPRVTPMETPRPMSQISSLRGVPHSASLSAATVPRFGVQTDQEGQLA
KELEDTNKWGLDVFKVAELSGNRPLTTIIFSIFQERDLLKTFQIPADTLVTYLLTLESHYHADVAYHNSLHAADVAQSTH
VLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLS
AKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLELYRRWT
DRIMAEFFQQGDQERESGLDISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRS
PVDLTSPEQGGPDRFHFELTLEEAEEEEEEEEGALDTEVSESPDTELLAPEASPDPGALLLDNQRTGGKPCVDHEANVVA
EPFGT
>gi|586520191|ref|XP_006904467.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Pteropus alecto]
MAGSQLPPPLLLLALVLLLKLEGAFSASSDNPTGKNRPPSSTSLTLHWSPTSPGPRMEPSPPPWATTDNTSVDSGRAPGD
TGAPEWHRTPGVVVAVCLLISILLIGSVVMAMRNCHQGVSEFRKLDEVSMRVRESSDSGSAPVSPLGSGVIWRRLSGTPL
LPPLSSRFRPPGETEPSACVVFTIGARKTDQSHGLASGSLQGLARSPKHLWRQPRRPIYIQQRFHSDPDKSAGHSERYWG
PQPGLKKSRRSWPTSFHRRFDLENGLSCGRSALDSQAGPGLGQVIQTSAQYSQRRESFLYRSDSDYELSPKAMSRNSSVA
SDLHGEDMIVTPFAQVLASLRTVRSNVSVLAHLQSGKASKKASVGNAPSGSQPPPSTEDTGQKLALETLDELDWCLDQLE
TLQTRHSVGEMASNKVRRCPLELTHLSETSRSGNQVSEYISRTFLDQQTEVELPRKTPTELPRPMSQISGLRGLPHSASL
STAAVPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNQPLTAIIFSIFQERDLLKTFQIPADTLVTYLLTLEGHYH
ANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHL
AVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLV
HCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQD
LLDTLEDNREWYQSKIPRSPVDPTSPERGGPDRFQFELTLEEAEEEEEEEEEEESILDQRTLESPDTELLSPEARPDPGA
LCLDNHRTVGKPCVDHEGNAMTEPFGT
>gi|281343532|gb|EFB19116.1| hypothetical protein PANDA_000546 [Ailuropoda melanoleuca]
METPGVQEGAEASSELSRARSRQGTARPPKHLWRQPRRPIRIQQRFYSDPDKSAGCSERDRSPRPGLEKTLGSDQAQSAF
SFDLENGFSCGRSTLDPQAGPGLGRVIQAPAQHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLA
SLRTVRSNVAALAHLQGRGAAKQASVENPLIGTQPPPLTEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKR
MLNRELTHLSETSRSGNQVSEYISQTFLDQQTEMELPRVTPMETARPMSQISSLRGLPHSASLSAATVPRFGVQTDQEGQ
LAKELEDTNKWGLDVFKVAELSENRPLTTIIFSIFQERDLLKTFQIPADTLVTYLLTLESHYHADVAYHNSLHAADVAQS
THVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNIFQN
LSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLELYRR
WTDRIMAEFFQQGDRERESGLEISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIP
RSPAGPTSPEPGGPDRFHFELTLEEAEEEEEEDGALDTEVSESPDTEPLAPEASSDPGALLPDNQRT
>gi|562835846|ref|XP_006147230.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Tupaia chinensis]
MAARLQDLAECGERALGLEGGAGTGSALPGLRPLQKADVTKLLGPGSPWIVARHLRVRLEAASSGDAFQGRRPLSNRLGL
PGEAEPSPGVVFTIGARTADKNHSPAPGSTYGVDSSSLSSPPLASGRIGGCRYSWACVHGFSSSSLLSRLPLFWRMETPG
VSEGAEKPRGLSCARSRQGVVRTPKHLWRQPRRPIRIQQRFHSDPNKSASLYERDWSSRPGLGKSRRSWPISFPRRQRGF
SGGLGKGDETSQDGRFGRCGARMFVQERGRQPETGLGNSIRLQRRFTVAHPLCFDLENGLSCGRNTLDPQSGPGLGRGSQ
APGQHSQRRESFLYRSDSDYELSPKAMSRNSSAASDLHGEDLIVTPFAQVLASLRTVRSNVAALAHLQGRGVAKQVSAET
PPSSSSSPPPTEDAGQKLALETLDELDWCLNQLETLQTRHSVGEMASNKFKRMELGIDAPVGLNRELTHLSETSRSGNQV
SEYISRTFLDQPTEMELPRETPPEPPRPLSEISGLRGLPRGPSLSAATVPRFGVQTDQEAQLAKELEDTNRWGLDVFKVA
ELSGNHPLTAVMFSIFRERDLLKTFQIPADTLVTYLLMLEGHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEV
LAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFRNLSAKQRLSLRRMVIDMVLA
TDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERDS
GLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPADLTSPEWSSPDRFQF
ELTLEEAEEEEEEEEEGEEEEASLGQETSESPDTELLSSEASPDPEAPPLGNQRTLGKTCVDREGNMVTESLGT
>gi|591324775|ref|XP_007099374.1| PREDICTED: LOW QUALITY PROTEIN: phosphodiesterase 4C, cAMP-specific [Panthera tigris altaica]
MKTXFDGALETGRSQRKRESCVSPGESGPALAERWLRAAPHASYKDSTSFDLENGLSCGRSTLEPQAGPGLGRVIQAPAQ
HGQRRESFLYRSDSDYDLSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGRGAATQASVENPLFG
SQPPPLTEDPGQKLALETLDELDWCLDQLETLQTRHSVGGMASNKVRRARXLTGKLPPWSAPSRSGNQVSEYISRTFLDQ
QTEMELPRVTPTETPRPMSQISGLRGLPHSAGLSAATVPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTTI
MFNIFQERDLLKTFQIPADTLVTYLLTLESHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHD
VDHPGVSNQFLVNTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLA
DLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLELYRRWTDRIMAEFFQQGDRERESGLDISPMCDKH
TASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVDLTRPEQGGPDRFQFELTLEEAEEEE
EEEEEEGPTLDTEVWESPDTERLVPEASPDPGALPLDNQRPVGKPCVDHEASVMAEPFGT
>gi|634861164|ref|XP_007943660.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Orycteropus afer afer]
MQGSPAPAPGTAPGSPRGSPRSSPGLFRKLLANQSIRLQRRFTVAHPLCFDLENGLSGGRSALASQTSSGLGRAGQTSAT
HSQRRESFLYRSDSDFEFSPKAMSRNSSVASDLHAEDLIVTPFAQVLASLQTVRSNVAAFALLQGRGVGKWTSGGNPPSG
SQPPPPTEDNGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELSHLSETSRSGNQVSEFISRTFLDHET
EVELPSVAPAELSRPMSQISGLRELSPSASLSTATVPRFGIQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTVIMF
SIFQERNLLKTFQIPANTLLTYLLTLEGHYHADAAYHNSLHAADVAQSTHVLLATPALEAVFSDLEILAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQTENCDIFQNLSPKQRLSLRRMVIDMVLATDMSKHMNLLADL
KTMVETKKVASLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDREREIGLDISPMCDKHTA
SVEKSQVGFIDYIVHPLWETWADLVHPDAQGLLDTLEDNREWYQSRIPRSPPAPRSPQRGSLDPVGRFQVELTLEEAEEE
EEEEVQAALCAEALKLAATELPSPKSSLDPQIPQLDNRRTVHKPFMDCEDKVMADFGT
>gi|355766129|gb|EHH62493.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Macaca fascicularis]
MQGPPAPAPAPGPSSPRGSPRGPPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGRRALDPQSSPGLGRVMQAPVP
HTQRRESFLYRSDSDYELSPKAVSRNSSVASDLHGEDMIVTPFAQVKYLFLPSPAEDSWELPFRKDTGQKLALETLDELD
WCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLH
GLCHGASLSSATVPRFGVQTDQEEQLAKTKALRPGSVMDQERDLLKTFQIPADTLATYLLMLEGHYHADVAYHNSLHAAD
VAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAKNCD
IFQNLSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLP
LYRQWTDRIMAEFFHQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQ
SKIPRSPSDLTNPEWGGPDRFQFELTLEEAEEEDEEEEEDGKREL
>gi|403303576|ref|XP_003942402.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Saimiri boliviensis boliviensis]
MTGFESFWVIVFRRSGVQVKRAGTAPRGSRSAQERLHTLRSPTYASPLHSAVLRQQGAHMQVPGAGTWAHTWPHAGAELA
AGPPGAGMAGPQLPRLLFVLLVPVLLLKASDVSDTTPHTGFGGMGHRADSEPLLPAPGDTGPPELHRDPGVVVIVCLLVS
LLVIGSVVLAVRFCHRDKSKFGRLDEVSMGSVNDRSAFAYHLQEAGPALPGACKPHKRLRRSRDVCSMRRSATALSFRLS
EVLGLVDFGLAPVSPNGGGIIRRGFSGPPLLPPLPSRLGLPGEVEPSARVVFTIEAQGTERRHSVVPGRAPKRPLLGLNR
GAYLLGLAERPLSSLSWFFSTQRXRGRQAVLGAGXGVSPAPSFNXPSPRSSPLFCPSAPSGNRQLLGFGPTLSPGFHLPR
FSTSGADSSSLSPALPALGRTRAQTLLGARSRGRLLLPAIPDSFLWRMETLGFGEGAEACSRLSRPRGRHGTARAPKHLW
RQPRRPIRIQQRFHSDPDKSAGCREQDLSPRPGIRKSRLSWPISSCRRFDLENGLSSGRSALDPQSSPGLGRVVQAPVHH
SQRRESFLYRSDSDYDLSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAVLAHQQCRGAAKQGPVGNLSSSH
QPPPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISQTFLDQQTE
VELPTVTAEEPPKPVSQISGLHGLCQNASLSSATVPRFGVQTEQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFS
IFQERDLLKTFQIPADTLATYLLLLEGHYHADVAYHNSLHAADVAQSTHVLLATPALEXXXXSELALMYNDASVLENHHL
AVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYPDRIQVLQSLV
HCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQD
LLGTLEDNREWYQSKIPRSPSSLTNPEQGGPDRFQFGLPLEEAEEEEEEGEEPALDKEALELSDTELPPEASPDPGDLPL
DNQRT
>gi|585659135|ref|XP_006885945.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Elephantulus edwardii]
MRRSGTAHSFLLCERIRESAESASAPVSPLGSGVIRRRFSGTPLLPPLPSRLGPTGEVESSARVVFTIEARGPERSYGPT
PGSFDLENGLSCGRSALDPQGSSGLRAAQTSASHSQRRESFLYRSDSDYELSPKPMSRNSSVASDLHGEDMIVTPFAQVL
ASLRTVRSNMAAFAHLQGCAATNQGRLGTPVASSELTPPQDSGQKLALETLEELDWCLDQLETLQTRHSVGEMASNKFKR
MLTRELSHLSETSRSGNQVSEYISRTFLDQQTEVELPRVTSTEPPWPMSQISGLRELPNSASLSLATVPRFGVQTDQEGQ
LAKELEDTNKWGLDIFKVAELSGNRPLTAIMFRIFQERDLLKTFQIPADTFLTYLLTLEGHYHADRAYHNSLHAADVAQS
THVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQTENCDIFQN
LSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVASLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQ
WTDRIMAEFFQQGDREREIGLDISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIP
RSPPAPSSPQRGGPDRFQFKLTLEEAKEEEEEEEEQEAMGGEASELPDTELLSPKASPNPQMPQLDSQRTEGRTFMACEG
DVMAQPFGT
>gi|554559058|ref|XP_005873927.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X4 [Myotis brandtii]
METPGVPEGARAPSELNRALGGQGLARSPKHLWRQPRRPIRIQQRFHSDPDKSAGRSQQNRGPRLGLQKSRCSWPTSFHR
CFDLENALSRGRSAQDPQVGPGPGQVTQHSQRRESFLYRSESDYELLPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRT
VRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLTR
ELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGLPHSASLSTATIPCFGVQTDQEAQLAKE
LEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNSLHAADVAQSTHVL
LAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNVFQNLSTK
EWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDR
IMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSPG
DPTSPEQGGLDRFQFELTLEEAEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAEPS
GS
>gi|554559056|ref|XP_005873926.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X3 [Myotis brandtii]
MRRSGTALSFLLSEVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPPGETEPSSCVVFTIGAQGTEQSHGPAS
SSFDLENALSRGRSAQDPQVGPGPGQVTQHSQRRESFLYRSESDYELLPKAMSRNSSVASDLHGEDMIVTPFAQVLASLR
TVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLT
RELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGLPHSASLSTATIPCFGVQTDQEAQLAK
ELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNSLHAADVAQSTHV
LLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNVFQNLST
KEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTD
RIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSP
GDPTSPEQGGLDRFQFELTLEEAEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAEP
SGS
>gi|554559052|ref|XP_005873925.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Myotis brandtii] >gi|554559054|ref|XP_005873931.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X8 [Myotis brandtii]
MRRSGTALSFLLSEQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPPGETEPSSCVVFTIGAQGTEQSHGPA
SSSFDLENALSRGRSAQDPQVGPGPGQVTQHSQRRESFLYRSESDYELLPKAMSRNSSVASDLHGEDMIVTPFAQVLASL
RTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRML
TRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGLPHSASLSTATIPCFGVQTDQEAQLA
KELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNSLHAADVAQSTH
VLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNVFQNLS
TKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWT
DRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRS
PGDPTSPEQGGLDRFQFELTLEEAEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAE
PSGS
>gi|344283093|ref|XP_003413307.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Loxodonta africana]
METPGVGEGAEASTGLSSARSRQGTARPPKHLWRQPRRPISIQQRFHSDPDKSVRRSGLEKSRRSWPNSFPRRFDLENGL
SCGRSALDTQASSGLGRASQTSAPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSN
VAAFAHLQGRGAAKYAEGGARRRGRDRSVRGKVPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRE
LSHLSETSRSGNQVSEYIFQTFLDQQTEVELPRVTPVETPRPMSQISGLRELPHSASLSTASVPRFGIQTDQEEQLAKEL
EDTNKWGLDVFRVAELSRNQPLTVIMFSIFQERDLLKTFRIPAGTLITYLLTLESHYHADVAYHNSLHAADVAQSTHVLL
ATPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLALGFKLLQTENCDIFQNLSAKQ
RLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVASLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRI
MAEFFQQGDRERETGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQGLLDTLEDNRAWYQSRIPCSPLA
PRSPQRGGPDRFQFELTLEEEEEEEEGEPVALDREASELPDIELLSPKTSPDPQIPQLDNQRTVGKPLTDCEGNVMAKPF
GT
>gi|554559050|ref|XP_005873924.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Myotis brandtii]
MAGHRTPQCQACLGLTGLVFRDACSMRRSGTALSFLLSEQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPP
GETEPSSCVVFTIGAQGTEQSHGPASSSFDLENALSRGRSAQDPQVGPGPGQVTQHSQRRESFLYRSESDYELLPKAMSR
NSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWC
LDQLETLQTRHSVGEMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGL
PHSASLSTATIPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLT
LEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASV
LENHHLAVGFKLLQAENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQ
VLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLV
HPDAQDLLDTLEDNREWYLSKIPRSPGDPTSPEQGGLDRFQFELTLEEAEEEEEEERMLAQEASESPDTDLLSPEASSDP
GALCLDNQRTVGKPCMDHEGNVTAEPSGS
>gi|528768832|gb|EPY88491.1| cAMP-specific 3,5-cyclic phosphodiesterase 4C-like protein [Camelus ferus]
METPGVQEGVEASRELNRARSRQGIVKPPKHLWRQPQRPICIQQRFHSDPDKSVGCRERDRSPRPGLEKSQLSWPTSFHR
RGGVPERSNGGEAGLKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGRSALDPQAGSGLGRVIQAPAQHSQRRESFLYRSD
SDYELSSKTMSRNSSVASDLHGEDMIVTPFAQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSET
SRSGNQVSEYISRTFLDQETEVELSRATSTEPRRPMSQISGLRGLPHSTSLPAATVPRFGVQTDREGQLAKELEDTNKWG
LDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLVTYLLMLEGHYHSDVAYHNSLHAADVAQSTHVLLATPALEA
VFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSIKQRLSLRRM
VIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQ
GDRERESGLDISPMCDKHTASVEKSQVGFIDYITHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIHCSPVDPTSPKQS
GPDRFQFQLTLEEAEEEEEEEEGALIEEASETPDIELLSSEASPDPGALHLDNQRTMGKPCMDHEGNMMAEPLGT
>gi|584039744|ref|XP_006778469.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Myotis davidii]
MADTDALQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPPGETEPSSSVVFTIGARGTEQSHGPASSSFDLE
NALSRGRSAQDPQVGPGPGQVTQHSQRRESFLYRSESDYELLPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNV
AALAHLQGQRAAKQTSIGNPPSGCQPPPPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLTRELTHL
SETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGLPHSASLSTATIPCFGVQADQEGQLAKELEDTN
KWGLDVFKVAELSANRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLTLEGHYHADMAYHNSLHAADVAQSTHVLLAMPA
LEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNVFRNLSAKEWLSL
RRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEF
FQQGDREREAGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSPVDPTSP
EQGGLDRFQFELTLEEAEEEEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAEPSGS
>gi|558177200|ref|XP_006100422.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X3 [Myotis lucifugus]
MRRSGTALSFLLSEVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPPGETEPSSCVVFTIGARGTEQSHGPAS
SSFDLENALSRGRSAQDPQVGLGPGQVTQHSQRRESFLYRSESDYELLPKAMSRNSSVASDLHGEDMIVTPFAQVLASLR
TVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGDMASNKFKRMLT
RELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGLPHSASLPTATTPCFGVQTDQEAQLAK
ELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNSLHAADVAQSTHV
LLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNVFQNLST
KEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTD
RIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSP
VDPTSPEQGGLDRFQFELTLEEAEEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAE
PSGS
>gi|558177192|ref|XP_006100420.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Myotis lucifugus]
MAGHRTPQCQACLGLTEPVFRDACSMRRSGTALSFLLSEQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPP
GETEPSSCVVFTIGARGTEQSHGPASSSFDLENALSRGRSAQDPQVGLGPGQVTQHSQRRESFLYRSESDYELLPKAMSR
NSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWC
LDQLETLQTRHSVGDMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGL
PHSASLPTATTPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLT
LEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASV
LENHHLAVGFKLLQAENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQ
VLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLV
HPDAQDLLDTLEDNREWYLSKIPRSPVDPTSPEQGGLDRFQFELTLEEAEEEEEEEERMLAQEASESPDTDLLSPEASSD
PGALCLDNQRTVGKPCMDHEGNVTAEPSGS
>gi|558177209|ref|XP_006100424.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X5 [Myotis lucifugus]
METPGVPEGARAPSELNRALGGQGLARSPKHLWRQPRRPIRIQQRFHSDPDKSAGRSQQNRGPRLGLQKSRCSCPTSFHG
FDLENALSRGRSAQDPQVGLGPGQVTQHSQRRESFLYRSESDYELLPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTV
RSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGDMASNKFKRMLTRE
LTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGLPHSASLPTATTPCFGVQTDQEAQLAKEL
EDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNSLHAADVAQSTHVLL
AMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCNVFQNLSTKE
WLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRI
MAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSPVD
PTSPEQGGLDRFQFELTLEEAEEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAEPS
GS
>gi|558177196|ref|XP_006100421.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Myotis lucifugus]
MRCPWFRDACSMRRSGTALSFLLSEQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPPGETEPSSCVVFTIG
ARGTEQSHGPASSSFDLENALSRGRSAQDPQVGLGPGQVTQHSQRRESFLYRSESDYELLPKAMSRNSSVASDLHGEDMI
VTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWCLDQLETLQTRHSVG
DMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGLPHSASLPTATTPCF
GVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNS
LHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQ
AENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNP
TKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDN
REWYLSKIPRSPVDPTSPEQGGLDRFQFELTLEEAEEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGK
PCMDHEGNVTAEPSGS
>gi|586491876|ref|XP_006876393.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Chrysochloris asiatica]
METLGVSEGAETYCSYSRSRQGIARPPKHLWRQPRHPIRIQQRFHSDPDKCAHHAESDGSPRPGLKKARRSWPTSFHRRF
DLENGLSCGRSALDPPASAGLGRASQTSALHSQRRESFLYRSDSDYELSPKPMSRNSSVASDLHGEDMIVTPFAQVLASL
RTVRSNVASFTNLQGRWTAKWASGGNPASGSQLPPPTEDTGQKLALETLDELDWCLDQLETLQTQHSVGEMASNKFKRML
NRELSHLSETSRSGNQVSEYISRTFLDQQTVVELPRVTPTDRPQPMSQISGLRELPHNVSLSAATVPRFGVQTDQEGQLA
KELEDTNKWGLDVFKVAELSGNQPLTAIMFSIFRERDLLKTFQIPADTFVTYLLTLEGHYHADVAYHNSLHAADVVQSTH
VLLATPALEAVFTDMEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDVSVLENHHLAVGFKLLQTENCDIFQNLS
AKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVASLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWT
DRIMAEFFQQGDRERDIGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRS
PLAPSSPQRGGLDRFQFELTLEEAEEEEEEEQATLEGETSEIPDTELNPKTSLHLQLPQLDNQRTVGNPFVNSEDNTMAD
SFGT
>gi|564388510|ref|XP_006252931.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Rattus norvegicus]
MQGSTAPGSPRGSPRGSPALFRKLLVNQSIRLQRRFTVAHPLCFDLENGLPSGRGPLDAQSGSSLGRALQPPVHHGQRRE
SFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGSATRQALLGTPPQSSQQAAPA
EESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQQAEVELPAP
PTEDHPWPMAQITGLRKSCHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGFDVFKVAELSGNRPLTAVIFSVLQERDL
LKTFQIPADTLLRYLLTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQF
LINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKK
VTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVG
FIDYIAHPLWETWADLVHPDAQELLDTLEDNREWYQSRVPCSPPHAIGPDRFKFELTLEETEEEEEEDERH
>gi|521030669|gb|EPQ12455.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Myotis brandtii]
METPGVPEGARAPSELNRALGGQGLARSPKHLWRQPRRPIRIQQRFHSDPDKSAGRSQQNRGPRLGLQKSSFDLENALSR
GRSAQDPQVGPGPGQVTQHSQRRESFLYRSESDYELLPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAH
LQGHRAAKILMAQPPEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRMLTRELTHLSETSRSGNQVSEYIS
QTFLDQQTEVELPKGTPKEPSRPMSQISGLQGLPHSASLSTATIPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGN
RPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLTLEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEVRSYGQAGQVQGA
VQRARRSALMPMPAQAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCN
VFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLP
LYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYL
SKIPRSPGDPTSPEQGGLDRFQFELTLEEAEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHE
GNVTAEPSGS
>gi|612011956|ref|XP_007489292.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Monodelphis domestica]
MLGGQHSPPGPGPGTPSSPVGSPRASPRSSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSSGRSPLDPQTSPGSGL
VIQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNFAVLTRLQDRVAKRVSG
SNPTSGCRAPPLPEDACQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISRT
FLDKQHEVELPSMPVKEREKEKEERPMSQISGVRKLTHGSSFSAAAIPRFGVKTDHETLLAKELKDTNKWGLDVFKVAEL
SGNRPLTAIMYSIFQERDLLKTFRIPVDTLVTYLLTLEDHYHADVAYHNSIHAADVAQSTHVLLSTPALEAVFTDLEILA
AIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEDNCDIFQNLRPKQRQSLRKMVIDMVLATD
MSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFQQGDREREKGI
EISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPDGGHEAGPAKGGGAADKF
QFELTLEEEEGESDSEAEEPGSRAEEGEEENSGSDSKTLATDDSESAEVEPLSPEEEASPVEEHRPQASVALDNERTLSQ
AEAKSLQEGDGAVDQEGNLTFYPLGT
>gi|505846868|ref|XP_004616906.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Sorex araneus]
MRRSGTALPFLLSEVRELTDSASAPVSPQGTRIIRRRFSGTPLLPPLSSRLGSPGADTEPSTRVVFTIETRGAEPSQGPA
LGSFDLENGFSCGRSSLDPQVGPGLGRAVQAPSQHCQRRESFLYRSDSDFELSPKAMSRNSSVASDLHGEDMIVTPFAQV
LASLRTVRSNVTALAHLPSRGAARQASVGNPLTTAQPPAPSEEPGHKLAWETLEELDWCLEQLESLQTQHSVGEMASNKF
KRMLSRELTHLSETSRSGNQVSEYIARTFLDQKTEMDLPLVAQAESSRPMSQISVLRRSPHQASFSAAAVPRFGVQTDQE
EQLAKVLEGVHKWGLDVFKVAELSGGRPLTAVIFSIFQGRDLLKTFQIPPDTLVTYLLTLESHYRQDVAYHNSTHAADVA
QSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIF
QNFSAKQRLTLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLMLDHYSDRIQVLQSLVHCADLSNPTKPLELY
RQWTARIMAEFFQQGDRERDAGLDVSPMCDKHSASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSK
IPRSPMDTSSPEHGGPDRFQFELTLEEAEEEEEEGEEEGKEGTSNLESLGSPSCQLLSPEASPDPETLLLNTPRTTGHAC
VDVGDGGTAPPCDS
>gi|586977368|ref|XP_006928678.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Felis catus]
MSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGRGAATQASVENPLFGSQPPPLTEDTGQKLALETLDEL
DWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQQTEMELPRVTPTETPRPMSQISGL
RGLPHSAGLSAATVPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTTIMFNIFQERDLLKTFQIPADTLVTY
LLTLESHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLVNTNSELALMYND
ASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSD
RIQVLQNLVHCADLSNPTKPLELYRRWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWA
DLVHPDAQDLLDTLEDNREWYQSNLTRSPVDLTRPEQGGPDRFQFELTLEEAEEEEEEEEEEGPTLDTEVSESPDTELLV
PEAGPDPGALPLDSQRPVGKPCVDHEASVMAEPFGT
>gi|533193717|ref|XP_005409620.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Chinchilla lanigera]
MAGSRRLPLLIIALALLLKSSGSEDSPSTAAVSSVQTETKALSATPEISSSSDPGSSSPGGTSIPQSGSPSTEEVSTAQS
SPAPAGSGTASGSPEPHPTTVTHAGSESPSSELTPASDSAPPIPPRTPSSSMPVQGATQTRTSHRNPGVVVAVCVLVSVV
IIGSVLLVVRGRHRDTSEFLVLDEVCLVSPARMRRSGTALSFLLSERVQEPLDSGSAPVSPHGGGVVRRQFSGSLLLPPL
WSRPGPPGEAEPSARVVFTIGARGTERSQASAPGRKLLVNQSIRLQRRFTVAHPLCFDLDNGPSCGRGTQAPGSHSQRRE
SFLYRSDSDYELSPKAMSRNSSAGSDLHGEDLIVTPFAQVLASLRTVRSNVAALAQGPCGAARPASVGSPPVGSQSPAAA
EDAGPPLALETLAELDWCLDQLEALHTRHSVGDMASTKFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQHADVELPTR
PLSEIPGLGGLPRPGRSLATVPRFGVETDREGQLAKELEDTNKWGLDVFRVAELSGNRPLTAILFSIFQERDLLKTFQIP
ADTLATYLLTLEGHYHSNVAYHNSLHAADVAQSAHVLLATPALQAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTKSE
LALMYNDISVLENHHLAVGFKLLQAENCDIFRNLSAKQWLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVL
LLDTYADRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDQERESGLDISPMCDKHTASVEKSQVGFIDYIAH
PLWETWADLVHPDAQDLLDTLEDNRSWYHSRVPRSPLDPVGSERGAPDRFQFELTLEEAEEEEVAAAGSPCT
>gi|564264537|ref|XP_006271115.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Alligator mississippiensis]
MLNLRRGSPGASPGTSPRNSPRNSPVLFRKLLMNQSIRLQRRFTVAHPLCFDIENGLASARSPLDPQASPSAGLVLQGPF
PHSQRRESFLYRSDSDYDLSPKSMSRNPSIASDLHGEDMIVTPFAQVLASLRTVRSNVAALTHLQDRVTNKRTTSNSPAP
TCKPSLSEDAYQKLAVETLEELDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDNQH
EVEIPSPPPKEDKEKAQRPMSQISGVKKLMHSSSLSSASIPRFGVKTDQEGPLAKELEDANKWGLDMFKVAEYSGNRPLT
VIMYTIFQERDLMKTFRIPPDTFITYMMTLEDHYHADVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAI
HDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMAIDMVLATDMSKHMNL
LADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEISPMCD
KHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPPPEAPEPSPDKFELELTLAEDGE
SEPEEAESPLEEDTSGSDSKTLPMDDSESTETELLSASSAGQDSPPPGHGSPHRSAPARQEQALNFDHQGPGLRTLSPPE
GSAPPEPGRGGSQGDREMNLDSEGNVTFLPLGT
>gi|560896818|ref|XP_006174875.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Camelus ferus]
MSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAVLAHLQGRGAGKQGCVGNTPSGSQPPPPTEDTGQKLALETLDEL
DWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQETEVELSRATSTEPRRPMSQISGL
RGLPHSTSLPAATVPRFGVQTDREGQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLVTY
LLMLEGHYHSDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYND
ASVLENHHLAVGFKLLQAENCDIFQNLSIKQRLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSD
RIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYITHPLWETWA
DLVHPDAQDLLDTLEDNREWYQSKIHCSPVDPTSPKQSGPDRFQFQLTLEEAEEEEEEEEGALIEEASETPDIELLSSEA
SPDPGALHLDNQRTMGKPCMDHEGNMMAEPLGT
>gi|528954491|ref|XP_005208564.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Bos taurus]
MSRNSSVASDLHGEDLIVTPFAQVLASLRTVRSNVAALARLQDRGAAKQACVCNTPSGSQPPPPKDTGQKLALETLDELD
WCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLEQQTEVELPRATPAEPPRPVSQISSLR
GLPHSSSLSTATVPRFGVQTDQEGQLAKELEDTSKWGLDVFKVAELSGNRPLTAIMFSIFQERDLLKTFQIPADTLATYL
LMLEGHYHNDVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDA
SVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDR
IQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDSERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWAD
LVHPDAQDLLDTLEDNREWYQSKIPRSPEDPTSPKQGSPDRFQFQLPLEEAEEEEEEEEEALDGEASKSPDTELLSSEAS
PDPGAPHLDYQRTVGKPCTDHEGNAVAEPLGT
>gi|530564989|ref|XP_005279065.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X4 [Chrysemys picta bellii]
MMNQSIRMQRRFTVAHPLCFDIENGLSSGRSPLDPQASPGSGLVLQGNVPHSQRRESFLYRSDSDYDLSPKAMSRNSSIA
SDLHGEDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVASKRTSSSNPPSVCKASLSEDACQKLAIETLEELDWCLDQLET
LQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDKQHEVEIPSPTPKEKEAEKTTRPMAQISGLKKLT
HSSSFISSSIPRFGVKTDQEGLLAKELKDTNKWGLDMFKITEYSGNRPLTVVMYSIFQERDLMKTFSIPADTFITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEVMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDVSVL
ENHHLAVGFKLLQEENCDIFQHLSKKQRQSLRKMAIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEISPMCDKLSASVEKSQVGFIDYIAHPLWETWADLVH
PDAQEILDTLEDNREWYQSMIPRSPSPPEEQDPEKGGGGEKFQFQLTLEEEGESDTEPEEAESPLEEDNSGSDSKMLATD
DSESPELERLSPGSAGRDSPPPTPSGPLRNTLVKQKEALHFDNRRALERTLSQPDGGTSELGRRGSLEAKELALDTEGNL
TFLPLGT
>gi|512814526|ref|XP_002934844.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Xenopus (Silurana) tropicalis]
MQMPTLSASPPHRSPGRQSPRDSPRTSPRGSPLSSPRNSPLLLRKLLMSRNSRMQRRFTVAHPPCFDVENGLSSGRSPLE
SQASPGSGLVLQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTVRSNFAMLTHLQ
DRVSNKRSSGSNQPSACKPNLSEDAVQKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGN
QVSEYISSTFLDKQHEVEIPTPVSKEKDKKKRPMSQISGVKKLTHSSSFSNCSIPRFGVKTEQEVPLAKEVENINKWGLD
IFKVAEYSGNRPLTVIMYSIFQERDLLKTFHIPVDTFITYMMTLEDHYHSDVAYHNNIHAADVAQSTHVLLSTPALEAVF
TDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLTKKQRQTLRKMVI
DMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIIVEFFHQGD
REREKGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPQSPSPPPEEQDPDR
GNAAGDKFQFELTLEEEGESDTEQEDTESPIDEENSDSKIHATDDSAQASDEAEQSSPVDLCMTVSSKLDHLEIPPKSTL
TKQKKILNFDNLKLAGERTIQQKEVSSSHATPANSARQEGTGQAEICLDQEGNITYLPLGT
>gi|545198939|ref|XP_005604176.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Equus caballus]
MIVTPFAQVLASLRTVRSNVAALAHLQGRGATKQAPVGKPPSGSQAPPSTEDPGQKLALETLDELDWCLDQLETLQTRHS
VGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPRVTPTEPPKPISQISGLRGLPHSASLSAATFP
RFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLVTYLLTLEGHYRADVAYH
NSLHAADVAQSTHVLLATPALQAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKL
LQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVASLGVLLLDNYSDRIQVLQNLVHCADLS
NPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDVSPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLE
DNREWYQSKVPRSPMDPTSPEQGSPDRFQFELTLDEAEEEKEAEEEGALDGEASESPDTELLSPEASLDPGGLLLDNQRT
AGKPCKNHEGGVMAEPFGN
>gi|554526272|ref|XP_005857978.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Myotis brandtii]
MAQQAASPDTLAVPEVDNPHCANPWLNEDLVKSLRENLLQNEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLNSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEVPLDEQ
VEEEAVGDEEESQPEACVIDDHSPDT
>gi|641695223|ref|XP_008160061.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Eptesicus fuscus]
MAQQTASPDTLAVPEVDNPHCANPWLNEDLVKSLRENLLQNEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLNSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEEVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEEESQPEACVIDDHSPDT
>gi|584085522|ref|XP_006762499.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Myotis davidii]
MAQQAASPDTLAVPEVDNPHCANPWLNEDLVKSLRENLLQNEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLNSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRPGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEVPLDEQ
VEEEAVGDEEESQPEACVIDDHSPDT
>gi|513229248|ref|XP_003643033.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Gallus gallus]
MAQQTSPDTLAVPEVDNSPCQNPWLNEDLVKTLRENLLQYEKSGTSKKSSSASPRLSPVISPRNSPRLLRRMLLNSNIPK
QRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
VTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTVFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVGEEVEEEENQTESCVVDHSPDT
>gi|507615280|ref|XP_004623127.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Octodon degus]
MAQQASPDTLAVPEVDNPHGPNPGLNEDLVKSLRENLLQHEKSKRTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDPEEGPQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGGGESQPEVCVTDECSPDT
>gi|542162316|ref|XP_005489825.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Zonotrichia albicollis]
MAQQTSPDNLPVPEGDNTHSQNPWLNEDLVKTLRENLLQHEKSRTTRKSSPAPPRLCPVISPRNSPRLLRRMFLNSNIPK
QRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
VTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITEEAYQKLASETMEELDWCLDQLETLQTRHSVSE
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDE
QVGEEVEEEENQTAESCVVEEHSPDT
>gi|525026525|ref|XP_005060708.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Ficedula albicollis]
MAQQTSPENLPVPEVDNTQSQNPWLNEDLVKTLRENLLQREKSRTTQKSSPASSRLCPVISPRNSPRLLRRMFLNSNIPK
QRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
VTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITEEAYQKLASETMEELDWCLDQLETLQTRHSVSE
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDE
QVGEEVEEEENQTAEPCMVEEHSPDT
>gi|556960540|ref|XP_005990763.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Latimeria chalumnae]
MAQQATCPDTLSVPEVESVPCKSTALNEDLVKTLRENLLKYEKPRKPRKSPSISPRLSPTISPRNSPRLLRRMMLNSSIQ
KQRRFTVAHTCFDVDNGTSSGRSPLDPLASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATFTEEAYQKLATETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPAQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEEEDSLSKELEEVNKWGLNVFKVAEYSGNRPLTVVMYTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVAQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTNRVMEEFFRQGDRERERGMEISPMCDKHNASIEKTQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDEQEEGRPGQSEKFQFELTLEEDGESDTEKDSGSQVEEDNSFSDSKTLCTQDSESTEIPLD
EQGEEEEAPTEVCIEEDQTTDT
>gi|545199144|ref|XP_005604250.1| PREDICTED: phosphodiesterase 4D, cAMP-specific isoform X1 [Equus caballus] >gi|664711477|ref|XP_008512714.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Equus przewalskii]
MAQQTTSPDTLTVPEVDNPRCPNAWLNEDLVKSLRENLLQHEKSKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEEESQPEACAAEDRSPDT
>gi|507934226|ref|XP_004678346.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Condylura cristata]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRASSKRSPMCNQPSINKTTITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGHTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEESQPEACVIEDRSPDT
>gi|670997467|ref|XP_008689614.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Ursus maritimus]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQQEKSKPARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEETVGEEEESQPEACVVEDHSPDT
>gi|345794106|ref|XP_003433851.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX2 [Canis lupus familiaris]
MAQQTTSPDTLTVPDVDNPHCPNPWLNEDLVKSLRENLLQQEKSKPARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEETVGEEENSQPEACVIEDHSPDT
>gi|586491548|ref|XP_006876229.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Chrysochloris asiatica]
MAQPTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEEESQPEACVIEDHSPDT
>gi|585679881|ref|XP_006891577.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Elephantulus edwardii]
MAQQTASPDTLAVPEVDNPHCPNPWLNEDLVKSLRENLLQQEKSKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEDAVGEAEESQPEVCIIEDHSPDT
>gi|585151180|ref|XP_006728028.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Leptonychotes weddellii]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQQEKSKPARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEETVGEEEDSQPEACVIEDHSPDT
>gi|472378756|ref|XP_004408796.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 3 [Odobenus rosmarus divergens]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQQEKSKPARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEETVGEEEDSQPAACVIEDHSPDT
>gi|358417738|ref|XP_003583732.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Bos taurus] >gi|359077383|ref|XP_003587560.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX4 [Bos taurus] >gi|555953882|ref|XP_005889110.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Bos mutus]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVADEESQPEACVIGDPSPDT
>gi|511840327|ref|XP_004744668.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Mustela putorius furo] >gi|511942072|ref|XP_004789810.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Mustela putorius furo]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQQEKSKPARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEETVGEEEDSQPEPCGIEDHSPDT
>gi|327262964|ref|XP_003216292.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Anolis carolinensis]
MAQQTASPDTLAVPEVDNSHCQNAWLNEDLVKTLRENLLQHEKPKASRKSSPVSPKVSPVISPRNSPRLLRRMLLSSNIP
KQRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PKFGVKTDQEDILAKELEDVNKWGLQVFKIAEFSGNRPLTVIMYTIFQERELLKTFKIQPDMLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTDKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVGGEVEEEEEEEQSQTEHCVQEEHSPDT
>gi|504142678|ref|XP_004583775.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Ochotona princeps]
MAQPTTSPDTLAVPKVDNPHGPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSTGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDPEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
AEEEAVAEEESQPEACVIDDCSPDT
>gi|334325194|ref|XP_001381247.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Monodelphis domestica]
MAQQTSSPDTLTVPEADNPHCANPWLNEDLVKSLKENLLQHEKSKVSRKSVSPKLSPVISPRNSPRLLRRMLLNSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSPVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEEEEEDPAEPCAIENEHSPDT
>gi|655839233|ref|XP_008260467.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Oryctolagus cuniculus]
MAQHTTSPDTLAVPEVDNPHGPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEESQPEACVIDDYSPDT
>gi|80478887|gb|AAI09068.1| PDE4C protein [Homo sapiens]
MASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFG
VQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSL
HAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQA
ENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPT
KPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNR
EWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQR
T
>gi|591357842|ref|XP_007053941.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Chelonia mydas]
MAQQTTSPDTLTVPEVDNPQCQNPWLNEDLVKNLRENLLQNEKSKTSRKSSSVSPRFSPVTSPRNSPRLLRRMLLNSNIP
KQRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVIMHTIFQERDLLKTFKIPADTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLD
EQVGEEVEGEESHTEPCVLEEDHSPDT
>gi|556740070|ref|XP_005965583.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Pantholops hodgsonii]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEATETPLDEQ
VEEEAVAGGEGAQPEACVAGEPSPGT
>gi|541952633|ref|XP_005432777.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Falco cherrug]
MAQQTSPGTLAVPEVDNKHCQNPWLNEDLVKTLRENLLQHEKSRTSRKSSSASPRLCPVISPRNSPRLLRRMLLNSNIPK
QRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
VTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMYTIFQERDLLKIFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDGQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVGEEVEEEENHTEPCVVEDHSPHT
>gi|471392341|ref|XP_004380550.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Trichechus manatus latirostris]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEEERQPEACVIEDHSPDDT
>gi|344272310|ref|XP_003407976.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Loxodonta africana]
MAQQTTNPDTLAVPEADNPHCPNPWLNEDLVKTLRENLLQHEKSKTATKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEEESQPEACVIEDHSSDDT
>gi|594655499|ref|XP_007176138.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Balaenoptera acutorostrata scammoni]
MAQQTASPDTLTVPEMDNPHCPNPWLNEDLVKSLRENLLQHEKSKTAKKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
AEEEAVGEEEEESQPEACAIGAHSPDT
>gi|533157523|ref|XP_005392721.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Chinchilla lanigera]
MAQQASPDTLTVPEVDNPHGPNPWLNEDLVKSLRENLLQHEKSKTTRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQR
RFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVT
PFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGQQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEESQPEVCVVDDCSPDT
>gi|505801936|ref|XP_004608510.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Sorex araneus]
MAQQTTSPDTLAVPEVDNPHAPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPTPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDPEEGRQGQTDKFQFELTLEEDGESDTEKDCGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEEECQPEASVVEDHSPDT
>gi|466035397|ref|XP_004275221.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Orcinus orca]
MAQQTASPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
AEEEAVGEEESQPEACAIGDHSPDT
>gi|617572944|ref|XP_007516961.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Erinaceus europaeus]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTTRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEAEGEEEECQPETCVVEEDHCPDT
>gi|602680953|ref|XP_007453280.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Lipotes vexillifer]
MAQQTASPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
AEEEAVGEEERQPEACAIGDHSPDT
>gi|532027736|ref|XP_005356835.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Microtus ochrogaster]
MAQQTTSPDTLTVPEVDNPHVPNPWLNEDLVKSLRENLLQHEKSKTARKSASPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVAEEEASQPETCAIDDGCPDT
>gi|488534356|ref|XP_004458891.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Dasypus novemcinctus]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQERELLKTFKIPVDTLITYLMTLEDHYHADVAYHN
YIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEESQPEACVIEDHSPDT
>gi|625183271|ref|XP_007646078.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Cricetulus griseus] >gi|625233414|ref|XP_007607854.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Cricetulus griseus]
MAQQTTSPDTLTVPEVDNPHVPNPWLNEDLVKSLRENLLQHEKSKTARKSASPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVAEEEGNQPETCVIDDCCPDT
>gi|560908209|ref|XP_006180422.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Camelus ferus]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQQEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLVLQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPEDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEEENQPEAHVIEDHSPDT
>gi|524922708|ref|XP_005065608.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Mesocricetus auratus]
MAQQTTSPDTLTVPEVDNPHVPNPWLNEDLVKSLRENLLQHEKSKTARKSASPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVAEEEGNQPETCVIEDCCPDT
>gi|148686495|gb|EDL18442.1| phosphodiesterase 4D, cAMP specific, isoform CRA_c [Mus musculus]
KTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQR
RESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKAT
ITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIP
SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTI
FQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHP
GVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASV
EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESD
TEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPETCVPDDCCPDT
>gi|164519074|ref|NP_001106803.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Rattus norvegicus] >gi|118500412|gb|ABK97408.1| cAMP-specific phosphodiesterase PDE4D splice variant 5 [Rattus norvegicus]
MAQQTTSPDTLTVPEVDNPHVPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVAEEESQPQTGVADDCCPDT
>gi|649148980|gb|AIC62005.1| PDE4C, partial [synthetic construct]
MASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFG
VQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSL
HAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQA
ENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPT
KPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVYPDAQDLLDTLEDNR
EWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQR
T
>gi|478497129|ref|XP_004422903.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Ceratotherium simum simum]
MAQQTTSPDTLTVPEVDNPHGPNPWLNEDLVKSLRENLLQNEKSKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQSMVHCADLSN
PTKPLQLYRQWTDRVMEEFFRQGDRERERGMEISPMCDKHSASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEEESQPEACAIEDPSPDT
>gi|426246449|ref|XP_004017006.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Ovis aries]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEATRGAREEA
REAGGGAQPEACVAGEPSPGT
>gi|568984457|ref|XP_006517707.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Mus musculus]
MAQQTTSPDTLTVPEVDNPHVPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVAEEESQPETCVPDDCCPDT
>gi|390459919|ref|XP_003732386.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Callithrix jacchus] >gi|403267507|ref|XP_003925870.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Saimiri boliviensis boliviensis]
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQR
RFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVT
PFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESQPEACVIDDRSPDT
>gi|548511762|ref|XP_005694734.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Capra hircus]
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQQEKPKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEATRGGGGGG
GGGGGGGPSRRPASPGSPPRARNGAQTPMPFVCVFCFFK
>gi|635028348|ref|XP_007971521.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Chlorocebus sabaeus]
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQR
RFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVT
PFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESQSEACVIDDRSPDT
>gi|507649543|ref|XP_004703648.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Echinops telfairi]
MAQQTPSPDTLTVPEVDNPHGPNPWLNEDLVKSLRENLLQHEKSKTSRKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRNSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDPEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEITLDEQ
VEEEAVGEETESQAEACVDEHSPDT
>gi|308387374|ref|NP_001184147.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D5 [Homo sapiens] >gi|332233627|ref|XP_003266005.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Nomascus leucogenys] >gi|397514340|ref|XP_003827447.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Pan paniscus] >gi|426384626|ref|XP_004058860.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 1 [Gorilla gorilla gorilla] >gi|544437299|ref|XP_005557013.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Macaca fascicularis] >gi|2735857|gb|AAC00069.1| cAMP-specific phosphodiesterase PDE4D5 [Homo sapiens] >gi|119575378|gb|EAW54983.1| phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila), isoform CRA_b [Homo sapiens]
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQR
RFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVT
PFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESQPEACVIDDRSPDT
>gi|297294334|ref|XP_002804419.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Macaca mulatta]
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQR
RFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVT
PFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESHPEACVIDDRSPDT
>gi|583989287|ref|XP_006789852.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Neolamprologus brichardi]
MAQQAGMGVTHQDTLAVPPMPKHSGLNEDLVKILRENLLQPERPRGHRRSPSSISPRLSPRNSPRLLRRMLLNNNIHKQR
RFTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVT
PFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIP
RFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYH
NNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEENSCTDSKTLCTQDSE
STEIPLDEQVGEDDDDDDEVVEEGETPCSQSFVVEEEVAEEEEEEEEEEKAKSPDT
>gi|527267748|ref|XP_005151988.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Melopsittacus undulatus]
MAQATSPDAFIVSEGDNSRCQNPCLNEDLVKTLRENLLQYENSRTSKKSSSTSPRLCPVISPRNSPRLLRRMLISNNIPK
QRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
VTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKASLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPAQKEKEKKKRPMSQISGVKKLMHSTSLTNSSIP
RFGVKTEHEESLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHSDVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLSKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLDLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVHPLWETWADLVHPDAQEILDTLE
DNREWYQSTIPQSPSPAADDQEESKQTQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
PVGEEVEEEENQTEPCVVEGHTPNT
>gi|498969924|ref|XP_004547274.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Maylandia zebra] >gi|542225975|ref|XP_005452166.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Oreochromis niloticus]
MAQQAGMGVTHQDTLAVPPMPKHSGLNEDLVKILRENLLQPERPRGHRRSPSSISPRLSPRNSPRLLRRMLLNNNIHKQR
RFTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVT
PFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIP
RFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYH
NNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDSKTLCTQD
SESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|301617608|ref|XP_002938226.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Xenopus (Silurana) tropicalis]
MEETSVATCTAEMAQQVAASSDTLAVPEVDNPHCHNNAWLNEDLVNTLRENLLQHDRCKVPRKPISPRLSPVISPRNSPR
LLRRMLLNSNIPKQRRFTVAHTCFDVDNGTTSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYELSPKSMSRN
SSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKLAGETLEELDWCLD
QLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKK
LMHSSSLTNSNIPRFGVKSENEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLM
TLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSS
VLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRI
QVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADL
VHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLC
TQDSESTEIPLDDQVDEEESQLEPNSIEQAHSPDT
>gi|664753921|ref|XP_008534437.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Equus przewalskii]
MIVTPFAQVLASLRTVRSNVAALAHLQGRGATKQAPVGKPPSGSQAPPSTEDPGQKLALETLDELDWCLDQLETLQTRHS
VGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPRVTPTEPPKPISQISGLRGLPHSASLSAATFP
RFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLVTYLLTLEGHYRADVAYH
NSLHAADVAQSTHVLLATPALQAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKL
LQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVASLGVLLLDTDRIQVLQNLVHCADLSNP
TKPLPLYRQWTDRIMAEFFQQGDRERESGLDVSPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDN
REWYQSKVPRSPMDPTSPEQGSPDRFQFELTLDEAEEEKEAEEEGALDGEASESPDTELLSPEASLDPGGLLLDNQRTAG
KPCKNHEGGVMAEPFGN
>gi|658867461|ref|XP_008416603.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Poecilia reticulata]
MAQQGGTGVAHQDTLAVPPMPKHSGLNEDLVKILRENLLQPERPRGHRRSPSSISPRLSPRNSPRLLRRMLLNNNIHKQR
RFTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVT
PFAQVLASLRTVRNNFGTLTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIP
RFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYH
NNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDSKTLCTQD
SESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAANEEVAEDEEEEKSPDT
>gi|657815914|ref|XP_008335087.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Cynoglossus semilaevis]
MAQQAGMGVTHQDTLAVPPMPKHSGLNEDLVKILRENLLQPERPRGHRRSPSSISPRLSPRNSPRLLRRMLLNNNIHKQR
RFTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVT
PFAQVLASLRTVRNNFGALTNLQQDRVFNKRSPMCNPAPITKTAFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVELPSPHMQKEKEKKNKPMSQISGVKKLQHSSSLSNSNIP
RFGVKTETENELAKELEHVNKWGLNVFKISEFSGNQPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYH
NNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYCQWTDRIMEEFYSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEDEEEEDNSCTDSKTLCTQDSES
TEIPLDEQVVEEEEEVAKNQEEVPCLQPCVLEDVAEVEDNKKSSDT
>gi|617386794|ref|XP_007548207.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Poecilia formosa]
MAQQGGTGVAHQDTLAVPPMPKHSGLNEDLVKILRENLLQPERPRGHRRSPSSISPRLSPRNSPRLLRRMLLNNNIHKQR
RFTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVT
PFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIP
RFGVKTETEDELAKELEHVNKWGLNLFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYH
NNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEEENSCTDSKTLCTQ
DSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAADEEVAEDEKEGKSPDT
>gi|542225977|ref|XP_005452167.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Oreochromis niloticus]
MAQQAGMGVTHQDTLAVPPMPKHSGLNEDLVKILRENLLQPERPRGHRRSPSSISPRLSPRNSPRLLRRMLLNNNIHKQR
RFTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVT
PFAQVLASLRTVRNNFGALTNLHPLKRALTDPLPSCLAPAEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFK
RMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKT
ETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAA
DVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENC
DIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPL
QLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY
QSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDSKTLCTQDSESTEI
PLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|119605084|gb|EAW84678.1| phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila), isoform CRA_d [Homo sapiens]
MPRSSQFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRF
GVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNS
LHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQ
AENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNP
TKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDN
REWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQ
RT
>gi|114600123|ref|XP_001138610.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 8 [Pan troglodytes]
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQR
RFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVT
PFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRIYKKELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESQPEACVIDDRSPDT
>gi|594655495|ref|XP_007176136.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Balaenoptera acutorostrata scammoni]
MAQQTASPDTLTVPEMDNPHCPNPWLNEDLVKSLRENLLQHEKSKTAKKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTAEVIPEELKSRLEVISEEGGYPSLLTAEEAYQKL
ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEK
KKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKT
FKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLIN
TNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS
SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFID
YIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQV
EEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVGEEEEESQPEACAIGAHSPDT
>gi|2706891|gb|AAB96877.1| PDE4C-delta54, partial [Homo sapiens] >gi|3688085|gb|AAC83051.1| PDE4C-delta54 [Homo sapiens]
PLRIRPLLPTAYHLLPTGPGQSADRSEQRGGPCPPAMPRSSQFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVE
LPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIF
QERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPG
VSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTM
VETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVE
KSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEE
EGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|513229254|ref|XP_004937311.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Gallus gallus]
MAQQTSPDTLAVPEVDNSPCQNPWLNEDLVKTLRENLLQYEKSGTSKKSSSASPRLSPVISPRNSPRLLRRMLLNSNIPK
QRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
VTPFAQVLASLRTVRNNFAALTNLQDRAPSNRRSPRAGEPPVKRLRTQHAFPCLFAEEAYQKLASETLEELDWCLDQLET
LQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHS
SSLTNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTVFQERDLLKTFKIPVDTLITYLMTLED
HYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLEN
HHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQ
NMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPD
AQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDS
ESTEIPLDEQVGEEVEEEENQTESCVVDHSPDT
>gi|597742195|ref|XP_007233210.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Astyanax mexicanus]
MSETSEEESSLSSGTQPIRLKPRSCANSPCGSPNSRQSPRNSPRNSPLLFRKLLMNRSIVLQRRFTLAHTPSFDVENGLS
AGRALDPQVSPSSGLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELHGEDMIVTPFAQVLASLRTVRSNFA
ALTHLQDRGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSE
TSRSGNQVSEFIASTFLEKQHDVEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVEDI
NRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSP
ALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQS
LRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVE
YFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSPSPTPE
EQDSQGGGSGSLGAGGAGGEKFQFELTLEEEGESDAESPPAAESSRNPTDSLNRAPSPHPSQTLGLAAMSVRSPRHRTLS
PDTADRDSSRERD
>gi|541985569|ref|XP_005444382.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Falco cherrug]
MLPTAHCSPGASPAASPRNSPRNSPILFRKLLMNQSIRLQRRFTVAHPLCFDLENGPPGRGVLDPQASPGAGLVLQGTFP
HGQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTIRSNLTHLQDRASIKRASSSSLPSGSKA
SLTEDAHQKLSRETLEELDWCLDQLETLQTRHSVSEMASNKLNRELSHLSETSRSGNQVSEYISSTFLDKQHEVEIPSAL
AKDKEKERRKRPMSQISGVRKLTHGSSLATTGIPRFGVRTDQEGLLAKELEDTNKWGLNVFKVAEYSGNRPLTVIMYSIF
QERDLMKTFRIPVSTFITYMLTLEDHYHADVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPG
VSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMAIDMVLATDMSKHMNLLADLKTM
VETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEISPMCDKHTASVE
KSQVGFIDFIAHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPPPEGPGVSPASTDKFQFELMLEEEEEGESD
TELEGAESPLDEDNSGSKTPATDDSESADTKCLSPSPGDQDSPVTRPRDVDNRRALEGTLPKDASGGGCSVPGPEGSQGL
CLDREGNVTFLPLGT
>gi|532067620|ref|XP_005319656.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Ictidomys tridecemlineatus]
MAQQTTSPDTLTVPEVDNPHGPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQ
RRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIV
TPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLKELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIQDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKXXXXXVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEEAVGEEESQPEAPVIDDCSPDT
>gi|149059313|gb|EDM10320.1| rCG44727, isoform CRA_d [Rattus norvegicus]
MLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIA
SDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLET
LQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHS
SSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLED
HYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLEN
HHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQ
NMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPD
AQDILDTLEDNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDS
ESTEIPLDEQVEEEAVAEEESQPQTGVADDCCPDT
>gi|454526968|ref|NP_001263694.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Rattus norvegicus] >gi|564388508|ref|XP_006252930.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Rattus norvegicus] >gi|149036064|gb|EDL90730.1| phosphodiesterase 4C, cAMP-specific, isoform CRA_b [Rattus norvegicus]
MRRSGTTLSFLLTERVREPVDSGVAPVSHLGGGVILRRFSGTLLLPPLSSRLGSSGEAESAAPVVFTIGSRGTERSHGSA
QSSFDLENGLPSGRGPLDAQSGSSLGRALQPPVHHGQRRESFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQV
LASLRTVRSNVAALAHGAGSATRQALLGTPPQSSQQAAPAEESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFK
RMLNRELTHLSETSRSGNQVSEYISQTFLDQQAEVELPAPPTEDHPWPMAQITGLRKSCHTSLPTAAIPRFGVQTDQEEQ
LAKELEDTNKWGFDVFKVAELSGNRPLTAVIFSVLQERDLLKTFQIPADTLLRYLLTLEGHYHSNVAYHNSIHAADVVQS
AHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQN
LSTKQKLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQ
WTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNREWYQSRVP
CSPPHAIGPDRFKFELTLEETEEEEEEDERH
>gi|554559060|ref|XP_005873928.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X5 [Myotis brandtii]
MAGHRTPQCQACLGLTGLVFRDACSMRRSGTALSFLLSEQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPP
GETEPSSCVVFTIGAQGTEQSHGPASSSFDLENALSRGRSAQDPQVGPGPGQVTQHSQRRESFLYRSESDYELLPKAMSR
NSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWC
LDQLETLQTRHSVGEMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGL
PHSASLSTATIPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLT
LEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASV
LENHHLAVGFKLLQAENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQ
QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSPGDPTSPEQ
GGLDRFQFELTLEEAEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAEPSGS
>gi|148696916|gb|EDL28863.1| phosphodiesterase 4C, cAMP specific, isoform CRA_a [Mus musculus]
RTQLGVGQDRLSSAPGRSQSTLTAQVPTGAAGKACTMRRSGTALSFLWTERVREPVDSGVAPVSPLGGGVILRRFSGTLL
LPPLSSRLGSSGEAESAAHVVFTIGTQGTQRNLGSAQSSFDLENGLPGGKGLLDAQSGPSLGRALQPPVHHVQRRESFLY
RSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQVLASLRTVRNNVAALAHGPGSATRQVLLGTPPHSSQQAAPTEDSG
LQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELSYLSETSRSGNQVSEYISQTFLDQQAEVELPQPPTED
DPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTF
QIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINT
NSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSL
GVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDY
IAQPLWETWADLVHPDAQELLDTLEDNREWYQSRIPCSPPHTMGSDRFKFELTLEEAEEEEEEEDEGQCTALNRESSELP
ST
>gi|149036065|gb|EDL90731.1| phosphodiesterase 4C, cAMP-specific, isoform CRA_c [Rattus norvegicus]
METRLVGHTGVPPPPKHLWGQPQRPIRIQRRFHSDPERPDRPAPVKSRRSWPSSFHRRFDLENGLPSGRGPLDAQSGSSL
GRALQPPVHHGQRRESFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGSATRQA
LLGTPPQSSQQAAPAEESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYIS
QTFLDQQAEVELPAPPTEDHPWPMAQITGLRKSCHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGFDVFKVAELSGNR
PLTAVIFSVLQERDLLKTFQIPADTLLRYLLTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFA
CAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVIDMVLATDMSKH
MSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISP
MCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNREWYQSRVPCSPPHAIGPDRFKFELTLEETEEEE
EEDERH
>gi|529449140|ref|XP_005244256.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Falco peregrinus]
MLPTAHCSPGASPAASPRNSPRNSPILFRKLLMNQSIRLQRRFTVAHPLCFDLENGPPGRGVLDPQASPGAGLVLQGTFP
HGQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTIRSNLTHLQDRASIKRASSSSLPSGSKA
SLTEDAHQKLSRETLEELDWCLDQLETLQTRHSVSEMASNKVRLSHLSETSRSGNQVSEYISSTFLDKQHEVEIPSALAK
DKEKERRKRPMSQISGVRKLTHGSSLATTGIPRFGVRTDQEGLLAKELEDTNKWGLNVFKVAEYSGNRPLTVIMYSIFQE
RDLMKTFRIPVSTFITYMLTLEDHYHADVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMAIDMVLATDMSKHMNLLADLKTMVE
TKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEISPMCDKHTASVEKS
QVGFIDFIAHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPPPEGPGVSPASTDKFQFELMLEEEEEGESDTE
LEGAESPLDEDNSGSKTPATDDSESADTKCLSPSPGDQDSPVTRPRDVDNRRALEGTLPKDASGGGCSVPGPEGSQGLCL
DTEGNVTFLPLGT
>gi|597742187|ref|XP_007233206.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Astyanax mexicanus]
MSETSEEESSLSSGTQPIRLKPRSCANSPCGSPNSRQSPRNSPRNSPLLFRKLLMNRSIVLQRRFTLAHTPSFDVENGLS
AGRALDPQVSPSSGLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFA
QVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNK
FKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDVEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVS
TEHESLLAKEVEDINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHA
ADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEEN
CDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
YQSMIPHSPSPTPEEQDSQGGGSGSLGAGGAGGEKFQFELTLEEEGESDAESPPAAESSRNPTDSLNRAPSPHPSQTLGL
AAMSVRSPRHRTLSPDTADRDSSRERD
>gi|84029388|sp|Q3UEI1.1|PDE4C_MOUSE RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Mus musculus] >gi|74146321|dbj|BAE28930.1| unnamed protein product [Mus musculus]
MRRSGTALSFLWTERVREPVDSGVAPVSPLGGGVILRRFSGTLLLPPLSSRLGSSGEAESAAHVVFTIGTQGTQRNLGSA
QSSFDLENGLPGGKGLLDAQSGPSLGRALQPPVHHVQRRESFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQV
LASLRTVRNNVAALAHGPGSATRQVLLGTPPHSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFK
RMLNRELSYLSETSRSGNQVSEYISQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQ
LAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQS
AHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRN
LSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQ
WTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQSRIP
CSPPHTMGSDRFKFELTLEEAEEEEEEEDEGQCTALNRESSELPST
>gi|148696918|gb|EDL28865.1| phosphodiesterase 4C, cAMP specific, isoform CRA_c [Mus musculus]
LMETQLVGRAGVPRSPKHLWGQLQRPIRIQRRFHSDPERPDRPAPVKSRLSWPSSFHRRFDLENGLPGGKGLLDAQSGPS
LGRALQPPVHHVQRRESFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQVLASLRTVRNNVAALAHGPGSATRQ
VLLGTPPHSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELSYLSETSRSGNQVSEYI
SQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGN
RPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIF
ACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSK
HMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDIS
PMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQSRIPCSPPHTMGSDRFKFELTLEEAEEE
EEEEDEGQCTALNRESSELPST
>gi|507964132|ref|XP_004688234.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Condylura cristata]
MSRNSSVASDLHGEDMIVTPFAQVLASLRTVRGNLAALAHLPGRWSPEDTGQKLALETLDELDWCLDQLETLQTRRSVGE
MASTKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELSRVTPMAPPRPMSQISGLHGLPHSTSLSEAPVPRFG
VQTNQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLVTYLLTLESHYHADVAYHNSI
HAADVAQSAHVLLATPALEAVFTDLEVLATIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQA
ENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLMLDNYSDRIQVLQNLVHCADLSNPT
KPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNR
EWYQSKIPRSPVDPTGPERSGPDRFQFELTLEEAEEEEEEEEGTLDCGVSESPDTELLSPEVRLDPGTPQPDSQRTVGQA
CVDHREM
>gi|641771534|ref|XP_008169804.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Chrysemys picta bellii]
MNAIKRRFSGTPLLPPLACRHVALSEASRPPESEGPRVVFTIEESRPSSGQEPGFLRFDIENGLSSGRSPLDPQASPGSG
LVLQGNVPHSQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVASKRT
SSSNPPSVCKASLSEDACQKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISS
TFLDKQHEVEIPSPTPKEKEAEKTTRPMAQISGLKKLTHSSSFISSSIPRFGVKTDQEGLLAKELKDTNKWGLDMFKITE
YSGNRPLTVVMYSIFQERDLMKTFSIPADTFITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEVM
AAIFASAIHDVDHPGVSNQFLINTNSELALMYNDVSVLENHHLAVGFKLLQEENCDIFQHLSKKQRQSLRKMAIDMVLAT
DMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKG
MEISPMCDKLSASVEKSQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPPEEQDPEKGGGGEKF
QFQLTLEEEGESDTEPEEAESPLEEDNSGSDSKMLATDDSESPELERLSPGSAGRDSPPPTPSGPLRNTLVKQKEALHFD
NRRALERTLSQPDGGTSELGRRGSLEAKELALDTEGNLTFLPLGT
>gi|612011954|ref|XP_007489291.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Monodelphis domestica]
MESPGGGGSGEVEAAAEVAEAIRLCRALSREGAGSAKPPKHLWRQPRTRIRIQQRFHSDTDKYLSTRSSRPGLRKSRRSW
PSSFHKRFDLENGLSSGRSPLDPQTSPGSGLVIQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSTASDLHGEDMIVTP
FAQVLASLRTVRSNFAVLTRLQDRVAKRVSGSNPTSGCRAPPLPEDACQKLAMETLEELDWCLDQLETLQTRHSVSEMAS
NKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDKQHEVELPSMPVKEREKEKEERPMSQISGVRKLTHGSSFSAAAIPR
FGVKTDHETLLAKELKDTNKWGLDVFKVAELSGNRPLTAIMYSIFQERDLLKTFRIPVDTLVTYLLTLEDHYHADVAYHN
SIHAADVAQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLL
QEDNCDIFQNLRPKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLELYRQWTDRIMVEFFQQGDREREKGIEISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQEILDTLED
NREWYQSMIPRSPDGGHEAGPAKGGGAADKFQFELTLEEEEGESDSEAEEPGSRAEEGEEENSGSDSKTLATDDSESAEV
EPLSPEEEASPVEEHRPQASVALDNERTLSQAEAKSLQEGDGAVDQEGNLTFYPLGT
>gi|612011952|ref|XP_007489290.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Monodelphis domestica]
MRRSRTAASFLPNERAREAAELGAAGVGPPGSSAVRRRFSGTPQLPPLTWRHGPVGEAARALEPEASARVVFSIEERVPE
RGGHPPTGGSFDLENGLSSGRSPLDPQTSPGSGLVIQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSTASDLHGEDMI
VTPFAQVLASLRTVRSNFAVLTRLQDRVAKRVSGSNPTSGCRAPPLPEDACQKLAMETLEELDWCLDQLETLQTRHSVSE
MASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDKQHEVELPSMPVKEREKEKEERPMSQISGVRKLTHGSSFSAAA
IPRFGVKTDHETLLAKELKDTNKWGLDVFKVAELSGNRPLTAIMYSIFQERDLLKTFRIPVDTLVTYLLTLEDHYHADVA
YHNSIHAADVAQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGF
KLLQEDNCDIFQNLRPKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLELYRQWTDRIMVEFFQQGDREREKGIEISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQEILDT
LEDNREWYQSMIPRSPDGGHEAGPAKGGGAADKFQFELTLEEEEGESDSEAEEPGSRAEEGEEENSGSDSKTLATDDSES
AEVEPLSPEEEASPVEEHRPQASVALDNERTLSQAEAKSLQEGDGAVDQEGNLTFYPLGT
>gi|513229263|ref|XP_004937314.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Gallus gallus]
MSIVMKPRSRSTSSLRTVEAMCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTVFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVGEEVEEEENQTESCVVDHSPDT
>gi|612011950|ref|XP_007489289.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Monodelphis domestica]
MMAGSHGSLLSAGPAQRPRVPAMRRSRTAASFLPNERAREAAELGAAGVGPPGSSAVRRRFSGTPQLPPLTWRHGPVGEA
ARALEPEASARVVFSIEERVPERGGHPPTGGSFDLENGLSSGRSPLDPQTSPGSGLVIQGNFPHSQRRESFLYRSDSDYD
LSPKAMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNFAVLTRLQDRVAKRVSGSNPTSGCRAPPLPEDACQKLAMET
LEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDKQHEVELPSMPVKEREKEKEE
RPMSQISGVRKLTHGSSFSAAAIPRFGVKTDHETLLAKELKDTNKWGLDVFKVAELSGNRPLTAIMYSIFQERDLLKTFR
IPVDTLVTYLLTLEDHYHADVAYHNSIHAADVAQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTN
SELALMYNDASVLENHHLAVGFKLLQEDNCDIFQNLRPKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLG
VLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFQQGDREREKGIEISPMCDKHTASVEKSQVGFIDYI
AHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPDGGHEAGPAKGGGAADKFQFELTLEEEEGESDSEAEEPGSRA
EEGEEENSGSDSKTLATDDSESAEVEPLSPEEEASPVEEHRPQASVALDNERTLSQAEAKSLQEGDGAVDQEGNLTFYPL
GT
>gi|525026529|ref|XP_005060710.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Ficedula albicollis]
MSIVMKPRSRSTSSLRTADAMCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITEEAYQKLASETMEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCT
QDSESTEIPLDEQVGEEVEEEENQTAEPCMVEEHSPDT
>gi|507934230|ref|XP_004678348.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Condylura cristata]
MAFVWDPQRATVPGPSPRAKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRASSKRSPMCNQPSINKTTITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGHTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEACVIEDRSPDT
>gi|585679889|ref|XP_006891579.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Elephantulus edwardii]
MSIIMKPRSRSTSSLKTTDTVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEDAVGEAEESQPEVCIIEDHSPDT
>gi|586491552|ref|XP_006876231.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Chrysochloris asiatica]
MSIIMKPRSRSTSSLRTTETVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEESQPEACVIEDHSPDT
>gi|507934232|ref|XP_004678349.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Condylura cristata]
MSIIMKPRSRSTSSLRTSEALCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRASSKRSPMCNQPSINKTTITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGHTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEESQPEACVIEDRSPDT
>gi|562877028|ref|XP_006166282.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Tupaia chinensis]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEETVGEEEESQPEACVVEDHSPDT
>gi|505801945|ref|XP_004608513.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Sorex araneus]
MAFVGDPLGAAMPGPSPRAKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPTPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTDKFQFELTLEEDGESDTEKDCGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEECQPEASVVEDHSPDT
>gi|504142684|ref|XP_004583778.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Ochotona princeps]
MSIVMKPRSRSTSSLRTTEAVCFDVDNGTSTGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQAEEEAVAEEESQPEACVIDDCSPDT
>gi|542205054|ref|XP_005476147.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Oreochromis niloticus]
MNDLCSESSEEEQSEVDETPREQKLSRLPVIQLMSRTVGGSTGGSPKVSPKDSPRGSPRNSPLLFRKLLMNRSINLQRRR
FTLAHTPSFDVENGLSVGRSPLDPQASPNSGLARPTNFPHSQRRESFLYRSDSDFDLSPKGPSRNSSTASDLHTEDMIVT
PFAQVLASLRTVRSNFAVITGQQDRTASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCLEQLETLKTRHSVSEM
ASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKQHDMDIMSPPTKEKDKKKRPMSQISGVKKATHSPSLAPSTIPR
FGVNASQEGLLAKELEDINRWGIDIFKVSEYSGNRPLTVTMYTIFQERDLLKSFKIPVDTFITFMMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDLSVLENHHLAVGFKLL
QEDNCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLELYRQWTDRIMVEFFTQGDREREKGMEISPMCDKHNASVEKNQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSMIPHSPSPHPEGQEEEEEEEDTFAGEASAHCRGSGSASADKFQFKLTLEEEGESDTESPPEEEEGQSSSRRHE
IYRSDSASPASRRLPKMLTSDSGRTFSLDSEKDMAEERETDEGVSGVPRFRIGT
>gi|528922135|ref|XP_003583734.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Bos taurus] >gi|528998074|ref|XP_003587562.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX6 [Bos taurus]
MRQEVPAISSSCASATCHLAGSPEQAQRKCLPLATSAYCSSRGPPAPGLCTHSDLPLSPATPAPPSHMAFVWDPRGASVP
ALSTRVKSRSRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASD
IHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQ
TRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSS
LTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHY
HADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHH
LAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNM
VHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQ
DILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSES
TEIPLDEQVEEEAVADEESQPEACVIGDPSPDT
>gi|507615288|ref|XP_004623131.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Octodon degus]
MSIIMKPRSRSTSSLRTSEATCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGPQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGGGESQPEVCVTDECSPDT
>gi|507615282|ref|XP_004623128.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Octodon degus]
MIAVQTRELESIYENHYTHLGNEENINERRPASMMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFV
HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSI
NKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHE
VEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVI
MHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHD
VDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLA
DLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKH
NASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGPQGQTEKFQFELTLEED
GESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGGGESQPEVCVTDECSPDT
>gi|641695227|ref|XP_008160063.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Eptesicus fuscus]
MSIIMKPRSRSTSSLKTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDHSPDT
>gi|602652298|ref|XP_007432522.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Python bivittatus]
MTMNPNLRLQRRFTVAHPLCFDVENGFSPGRSPLDSQANLGLGLVLQGTTPHSQRRESFLYRSDSDYDLSPKAMSRNSSV
SSDMHGEDLIVTPFAQVLASLRTVRSNFAVLTHLREHVCNKASGSINPPSASKVNLSEDAYQKLAIETLEELDWCLDQLE
TLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISNTFLDKQHEVEIPTSVPKEKDKEKKKRPMSQISGVKKL
MHGSSFNCAAIPRFGVKTDQEGPLAKELEDVNKWGLDVFKIAEYSGHRPLTVIMYSIFQERDLLKSFHIPADTFITFMMT
LEDHYHADVAYHNNIHAADVAQSTHVLLSMPALEAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDASV
LENHHLAVGFKLLQEENCDIFQNLSKKQRQMLRKMAIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQ
VLQNIVHCADLSNPTKPLELYRQWTDRIMIEFFHQGDREREKGMEISPMCDKHNASIEKSQVGFIDYIAHPLWETWADLV
HPDAQEILDTLEDNREWYQSMIPHSPSPPPDASGLEKNGGVPEKFKFQLTLEEEDGEESDIEQEVESPLEEDNSESKTLG
TTDDSESANEPLPSPTDKLGSPHRNALIKQKGALDFDNQRTLSQTDSGSIADPVELARRDSLTDAQSCLDMEGNITFLPL
GT
>gi|584085530|ref|XP_006762503.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Myotis davidii]
MSIIMKPRSRSTSSLKTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRPGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEVPLDEQVEEEAVGDEEESQPEACVIDDHSPDT
>gi|558177204|ref|XP_006100423.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X4 [Myotis lucifugus]
MAGHRTPQCQACLGLTEPVFRDACSMRRSGTALSFLLSEQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPP
GETEPSSCVVFTIGARGTEQSHGPASSSFDLENALSRGRSAQDPQVGLGPGQVTQHSQRRESFLYRSESDYELLPKAMSR
NSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWC
LDQLETLQTRHSVGDMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGL
PHSASLPTATTPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLT
LEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASV
LENHHLAVGFKLLQAENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQ
QGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSPVDPTSPEQ
GGLDRFQFELTLEEAEEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAEPSGS
>gi|525026531|ref|XP_005060711.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Ficedula albicollis]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITEEAYQKLASETMEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSEST
EIPLDEQVGEEVEEEENQTAEPCMVEEHSPDT
>gi|513229266|ref|XP_004937315.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Gallus gallus]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTVFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVGEEVEEEENQTESCVVDHSPDT
>gi|471392354|ref|XP_004380554.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 5 [Trichechus manatus latirostris]
MSIIMKPRSRSTSSLRTTEAICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEERQPEACVIEDHSPDDT
>gi|345794110|ref|XP_003433853.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX4 [Canis lupus familiaris]
MSIIMKPRSRSTSSLRTTEAACFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEETVGEEENSQPEACVIEDHSPDT
>gi|586491554|ref|XP_006876232.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Chrysochloris asiatica]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEESQPEACVIEDHSPDT
>gi|585679903|ref|XP_006891583.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Elephantulus edwardii]
MAFVWEPLGAMVPGPSPRAKTRLRFAKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEDAVGEAEESQPEVCIIEDHSPDT
>gi|472378762|ref|XP_004408799.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 6 [Odobenus rosmarus divergens]
MSIIMKPRSRSTSSLRTTEAACFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEETVGEEEDSQPAACVIEDHSPDT
>gi|594082614|ref|XP_006064902.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Bubalus bubalis]
MAFVWDPRGASVPALSTRVKSRSRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQGEEEAVADDEESQPEACVIGDPSPDT
>gi|585679893|ref|XP_006891580.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Elephantulus edwardii]
MNMMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIAS
DIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETL
QTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSS
SLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDH
YHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENH
HLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQN
MVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDA
QDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSE
STEIPLDEQVEEDAVGEAEESQPEVCIIEDHSPDT
>gi|545199152|ref|XP_005604254.1| PREDICTED: phosphodiesterase 4D, cAMP-specific isoform X5 [Equus caballus] >gi|664711481|ref|XP_008512716.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Equus przewalskii]
MAFVWDLQGVPVPRPSLRAKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACAAEDRSPDT
>gi|530564981|ref|XP_005279061.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Chrysemys picta bellii]
MPSPPWAAAPQSPLDLGVQRKALWGASHGRSAGGATGRPMGVSGQAPALEEKTRSPCRCAGAWPCWRGSSWRAQDRMSLP
TSCGSVALADCALMVCNGHLAGSPRAVNRPIDIAQKHRRFDIENGLSSGRSPLDPQASPGSGLVLQGNVPHSQRRESFLY
RSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVASKRTSSSNPPSVCKASLSEDAC
QKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDKQHEVEIPSPTPKE
KEAEKTTRPMAQISGLKKLTHSSSFISSSIPRFGVKTDQEGLLAKELKDTNKWGLDMFKITEYSGNRPLTVVMYSIFQER
DLMKTFSIPADTFITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEVMAAIFASAIHDVDHPGVSN
QFLINTNSELALMYNDVSVLENHHLAVGFKLLQEENCDIFQHLSKKQRQSLRKMAIDMVLATDMSKHMNLLADLKTMVET
KKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEISPMCDKLSASVEKSQ
VGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPPEEQDPEKGGGGEKFQFQLTLEEEGESDTEPEE
AESPLEEDNSGSDSKMLATDDSESPELERLSPGSAGRDSPPPTPSGPLRNTLVKQKEALHFDNRRALERTLSQPDGGTSE
LGRRGSLEAKELALDTEGNLTFLPLGT
>gi|507934234|ref|XP_004678350.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Condylura cristata]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRASSKRSPMCNQPSINKTTITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGHTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEESQPEACVIEDRSPDT
>gi|504142682|ref|XP_004583777.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Ochotona princeps]
MAFLWDPLGITVPGPSPRAKSRLRLSKSYSFDVDNGTSTGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQAEEEAVAEEESQPEACVIDDCSPDT
>gi|466035430|ref|XP_004275227.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 9 [Orcinus orca]
MAFVWDLRGVTVPGPSTRVKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQAEEEAVGEEESQPEACAIGDHSPDT
>gi|585151186|ref|XP_006728031.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Leptonychotes weddellii]
MSIIMKPRSRSTSSLRTTEAACFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEETVGEEEDSQPEACVIEDHSPDT
>gi|390459924|ref|XP_003732388.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Callithrix jacchus]
MSIIMKPRSRSTSSLRTAEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|555953888|ref|XP_005889113.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Bos mutus]
MAFVWDPRGASVPALSTRVKSRSRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVADEESQPEACVIGDPSPDT
>gi|358417734|ref|XP_003583730.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Bos taurus] >gi|359077379|ref|XP_003587558.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX2 [Bos taurus] >gi|555953890|ref|XP_005889114.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Bos mutus]
MSIIMKPRSRSTSSLRTSEGVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVADEESQPEACVIGDPSPDT
>gi|617572957|ref|XP_007516964.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Erinaceus europaeus]
MSIIMKPRSRSTSSLRTTEAVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEAEGEEEECQPETCVVEEDHCPDT
>gi|594655511|ref|XP_007176144.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Balaenoptera acutorostrata scammoni]
MAFVWDLRGVTVPGPSTRVKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQAEEEAVGEEEEESQPEACAIGAHSPDT
>gi|586491560|ref|XP_006876235.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X9 [Chrysochloris asiatica]
MAFVWDHLEATVPGPSPRAKTRLRFAKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIEDHSPDT
>gi|585151184|ref|XP_006728030.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Leptonychotes weddellii]
MAFLWDPQGVTVPGPSPRAKTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEETVGEEEDSQPEACVIEDHSPDT
>gi|545199148|ref|XP_005604252.1| PREDICTED: phosphodiesterase 4D, cAMP-specific isoform X3 [Equus caballus] >gi|664711483|ref|XP_008512717.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Equus przewalskii]
MSIIVKPRSRSTSSLRTTEAACFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEESQPEACAAEDRSPDT
>gi|533157531|ref|XP_005392725.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Chinchilla lanigera]
MSIIMKPRSRSTSSLRTTEATCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGQQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEESQPEVCVVDDCSPDT
>gi|507615286|ref|XP_004623130.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Octodon degus]
MAFVWDPPGVTAAGSSPRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGPQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGGGESQPEVCVTDECSPDT
>gi|505801948|ref|XP_004608514.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Sorex araneus]
MSIIMKPRSRSTSSLRTTEAVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPTPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTDKFQFELTLEEDGESDTEKDCGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEECQPEASVVEDHSPDT
>gi|602680961|ref|XP_007453284.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Lipotes vexillifer]
MAFVWDLRGVTVPGPSTRVKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQAEEEAVGEEERQPEACAIGDHSPDT
>gi|594082616|ref|XP_006064903.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Bubalus bubalis]
MSIIMKPRSRSTSSLRTSEGVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQGEEEAVADDEESQPEACVIGDPSPDT
>gi|556740074|ref|XP_005965585.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Pantholops hodgsonii]
MAFVWDPRGASVPALSTRVKSRSRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDCQTLCTQDSEATETPLDEQVEEEAVAGGEGAQPEACVAGEPSPGT
>gi|542162322|ref|XP_005489828.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Zonotrichia albicollis]
MAFLWDPFGANMPRPSPRNKMRFRFLKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITEEAYQKLASETME
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSF
SDSKTLCTQDSESTEIPLDEQVGEEVEEEENQTAESCVVEEHSPDT
>gi|533157525|ref|XP_005392722.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Chinchilla lanigera]
MIAAQTRQLESICENHYTNLGNKENINERRSANMMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFV
HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSI
NKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHE
VEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVI
MHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHD
VDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLA
DLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKH
NASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGQQGQTEKFQFELTLEED
GESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEVCVVDDCSPDT
>gi|513024651|ref|XP_004873536.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Heterocephalus glaber]
MRRSRTSLSFLRIERVREPLDSGPAPASPHGGGGIRRRFSGSPLLPLLCSHPGPPGEMGPSARVVFTIGARGTESSPGPA
AGRPGHGSGTNLLHGPTSSCPSSPTPRPPCCRGGKCSAPGKTPGTHPAWWAGAAWAHGDELLPLPFPEGLSPRRPVDPWP
SPAAPTVSRAPGTGRPARPPASLRPEPCGPTRVSSHRAPARDSSGSPCMATPGAAEGAEASSCLGRTRGRQGCPRPPKHL
WRQPRRPIRIQQRCHSDPDNPVGCRDPSRSARPGLRTTRRSWPTSFRQRFDLEHGPACGRGAQAPGSHGQRRESFLYRSD
SDYELSPKAMSRNSSAASDLHGEDLIVTPFAQVLASLRTVRSNVAALAHGHAHGATRPEPVESPPGRSPQVPDAEDAGRP
LALETLAELDWCLDQLEALHTRHSVGDMASTKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQCTDVEPPPRPLSEIP
GRGLSAAAVPRFGVQTDQEGKLAKELEDTNKWGLDVFRVAELSGNRPLTAILFSIFQERDLLKKFQIPADALATYLLTLE
GHYHADVAYHNSLHAADVAQSAHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGLSNQFLINTNSELALMYNDISVLE
NHHLAVGFKLLQAENCDIFRNLSAKQWLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKQVTSLGVLLLDTYADRIQVL
QNLVHCADLSNPTKPLPLYRQWTDRIMAEFFRQGDRERESGLDISPMCDKHTASVETSQVGFIDYIAHPLWETWADLVHP
DAQDLLDTLEDNRAWYQSRVPRSPVDTVSSERGAPDRFQFELTLAEAEEEAEEDGGQEESTASLCT
>gi|670997469|ref|XP_008689615.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Ursus maritimus]
MAFLWDPQGVTVPGPSPRAKARLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEETVGEEEESQPEACVVEDHSPDT
>gi|635028352|ref|XP_007971531.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Chlorocebus sabaeus]
MSIIMKPRSRSTSSLRTAEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEESQSEACVIDDRSPDT
>gi|308387380|ref|NP_001184149.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D9 [Homo sapiens] >gi|544437307|ref|XP_005557017.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Macaca fascicularis] >gi|32350926|gb|AAP75761.1| cAMP-specific phosphodiesterase variant PDE4D9 [Homo sapiens] >gi|37255983|gb|AAQ90404.1| cAMP-specific phosphodiesterase PDE4D9 [Homo sapiens] >gi|119575385|gb|EAW54990.1| phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila), isoform CRA_i [Homo sapiens]
MSIIMKPRSRSTSSLRTAEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|584085532|ref|XP_006762504.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Myotis davidii]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRPGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EVPLDEQVEEEAVGDEEESQPEACVIDDHSPDT
>gi|560908215|ref|XP_006180425.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Camelus ferus]
MSIIMKPRSRSTSSLRTSEGVCFDVDNGTSSGRSPLDPMTSPGSGLVLQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPEDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEENQPEAHVIEDHSPDT
>gi|511840331|ref|XP_004744670.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Mustela putorius furo] >gi|511942076|ref|XP_004789812.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Mustela putorius furo]
MSIIMKPRSRSTSSLRTTEAACFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEETVGEEEDSQPEPCGIEDHSPDT
>gi|488534360|ref|XP_004458893.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 6 [Dasypus novemcinctus]
MSIIMKPRSRSTSSLRTSETVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQERELLKTFKIPVDTLITYLMT
LEDHYHADVAYHNYIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEESQPEACVIEDHSPDT
>gi|472378764|ref|XP_004408800.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 7 [Odobenus rosmarus divergens]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEETVGEEEDSQPAACVIEDHSPDT
>gi|585151188|ref|XP_006728032.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Leptonychotes weddellii]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEETVGEEEDSQPEACVIEDHSPDT
>gi|345794108|ref|XP_003433852.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX3 [Canis lupus familiaris]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEETVGEEENSQPEACVIEDHSPDT
>gi|528922141|ref|XP_005196191.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Bos taurus] >gi|528998081|ref|XP_005221563.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X11 [Bos taurus]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVADEESQPEACVIGDPSPDT
>gi|672041400|ref|XP_008758943.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Rattus norvegicus] >gi|149059316|gb|EDM10323.1| rCG44727, isoform CRA_g [Rattus norvegicus]
MSIIMKPRSRSTSSLRTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVAEEESQPQTGVADDCCPDT
>gi|655839243|ref|XP_008260471.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Oryctolagus cuniculus] >gi|655839245|ref|XP_008260472.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Oryctolagus cuniculus]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEESQPEACVIDDYSPDT
>gi|641695229|ref|XP_008160064.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Eptesicus fuscus]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEESQPEACVIDDHSPDT
>gi|568984463|ref|XP_006517710.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Mus musculus] >gi|37256027|gb|AAQ90406.1| cAMP-specific phosphodiesterase PDE4D9 [Mus musculus] >gi|187465739|emb|CAQ51656.1| phosphodiesterase 4D, cAMP specific [Mus musculus]
MSIIMKPRSRSTSSLRTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVAEEESQPETCVPDDCCPDT
>gi|560908213|ref|XP_006180424.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Camelus ferus]
MAFVWDPRGATVPGPSARVKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLVLQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPEDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEENQPEAHVIEDHSPDT
>gi|556740076|ref|XP_005965586.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Pantholops hodgsonii]
MSIIMKPRSRSTSSLRTSEGVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCT
QDSEATETPLDEQVEEEAVAGGEGAQPEACVAGEPSPGT
>gi|532027744|ref|XP_005356839.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Microtus ochrogaster]
MSIVMKPRSRSTSSLRTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVAEEEASQPETCAIDDGCPDT
>gi|525026537|ref|XP_005060714.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Ficedula albicollis]
MAFLWDPSGAYMPRPSPRNKMRFRFLKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITEEAYQKLASETME
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSF
SDSKTLCTQDSESTEIPLDEQVGEEVEEEENQTAEPCMVEEHSPDT
>gi|524922716|ref|XP_005065612.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Mesocricetus auratus]
MSIIMKPRSRSTSSLRTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVAEEEGNQPETCVIEDCCPDT
>gi|513229260|ref|XP_004937313.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Gallus gallus]
MAFLWDPFGAYIPRPSPRNKMRFRFLKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTVFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVGEEVEEEENQTESCVVDHSPDT
>gi|511840335|ref|XP_004744672.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X11 [Mustela putorius furo] >gi|511942080|ref|XP_004789814.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X11 [Mustela putorius furo]
MAFLWDPQGVTVPGPSPRAKTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEETVGEEEDSQPEPCGIEDHSPDT
>gi|511840333|ref|XP_004744671.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Mustela putorius furo] >gi|511942078|ref|XP_004789813.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Mustela putorius furo]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEETVGEEEDSQPEPCGIEDHSPDT
>gi|472378760|ref|XP_004408798.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 5 [Odobenus rosmarus divergens]
MAFLWDPQGVTVPGPSPRAKTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEETVGEEEDSQPAACVIEDHSPDT
>gi|471392358|ref|XP_004380555.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 6 [Trichechus manatus latirostris]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEERQPEACVIEDHSPDDT
>gi|403267509|ref|XP_003925871.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Saimiri boliviensis boliviensis]
MAFVWDPLGATVPGPSPRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|395510327|ref|XP_003759429.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Sarcophilus harrisii]
MSLPSSSEHLTLEKVARFRSAYIHGSPYAINKPIDIKQQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSPVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEEEAGPAESCAIEHEHSPDT
>gi|297294340|ref|XP_002804421.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Macaca mulatta]
MSIIMKPRSRSTSSLRTAEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEESHPEACVIDDRSPDT
>gi|664711485|ref|XP_008512718.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Equus przewalskii]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEESQPEACAAEDRSPDT
>gi|602680955|ref|XP_007453281.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Lipotes vexillifer]
MSIIMKPRSRSTSSLRTSEGVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQAEEEAVGEEERQPEACAIGDHSPDT
>gi|505801951|ref|XP_004608515.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Sorex araneus]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPTPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTDKFQFELTLEEDGESDTEKDCGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEECQPEASVVEDHSPDT
>gi|504142686|ref|XP_004583779.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Ochotona princeps]
MMHVNNFPFRRHSWICFDVDNGTSTGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQAEEEAVAEEESQPEACVIDDCSPDT
>gi|488534362|ref|XP_004458894.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 7 [Dasypus novemcinctus] >gi|488534364|ref|XP_004458895.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 8 [Dasypus novemcinctus]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQERELLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNYIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEESQPEACVIEDHSPDT
>gi|148686492|gb|EDL18439.1| phosphodiesterase 4D, cAMP specific, isoform CRA_a [Mus musculus]
RSRSTSSLRTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIH
GDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTR
HSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLT
NSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHA
DVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLA
VGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVH
CADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDI
LDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTE
IPLDEQVEEEAVAEEESQPETCVPDDCCPDT
>gi|641695235|ref|XP_008160067.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Eptesicus fuscus]
MASVQDLQGATVLGPSPRPKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLVTYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDHSPDT
>gi|617572961|ref|XP_007516965.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Erinaceus europaeus]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEAEGEEEECQPETCVVEEDHCPDT
>gi|560908217|ref|XP_006180426.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Camelus ferus]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLVLQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPEDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEENQPEAHVIEDHSPDT
>gi|525026527|ref|XP_005060709.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Ficedula albicollis]
MNKNTCSLRGKSKSVSEEALHHSTEDEESSQGMEPYLVRRLSSRNIQLPPLAFRQLEQADWDKKNDTETIPRPTTLPLRI
PPLIAITAAESSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGD
DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITEEAYQKLASETMEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNS
SIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADV
AYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVG
FKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA
DLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIP
LDEQVGEEVEEEENQTAEPCMVEEHSPDT
>gi|513229257|ref|XP_004937312.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Gallus gallus]
MSLPSNCEHLTLKKVARLRSAYIHGSPYAINKPIDIKQQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTVFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVGEEVEEEENQTESCVVDHSPDT
>gi|478497135|ref|XP_004422906.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 6 [Ceratotherium simum simum]
MSIIVKPRSRSTSSLRTTETACFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQSMVHCADLSNPTKPLQLYRQWTDRVMEEFFRQGDRERERGMEISPMCDKHSASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEESQPEACAIEDPSPDT
>gi|466035410|ref|XP_004275223.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 5 [Orcinus orca]
MSIVMKPRSRSTSSLRTSEGVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQAEEEAVGEEESQPEACAIGDHSPDT
>gi|426246451|ref|XP_004017007.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Ovis aries]
MAFVWDPRGASVPALSTRVKSRSRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDCQTLCTQDSEATRGAREEAREAGGGAQPEACVAGEPSPGT
>gi|390459922|ref|XP_003732387.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Callithrix jacchus] >gi|403267513|ref|XP_003925873.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Saimiri boliviensis boliviensis]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|8393932|ref|NP_058728.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 5 [Rattus norvegicus] >gi|2564962|gb|AAB81869.1| 3',5'-cyclic AMP phosphodiesterase [Rattus norvegicus] >gi|149059315|gb|EDM10322.1| rCG44727, isoform CRA_f [Rattus norvegicus]
MMHVNTFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVAEEESQPQTGVADDCCPDT
>gi|533157529|ref|XP_005392724.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Chinchilla lanigera]
MAFVWDPLGVTAPGSSPRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGQQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEVCVVDDCSPDT
>gi|513229245|ref|XP_004937309.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Gallus gallus]
MNKNTCTLHGRSKSVSEEVLHHRSEEEESFQGMEPYLVRRLSSRNIQLPPLAFRQLEQADWDKKNDTETISRPTTLPLRI
PPLIAITSAESSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGD
DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNS
SIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTVFQERDLLKTFKIPVDTLITYLMTLEDHYHADV
AYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVG
FKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA
DLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIP
LDEQVGEEVEEEENQTESCVVDHSPDT
>gi|478497133|ref|XP_004422905.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 5 [Ceratotherium simum simum]
MAFFWDLQGVPVTRPSLRAKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQSMVHCADLSNPTKPLQLYRQWTDRVMEEFFRQGDRERERGMEISPMCDKHSASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACAIEDPSPDT
>gi|471392351|ref|XP_004380553.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Trichechus manatus latirostris]
MAFVWELLGATVPGPSPRAKTRLHYAKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEERQPEACVIEDHSPDDT
>gi|466035415|ref|XP_004275224.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 6 [Orcinus orca]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQAEEEAVGEEESQPEACAIGDHSPDT
>gi|426384628|ref|XP_004058861.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 2 [Gorilla gorilla gorilla]
MAFVWDPLGATVPGQSTRAKSRLCFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|655839240|ref|XP_008260470.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Oryctolagus cuniculus]
MLSSAAKIYVLFKNHINLMTFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSI
ASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLE
TLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMH
SSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLE
DHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLE
NHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVL
QNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
DAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQD
SESTEIPLDEQVEEEAVGEEESQPEACVIDDYSPDT
>gi|637259359|ref|XP_008101084.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Anolis carolinensis]
MSIIMKPRSRSTSSLRTADITCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPKFGVKTDQEDILAKELEDVNKWGLQVFKIAEFSGNRPLTVIMYTIFQERELLKTFKIQPDMLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTDKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVGGEVEEEEEEEQSQTEHCVQEEHSPDT
>gi|612003356|ref|XP_007486425.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Monodelphis domestica]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSPVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEEEEDPAEPCAIENEHSPDT
>gi|586491550|ref|XP_006876230.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Chrysochloris asiatica]
MSLPSSCEYLTLGKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIEDHSPDT
>gi|556960551|ref|XP_005990766.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Latimeria chalumnae]
MSIIMKPRSRSTSSLRTTDYLCFDVDNGTSSGRSPLDPLASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATFTEEAYQKLATETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPAQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEEEDSLSKELEEVNKWGLNVFKVAEYSGNRPLTVVMYTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTNRVMEEFFRQGDRERERGMEISPMCDKHNASIEKTQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRPGQSEKFQFELTLEEDGESDTEKDSGSQVEEDNSFSDSKTLCT
QDSESTEIPLDEQGEEEEAPTEVCIEEDQTTDT
>gi|556960543|ref|XP_005990764.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Latimeria chalumnae]
MSLPTNSEYLTLEKIARYRSAYSHGSPYATNKPIDIKQRRLCFDVDNGTSSGRSPLDPLASPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATFTE
EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPA
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEEEDSLSKELEEVNKWGLNVFKVAEYSGNRPLTVVMYTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTNRVMEEFFRQGDRERERGMEISPMCDKHNASIEKT
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRPGQSEKFQFELTLEEDGESDTEK
DSGSQVEEDNSFSDSKTLCTQDSESTEIPLDEQGEEEEAPTEVCIEEDQTTDT
>gi|542162318|ref|XP_005489826.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Zonotrichia albicollis]
MSLPPSCDHLALGKVARLQNACTHGSPYAINKPIDIKQQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITE
EAYQKLASETMEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVEEEENQTAESCVVEEHSPDT
>gi|507934228|ref|XP_004678347.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Condylura cristata]
MSLPTSCEYLTLGKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRASSKRSPMCNQPSINKTTITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGHTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEACVIEDRSPDT
>gi|507615284|ref|XP_004623129.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Octodon degus]
MSLPSSCEHLTLGQVARFRSAYAHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGPQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGGGESQPEVCVTDECSPDT
>gi|345794112|ref|XP_003433854.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX5 [Canis lupus familiaris]
MAFLWDPQRFTVSGPSPRAKTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEETVGEEENSQPEACVIEDHSPDT
>gi|655839250|ref|XP_008260474.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Oryctolagus cuniculus]
MAFVWDPLGITVPGLSPRAKSRSRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEACVIDDYSPDT
>gi|655839237|ref|XP_008260469.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Oryctolagus cuniculus]
MIIFKFCFSKMSIVMKPRSRSTSSLRTTEATGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASET
LEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIP
VDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDT
SCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEACVIDDYSPDT
>gi|635028354|ref|XP_007971534.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Chlorocebus sabaeus] >gi|635028356|ref|XP_007971542.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Chlorocebus sabaeus]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEESQSEACVIDDRSPDT
>gi|617572953|ref|XP_007516963.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Erinaceus europaeus]
MAFVWDPQGATVSGSAPRAKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEAEGEEEECQPETCVVEEDHCPDT
>gi|586491546|ref|XP_006876228.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Chrysochloris asiatica]
MKRNTCDLLSRSKSASEETLHCSNDEEEPLRGMEPYLVRRLSCRSVQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEESQPEACVIEDHSPDT
>gi|585679878|ref|XP_006891576.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Elephantulus edwardii]
MKRNTCNLLSRSKSASEETLHSSNEEEDPLRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSDSENLQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEDAVGEAEESQPEVCIIEDHSPDT
>gi|557276359|ref|XP_006021324.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Alligator sinensis]
MAFLWDPLGISIPRPSPKNKMRFRFLKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTDQEDGLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASIEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVGEEVEEEESQTEPCVVEEDHSPDT
>gi|548511764|ref|XP_005694735.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Capra hircus]
MSIIVKPRSRSTSSLRTSEGVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCT
QDSEATRGGGGGGGGGGGGGPSRRPASPGSPPRARNGAQTPMPFVCVFCFFK
>gi|548511758|ref|XP_005694732.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Capra hircus]
MRQEVPAISSSCASATRHLAGSPEQAQRKCPPLATSAYCSSRGPPAPGLCTHSDLPLSPATPAHPSHMAFVWDPRGASVP
ALSTRVKSRSRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASD
IHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQ
TRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSS
LTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHY
HADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHH
LAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNM
VHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQ
DILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEA
TRGGGGGGGGGGGGGPSRRPASPGSPPRARNGAQTPMPFVCVFCFFK
>gi|532027738|ref|XP_005356836.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Microtus ochrogaster]
MLKPEGWDSSVKITTCNIGDKENIHDVHSANMMHVNSFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHS
QRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINK
ATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVE
IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMH
TIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADL
KTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNA
SVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGE
SDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEEASQPETCAIDDGCPDT
>gi|524922710|ref|XP_005065609.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Mesocricetus auratus]
MLKPESWDSSVKITTCNIGDKENLHDGGSANMMHVNTFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHS
QRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVE
IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMH
TIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADL
KTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNA
SVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGE
SDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEEGNQPETCVIEDCCPDT
>gi|488534368|ref|XP_004458897.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 10 [Dasypus novemcinctus]
MAFLWDPLGVSVPGPSPRTKARLRFAKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQERELLKTFKIPVD
TLITYLMTLEDHYHADVAYHNYIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEACVIEDHSPDT
>gi|426246453|ref|XP_004017008.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Ovis aries]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEAT
RGAREEAREAGGGAQPEACVAGEPSPGT
>gi|397514344|ref|XP_003827449.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Pan paniscus]
MAFVWDPLGATVPGPSTRTKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|655839218|ref|XP_008260461.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Oryctolagus cuniculus] >gi|655839221|ref|XP_008260462.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Oryctolagus cuniculus] >gi|655839224|ref|XP_008260463.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Oryctolagus cuniculus] >gi|655839229|ref|XP_008260464.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Oryctolagus cuniculus] >gi|655839231|ref|XP_008260466.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Oryctolagus cuniculus]
MERNTSDLLSQSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSAESSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEESQPEACVIDDYSPDT
>gi|1236959|gb|AAA97892.1| cAMP-specific phoshodiesterase HPDE4D3 variant [Homo sapiens]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNSQDRAPSKRSPTCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLRTQDSEST
EIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|584085526|ref|XP_006762501.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Myotis davidii]
MSLPTSCEYLTLEKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLVTYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRPGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEVPLDEQVEEEAVGDEEESQPEACVIDDHSPDT
>gi|32306513|ref|NP_006194.2| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D3 [Homo sapiens] >gi|332233633|ref|XP_003266008.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Nomascus leucogenys] >gi|397514346|ref|XP_003827450.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Pan paniscus] >gi|426384630|ref|XP_004058862.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 3 [Gorilla gorilla gorilla] >gi|530379370|ref|XP_005248595.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Homo sapiens] >gi|544437309|ref|XP_005557018.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Macaca fascicularis] >gi|347130|gb|AAA03592.1| phosphodiesterase [Homo sapiens]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|554526274|ref|XP_005857979.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Myotis brandtii]
MSLPTSCEYLTLGKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLVTYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEVPLDEQVEEEAVGDEEESQPEACVIDDHSPDT
>gi|533157527|ref|XP_005392723.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Chinchilla lanigera]
MSLPTSCEHLTLGKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGQQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEVCVVDDCSPDT
>gi|530639736|ref|XP_005306652.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Chrysemys picta bellii]
MSIVMKPRSRSTSSLRTADTICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVVMNTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCT
QDSESTEIPLDEQVGEEVEGEESHPEPCVLEEDHSPDT
>gi|507934224|ref|XP_004678345.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Condylura cristata]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFQGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRASSKRSPMCNQPSINKTTITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGHTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEESQPEACVIEDRSPDT
>gi|507615278|ref|XP_004623126.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Octodon degus]
MERDTCDSLSRSKSASEETLHSNNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIPRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDPEEGPQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGGGESQPEVCVTDECSPDT
>gi|504142680|ref|XP_004583776.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Ochotona princeps]
MSLPTSCEHLTLGKVAPFHSAFVQGSPYAINKPIAIKPQRRRFDVDNGTSTGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQPEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVAEEESQPEACVIDDCSPDT
>gi|297294338|ref|XP_002804420.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Macaca mulatta]
MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEESHPEACVIDDRSPDT
>gi|308387376|ref|NP_001184148.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D8 [Homo sapiens] >gi|119575383|gb|EAW54988.1| phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila), isoform CRA_g [Homo sapiens] >gi|261859340|dbj|BAI46192.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D [synthetic construct]
MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|641695221|ref|XP_008160059.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Eptesicus fuscus]
MKRNTSDLLSRNKSASEETLHSCNEEEDPLRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEEVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEESQPEACVIDDHSPDT
>gi|568984459|ref|XP_006517708.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Mus musculus]
MLKPECWDSSVKITTCNIGDEENINDGRAANMMHVNTFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHS
QRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVE
IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMH
TIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADL
KTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNA
SVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCE
SDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPETCVPDDCCPDT
>gi|37256004|gb|AAQ90405.1| cAMP-specific phosphodiesterase PDE4D9 [Rattus norvegicus]
MSIIMKPRSRSTSSLRTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMPQISGVKKL
MHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVAEEESQPQTGVADDCCPDT
>gi|625233416|ref|XP_007607855.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Cricetulus griseus]
MAFVWDPLGVTVPGPSPRTRTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVAEEEGNQPETCVIDDCCPDT
>gi|617572948|ref|XP_007516962.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Erinaceus europaeus]
MSLPTSCEYLTLGKVARFRSAYAHGSPYAINKPIDIKAQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEAEGEEEECQPETCVVEEDHCPDT
>gi|612003352|ref|XP_007486423.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Monodelphis domestica]
MAFVSDPLGASIPRLSPRAKMRMCFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSPVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEEEEDPAEPCAIENEHSPDT
>gi|585679885|ref|XP_006891578.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Elephantulus edwardii]
MSLPTSCEYLSLGKVARVRSAYVHGSPYATKPIDIKPQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESF
LYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEE
AYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQ
KEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQER
DLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSN
QFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVET
KKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQ
VGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKD
SGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEDAVGEAEESQPEVCIIEDHSPDT
>gi|545199146|ref|XP_005604251.1| PREDICTED: phosphodiesterase 4D, cAMP-specific isoform X2 [Equus caballus] >gi|664711479|ref|XP_008512715.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Equus przewalskii]
MSLPTSCEYLTLGKVTRFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACAAEDRSPDT
>gi|513229251|ref|XP_004937310.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Gallus gallus]
MGLLLLNWKVSEEVLHHRSEEEESFQGMEPYLVRRLSSRNIQLPPLAFRQLEQADWDKKNDTETISRPTTLPLRIPPLIA
ITSAESSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVT
PFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTVFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
GEEVEEEENQTESCVVDHSPDT
>gi|507649551|ref|XP_004703650.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Echinops telfairi]
MAFVWDPLGATVPAPSARSKTRLRFAKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRNSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEITLDEQVEEEAVGEETESQAEACVDEHSPDT
>gi|478497137|ref|XP_004422907.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 7 [Ceratotherium simum simum]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQSMV
HCADLSNPTKPLQLYRQWTDRVMEEFFRQGDRERERGMEISPMCDKHSASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDEQVEEEAVGEEEESQPEACAIEDPSPDT
>gi|440911564|gb|ELR61217.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D, partial [Bos mutus]
FDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLAS
LRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRML
NRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQED
VLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQ
STHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQ
NLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYR
QWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTI
PQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVADE
ESQPEACVIGDPSPDT
>gi|655839256|ref|XP_008260476.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Oryctolagus cuniculus]
MSLPSSCEHLTLGKVARFCSAFVQGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEACVIDDYSPDT
>gi|655839235|ref|XP_008260468.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Oryctolagus cuniculus]
MPALQASEETLHSSNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENLQRPTSLPLKILPLIAITSAES
SGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVL
ASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKR
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQ
EDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADV
VQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQL
YRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
TIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVG
EEESQPEACVIDDYSPDT
>gi|637259363|ref|XP_008101085.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Anolis carolinensis]
MNMMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIAS
DIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETL
QTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSS
SLTNSSIPKFGVKTDQEDILAKELEDVNKWGLQVFKIAEFSGNRPLTVIMYTIFQERELLKTFKIQPDMLITYLMTLEDH
YHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENH
HLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQN
MVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDA
QDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTDKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSE
STEIPLDEQVGGEVEEEEEEEQSQTEHCVQEEHSPDT
>gi|589937923|ref|XP_006981717.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Peromyscus maniculatus bairdii]
MLKPESWDSSVKITTCNIGDEENINDGRSANMMHVNTFPFRRHSWICFDVDNGTSAARSPLDPMTSPGSGLILQANFVHS
QRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVE
IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMH
TIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVD
HPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADL
KTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNA
SVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGE
SDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEEASQPETCVADDCCPDT
>gi|584085520|ref|XP_006762498.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Myotis davidii]
MQRNTSDLLSRNKSASEETLHSCNEEEDPLRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSEAENLQRPTSLPLKILP
LIAITSADSTGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRPGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEVPLD
EQVEEEAVGDEEESQPEACVIDDHSPDT
>gi|558097565|ref|XP_006081492.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Myotis lucifugus]
MQRNTSDLLSRNKSASEETLHSCNEEEDPLRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRXGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEVPLD
EQVEEEAVGDEEESQPEACVIDDHSPDT
>gi|554526270|ref|XP_005857977.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Myotis brandtii]
MQRNTSDLLSRNKSASEETLHSCNEEEDPLRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEVPLD
EQVEEEAVGDEEESQPEACVIDDHSPDT
>gi|545490736|ref|XP_005617478.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X15 [Canis lupus familiaris]
MKEGAKRRHFLLCMEMRQTFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIA
SDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLET
LQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHS
SSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLED
HYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLEN
HHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQ
NMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPD
AQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDS
ESTEIPLDEQVEEETVGEEENSQPEACVIEDHSPDT
>gi|528922138|ref|XP_005196190.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Bos taurus] >gi|528998078|ref|XP_005221562.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Bos taurus] >gi|555953884|ref|XP_005889111.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Bos mutus]
MSLPTSCEYLTLGKMARFRSPAYVHGSPYATNKPIDIKPQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRE
SFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLT
EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSP
TQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQ
ERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTE
KDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVADEESQPEACVIGDPSPDT
>gi|504142676|ref|XP_004583774.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Ochotona princeps]
MERDTPDLLSRSKSVSEETLHSGNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESESIQRPTSLPLKILP
LIAITSADSSGFDVDNGTSTGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDPEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQAEEEAVAEEESQPEACVIDDCSPDT
>gi|488534350|ref|XP_004458888.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Dasypus novemcinctus] >gi|488534352|ref|XP_004458889.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Dasypus novemcinctus] >gi|488534354|ref|XP_004458890.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Dasypus novemcinctus]
MERNTCDLLSRSKSVSEETLHSSNEEEDPLRGMEPYLVRRLSCRSVQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSADSTGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQERELLKTFKIPVDTLITYLMTLEDHYHADVAY
HNYIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEESQPEACVIEDHSPDT
>gi|545490724|ref|XP_005617473.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Canis lupus familiaris] >gi|545490726|ref|XP_005617474.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X11 [Canis lupus familiaris] >gi|545490728|ref|XP_005617475.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X12 [Canis lupus familiaris] >gi|545490730|ref|XP_005617476.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X13 [Canis lupus familiaris]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENIPRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEETVGEEENSQPEACVIEDHSPDT
>gi|164519089|ref|NP_001106805.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Rattus norvegicus] >gi|118772244|gb|ABL14108.1| cAMP-specific phosphodiesterase splice variant PDE4D8 [Rattus norvegicus]
MAFVWDPLGVTVPGPSPRTRTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPQTGVADDCCPDT
>gi|637259354|ref|XP_008101082.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Anolis carolinensis]
MAFVRDPLGTSVPTRLSPRNKRRFFLKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPKFGVKTDQEDILAKELEDVNKWGLQVFKIAEFSGNRPLTVIMYTIFQERELLKTFKIQPD
MLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTDKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVGGEVEEEEEEEQSQTEHCVQEEHSPDT
>gi|612003354|ref|XP_007486424.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Monodelphis domestica]
MSIIMKPRSRSTSSLRTTEAIGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSPVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEEEEDPAEPCAIENEHSPDT
>gi|594082612|ref|XP_006064901.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Bubalus bubalis]
MSLPTSCEYLTLGKMARFRSPAYVHGSPYATNKPIDIKPQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRE
SFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLT
EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSP
TQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQ
ERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTE
KDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQGEEEAVADDEESQPEACVIGDPSPDT
>gi|585151182|ref|XP_006728029.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Leptonychotes weddellii]
MSLPTGCEYLTLGKVARFRSPYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEEDSQPEACVIEDHSPDT
>gi|585151178|ref|XP_006728027.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Leptonychotes weddellii]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENIPRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEETVGEEEDSQPEACVIEDHSPDT
>gi|568984461|ref|XP_006517709.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Mus musculus]
MAFVWDPLGVAVPGPSPRTRTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPETCVPDDCCPDT
>gi|555953886|ref|XP_005889112.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Bos mutus]
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASET
LEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIP
VDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDT
SCSDSKTLCTQDSESTEIPLDEQVEEEAVADEESQPEACVIGDPSPDT
>gi|545490732|ref|XP_005617477.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X14 [Canis lupus familiaris]
MSLPTGCEYLTLGKVARFRSPYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEENSQPEACVIEDHSPDT
>gi|545490722|ref|XP_005617472.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Canis lupus familiaris]
MRREARKDRLVEEAEGAGAADPAVAAAELTGQASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLK
SESENIPRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSP
KSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEE
LDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQ
ISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDT
LITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELAL
MYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLD
NYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW
ETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCS
DSKTLCTQDSESTEIPLDEQVEEETVGEEENSQPEACVIEDHSPDT
>gi|533157521|ref|XP_005392720.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Chinchilla lanigera]
MERNTCDLLSRSKSASEETLHSSNEQEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIPRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGQQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEESQPEVCVVDDCSPDT
>gi|524922714|ref|XP_005065611.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Mesocricetus auratus]
MAFVWDPLGVTVPGPSPRTRTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVAEEEGNQPETCVIEDCCPDT
>gi|488534358|ref|XP_004458892.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 5 [Dasypus novemcinctus]
MSLPTSCEYLTLGKVSRFRSTYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQE
RELLKTFKIPVDTLITYLMTLEDHYHADVAYHNYIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEACVIEDHSPDT
>gi|472378758|ref|XP_004408797.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 4 [Odobenus rosmarus divergens]
MSLPTGCEYLTLGKVARFRSPYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEEDSQPAACVIEDHSPDT
>gi|472378754|ref|XP_004408795.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 2 [Odobenus rosmarus divergens]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENIPRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEETVGEEEDSQPAACVIEDHSPDT
>gi|335331685|ref|NP_001229433.1| phosphodiesterase 4D, cAMP-specific [Equus caballus] >gi|664711475|ref|XP_008512713.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Equus przewalskii]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRSVQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEESQPEACAAEDRSPDT
>gi|617572940|ref|XP_007516960.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Erinaceus europaeus]
MDKNTCDLLSRSKSASEETLHSNNEEEDLLRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSADSTGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEAEGEEEECQPETCVVEEDHCPDT
>gi|602680951|ref|XP_007453279.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Lipotes vexillifer]
MKRNTCDLLSRSKSASEETLHSTNEEEDPLRGMEPYIVRRLSCRSVQLPPLAFRQLEQADLKSELENTQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQAEEEAVGEEERQPEACAIGDHSPDT
>gi|591355780|ref|XP_007072194.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Chelonia mydas]
MAVVSHFRPPYGCPEPWSQPAPLRRAVVTALRPRNHTGRYGAPRAALHQALVTGQACRLREVPVPEQPTLSQSPGLVAVI
CIFVAVLLIAAGVVVVKLCHRREPAFRKLDEVPMRSRDSPDLGNCSTAPHVNAIKRRFSGTPLLPPLACRHVALSEASRP
PEPEGPRVVFTIEESRPSSSQEPGFLREAEGSWARHGEVPVPSPPWAAAPQSPLDLGVQRKVPWGAGLGRSDGGAAGQPT
GISGQAPALSSLEEKTRPLCSCGGAGACWRESYWRARDRMSLPTNCGSVALADCALMVCNGHLAGSSRAVNRPIDIVQKH
RRFDIENGLSSGRSPLDPQASPGSGLVLHGNVPHSQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQLL
ASLRTVRSNFAMLTQLQDRMASKRTSSSNPPSACKASLSEDACQKLAIETLGELDWCLDQLETLQTRHSVSEMASNKFKR
MLNRELSHLSETSRSGNQVSEYISSTFLDKQHEVEIPSPTPKEKVAEKSTCPMAQISGLKKLTHSSSFISSGIPRFGVKT
DQEGLLAKELEDTNKWGLDMFKITEYSGNRPLTVIMYSIFQERDLMKTFRIPADTFITFLMTLEDHYHADVAYHNNIHAA
DVVQSTHVLLSTPALEAVFTDLEVMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDVSVLENHHLAVGFRLLQEENC
DIFQHLSKKQRQSLRKMAIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPL
ELYRQWTDRIMVEFFRQGDREREKGMEISPMCDKLSASVEKSQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWY
QSMIPHSPSPSLPEEQDPEKGSGGEKFQFQLTLEEEGESDTEPEEAESPLEEDNSGSDSKTLATDDSESAEFERLSPGSA
GRDSPPPAHGGPLRNMLVKQKEALHFDNRRALERTLSQPDGGTSLGCPELGRSGSLVDGELGLDTEGKLTFLPLGT
>gi|332233631|ref|XP_003266007.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Nomascus leucogenys]
MAFVWDPLGATVPGPSTKAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|187465738|emb|CAQ51655.1| phosphodiesterase 4D, cAMP specific [Mus musculus]
HSAVPVDLLALSLQMAFVWDPLGVAVPGPSPRTRTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRR
ESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATI
TEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPS
PTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIF
QERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPG
VSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTM
VETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVE
KSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDT
EKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPETCVPDDCCPDT
>gi|359077381|ref|XP_003587559.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX3 [Bos taurus] >gi|555953880|ref|XP_005889109.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Bos mutus]
MKRNTCDLLSRSKSASEETLHSSHEEEDPLKGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVADEESQPEACVIGDPSPDT
>gi|657817657|ref|XP_008335839.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Cynoglossus semilaevis]
MNNPRSESSEDELSEVEEMTQEKRTTRLPVIQLMPRSVIPASPGGSPKNSPKDSPRGSPRNSPVLFRKLLMNRSINLQRR
RFTLAHTPSFDVENGLSVGRSPLDPQASPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKGPSRNSAAASDLHTEDMIV
TPFAQVLASLRTVRNNFAIITGQQDRPTSKTRSSGSNPPSMCKNSLAEEPHHQLSIETLDELDWCLEQLETLKTRHSVSE
MASNKFKRMLTRELTQLSETSRSGNQVSEFISSTFLEKQHDMDIMSPPAKEKDKKKRLMSQISGVKKATHSPSLVHSTIP
RFGVTSCQEGPLAKELEDINRWGLDIFKVSEYSGNRPLTVTMYTIFQERDLLKSFKIPADTFITFMMTLEDHYHADVAYH
NNIHAADVAQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLSKKQSQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIVHPLWETWADLVHPDAQEILDTLE
DNREWYQSMIPHSPLPTTVGQEKKTLSGEALAPGSTSTDKFQFEMTLEEEVESDSEIPAVKKGGCSQRRTPEISRTGSGS
GFTAKTHRFPKLTTTDSDRTFSLDCDENSAEERKTNEGVSGLTHVRLGT
>gi|641695225|ref|XP_008160062.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Eptesicus fuscus]
MSLPTSCEYLTLGKVARFRSAYVHGSPYATNKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRVAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLVTYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDHSPDT
>gi|637259326|ref|XP_008101076.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Anolis carolinensis] >gi|637259331|ref|XP_008101077.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Anolis carolinensis] >gi|637259335|ref|XP_008101078.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Anolis carolinensis] >gi|637259339|ref|XP_008101079.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Anolis carolinensis] >gi|637259343|ref|XP_008101080.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Anolis carolinensis]
MNSNSTLHIRSKSVSEEILYPHNEEEGALQGMEQYRVRRLSCRNLQLPPLAFRQLEQADWDRKGETESVSRPTSLSLRTL
PLIAITAAESSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDD
LIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSS
IPKFGVKTDQEDILAKELEDVNKWGLQVFKIAEFSGNRPLTVIMYTIFQERELLKTFKIQPDMLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNREWYQSTIPQSPSPAPDDQEEGRQGQTDKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPL
DEQVGGEVEEEEEEEQSQTEHCVQEEHSPDT
>gi|584085528|ref|XP_006762502.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Myotis davidii]
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASET
LEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIP
VDTLVTYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRPGQTEKFQFELTLEEDGESDTEKDSGSQVEEDT
SCSDSKTLCTQDSESTEVPLDEQVEEEAVGDEEESQPEACVIDDHSPDT
>gi|584085524|ref|XP_006762500.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Myotis davidii]
MATYKDGYFQASEETLHSCNEEEDPLRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSEAENLQRPTSLPLKILPLIAI
TSADSTGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTP
FAQVLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMAS
NKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFG
VKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAYHNNI
HAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQE
ENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPT
KPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNR
EWYQSTIPQSPSPAPDDQEEGRPGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEVPLDEQVE
EEAVGDEEESQPEACVIDDHSPDT
>gi|560908207|ref|XP_006180421.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Camelus ferus]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENVQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLVLQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPEDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEENQPEAHVIEDHSPDT
>gi|556740068|ref|XP_005965582.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Pantholops hodgsonii]
MKRNTCDLLSRSKSASEETLHSSHEEEDPLKGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEATETPLD
EQVEEEAVAGGEGAQPEACVAGEPSPGT
>gi|532027742|ref|XP_005356838.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Microtus ochrogaster]
MAFVWDPLGVTVAGPSPRTRTRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVAEEEASQPETCAIDDGCPDT
>gi|511840329|ref|XP_004744669.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Mustela putorius furo] >gi|511942074|ref|XP_004789811.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Mustela putorius furo]
MSLPTGCEYLTLEKVARFRSPYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEEDSQPEPCGIEDHSPDT
>gi|505801932|ref|XP_004608509.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Sorex araneus]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSDTENIQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPTPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDPEEGRQGQTDKFQFELTLEEDGESDTEKDCGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEECQPEASVVEDHSPDT
>gi|471392345|ref|XP_004380551.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Trichechus manatus latirostris]
MEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENIQRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPG
SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSK
RSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYI
SNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAE
LSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIL
AAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLAT
DMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERG
MEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEK
FQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEERQPEACVIEDHSPDDT
>gi|164519068|ref|NP_001106800.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Rattus norvegicus] >gi|22901890|gb|AAN10121.1| cAMP-specific phosphodiesterase PDE4D7 [Rattus norvegicus] >gi|149059309|gb|EDM10316.1| rCG44727, isoform CRA_a [Rattus norvegicus]
MERNTCDVLSRSKSASEETLHSCNDEEDPFRGMEPYLVRRLSSRSIQLPPLAFRQLEQTDLRSESENIPRPTSLPLKILP
LIAVTSADSTGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVAEEESQPQTGVADDCCPDT
>gi|612003349|ref|XP_007486422.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Monodelphis domestica]
MSSTICQSRIPKAQASEETLQSSCDEEDPLRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSADSSSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDD
LIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSS
IPRFGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSPVEEDTSCSDSKTLCTQDSESTEIPL
DEQVEEEAVGEEEEEEDPAEPCAIENEHSPDT
>gi|591357850|ref|XP_007053945.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Chelonia mydas]
MAFLWDPLGVSIPRLSPRNKMRYRFLKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVIMHTIFQERDLLKTFKIPAD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSF
SDSKTLCTQDSESTEIPLDEQVGEEVEGEESHTEPCVLEEDHSPDT
>gi|532027734|ref|XP_005356834.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Microtus ochrogaster]
MEKNTCDSLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSSRSIQLPPLAFRQLEQADLRSESENIPRPTSLPLKILP
LIAITSADSTGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVAEEEASQPETCAIDDGCPDT
>gi|524922712|ref|XP_005065610.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Mesocricetus auratus]
MSLPTSCEHLSLGKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEEGNQPETCVIEDCCPDT
>gi|507934222|ref|XP_004678344.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Condylura cristata]
MEAEGSSVPARAGNGEGSDGAGGTTLKAPKHLWRHEQHNQYPLRQPQFRLLHPHHHLPPPPSPSPQPQPQPPLQPPPPPP
LPPPPPPPGAARGRYASSGATSRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
SGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRASSKRSPMCNQPSINKTTITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDQEEGRQGHTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEACV
IEDRSPDT
>gi|507615276|ref|XP_004623125.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Octodon degus]
MEAEGSDTPGQAGTGEGNDGAGGAALKAPKHLWRQEQHHQYPLRQPQFRLLHPHHHLPAPPPPSPQPQPQCPLQPPPPPP
LPPPPPPGAARGRYASSGATRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAG
RSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEM
SRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVN
KWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSL
RKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEF
FRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
PEEGPQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGGGESQPEVCVTD
ECSPDT
>gi|505801939|ref|XP_004608511.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Sorex araneus]
MSLPASCEYLTLGKVARFRSAYVHGSPYATNKPIDIKPQRKRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPTPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTDKFQFELTLEEDGESDTEK
DCGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEECQPEASVVEDHSPDT
>gi|466035392|ref|XP_004275220.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Orcinus orca]
MKRNTCDLLSRSKSASEETLHSTNEEEDPLRGMEPYLVRRLSCRSVQLPPLAFRQLEKADLKSELENTQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQAEEEAVGEEESQPEACAIGDHSPDT
>gi|426246447|ref|XP_004017005.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Ovis aries]
MKRNTCDLLSRSKSASEETLHSSHEEEDPLKGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEATRGARE
EAREAGGGAQPEACVAGEPSPGT
>gi|669263970|ref|XP_008641149.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Corvus brachyrhynchos]
MAQQTSPDNLPVPEVDNTHSQNPWLNEDLVKTLRENLLQHEKSRTTRKSSPASPRLCPVISPRNSPRLLRRMFLNSNIPK
QRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
VTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITEDSVFNLDVEYLSSLKYCITALETKQTRHKLSG
YLNSPFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPRSPSPAPEEKEEGKQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDE
QVGEEVEEEENQTAEPCVVEEHSPDT
>gi|635028360|ref|XP_007971558.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Chlorocebus sabaeus]
MAFVWDPLGATVPGPSTGAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQSEACVIDDRSPDT
>gi|612003347|ref|XP_007486421.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Monodelphis domestica]
MEKSTSDLFPRRKSASEETLQSSCDEEDPLRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSADSSSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDD
LIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSS
IPRFGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSPVEEDTSCSDSKTLCTQDSESTEIPL
DEQVEEEAVGEEEEEEDPAEPCAIENEHSPDT
>gi|594655497|ref|XP_007176137.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Balaenoptera acutorostrata scammoni]
MKRNTCDLLSRSKSASEETLHSTNEEEDPLRGMEPYLVRRLSCRSVQLPPLAFRQLEQADLKSELENTQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQAEEEAVGEEEEESQPEACAIGAHSPDT
>gi|585679874|ref|XP_006891575.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Elephantulus edwardii]
MEAEGSSVPAPGSGDGGDDAGGTTLKAPKHLWRHEQQHQQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPPGAPRGRYASSGATGRVRHRGYSDTERYLYRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSS
GRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE
MSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDV
NKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTP
ALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQS
LRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEE
FFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPD
DQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEDAVGEAEESQPEVCI
IEDHSPDT
>gi|560908219|ref|XP_006180427.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Camelus ferus]
MSWPSSFQGLRRFDVDNGTSSGRSPLDPMTSPGSGLVLQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDD
LIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSS
IPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNREWYQSTIPQSPSPAPEDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPL
DEQVEEEAVGEEEENQPEAHVIEDHSPDT
>gi|560908211|ref|XP_006180423.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Camelus ferus]
MSLPTGCEYLTPGKVARSRSSVYVHGSPYAINKPIDIKPQRRRFDVDNGTSSGRSPLDPMTSPGSGLVLQANFVHSQRRE
SFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATIT
EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSP
TQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQ
ERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPEDQEEGRQGQTEKFQFELTLEEDGESDTE
KDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEENQPEAHVIEDHSPDT
>gi|532027740|ref|XP_005356837.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Microtus ochrogaster]
MSLPTGCEYLRLGKVARFRSAYVHGSPCAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEEASQPETCAIDDGCPDT
>gi|511840317|ref|XP_004744663.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Mustela putorius furo] >gi|511840319|ref|XP_004744664.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Mustela putorius furo] >gi|511840321|ref|XP_004744665.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Mustela putorius furo] >gi|511840323|ref|XP_004744666.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Mustela putorius furo] >gi|511840325|ref|XP_004744667.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Mustela putorius furo] >gi|511942062|ref|XP_004789805.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Mustela putorius furo] >gi|511942064|ref|XP_004789806.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Mustela putorius furo] >gi|511942066|ref|XP_004789807.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Mustela putorius furo] >gi|511942068|ref|XP_004789808.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Mustela putorius furo] >gi|511942070|ref|XP_004789809.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Mustela putorius furo]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENIPRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEETVGEEEDSQPEPCGIEDHSPDT
>gi|505801942|ref|XP_004608512.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Sorex araneus]
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASET
LEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPTPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIP
VDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTDKFQFELTLEEDGESDTEKDCGSQVEEDT
SCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEECQPEASVVEDHSPDT
>gi|498942982|ref|XP_004542462.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Maylandia zebra]
MNDLCSESSEEEQSEVDETPREQKLSRLPVIQLMSRTVGGSTGGSPKVSPKDSPRGSPRNSPLLFRKLLMNRSINLQRRR
FTLAHTPSFDVENGLSVGRSPLDPQASPNSGLARPTNFPHSQRRESFLYRSDSDFDLSPKGPSRNSSTASDLHTEDMIVT
PFAQVLASLRTVRSNFAVITGQQDRTASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCLEQLETLKTRHSVSEM
ASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKQHDMDIMSPPTKEKDKKKRPMSQISGVKKATHSPSLAPSTIPR
FGVNASQEGLLAKELEDINRWGIDIFKVSEYSGNRPLTVTMYTIFQERELLKSFKIPVDTFITFTMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDLSVLENHHLAVGFKLL
QEDNCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLELYRQWTDRIMVEFFTQGDREREKGMEISPMCDKHNASVEKNQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSMIPHSPSPHPEGQEEEEEQEDAFAGEASAHGRGSGSASADKFQFKLTLEEEGESDTESPPEEEEGHSSRRHEI
YRSDSASHVSRRLPKMLTSDSGRTFSLDSEKDMAEERETDEGVSGVPRFRIGT
>gi|472378752|ref|XP_004408794.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 1 [Odobenus rosmarus divergens]
MEAEGSSVPARAGSDEGSDGAGGATLKAPKHLWRQEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQPQCPLQPPPP
PPLPPPPPLPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNG
TSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRN
NFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTH
LSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKEL
EDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLL
STPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQ
RQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRI
MEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSP
APDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEEDSQPA
ACVIEDHSPDT
>gi|471392348|ref|XP_004380552.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Trichechus manatus latirostris]
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASET
LEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIP
VDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDT
SCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEERQPEACVIEDHSPDDT
>gi|591357846|ref|XP_007053943.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Chelonia mydas]
MSLPSSCEHLTLEKVARFRSAYIHGSPYAINKPIDIKQQKRRLSFLSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSIN
KATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEV
EIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVIM
HTIFQERDLLKTFKIPADTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDV
DHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLAD
LKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHN
ASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDG
ESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVEGEESHTEPCVLEEDHSPDT
>gi|556960546|ref|XP_005990765.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Latimeria chalumnae]
MAFPLDPMGASGPRLSPRNKMRLRFLKSYSFDVDNGTSSGRSPLDPLASPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATFTEEAYQKLATETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPAQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEEEDSLSKELEEVNKWGLNVFKVAEYSGNRPLTVVMYTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTNRVMEEFFRQGDRERERGMEISPMCDKHNASIEKTQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRPGQSEKFQFELTLEEDGESDTEKDSGSQVEEDNSF
SDSKTLCTQDSESTEIPLDEQGEEEEAPTEVCIEEDQTTDT
>gi|556740072|ref|XP_005965584.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Pantholops hodgsonii]
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASET
LEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIP
VDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDT
SCSDCQTLCTQDSEATETPLDEQVEEEAVAGGEGAQPEACVAGEPSPGT
>gi|554559062|ref|XP_005873929.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X6 [Myotis brandtii]
MAGHRTPQCQACLGLTGLVFRDACSMRRSGTALSFLLSEQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPP
GETEPSSCVVFTIGAQGTEQSHGPASSSFDLENALSRGRSAQDPQVGPGPGQVTQHSQRRESFLYRSESDYELLPKAMSR
NSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWC
LDQLETLQTRHSVGEMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGL
PHSASLSTATIPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQTFQIPVDTLATYLLTLEGHYH
ADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHL
AVGFKLLQAENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQQGDRER
ESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYLSKIPRSPGDPTSPEQGGLDRF
QFELTLEEAEEEEEEERMLAQEASESPDTDLLSPEASSDPGALCLDNQRTVGKPCMDHEGNVTAEPSGS
>gi|544437311|ref|XP_005557019.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Macaca fascicularis]
MAFVWDPLGATVPGPSTGAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|532094953|ref|XP_005333150.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Ictidomys tridecemlineatus]
MRRSRTSLSFLMTERARESADSGLAPMSPCGAVRRRFSGTPLLPPLSSRLGSPGEVESSACVVFTIDAQGVDKIHGLSPG
SFDLENGLSRGRTVLDPQSGPGLGRGAQAPAPHSQRRESFLYRSDSDYELSPKALSRNSSVASDLHGEDMIVTPFAQVLA
SLKTVRSNVAALAQGQVHGAVKQASVGNPPPSSQPPPPAEDSGQKLALETLEELDWCLDQLETLQTRHSVGEMASNKFKR
MLNRELTHLSESSRSGNQVSEYISRTFLDQQTEVELPRAAPEESQRPMSEISGLRGLPHSASLSAATVPRFGVQTDEEGQ
LAKELEDTNRWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLTLEGHYHADVAYHNSLHAADVAQS
AHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTSESGVLVCNESFIIPSHFTDEDLGTDSRGVSVGVAS
RGGKQGRWVLMLSPSLACPQVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLP
LYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQ
SKIPRSPVDTAVSSERGAPDRFQFQLALEEAEEEEEEEEEALEREPSGSPDT
>gi|527267750|ref|XP_005151989.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Melopsittacus undulatus]
MSLPASCEHLTQEKVARFQSANIHGSPYAINKPIDIKQQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKASLTE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPA
QKEKEKKKRPMSQISGVKKLMHSTSLTNSSIPRFGVKTEHEESLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHSDVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEVLAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLDLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKT
QVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSTIPQSPSPAADDQEESKQTQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEPVGEEVEEEENQTEPCVVEGHTPNT
>gi|507649539|ref|XP_004703647.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Echinops telfairi]
MKRNTCDLLSRRKSASEETLHSSTEEEDAVRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENIQRPTSLPLKMLP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRNSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDPEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEITLD
EQVEEEAVGEETESQAEACVDEHSPDT
>gi|504142674|ref|XP_004583773.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Ochotona princeps]
MEAEGSTAPARAASGEGSDGAGGATLKAPKHLWRHEQHHQYPLRQSQFRLLHAHHHLPPPPPPSPQPQGPLQPPPPPPLP
PPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSTG
RSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEM
SRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVN
KWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSL
RKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEF
FRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
PEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVAEEESQPEACVID
DCSPDT
>gi|478497131|ref|XP_004422904.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Ceratotherium simum simum]
MSLPTSCEYLTLGKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQSMVHCADLSNPTKPLQLYRQWTDRVMEEFFRQGDRERERGMEISPMCDKHSASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACAIEDPSPDT
>gi|466035403|ref|XP_004275222.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 4 [Orcinus orca]
MSLPTSCEFLTLGKVARFRSAAYVHGSPYATHKPIDIKPQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRE
SFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLT
EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSP
TQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQ
ERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTE
KDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVGEEESQPEACAIGDHSPDT
>gi|426246455|ref|XP_004017009.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 5 [Ovis aries]
MSLPTSCEYLTLGKMARFRSPAQVPGSPYATNKPIDIKPQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRE
SFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLT
EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSP
TQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQ
ERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTE
KDSGSQVEEDTSCSDCQTLCTQDSEATRGAREEAREAGGGAQPEACVAGEPSPGT
>gi|395818773|ref|XP_003782791.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Otolemur garnettii]
MSIVMKPRSRSTSSLRTTEAVGFDVDNGTSVGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPCPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEESQPEACVIDDHSPDT
>gi|22901886|gb|AAN10119.1| cAMP-specific phosphodiesterase PDE4D8 [Homo sapiens]
MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCGIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|259906420|ref|NP_001159371.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D7 [Homo sapiens] >gi|397514342|ref|XP_003827448.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Pan paniscus] >gi|22901884|gb|AAN10118.1| cAMP-specific phosphodiesterase PDE4D7 [Homo sapiens] >gi|32350924|gb|AAP75760.1| cAMP-specific phosphodiesterase variant PDE4D7 [Homo sapiens]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSAESSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|585151176|ref|XP_006728026.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Leptonychotes weddellii]
MEAEGSSVPARAGSDEGSDGAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQPQCPLQPPPP
PPLPPPPPLPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNG
TSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRN
NFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTH
LSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKEL
EDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLL
STPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQ
RQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRI
MEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSP
APDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEEDSQPE
ACVIEDHSPDT
>gi|548511760|ref|XP_005694733.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Capra hircus]
MKRNTCDLLSRSKSASEETLHSSHEEEDPLKGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENLQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEATRGGGG
GGGGGGGGGPSRRPASPGSPPRARNGAQTPMPFVCVFCFFK
>gi|512814534|ref|XP_004911042.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Xenopus (Silurana) tropicalis]
MISLTRFPIRRHSCICFDVENGLSSGRSPLESQASPGSGLVLQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSIASDL
HGEDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVSNKRSSGSNQPSACKPNLSEDAVQKLAIETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDKQHEVEIPTPVSKEKDKKKRPMSQISGVKKLTHSSSF
SNCSIPRFGVKTEQEVPLAKEVENINKWGLDIFKVAEYSGNRPLTVIMYSIFQERDLLKTFHIPVDTFITYMMTLEDHYH
SDVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLEIYRQWTDRIIVEFFHQGDREREKGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQE
ILDTLEDNREWYQSMIPQSPSPPPEEQDPDRGNAAGDKFQFELTLEEEGESDTEQEDTESPIDEENSDSKIHATDDSAQA
SDEAEQSSPVDLCMTVSSKLDHLEIPPKSTLTKQKKILNFDNLKLAGERTIQQKEVSSSHATPANSARQEGTGQAEICLD
QEGNITYLPLGT
>gi|478497127|ref|XP_004422902.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Ceratotherium simum simum]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQSMVHCADL
SNPTKPLQLYRQWTDRVMEEFFRQGDRERERGMEISPMCDKHSASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEESQPEACAIEDPSPDT
>gi|345794102|ref|XP_544349.3| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX8 [Canis lupus familiaris]
MEAEGSSVPARAGGDEGSDSAGGATLKAPKHLWRQEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPPGAARGRYTSSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
AGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEENSQPEAC
VIEDHSPDT
>gi|332233629|ref|XP_003266006.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 2 [Nomascus leucogenys]
MKRNTCDLLSRSKSASEETLHSSNDEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSAESSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|297294336|ref|XP_001101097.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Macaca mulatta]
MAFVWDPLGATVPGPSTGAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESHPEACVIDDRSPDT
>gi|637259350|ref|XP_008101081.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Anolis carolinensis]
MSLPSSCEHLTLEKVARFRSAFIHGSPYAINKPIDIKQQRRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTDQEDILAKELEDVNKWGLQVFKIAEFSGNRPLTVIMYTIFQE
RELLKTFKIQPDMLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTDKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVGGEVEEEEEEEQSQTEHCVQEEHSPDT
>gi|591357844|ref|XP_007053942.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Chelonia mydas]
MSLPSSCEHLTLEKVARFRSAYIHGSPYAINKPIDIKQQKRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPADTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVEGEESHTEPCVLEEDHSPDT
>gi|586491544|ref|XP_006876227.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Chrysochloris asiatica]
MEAEGSNVPVPGSSEGGDGAGGATLKAPKHLWRHEQQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRNMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
AGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLAT
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEAC
VIEDHSPDT
>gi|544437295|ref|XP_005557011.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Macaca fascicularis] >gi|544437297|ref|XP_005557012.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Macaca fascicularis]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFHGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|533157519|ref|XP_005392719.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Chinchilla lanigera]
MEAEGSSMPGQAGSGEGSDAGGATLKAPKHLWRQEQHHQYPLRQPQFRLLHPHHHLPAPPPPSPQPQPQCPLQPPPPPPL
PPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAG
RSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEM
SRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVN
KWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSL
RKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEF
FRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
QEEGQQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEVCVVD
DCSPDT
>gi|527267757|ref|XP_005151992.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Melopsittacus undulatus]
MAFLWDPFGAYIPRPSPRNKMRFRFLKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKASLTEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPAQKEKEKKKRPMS
QISGVKKLMHSTSLTNSSIPRFGVKTEHEESLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHSDVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLDLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVHPL
WETWADLVHPDAQEILDTLEDNREWYQSTIPQSPSPAADDQEESKQTQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEPVGEEVEEEENQTEPCVVEGHTPNT
>gi|524922706|ref|XP_005065607.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Mesocricetus auratus]
MERDTCDLLSRSKSASEETLHSSNEEEDPFHGMEPYLVRRLSSRSIQLPPLAFRQLEQTDLRSESENIPRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVAEEEGNQPETCVIEDCCPDT
>gi|512809758|ref|XP_004910404.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Xenopus (Silurana) tropicalis]
MSIILKPRSRSTSSLRTTDGLCFDVDNGTTSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYELSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKLAGETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKKL
MHSSSLTNSNIPRFGVKSENEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDDQVDEEESQLEPNSIEQAHSPDT
>gi|23510241|ref|NP_035186.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Mus musculus] >gi|57015302|sp|Q01063.2|PDE4D_MOUSE RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D; AltName: Full=DPDE3 [Mus musculus] >gi|22901888|gb|AAN10120.1| cAMP-specific phosphodiesterase PDE4D7 [Mus musculus] >gi|124297621|gb|AAI32108.1| Phosphodiesterase 4D, cAMP specific [Mus musculus] >gi|124297623|gb|AAI32110.1| Phosphodiesterase 4D, cAMP specific [Mus musculus] >gi|148686493|gb|EDL18440.1| phosphodiesterase 4D, cAMP specific, isoform CRA_b [Mus musculus] >gi|148686494|gb|EDL18441.1| phosphodiesterase 4D, cAMP specific, isoform CRA_b [Mus musculus]
MERDTCDVLSRSKSASEETLHSCNEEEDPFRGMEPYLVRRLSSRSIQLPPLAFRQLEQADLRSESENIPRPTSLPLKILP
LIAVTSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVAEEESQPETCVPDDCCPDT
>gi|169742982|gb|ACA66114.1| cAMP-specific phosphodiesterase 4D isoform 11 [Mus musculus]
MSLPTSCEHLGLGKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPETCVPDDCCPDT
>gi|635028358|ref|XP_007971551.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Chlorocebus sabaeus]
MYLSCALSTLTEGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGD
DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNS
SIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADV
AYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVG
FKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA
DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIP
LDEQVEEEAVGEEEESQSEACVIDDRSPDT
>gi|635028346|ref|XP_007971512.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Chlorocebus sabaeus]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFHGMEPYLVPRLSCRNIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSI
PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEESQSEACVIDDRSPDT
>gi|589937925|ref|XP_006981718.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Peromyscus maniculatus bairdii]
MSLPTSCEHLSLGKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSAARSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEEASQPETCVADDCCPDT
>gi|558129635|ref|XP_006089853.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3 [Myotis lucifugus]
MTAKNSSKELTASEPEVCIKTFKEQMHLELELPRPPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTLC
FDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLA
SLRSVRNNFTLLTNLQCLAQSRQAPIGGDSAMDSLPPLQPNYMSVCLFAEEPYQKLAMETLEELDWCLDQLETIQTYRSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNN
TSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSD
VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAV
GFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHC
ADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDIL
DTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPESRDSLGET
DVDNAAEDKSPVDT
>gi|507649547|ref|XP_004703649.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Echinops telfairi]
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASET
LEELDWCLDQLETLQTRNSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIP
VDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDT
SCSDSKTLCTQDSESTEITLDEQVEEEAVGEETESQAEACVDEHSPDT
>gi|466035386|ref|XP_004275219.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Orcinus orca]
MEAEGSSLPARAGSGEGSDGTGGAALKAPKHLWRQEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPPCPVQPPPAPLPP
PPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGR
SPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAAL
TNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMS
RSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNK
WGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPAL
EAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLR
KMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFF
RQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQ
EEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVGEEESQPEACAIGD
HSPDT
>gi|355691329|gb|EHH26514.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D, partial [Macaca mulatta] >gi|355749936|gb|EHH54274.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D, partial [Macaca fascicularis]
NSFSFLYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVT
PFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESQPEACVIDDRSPDT
>gi|635028350|ref|XP_007971527.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Chlorocebus sabaeus]
MSLPSSCEYLTLGKVARFRSAYVHGSPYAINMPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQSEACVIDDRSPDT
>gi|511840315|ref|XP_004744662.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Mustela putorius furo] >gi|511942060|ref|XP_004789804.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Mustela putorius furo]
MEAEGSSVPARAGSDEGSDGAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPSSPQPQPQCPLQPPPPPP
LPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
AGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEEDSQPEPC
GIEDHSPDT
>gi|449514304|ref|XP_002187853.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Taeniopygia guttata]
MDRASYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITVNPQTKLYQKL
ASETMEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEK
KKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKT
FKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLIN
TNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTS
SGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFID
YIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQV
EEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVEEDENQTAEPCMVEEHSPDT
>gi|297487632|ref|XP_002696361.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX1 [Bos taurus] >gi|296475830|tpg|DAA17945.1| TPA: phosphodiesterase 4D, cAMP-specific [Bos taurus]
MEAEGSSVPARAGSGEGSDGAGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQCPLQPPPPPLPP
PPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVRTSHKPGLKVSQCVWPSSMDGLRNFDVDNGTSSG
RSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
LTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEM
SRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVN
KWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSL
RKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEF
FRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
QEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVADEESQPEACVIG
DPSPDT
>gi|194676385|ref|XP_588063.3| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX1 [Bos taurus]
MEAEGSSVPARAGSGEGSDGAGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQCPLQPPPPPLPP
PPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRNFDVDNGTSSG
RSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
LTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEM
SRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVN
KWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSL
RKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEF
FRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
QEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVADEESQPEACVIG
DPSPDT
>gi|544437301|ref|XP_005557014.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Macaca fascicularis]
MDTKASEETLHSSNEEEDPFHGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILPLIAITSADSS
GFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLA
SLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRM
LNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQE
DVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVV
QSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIF
QNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLY
RQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQST
IPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGE
EEESQPEACVIDDRSPDT
>gi|530639732|ref|XP_005306650.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Chrysemys picta bellii]
MSLPSSCEHLTLEKVARFRSAYIHGSPYAINKPIDIKQQKRRISFFSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSIN
KATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEV
EIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVVM
NTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDV
DHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLAD
LKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHN
ASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDG
ESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVEGEESHPEPCVLEEDHSPDT
>gi|57015263|sp|P14270.4|PDE4D_RAT RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D; AltName: Full=DPDE3 [Rattus norvegicus] >gi|2625100|gb|AAB95266.1| cAMP-specific phosphodiesterase [Rattus norvegicus]
MEAEGSSVPARAGSHEGSDSSGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQLQPPPPPPLPPP
PPPPGATRGRYASSGASRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSP
LDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTN
LQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRS
GNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWG
LHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM
AIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQ
GDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQED
GRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPQTGVADDCC
PDT
>gi|403267511|ref|XP_003925872.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 3 [Saimiri boliviensis boliviensis]
MEAEGSSKPARAGSGEGSDSASGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQPQCPLHPPPP
PPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVDTGHRPGLKKSRMSWPSSFQGLRRFDVDNG
TSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRN
NFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTH
LSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKEL
EDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLL
STPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQ
RQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRI
MEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSP
APDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPE
ACVIDDRSPDT
>gi|334325192|ref|XP_003340617.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Monodelphis domestica]
MEAEGSSVPAQAGSGGEGSDGSSVGATLKAPKHLWRHEQHYQYQLRQHQFRLLHPHHHHSPPPPPPQSQSQPQPQSQSQP
QPQPQCPLQQQQPPPPPPPPLPPPPPPPPGATRGRYGGSSGSSRVRHRGYSDTERYLYCRAMDRASYAVETGHRPGLKKS
RMSWPSSFQGLRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGD
DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNS
SIPRFGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADV
AYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVG
FKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCA
DLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSPVEEDTSCSDSKTLCTQDSESTEIP
LDEQVEEEAVGEEEEEEDPAEPCAIENEHSPDT
>gi|296194533|ref|XP_002744978.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Callithrix jacchus]
MEAEGSSKPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYQLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVDTGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
AGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEAC
VIDDRSPDT
>gi|625239752|ref|XP_007611109.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Cricetulus griseus]
MRWRGTALSLLSERVLEPVDSGAVPASPLGEGVIHRRFSGTLLLPPLYSCLGSSGEAESGAHVVFTTGTRGTERNQSPAQ
SSFDLENGFASSRGPLDPQSGRVLQPPGQHGLRRESFLYRSESDHEPSPKAVSRNSSVASDVHGEDMIVTPFAQVLASLR
TVRSNVAALAHGPGRQPLPGTPPCSSQPAAPSEDAGLQLARETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELT
HLSETSRSGNQVSEYISQTFLDQQAEVELPRLPREDTRPMSQISALRGPRPTGLPTAAVPRFGVQTDQEGQLAKELEDTN
KWGLDVFKVAQLSGNRPLTAIMFSVLQERDLLKTFRIPADTLLAYLLMLEGHYHADVAYHNSVHAADVAQSAHVLLGTPA
LEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDVSVLENHHLAVGFKLLQAENCDIFRNLSTKQRLSL
RRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLQLYRQWTNRIMAEF
FQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNREWYQSRIPCSPSHTMGQ
HCSGPDKFQFELTLEEAEEEENEGQSPLLPGACGGADKQGSPVALERVERHRFLAGVAEHPGDKLFWSFCGASAAGQLAP
TRRSRSPTNEAFLLPRSSALRGSPALPPEPALASGTPWLPARPLPLTSRARLHRSPAPGFAGRQRGLQGPEPPPPPAARS
RPWGPVTSAVARVSAVGVASARSGQGERARA
>gi|544437303|ref|XP_005557015.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Macaca fascicularis]
MEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPG
SGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSK
RSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFI
SNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAE
LSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIL
AAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLAT
DMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERG
MEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEK
FQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|542205052|ref|XP_005476146.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Oreochromis niloticus]
MNDLCSESSEEEQSEVDETPREQKLSRLPVIQLMSRTVGGSTGGSPKVSPKDSPRGSPRNSPLLFRKLLMNRSINLQRRR
FTLAHTPSFDVENGLSVGRSPLDPQASPNSGLARPTNFPHSQRRESFLYRSDSDFDLSPKGPSRNSSTASDLEESLKHWE
VNWLSSRHTEDMIVTPFAQVLASLRTVRSNFAVITGQQDRTASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCL
EQLETLKTRHSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKQHDMDIMSPPTKEKDKKKRPMSQISGVK
KATHSPSLAPSTIPRFGVNASQEGLLAKELEDINRWGIDIFKVSEYSGNRPLTVTMYTIFQERDLLKSFKIPVDTFITFM
MTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDL
SVLENHHLAVGFKLLQEDNCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDR
IQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDREREKGMEISPMCDKHNASVEKNQVGFIDYIVHPLWETWAD
LVHPDAQDILDTLEDNREWYQSMIPHSPSPHPEGQEEEEEEEDTFAGEASAHCRGSGSASADKFQFKLTLEEEGESDTES
PPEEEEGQSSSRRHEIYRSDSASPASRRLPKMLTSDSGRTFSLDSEKDMAEERETDEGVSGVPRFRIGT
>gi|530639740|ref|XP_005306654.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Chrysemys picta bellii]
MSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQV
LASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFK
RMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTE
QEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVVMNTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAAD
VVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCD
IFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQ
LYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ
STIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVE
GEESHPEPCVLEEDHSPDT
>gi|530379368|ref|XP_005248594.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Homo sapiens] >gi|544437305|ref|XP_005557016.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Macaca fascicularis]
MSLPSSCEYLTLGKVARFRSAYVHGSPYAINMPIDIKPQRRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|164519066|ref|NP_001106799.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Rattus norvegicus] >gi|149059312|gb|EDM10319.1| rCG44727, isoform CRA_c [Rattus norvegicus]
MEAEGSSVPARAGSDEGSDSSGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQLQPPPPPPLPPP
PPPPGATRGRYASSGASRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSP
LDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTN
LQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRS
GNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWG
LHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM
AIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQ
GDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQED
GRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPQTGVADDCC
PDT
>gi|478497125|ref|XP_004422901.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Ceratotherium simum simum]
MEAEGSSVPTRAGSGEGSDGAGGATLKAPKHLWRHEQHHQYPLRQPQVRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPGATRGRYASSGTTGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSS
GRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSE
MSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDV
NKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTP
ALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQS
LRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQSMVHCADLSNPTKPLQLYRQWTDRVMEE
FFRQGDRERERGMEISPMCDKHSASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPD
DQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACA
IEDPSPDT
>gi|524922704|ref|XP_005065606.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Mesocricetus auratus]
MEAEGSRVPARTGSGEGSDGAAGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQLQPPPPPPLPPP
PPPPGATRGRYASSGASRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSP
LDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTN
LQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRS
GNQVSEYISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWG
LHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM
VIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQ
GDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEE
GRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEEGNQPETCVIEDC
CPDT
>gi|568984455|ref|XP_006517706.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Mus musculus]
MEAEGSSVPARAVSEEGNDSAGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQLQPPPPPPLPPP
PPPPGATRGRYASSGASRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSP
LDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTN
LQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRS
GNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWG
LHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM
VIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQ
GDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEE
GRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPETCVPDDCC
PDT
>gi|532027732|ref|XP_005356833.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Microtus ochrogaster]
MEAEGSSVPVRAGSGEGSDGTGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQLQPPPPPPLPPP
PPPPGATRGRYASSGASRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSP
LDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTN
LQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRS
GNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWG
LHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM
VIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQ
GDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEE
GRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEEASQPETCAIDDG
CPDT
>gi|530639734|ref|XP_005306651.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Chrysemys picta bellii]
MSLPSSCEHLTLEKVARFRSAYIHGSPYAINKPIDIKQQKRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSINKATITE
EAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVVMNTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVEGEESHPEPCVLEEDHSPDT
>gi|514479141|ref|XP_005007999.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4 [Cavia porcellus]
MTAKNSSKELTASEPDVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTLC
FDVENGPSPGRSPLDPQAGSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLA
SLRSVRNNFTLLQQQSTIGDAEEGPVGTPLTSNRLTPAEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRM
LNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTE
NEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFITYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCD
IFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVASSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLE
LYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQ
SMIPQSPSPPLEERSRDCQGLMEKFQFELTLEEEDSEGREKDGEGHGYFSSTKTLCVIDPESEDPLGESDVDTATEDKSP
TDT
>gi|512809762|ref|XP_004910405.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Xenopus (Silurana) tropicalis]
MMHVNNFPFRRHSWICFDVDNGTTSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYELSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKLAGETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKKLMHSSSL
TNSNIPRFGVKSENEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDEQEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSEST
EIPLDDQVDEEESQLEPNSIEQAHSPDT
>gi|635028344|ref|XP_007971506.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Chlorocebus sabaeus]
MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPTGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
AGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQSEAC
VIDDRSPDT
>gi|573877442|ref|XP_006626969.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Lepisosteus oculatus]
MVRRLSSRNLQLPPLAFRQAEQYEWDRKPESEHIQRPTTLPLRTPPLIAITSADISSFDVDNGTSSGRSPLDPMTSPGSG
LILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNVQQDRASNKR
SPMCNQPPISKSSFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYIS
NTFLDKQHEVEMPSLTQKEKDKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKTDTEDSLAKELEDVNKWGLNVFKVTEF
SGNRPLTVIMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHGDVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEILA
AIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATD
MSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGM
EISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPGDPEEGQQGTADKF
QFELTLEEDGESDTEKDSGSQAEEEEEEEEEEEEEENSCSDSKTLCTQDSESTEIPLDEQAEEEEEEDGVSVEPCVVVEE
DQPADT
>gi|530639738|ref|XP_005306653.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Chrysemys picta bellii]
MAGQPRTFWLWRQALLFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSL
TNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVVMNTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHL
AVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
ILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSEST
EIPLDEQVGEEVEGEESHPEPCVLEEDHSPDT
>gi|512814522|ref|XP_004911040.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Xenopus (Silurana) tropicalis]
MRRSRTMSFLTNERSRETYDLNAYPIVPSLSAIKRRFSGTPQLPPLYHRQGNDNSKPEPESGRVVFTIEEIDLGTYDDPP
SDYLSFDVENGLSSGRSPLESQASPGSGLVLQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFA
QVLASLRTVRSNFAMLTHLQDRVSNKRSSGSNQPSACKPNLSEDAVQKLAIETLEELDWCLDQLETLQTRHSVSEMASNK
FKRMLNRELTHLSETSRSGNQVSEYISSTFLDKQHEVEIPTPVSKEKDKKKRPMSQISGVKKLTHSSSFSNCSIPRFGVK
TEQEVPLAKEVENINKWGLDIFKVAEYSGNRPLTVIMYSIFQERDLLKTFHIPVDTFITYMMTLEDHYHSDVAYHNNIHA
ADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEEN
CDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LEIYRQWTDRIIVEFFHQGDREREKGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREW
YQSMIPQSPSPPPEEQDPDRGNAAGDKFQFELTLEEEGESDTEQEDTESPIDEENSDSKIHATDDSAQASDEAEQSSPVD
LCMTVSSKLDHLEIPPKSTLTKQKKILNFDNLKLAGERTIQQKEVSSSHATPANSARQEGTGQAEICLDQEGNITYLPLG
T
>gi|544437293|ref|XP_005557010.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Macaca fascicularis]
MEAEGSSAPARAGSGEGSDSAGGSTLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPTGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
AGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEAC
VIDDRSPDT
>gi|543718414|ref|XP_005516184.1| PREDICTED: LOW QUALITY PROTEIN: phosphodiesterase 4D, cAMP-specific [Columba livia]
MSIVMKPRSRSTSSLRTADTMCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLEQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSATSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSENRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKWQVSFIEYIVHPLWETWADLV
HPDAQDILDTLENNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVGEEVEEEENRAXPCVVEDHCPDT
>gi|157277988|ref|NP_001098101.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D4 [Homo sapiens] >gi|12644392|sp|Q08499.2|PDE4D_HUMAN RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D; AltName: Full=DPDE3; AltName: Full=PDE43 [Homo sapiens] >gi|2623739|gb|AAC00042.1| cyclic AMP phosphodiesterase [Homo sapiens] >gi|119575384|gb|EAW54989.1| phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila), isoform CRA_h [Homo sapiens]
MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
AGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEAC
VIDDRSPDT
>gi|395818771|ref|XP_003782790.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 1 [Otolemur garnettii]
MEAEGSSVPARAGSAEGSDSAGGATLKAPKHLWRQEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPPGAARGRYASSGAGGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
VGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEYISNTFLDKQHEVEIPCPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEACV
IDDHSPDT
>gi|589937921|ref|XP_006981716.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Peromyscus maniculatus bairdii]
MEAEGSSVPARAGSGEGSDGAGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQLQPPPPPPLPPP
PPPPGATRGRYASSGASRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAARSP
LDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTN
LQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRS
GNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWG
LHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM
VIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQ
GDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEE
GRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEEASQPETCVADDC
CPDT
>gi|551486743|ref|XP_005794951.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Xiphophorus maculatus]
MSIILKPRSRSTSSLKNTEGICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPICNPPPITKTTFTEEAYQKLATETLEELDWCLD
QLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVK
KLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYL
MTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDS
SVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDR
IQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWAD
LVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEENS
CTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGDAEEEGETPCSEPCVADEEVAEDEEEKKSPDT
>gi|444726631|gb|ELW67155.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Tupaia chinensis]
MASSLLPLLLLNLLMLTKPSDFFTSRVTPAAPGGAGDGRLHRNPGVVVAVCVLLSIVVVGSVIMAVRRCQQGPFNFQKMD
EVSMLSNRLGLPGEAEPSPGVVFTIGARTADKNHSPAPGSTYGVDSSSLSSPPLASGRIGGCRYSWACVHGFSSSSLLSR
LPLFWRMETPGVSEGAEKPRGLSCARSRQGVVRTPKHLWRQPRRPIRIQQRFHSDPNKSASLYERDWSSRPGLGKSRRSW
PISFPRRFDLENGLSCGRNTLDPQSGPGLGRGSQAPGQHSQRRESFLYRSDSDYELSPKAMSRNSSAASDLHGEDLIVTP
FAQVLASLRTVRSNVAALAHLQGRGVAKYAEGVAKKDGGGAWGDGQPRSFQAEGLEDLGGAWQSPGVELGQVSAETPPSS
SSSPPPTVQADAELGIDAPVGLNRELTHLSETSRSGNQVSEYISRTFLDQPTEMELPRETPPEPPRPLSEISGLRGLPRG
PSLSAATVPRFGVQTDQEAQLAKELEDTNRWGLDVFKVAELSGNHPLTAVMFSIFRERDLLKTFQIPADTLVTYLLMLEG
HYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLEN
HHLAVGFKLLQAENCDIFRNLSAKQRLSLRRMVIDMNHHLAVGFKLLQAENCDIFRNLSAKQRLSLRRMVIDMVLATDMS
KHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERDSGLDI
SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPADLTSPEWSSPDRFQFELTL
EEAEEEEEEEEEGEEEEASLGQETSESPDTELLSSEASPDPEAPPLGNQRTLGKTCVDREGNMVTESLGT
>gi|594655505|ref|XP_007176141.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Balaenoptera acutorostrata scammoni]
MAFVWDLRGVTVPGPSTRVKSRLRFSKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTAEVIPEELKSRLE
VISEEGGYPSLLTAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISN
TFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELS
GNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAA
IFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDM
SKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGME
ISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQ
FELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVGEEEEESQPEACAIGAHSPDT
>gi|529444647|ref|XP_005242035.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Falco peregrinus]
MAQQTSPGTLAVPEVDNKHCQNPWLNEDLVKTLRENLLQHEKSRTSRKSSSASPRLCPVISPRNSPRLLRRMLLNSNIPK
QRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
VTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEGYQNLAMQTQEKILWCFQKVITVQCYRRTSL
QSNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPR
FGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMYTIFQERDLLKIFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPAPDGQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VGEEVEEEENHTEPCVVEDHSPHT
>gi|498969936|ref|XP_004547277.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Maylandia zebra] >gi|542225987|ref|XP_005452172.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X9 [Oreochromis niloticus]
MSIILKPRSRSTSSLKNTEGICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLD
QLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVK
KLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYL
MTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDS
SVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDR
IQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWAD
LVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEE
ENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|594655507|ref|XP_007176142.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Balaenoptera acutorostrata scammoni]
MSIIMKPRSRSTSSLRTSEGVCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTAEVIPEELKSRLEVISEEGGY
PSLLTAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHE
VEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVI
MHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHD
VDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLA
DLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKH
NASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEED
GESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVGEEEEESQPEACAIGAHSPDT
>gi|543263217|ref|XP_005422033.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Geospiza fortis]
MAQQTSPDNFPVPEVDNAHSQNPWLNEDLVKTLRENLLQHEKSRTTRKSSPASPRLCPVISPRNSPRLLRRMFLNSNIPK
QRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLI
VTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITEEPTGKLKGVSLQKTATCLEDLLTLQTWRSISA
VASTFFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDE
QVGEEVEEDENQTAEPCVVEEHSPDT
>gi|594655509|ref|XP_007176143.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Balaenoptera acutorostrata scammoni]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTAEVIPEELKSRLEVISEEGGYPSLLTA
EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSP
TQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQ
ERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTE
KDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVGEEEEESQPEACAIGAHSPDT
>gi|554849356|ref|XP_005934969.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Haplochromis burtoni]
MSEALLESSGEAGSFPLSSPQPIKLKPQSPSGSPYESPRMSPGDSPRNSPRHSPLLFRKLLMNRNIALQRRFTLAYTPSF
DVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASL
RTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLN
RELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENL
LAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQS
THVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQN
LSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQ
WTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIP
RSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLS
PDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|512809754|ref|XP_004910403.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Xenopus (Silurana) tropicalis]
MSLPSSCEYLTLEKVARFRSAYIHGSPYAINKPIDIKQQRKRFDVDNGTTSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYELSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPE
EAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPA
QKEKEKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKSENEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQE
REMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVS
NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGKQGQTEKFQFELTLEEDGESDTEK
DSGSQVEEDTSCSDSKTLCTQDSESTEIPLDDQVDEEESQLEPNSIEQAHSPDT
>gi|658867465|ref|XP_008416605.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Poecilia reticulata]
MSIILKPRSRSTSSLKNTEGICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDMIVTPFAQVLASLRTVRNNFGTLTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLD
QLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVK
KLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYL
MTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDS
SVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDR
IQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWAD
LVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEE
ENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAANEEVAEDEEEEKSPDT
>gi|512814530|ref|XP_004911041.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Xenopus (Silurana) tropicalis]
MSLPTNCGFLALTDCSGRRFCNGNIYGSPCAVNRPIDIVQRRRRFDVENGLSSGRSPLESQASPGSGLVLQGNFPHSQRR
ESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVSNKRSSGSNQPSACKPNL
SEDAVQKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDKQHEVEIPT
PVSKEKDKKKRPMSQISGVKKLTHSSSFSNCSIPRFGVKTEQEVPLAKEVENINKWGLDIFKVAEYSGNRPLTVIMYSIF
QERDLLKTFHIPVDTFITYMMTLEDHYHSDVAYHNNIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPG
VSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTM
VETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIIVEFFHQGDREREKGMEISPMCDKHNASVE
KSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPQSPSPPPEEQDPDRGNAAGDKFQFELTLEEEGESD
TEQEDTESPIDEENSDSKIHATDDSAQASDEAEQSSPVDLCMTVSSKLDHLEIPPKSTLTKQKKILNFDNLKLAGERTIQ
QKEVSSSHATPANSARQEGTGQAEICLDQEGNITYLPLGT
>gi|617386811|ref|XP_007548211.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Poecilia formosa]
MSIILKPRSRSTSSLKNTEGICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLD
QLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVK
KLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNLFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYL
MTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDS
SVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDR
IQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWAD
LVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEE
EENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAADEEVAEDEKEGKSPDT
>gi|532067622|ref|XP_005319657.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Ictidomys tridecemlineatus]
MSIIMKPRSRSTSSLRTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLKELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIQDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKXXXXXVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEESQPEAPVIDDCSPDT
>gi|548356295|ref|XP_005730275.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Pundamilia nyererei]
MSEALLESSGEAGSFPLSSPQPIKLKPQSPSGSPYESPRMSPGDSPRNSPRHSPLLFRKLLMNRNIALQRRFTLAYTPSF
DVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASL
RTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLN
RELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENL
LAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQS
THVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQN
LSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQ
WTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIP
RSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLS
PDPRSSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|532067624|ref|XP_005319658.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Ictidomys tridecemlineatus]
MAFVWDPLGATVPGPSPRAKSRFHFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLK
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVD
TLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIQDVDHPGVSNQFLINTNSELA
LMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKXXXXXVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPL
WETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSC
SDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEAPVIDDCSPDT
>gi|410924650|ref|XP_003975794.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Takifugu rubripes]
MSELCTESSEESELEDIPQDQRLPRLIKLMPRSKAGSPGGSPKNSPRGSPRNSPLLFRKLMMNRSINLQRRRFTLAHTPS
FDVENGLSVGRSPLDPQASPGSGLVIQANFPHSQRRESFLYRSDSDFDLSPKGPSRNSSTASDLHTEDMIVTPFAQVLAS
LRTVRGNFAIITNQQDRPVSKLFCINTYEEEPHQQLAIETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELSQLS
ETSRSGNQVSEFISSTFLEKQHDMDIMSTPTKEKDKKKRPMSQISGVKKATHSPSLAPSTIPRFGVNASQEGLLAKEMED
VNRWGIDIFKIAEYSGRRPLTVTMYTIFQERELLKSFKIPTDTFLTFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEDNCDIFQNLSKKQRQ
SLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMV
EFFTQGDRERDKGMEISPMCDKQNASIEKNQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPGP
EQQEVGGHAGEASALSRGSGSTDKFQFKLTLEEEGESDTESTPEEEESYSAGPGSKLSRTDPGSRFDAVSTMTRLLTKKL
TTDSTRTFSVDSEKDMSEDKEAEQEDAPGVSRFRIGT
>gi|499028276|ref|XP_004564865.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Maylandia zebra]
MSEALLESSGEAGSFPLSSPQPIKLKPQSPSGSPYESPRMSPGDSPQNSPRHSPLLFRKLLMNRNIALQRRFTLAYTPSF
DVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASL
RTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLN
RELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENL
LAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQS
THVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQN
LSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQ
WTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIP
RSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLS
PDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|114600121|ref|XP_001138439.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 6 [Pan troglodytes]
MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPSGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
AGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRIYKKELTHLS
EMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEAC
VIDDRSPDT
>gi|657571970|ref|XP_008289578.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Stegastes partitus]
MSIILKPRSRSTSSLKNTEGICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLD
QLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVK
KLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYL
MTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDS
SVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDR
IQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWAD
LVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEE
EENSCTDSKTLCTQDSESTEIPLDEQVGEDEDEEEEEEVVVEGGAPCWSPCFVVEEVVAEEEEEEEEEEKEKSPDT
>gi|542225983|ref|XP_005452170.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X7 [Oreochromis niloticus]
MKPGQCPGAPTDRSMMHLSHFPFRRHSWICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETL
EELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKP
MSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIP
LDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEE
EEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|498969932|ref|XP_004547276.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Maylandia zebra]
MKPGQCPGAPTDRSMMHLGHFPFRRHSWICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETL
EELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKP
MSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIP
LDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEE
EEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|594655493|ref|XP_007176135.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Balaenoptera acutorostrata scammoni]
MKRNTCDLLSRSKSASEETLHSTNEEEDPLRGMEPYLVRRLSCRSVQLPPLAFRQLEQADLKSELENTQRPTSLPLKILP
LIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTAEVIPEELKSRLEVISEEGGYPSLLTAEEAYQ
KLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEK
EKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLL
KTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFL
INTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKV
TSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGF
IDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGS
QVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVGEEEEESQPEACAIGAHSPDT
>gi|617386807|ref|XP_007548210.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Poecilia formosa]
MKPGQSPGVPCDRSMMHLSQFPVRRHSWICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETL
EELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKP
MSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNLFKISEFSGNRPLTVMMYTIFQERDLLKTFKIP
LDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEE
EEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAADEEVAEDEKEGKSPDT
>gi|554547080|ref|XP_005868095.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3 [Myotis brandtii]
MTAKNSSKELTASEPEVCIKTFKEQMHLELELPRPPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTLC
FDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLA
SLRSVRNNFTLLTNLQCPGHTEEGSGSGDSAMDSLPPLQPNYMSVCLFAEEPYQKLAMETLEELDWCLDQLETIQTYRSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNN
TSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSD
VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAV
GFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHC
ADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDIL
DTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPESRDSLGET
DVDNAAEDKSPVDT
>gi|542225989|ref|XP_005452173.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X10 [Oreochromis niloticus]
MVKIQNIFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTP
FAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPR
FGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHN
NIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDSKTLCTQDS
ESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|658867463|ref|XP_008416604.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Poecilia reticulata]
MKPGQSPGVPCDRSMMHLSQFPVRRHSWICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGTLTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETL
EELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKP
MSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIP
LDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEE
EEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAANEEVAEDEEEEKSPDT
>gi|594655501|ref|XP_007176139.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Balaenoptera acutorostrata scammoni]
MLPEKPVQRSESGREGNLAGGQHVVSFHPRTTLGRSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSD
SDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTAEVIPEE
LKSRLEVISEEGGYPSLLTAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQV
SEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVF
RIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTD
LEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDI
VLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRE
RERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQG
QTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVGEEEEESQPEACAIGAHSPD
T
>gi|551498769|ref|XP_005800936.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Xiphophorus maculatus]
MAGGSWQAVRGGEERLRLRQGTIKGGEGPMRREAEGGEKQQEADRLSGSRCFQHSGSWTAAHQHATRTALPHLKRVFYFH
SRGSFVGKMECATLSREGAGLAKPPKHLWRQPRTHIRIKQRFNSDTERYLCRNRTLEKLRPGLKKPRMSWPSSLRRQSGA
SVTSSASTLASQGCTVLAFVCRGAAAAALCLCCAALLKEADWIAESPVEKGDEDPEAGSVQGPSDMSEAVLESSGAQPVK
LQSASSSPCGSPRMSPCDSPRDSPRHSPLLFRKLLVNRSIALQRRFTLAHTCFDVENGLSVGRSPLDSQTSPGSGLVLQG
NFPHSQRRESFLYRSDSDFDLSPKNMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNVAALTHLQDRVVNKRPSSASQ
PPLCKPCLSEEPYQKLTMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEK
QHDLEILSPPAKEKEKKKRPMSQISGVKKATQSPSLAPACIPRFGVNTPHESMLAKEIEDLNRWGMDIFKLAEYSGNRPL
TVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIMAALFASA
IHDVDHPGVTNQFLINTSSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLGKKQKDSLRKMVIDMVLATDMSKHMN
FLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMC
DKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPTSPDEPHAEVGPAAGTPGSGGA
FPSSGGDKFQFELTLEEEEEDEEEAGSDLESPLEEESQTSGDRRHNSSSPSLSPDPRSGGGSNRYRPPSPHPSRTLSLAS
MSVRSPHPHRTLGSPGPEASDRNRELSQEGDGVACLPMGT
>gi|551486739|ref|XP_005794949.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Xiphophorus maculatus]
MEPFMVRRLSCRTVQLPPLAFRQAEQYYFDRKPDPDTVTVPPRPTTLPLRAPPLIAITSADTTSFDVDNGTSSGRSPLDP
MASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQ
DRASNKRSPICNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGN
QVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGL
NVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAV
FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMV
IDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQG
DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDG
TRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGDAEE
EGETPCSEPCVADEEVAEDEEEKKSPDT
>gi|594655503|ref|XP_007176140.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Balaenoptera acutorostrata scammoni]
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTAEVIPEELKSR
LEVISEEGGYPSLLTAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYI
SNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAE
LSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIL
AAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLAT
DMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERG
MEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEK
FQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAVGEEEEESQPEACAIGAHSPDT
>gi|551486747|ref|XP_005794953.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Xiphophorus maculatus]
MDRTYAVDTGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDL
SPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPICNPPPITKTTFTEEAYQKLATET
LEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNK
PMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKI
PLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNS
ELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGV
LLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIV
HPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEE
EEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGDAEEEGETPCSEPCVADEEVAEDEEEKKSPDT
>gi|551486741|ref|XP_005794950.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Xiphophorus maculatus]
MSLPVNSDYLSLEKIARYRHACSNGSPYATNKPIDIKPRSRRGFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRE
SFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPICNPPPITKTTF
TEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPS
PQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTI
FQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHP
GVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASV
EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGES
DTEKDSGSQPEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGDAEEEGETPCSEPCVADEEVAEDEE
EKKSPDT
>gi|542225985|ref|XP_005452171.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X8 [Oreochromis niloticus]
MLFHSSSPWVMAEHVIPRAAEVKCSSIFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEEL
DWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQ
ISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDT
FITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELAL
MYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLD
NYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW
ETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEE
EEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|617386798|ref|XP_007548208.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Poecilia formosa]
MEPFMVRRLSCRTVQLPPLAFRQAEQYYCDRKPEPDTVTVPPRPTTLPLRAPPLIAITSADTTSFDVDNGTSSGRSPLDP
MASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQ
DRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGN
QVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGL
NLFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAV
FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMV
IDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQG
DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDG
TRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEG
NAEEEGETPCSEPCAADEEVAEDEKEGKSPDT
>gi|498969920|ref|XP_004547273.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Maylandia zebra] >gi|542225973|ref|XP_003446184.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Oreochromis niloticus]
MQKDDRSGDDSQRDSVSDDSSDSPEPGPVTCMEPFMVRRLSCRTVQLPPLAFRQAEQYYCDRKPEPDTVTVPPRPTTLPL
RTPPLIAITAADTSSFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIH
GDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSS
LTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHY
HADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHH
LAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNM
VHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQ
DILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDS
KTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|542225981|ref|XP_005452169.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Oreochromis niloticus]
MSLPVNYLSLERIARYRHACSTGSPCATNKPIDIKPRGRRGFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESF
LYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTE
EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQ
TQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQ
ERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDT
EKDSGSQPEEEEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEE
EEEEKAKSPDT
>gi|533141345|ref|XP_005385353.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3 [Chinchilla lanigera]
MTAKNSSKELTASESDVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTLC
FDVENGPSPGRSPLDPQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLA
SLRSVRNNFTLLTNLHGAARRGPVLRPFPSRPLPPQEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVASSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLEERSRDCPGLVEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDLLGETDVDPATEDKSPVD
T
>gi|498969928|ref|XP_004547275.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Maylandia zebra]
MSLPVNYLSLEKIARYRHACSTGSPCATNKPIDIKPRGRRGFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESF
LYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTE
EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQ
TQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQ
ERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDT
EKDSGSQPEEEEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEE
EEEEKAKSPDT
>gi|657571968|ref|XP_008289577.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Stegastes partitus]
MKPGQCPGVPSDRSMMHLSHFPFRRHSWICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLS
PKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETL
EELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKP
MSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIP
LDTFITYLMTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVH
PLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEE
EEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDEDEEEEEEVVVEGGAPCWSPCFVVEEVVAEEEEEEEEEEKEK
SPDT
>gi|625190602|ref|XP_007636675.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Cricetulus griseus]
METSGVGRAGVPRAPNHLWRQPRRPIRIQRRFHSDPEPSERPALVKSRRSWPSSFHRRFDLENGFASSRGPLDPQSGRVL
QPPGQHGLRRESFLYRSESDHEPSPKAVSRNSSVASDVHGEDMIVTPFAQVLASLRTVRSNVAALAHGPGRYGDGNGTGS
SLGVLPXPAWPSEDAGLQLARETLEELDWCLEQLETLQTRRSVDEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTF
LDQQAEVELPRLPREDTRPMSQISALRGPRPTGLPTAAVPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAQLSGNRPLTA
IMFSVLQERDLLKTFRIPADTLLAYLLMLEGHYHADVAYHNSVHAADVAQSAHVLLGTPALEAVFTDLEVLAAIFACAIH
DVDHPGVSNQFLINTNSELALMYNDVSVLENHHLAVGFKLLQAENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLL
ADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLQLYRQWTNRIMAEFFQQGDRERESGLDISPMCDK
HTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNREWYQSRIPCSPSHTMGQHCSGPDKFQFELTLEEAEEE
ENEGQSPLLPGACGGADKQGSPVALERVERHRFLAGVAEHPGDKLFWSFCGASAAGQLAPTRRSRSPTNEAFLLPRSSAL
RGSPALPPEPALASGTPWLPARPLPLTSRARLHRSPAPGFAGRQRGLQGPEPPPPPAARSRPWGPVTSAVARVSAVGVAS
ARSGQGERARA
>gi|532055857|ref|XP_005370641.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Microtus ochrogaster]
MRQSGMTXSFLLGERVPEPVDSGTAPASALGGGMIRRPFSGTLLLPPLSSRLASSGEAESDAHVVFTIGTRGIERSQGPT
QSSFDLENGLASCRGPLDPQSGRVLQPPGQQGQRRESFLYRSDSDHEPSSKAVSRNSSVASDLHGEDMIVTPFAQVLASL
RTVRSNVATLAHNPGSATRQPLLGTPPCSSQLAAPTEDAGLQLAQETLEEMDWCLEQLETLQTRRSVGEMASNKFKRMLN
RELTHLSETSRSGNQVSEYISQTFLDQPAEVELPRLPTEDTRPMSRISALRGPRPASLPTTAVPRFGVQTDQEAQLAKEL
EDTNKWGLDVFKVAELSGNRPLTAVMFSVFQERDLLKTFQIPADTLLTFLLTLEAHYHADVAYHNSVHAADVAQSVHVLL
GTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDMSVLENHHLAVGFKLLQAENCDIFRNLSAKQ
RLSLRRMVIDMVLATDMSKHMSLLAELKTMVEMKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRI
MAEFFQQGDRERELGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNRQWYQSRIPCSPTH
AVGQEHCGPDRFQFELTLEEAEEEEEEGLAQH
>gi|512809747|ref|XP_004910402.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Xenopus (Silurana) tropicalis]
MDTEGSKLSALLNSSSNCSNGSSDSSSSTGNLKAPKHLWRQEQHHIYPVHQPQSPALSPSQVSPGLQPQIYPDLQPQPSS
QINPALQPQSPPQIQAQPHPLLPFQLQPQLHSQAQPAPHCPPVSSRTRYSNSRVRHRGFSDTERYLHCQAMDRSSYAVDT
GHRPGLKKSRMSWPSSFQGFRRFDVDNGTTSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYELSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKLAGETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKKL
MHSSSLTNSNIPRFGVKSENEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDDQVDEEESQLEPNSIEQAHSPDT
>gi|617386802|ref|XP_007548209.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Poecilia formosa]
MSLPVNSDYLSLEKIARYRHACSNGSPYATNKPIDIKPRARRGFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRE
SFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTF
TEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPS
PQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNLFKISEFSGNRPLTVMMYTI
FQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHP
GVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASV
EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGES
DTEKDSGSQPEEEEEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAADEEVA
EDEKEGKSPDT
>gi|542225979|ref|XP_005452168.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Oreochromis niloticus]
MDPACGKVGTAPLVAGGGTGLSAKAPKHLWRQQNQAALSPLHHALVVRKNDRVRQRGFSDTERYLNPRNMDRTYAVDTGH
RPGLKKSRMSWPCSSCRCFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIAS
DIHGDDMIVTPFAQVLASLRTVRNNFGALTNLHPLKRALTDPLPSCLAPAEEAYQKLATETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTN
SNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHAD
VAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAV
GFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHC
ADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDIL
DTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDSKTL
CTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|658867459|ref|XP_008416602.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Poecilia reticulata]
MQKDDRSGDDSQRESASDESSDSPEPGPVTCMEPFMVRRLSCRTVQLPPLAFRQAEQYYCDRKPEPDTVTVPPRPTTLPL
RAPPLIAITSADTTSFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIH
GDDMIVTPFAQVLASLRTVRNNFGTLTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSS
LTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHY
HADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHH
LAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNM
VHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQ
DILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDS
KTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAANEEVAEDEEEEKSPDT
>gi|617386790|ref|XP_007548205.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Poecilia formosa]
MEPACGTVGTAPLVAAGGAGVSAKAPKHLWRQQNQASLSPLRHALAVRKNDRVRQRGFSDTERYLSARNMDRTYAVDTGH
RPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSI
ASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQL
ETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKL
QHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNLFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMT
LEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEEE
NSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAADEEVAEDEKEGKSPDT
>gi|658867457|ref|XP_008416601.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Poecilia reticulata]
MEPACGTVGTAPLVAAGGAGVSAKAPKHLWRQQNQASLSPLRHALAVRKNDRVRQRGFSDTERYLSARNMDRTYAVDTGH
RPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSI
ASDIHGDDMIVTPFAQVLASLRTVRNNFGTLTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQL
ETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKL
QHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMT
LEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEEN
SCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAANEEVAEDEEEEKSPDT
>gi|542231032|ref|XP_005454079.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Oreochromis niloticus]
MSEALLESSGEAGSFPLSSPQPIKLKPQSPSGSPYGSPRMSPGDSPRNSPRHSPLLFRKLLMNRNIALQRRFTLAYTPSF
DVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASL
RTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLN
RELTQLSETSRSGNQVSEFIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKATQSPGLAPASIPRFGVNTPHENL
LAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFEIPVDTFITFMMTLEDHYHADVAYHNNIHAADVVQS
THVLLSTPALEAVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQN
LSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQ
WTDRIMKEHFTQGDRERDRGMEISPMCDKHNASIEKTQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIP
RSPSPSTPEEHHAEVGPAAVGAGAPIPSGGGGGDKFQFELTLEEEEEEDEEADSDLESPIEDQSQSAGERHRDSSPPSLA
PDPRSSSGSRYRPPSPHPSRTLNLAAMSVRSPNPHRALASPGREGVDRDRELSQEGDGVACLRLGT
>gi|542225971|ref|XP_005452165.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Oreochromis niloticus]
MDPACGKVGTAPLVAGGGTGLSAKAPKHLWRQQNQAALSPLHHALVVRKNDRVRQRGFSDTERYLNPRNMDRTYAVDTGH
RPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSI
ASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQL
ETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKL
QHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMT
LEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEEN
SCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|512809743|ref|XP_004910401.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Xenopus (Silurana) tropicalis]
MDTEGSKLSALLNSSSNCSNGSSDSSSSTGNLKAPKHLWRQEQQQRWQCPALHHHQSFVQHQEPPAPLHPALPDTPLLLS
QQNIYPLLHPLPLAQINPALQPQIYSVLPSQPAPQILPALQAHIYPVHQPQSPALSPSQVSPGLQPQIYPDLQPQPSSQI
NPALQPQSPPQIQAQPHPLLPFQLQPQLHSQAQPAPHCPPVSSRTRYSNSRVRHRGFSDTERYLHCQAMDRSSYAVDTGH
RPGLKKSRMSWPSSFQGFRRFDVDNGTTSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYELSPKSMSRNSSI
ASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSINKATIPEEAYQKLAGETLEELDWCLDQLE
TLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKKLMH
SSSLTNSNIPRFGVKSENEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLE
DHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLE
NHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVL
QNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
DAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQD
SESTEIPLDDQVDEEESQLEPNSIEQAHSPDT
>gi|432873739|ref|XP_004072366.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Oryzias latipes]
MSLPVNSDYQSLERIARYRHACSNGSPYATNKPIDIKPRVRRGFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRE
SFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTF
TEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPT
PQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKITEFSGNRPLTVMMHTI
FQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHP
GVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASV
EKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGSRPPGGDKFQFELTLEEDGES
DTEKDSGSQPEEEEEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDEDDEEEEHEEVLEGETPCSKACVVEEEVT
EEVEEEQKSSES
>gi|657815919|ref|XP_008335089.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Cynoglossus semilaevis]
MSLPVNSEYLSLERIARYRYACSNGSPCAMNNPIDIKPRGKRGFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRE
SFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRVFNKRSPMCNPAPITKTAF
TEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVELPS
PHMQKEKEKKNKPMSQISGVKKLQHSSSLSNSNIPRFGVKTETENELAKELEHVNKWGLNVFKISEFSGNQPLTVMMYTI
FQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHP
GVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYCQWTDRIMEEFYSQGDRERERGMEISPMCDKHNASV
EKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGES
DTEKDSGSQPEEEDEEEEDNSCTDSKTLCTQDSESTEIPLDEQVVEEEEEVAKNQEEVPCLQPCVLEDVAEVEDNKKSSD
T
>gi|657571966|ref|XP_008289576.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Stegastes partitus]
MQKNDRSGDDSQRDSVSDDSSDSPEPGPVTCMEPFMVRRLSCRTVQLPPLAFRQAEQYYCDRKPESDTVTVPPRPTTLPL
RTPPLIAITSADASSFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIH
GDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQT
RHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSS
LTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHY
HGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHH
LAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNM
VHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQ
DILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEEENSCTD
SKTLCTQDSESTEIPLDEQVGEDEDEEEEEEVVVEGGAPCWSPCFVVEEVVAEEEEEEEEEEKEKSPDT
>gi|532067618|ref|XP_005319655.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Ictidomys tridecemlineatus]
MEAEGSSVPARAGSGEGSDGTGGATLKAPKHLWRQEQHHQYPLRQPQFRVLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
LPPPPPPPGAARGRYASSGASSRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTS
AGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLKELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
EMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELED
VNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIQDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQ
SLRKXXXXXVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIME
EFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEAPV
IDDCSPDT
>gi|658844799|ref|XP_008404824.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X7 [Poecilia reticulata]
MSEAVLESSGAQSVKLQSASSSPCGSPRMSPCDSPRHSPLLFRKLLVNRSIALQRRFTLAHTPSFDVENGLSVGRSPLDS
QTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNVAALTHLQD
RVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQ
VSEFIASTFLEKQHDLEILSPPSKEKEKKKRPMSQISGVKKATQSPSLAPACIPRFGVNTPHESMLAKEIEDLNRWGMDI
FKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLSKKQKDSLRKMVID
MVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDR
ERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPTSPDEPHAEV
GPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEDEEEAESDLESPLEEESLTSGDRRHDSSSPSLSPDPRGGGSSRYRPPS
PHPSRTLSLASMSVRSPHPHRTLDSPGPEASDRNRELSQEGDGVACLRMGT
>gi|507710567|ref|XP_004646948.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Octodon degus]
MPPPVWSAGTQPRPRRDAVTGEDFGEPLGNPFGIAGDSLAMAAPEGADGAEVSSRLGQARGRQGSPRPPKHLWRQPRRPI
RIQQRRHSDPDNPLGCCDPARSTRPGLGTTQRSWPTSFRQRFDLDNGPSCGRAAQAPGSHSQRRESFLYRSDSDYELSPK
AMSRNSSTGSDLHGEDLIVTPFAQVLASLRTVRSNMASLTQGQGSRAVGSASVSSPPVSSQLPPAAEDAAQMLALETLAE
LDWCLDQLEALHTRHSVGDMASTKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQHADVELPPRPLSEIPALGGLTRP
GLSSAAVPRFGVETDQEGQLAKELEDTSKWGLDVFRVAELSGNRPLTAILFSIFQERDLLKTFQIPADTLATYLLTLEAH
YHVDVAYHNSLHAADVAQSAHVLLAMPALQAVFTDLEVLAALFASAIHDVDHPGVSNQFLINTKSELALMYNDISVLENH
HLAVGFKLLQGENCDIFQNLSAKQWLSLRRMAIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDTYADRIQVLQN
LVHCADLSNPTKPLPLYRRWTDRIMAEFFRQGDRERQSGLDVSPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDA
QDLLDTLEDNRSWYHSRVPRSPLDSVGSERGTPSRFQFELTLEETEEEAAVAPDAPST
>gi|657815912|ref|XP_008335086.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Cynoglossus semilaevis]
MDPVCGKVGTASLVAVGGTGVSAKAPKHLWRQQNQTALSPLHHALVARRNDRVRQRGFSDTERYLKPRNMDRTYAVDTGH
RPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSI
ASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRVFNKRSPMCNPAPITKTAFTEEAYQKLATETLEELDWCLDQL
ETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVELPSPHMQKEKEKKNKPMSQISGVKKL
QHSSSLSNSNIPRFGVKTETENELAKELEHVNKWGLNVFKISEFSGNQPLTVMMYTIFQERDLLKTFKIPLDTFITYLMT
LEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYCQWTDRIMEEFYSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEDEEEEDNSCT
DSKTLCTQDSESTEIPLDEQVVEEEEEVAKNQEEVPCLQPCVLEDVAEVEDNKKSSDT
>gi|554849350|ref|XP_005934966.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Haplochromis burtoni]
MSEALLESSGEAGSFPLSSPQPIKLKPQSPSGSPYESPRMSPGDSPRNSPRHSPLLFRKLLMNRNIALQRRFTLAYTPSF
DVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGE
DMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPA
SIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADI
AYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVG
FKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCA
DLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQS
AAERHRDSSSPSLSPDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLG
T
>gi|551519241|ref|XP_005811116.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Xiphophorus maculatus]
MSDLCSESSEEELAEVDETPWKQAAGRLPIIQLLPRSKTCSAGGSPKVSPKDSPRGSPRNSPLLFRKLLMNRSINLQRRR
FTLAHTPSFDVENGLSVARSPLDAQSSSSSGLVLQANYPHSQRRESFLYRSDSDFDLSPKGPSRNLSSASDLHSEDMIVT
PFAQVLASLRTVRSNFALITGQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKTRHSVSEM
ASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIISPPTKEKDKKKLPMSQISGVKKATHSLVPSTIPRFG
VNASQEEFLAKELEDVDRWGLDIFKVAEYSGKRPLTVTMYTIFQERDLLKTFKIPADHFINFMMTLEDHYRSDVAYHNNI
HAADVVQSTHVLLSTPALEAVFTDLEILAALFASSIHDVDHPGVSNQFLINTNSELALMYNDLSVLENHHLAVGFKLLQE
DNCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPT
KPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNR
EWYQSMIPRSPSPRPHEPGEGPGSMTTEKFQFVLTLEEEGESDTEGSPREEKGSRSLTKHSGAFDSGSIPTRRLNKILTS
DSGRTFSLDSEKDMAEDRETDPAGPSVVPRFRLGT
>gi|525026533|ref|XP_005060712.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Ficedula albicollis]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSPMCSQPSINKATITEEAYQKLASETMEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQV
FRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVEEEENQTAEPCMVEEHSPDT
>gi|548356289|ref|XP_005730272.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Pundamilia nyererei]
MSEALLESSGEAGSFPLSSPQPIKLKPQSPSGSPYESPRMSPGDSPRNSPRHSPLLFRKLLMNRNIALQRRFTLAYTPSF
DVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGE
DMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPA
SIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADI
AYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVG
FKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCA
DLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQS
AAERHRDSSSPSLSPDPRSSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRL
GT
>gi|545490740|ref|XP_005617479.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X16 [Canis lupus familiaris]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHV
FRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEENSQPEACVIEDHSPD
T
>gi|545199150|ref|XP_005604253.1| PREDICTED: phosphodiesterase 4D, cAMP-specific isoform X4 [Equus caballus] >gi|664711487|ref|XP_008512719.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Equus przewalskii]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHV
FRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACAAEDRSPD
T
>gi|528922143|ref|XP_005196192.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Bos taurus] >gi|528922145|ref|XP_005196193.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Bos taurus] >gi|528998083|ref|XP_005221564.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X12 [Bos taurus] >gi|528998085|ref|XP_005221565.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X13 [Bos taurus] >gi|555953892|ref|XP_005889115.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Bos mutus]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHV
FRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVADEESQPEACVIGDPSPDT
>gi|332232108|ref|XP_003265244.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Nomascus leucogenys]
MTAKDSSKELTASEPEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTLC
FDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLA
SLRSVRNNFTILTNLHAVGSEGSGPILQPLQPNYMPVCLFAEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKF
KRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGV
NTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLH
AADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEE
HCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTK
SLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRN
WYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATED
KCPVDT
>gi|640802672|ref|XP_008057671.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Tarsius syrichta]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHV
FRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPETCIIDDRSPD
T
>gi|594082618|ref|XP_006064904.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Bubalus bubalis]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHV
FRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQGEEEAVADDEESQPEACVIGDPSPD
T
>gi|499028272|ref|XP_004564863.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Maylandia zebra]
MSEALLESSGEAGSFPLSSPQPIKLKPQSPSGSPYESPRMSPGDSPQNSPRHSPLLFRKLLMNRNIALQRRFTLAYTPSF
DVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGE
DMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPA
SIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADI
AYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVG
FKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCA
DLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQS
AAERHRDSSSPSLSPDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLG
T
>gi|556740078|ref|XP_005965587.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Pantholops hodgsonii]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHV
FRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEATETPLDEQVEEEAVAGGEGAQPEACVAGEPSPG
T
>gi|543377077|ref|XP_005531745.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Pseudopodoces humilis]
MLPGSRCPSRRHSCIGFDLDNGPPGRGALDPQASPGAGLVLQGTFSHGQRRESFLYRSDSDYDLSPKAMSRNSSIASDLH
GEDMIVTPFAQVLASLRTVRSNLTHLQDRAGIKRGSSSSLPSGSKTSLSEDAHQKLSRETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDKQHEVEIPSALAKDKEKERRKRPMSQISGVRKLKHGSSLAA
AGIPRFGVRTDHEALLAKELEDTNKWGLDVFKVAEYSGNRPLTVIMYSIFQERDLMKTFRIPVNTFITYMLTLEDHYHAD
VAYHNNLHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAV
GFKLLQEENCDIFQNLSRKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHC
ADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEISPMCDKHTASVEKSQVGFIDFIAHPLWETWADLVHPDAQELL
DTLEDNREWYQSMIPRSPSPPPEGPAVSPATTDKFQFELTLEEEEEEEEGESDTELEGAESPLDEDNSGSKTPGTDDSES
ADTKRPSPGPGDRDSPVPCPRDVDNQRALEGTLPKDGGSGCSVPGPEGSQGLCLDTEGNVTFLSLGT
>gi|632949775|ref|XP_007890348.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Callorhinchus milii]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFAHGQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
HGDDLIVTPFAQVLASLRTVRNNFAALTNLQDLASSSKRSPICNQTPITRTNFTEEAYQKLATETLEELDWCLDQLETLQ
TRNSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHECEMPSPSQKDKDKKKRPMSQISGVKKLTHSSS
LTNSSIARFGVKTDQEELLSKELEKVNKWGLNIFKVAEHSGNRPLTVVMYTIFQERDLLKTFKIPVDTLLTYLMTLEDHY
HADVAFHNNIHAADVAQSTHVLLSTPALEAVFTDLEVLTAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHH
LAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNM
VHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDENNASIEKTQVGFIDYIVHPLWETWADLVHPDAQ
DMLDTLEDNREWYQSTIPQSPSPAPDEDEEGRPGQVDKFQFELTLEEDCESDTEKDSGASQGEDDNSCSDSKTLCTQNSE
STEIQLDDQGDEEEDDDDAPIEICAVEEEEEAADT
>gi|395821948|ref|XP_003784291.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B [Otolemur garnettii]
MTAKDSSKELTASASEVCIKTFKEQMHLELELPRLPGNRQTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQAGTSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTVLTNLHGTANKRSPAASQPPVSRVNLQEESYQKLAMDTLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVSTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEVLAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
SNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKALELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQSRDCQGLLEKFQFELTLEEEDSEGPDKEGEGHGYFSSTKTLCVIDPEDGDPLGETDIDAATEDKSPVD
T
>gi|119575381|gb|EAW54986.1| phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila), isoform CRA_e [Homo sapiens]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHV
FRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPD
T
>gi|542231030|ref|XP_005454078.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Oreochromis niloticus]
MSEALLESSGEAGSFPLSSPQPIKLKPQSPSGSPYGSPRMSPGDSPRNSPRHSPLLFRKLLMNRNIALQRRFTLAYTPSF
DVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGE
DMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKATQSPGLAPA
SIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFEIPVDTFITFMMTLEDHYHADV
AYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVG
FKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCA
DLSNPTKPLELYRQWTDRIMKEHFTQGDRERDRGMEISPMCDKHNASIEKTQVGFIDYIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSMIPRSPSPSTPEEHHAEVGPAAVGAGAPIPSGGGGGDKFQFELTLEEEEEEDEEADSDLESPIEDQSQS
AGERHRDSSPPSLAPDPRSSSGSRYRPPSPHPSRTLNLAAMSVRSPNPHRALASPGREGVDRDRELSQEGDGVACLRLGT
>gi|530639742|ref|XP_005306655.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Chrysemys picta bellii] >gi|530639746|ref|XP_005306657.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Chrysemys picta bellii]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPD
RAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHV
FKIAELSGNRPLTVVMNTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVEGEESHPEPCVLEEDHSPDT
>gi|658844795|ref|XP_008404822.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X5 [Poecilia reticulata]
MSEAVLESSGAQSVKLQSASSSPCGSPRMSPCDSPRHSPLLFRKLLVNRSIALQRRFTLAHTPSFDVENGLSVGRSPLDS
QTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLR
TVRSNVAALTHLQDRVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNR
ELTQLSETSRSGNQVSEFIASTFLEKQHDLEILSPPSKEKEKKKRPMSQISGVKKATQSPSLAPACIPRFGVNTPHESML
AKEIEDLNRWGMDIFKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNNIHAADVVQST
HVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNL
SKKQKDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKW
TDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPR
SPSPTSPDEPHAEVGPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEDEEEAESDLESPLEEESLTSGDRRHDSSSPSLSP
DPRGGGSSRYRPPSPHPSRTLSLASMSVRSPHPHRTLDSPGPEASDRNRELSQEGDGVACLRMGT
>gi|432855017|ref|XP_004068031.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Oryzias latipes]
MSPCDSPRSSPRHSPLLFRKLLINRSIALQRRFTLAHTPSFDVENGLSVGRSPLDSQTSPGSGLVLQGNFPHSQRRESFL
YRSDSDFDLSPKAMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNFAVLTNLHLCSRWPPGSTQPPICKPCLAEEPYQ
KLAMETLEELDWCLDQLETLQTRHSVSDMASNKFKRMLNRELTQLSETSRSGNQVSEFIANTFLEKQHDVEILSPPLKEK
EKKKRPMSQISGVKKATQSPSLPPASISRFGVNTPHESLLAKEIEDIDRWGMDIFKIAEYSGNRPLTVIMYSIFQERDLL
KTFKIQADTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFL
INTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFENLSKKQKDSLRKMVIDMVLATDMSKHINFLADMKTMVETKKV
TNLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVELFTQGDREREKGMEISPMCDKQNASIEKTQVGF
IDYVVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPTSPEEHHNEGRPSDGAVGTGGLAHLGGGGDKFQFEL
TLEEEEEEVDSDLESPIEEESQTSRDRHLDSSSPSLSPDPRNSRYRPPSPHPSRTLNQTSMSVRSLNSHRMLASPGREAV
QDREPSQDGDRVTCLHMGT
>gi|597742197|ref|XP_007233211.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X7 [Astyanax mexicanus]
MECAALTREGAGFAKPPKHLWRQPRTHIRIKQRYHSDTERYLCCNRNAENHRPGLKKPRMSWPSSFHKRFDVENGLSAGR
ALDPQVSPSSGLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELHGEDMIVTPFAQVLASLRTVRSNFAALT
HLQDRGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSR
SGNQVSEFIASTFLEKQHDVEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVEDINRW
GLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALE
AVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRK
MVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFT
QGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSPSPTPEEQD
SQGGGSGSLGAGGAGGEKFQFELTLEEEGESDAESPPAAESSRNPTDSLNRAPSPHPSQTLGLAAMSVRSPRHRTLSPDT
ADRDSSRERD
>gi|512809766|ref|XP_004910406.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Xenopus (Silurana) tropicalis] >gi|512809770|ref|XP_004910407.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Xenopus (Silurana) tropicalis]
MTSPGSGLILQANFVHSQRRESFLYRSDSDYELSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSTMCNQPSINKATIPEEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKSENEECLAKELEDVNKWGLNI
FKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFT
DLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVID
IVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDR
ERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGKQ
GQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDDQVDEEESQLEPNSIEQAHSPDT
>gi|573904573|ref|XP_006640008.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Lepisosteus oculatus]
MECTTLSREGAGLAKPPKHLWRQPRTHIRIKQRYHSDTEKYLYCKAMEKHRPGLKKPRMSWPSSFHKRFDVENGLSVGRS
PLDPQASPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASELHGEDMIVTPFAQVLASLRTVRSNFAVLT
HLQDRVANKRSSGSNPPSVSKPGQPEEAYQKLAVETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSR
SGNQVSEFISSTFLDKQHDVEILSPTPKEKEKKKRPMSQISGVKKLTHSSSLATSSIPRFGVNTDQEDPLAKEIEDINRW
GLDIFKIAEYSGNRPLTVMMYTIFQERELLKSFKIPADTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALE
AVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRK
MVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFT
QGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPHSPSPPPEERE
KEGVTAGDKFQFELTLEEEGESDSESPTEDSSGESRTVGSGELSQDSPSREACPGLDFSAKDNARAPTNTPVQSLAQRTL
PGDSSPEVDMSPSRGTSIENNELDQEGNVTCLPLAVATRLYAADASAALLVEDRLPGWRLCFQATSTIALYPPCPA
>gi|658897711|ref|XP_008431690.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X4 [Poecilia reticulata]
MSDLCSESSEEELAEVNETPWKQATGQLPIIQLLPRSKTCSAAGSPKVSPKESPRGSPRNSPLLFRKLLMNRSINLQRRR
FTLAHTPSFDVENGLSVARSPLDAQTSSSSGLVLQANYPHSQRRESFLYRSDSDFDLSPKGPSRNLSSASDLHSEDMIVT
PFAQVLASLRTVRSNFALITGQQDRAASKTRSSGSHPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKTRHSVSEM
ASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIMSPPTKEKDKKKRPMSQISGVKKVTHSLIPSTIPRFG
VNASQEEFLAKELEDVDRWGLDIFKVAEYSGKRPLTVTMYTIFQERDLLKTFKIPVDHFINFMMTLEDHYRSDVAYHNNI
HAADVVQSTHVLLSTPALEAVFTDLEILAALFASSIHDVDHPGVSNQFLINTNSELALMYNDLSVLENHHLAVGFKLLQE
DNCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPT
KPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNR
EWYQSMIPRSPSPRPHDQGGRGSLEEASVLGEVPGSMTTEKFQFALTLEEEGESDMEGSPREEKGSRSLTKHSGVFDSGS
IPTRRLNKILTSDSGRTFSLDSEKDMAEDRETDPEGPSVVPRFRLGT
>gi|156523204|ref|NP_001096016.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4B [Bos taurus] >gi|126010693|gb|AAI33549.1| PDE4B protein [Bos taurus] >gi|296489157|tpg|DAA31270.1| TPA: phosphodiesterase 4B [Bos taurus]
MTAKDSSKELTASESEVCIKTFKEQMHLELELPRLPANRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGTSNKRSPAAGQPSVSRVNLPEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHADVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKDGEGHSYFGSTKTLCVIDPENRDPLGETEVDITTEDKSPID
T
>gi|548460101|ref|XP_005678361.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Capra hircus]
MTAKDSSKELTASESEVCIKTFKEQMHLELELPRLPANRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGTSNKRSPAAGQPSVSRVNLPEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHADVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKDGEGHSYFGNTKTLCVIDPENRDPLGKTEVDITTEDKSPSD
T
>gi|426215684|ref|XP_004002100.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Ovis aries]
MTAKDSSKELTASESEVCIKTFKEQMHLELELPRLPANRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGTSNKRSPAAGQPSVSRVNLPEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHADVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKDGEGHSYFGSTKTLCVIDPENRDPLGKTEVDITTEDKSPSD
T
>gi|348568976|ref|XP_003470274.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX1 [Cavia porcellus]
MEAEGSNVPGQAGSGEGSDGAGGATLKAPKHLWRQEQHPQYPLRQPQFRLLHPHHHLPAPPPPSPQPQPQCPLQPLPPPP
LPPPPPPGAARGRYASSGSTGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGASA
GRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVSTDLKNLRVVCV
NNVPAPQTNIRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMS
RSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNK
WGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPAL
EAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLR
KMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFF
RQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQ
EEGQQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEESQPEVCVIDD
CSPDT
>gi|524940649|ref|XP_005072259.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Mesocricetus auratus]
MTAKNSSKELTASESEVCIKTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFSSTKTLCVIDPESRDSLEDTDIDITTEDKSPID
T
>gi|655848938|ref|XP_008263324.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Oryctolagus cuniculus]
MTAKNSSKELTASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSAGRSPLDPQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGTSNKRSPAASQTPVSRASLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEGNRDCQGLMEKFQFELTLEEEDSEGPEKEAEGHSYFSSTKTLCVIDPENRDLLGETDVSIATEDKSPVD
T
>gi|583989289|ref|XP_006789853.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Neolamprologus brichardi] >gi|583989291|ref|XP_006789854.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Neolamprologus brichardi]
MASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQ
DRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGN
QVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGL
NVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAV
FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMV
IDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQG
DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDS
TRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEG
ETPCSQSFVVEEEVAEEEEEEEEEEKAKSPDT
>gi|532019753|ref|XP_005353530.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Microtus ochrogaster]
MVKASTRSIQDMTAKNSSKELTASEPEVCIKTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQ
RRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDL
IVTPFAQVLASLRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSE
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTS
ISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVA
YHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGF
KLLQEEHCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCAD
LSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDT
LEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFGSTKTLCVIDPESRDSLEETDI
DIATEDKSPIDT
>gi|511931656|ref|XP_004784841.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3 [Mustela putorius furo]
MTAKESSKELTASESEVYIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTVLTNLHGTSSKRSPAAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRML
NRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTEN
EDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADV
AQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDI
FQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLEL
YRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQS
MIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKEGEGHNYFSSTKTLCVIDPDHRDSLGETDGDTGAEDKSPI
DT
>gi|498969940|ref|XP_004547278.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Maylandia zebra] >gi|542225991|ref|XP_005452174.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X11 [Oreochromis niloticus] >gi|542225995|ref|XP_005452176.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X13 [Oreochromis niloticus]
MASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQ
DRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGN
QVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGL
NVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAV
FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMV
IDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQG
DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDS
TRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVE
EGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|504153589|ref|XP_004588797.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Ochotona princeps]
MTAKNSSKELTASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGTSNKRSPATSQPPVSRASLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDERNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDSENRDLLGETDVNIATEDKSPVD
T
>gi|667273093|ref|XP_008571549.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Galeopterus variegatus]
MTAKDSSKELTASESEVCIKTFKEQMHLELELPRIPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFMVLTNLHGTSNKRSPAASQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLIEKFQFELTLEEEDSEGPEKEGEGHNYFSSTKTLCVIDPENKDSLEETDIDTVTEDKSPVD
T
>gi|658867467|ref|XP_008416607.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Poecilia reticulata]
MASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGTLTNLQQ
DRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGN
QVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGL
NVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAV
FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMV
IDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQG
DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDG
TRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGN
AEEEGETPCSEPCAANEEVAEDEEEEKSPDT
>gi|635107540|ref|XP_007976615.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Chlorocebus sabaeus]
MTAKDSSKELTASEPEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAGSQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
MNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATEDKSPVD
T
>gi|532093528|ref|XP_005332444.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Ictidomys tridecemlineatus]
MTAKNSSKELTASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGTSNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDERNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFSSTKTLCVIDPGNRDSLGETDDVDIVTEDKSPI
DT
>gi|82799484|ref|NP_001032417.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 3 [Homo sapiens] >gi|397470777|ref|XP_003806989.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Pan paniscus] >gi|2580522|gb|AAB96381.1| cyclic AMP specific phosphodiesterase [Homo sapiens] >gi|158261035|dbj|BAF82695.1| unnamed protein product [Homo sapiens]
MTAKDSSKELTASEPEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSAGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
MNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATEDKSPVD
T
>gi|62087742|dbj|BAD92318.1| phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) variant [Homo sapiens]
HSLQDMTAKDSSKELTASEPEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTV
AHTCFDVENGPSPGRSPLDPQASSSAGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFA
QVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKF
KRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGV
NTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLH
AADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEE
HCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTK
SLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRN
WYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATED
KSPVDT
>gi|426329917|ref|XP_004025977.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Gorilla gorilla gorilla]
MTAKDSSKELTVSEPEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
MNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATEDKSPVD
T
>gi|149709506|ref|XP_001500356.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Equus caballus]
MTAKDSSKELTASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVHLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPESRDSLGETGVDMATEDKSPVD
T
>gi|664721482|ref|XP_008517793.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Equus przewalskii]
MTAKDSSKELTASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVHLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPESRDSLGETGVDMATEDKSPID
T
>gi|640801657|ref|XP_008057126.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Tarsius syrichta]
MTAKDSSKELTASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTVLTNLHGTSNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHADVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
MNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLEEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHGYFSSTKTLCVIDPESRDSLGETDIDIAAEDTSPVD
T
>gi|585639200|ref|XP_006879821.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like isoform X2 [Elephantulus edwardii]
MTAKDSSKGLIASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTANKRSPAASQPPASRVNLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTSEXLALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDERNRDCQGLMEKFQFELTLEEEDSEGQEKEGEGHNYFSSTKTLCVIDPENRDSLEETEVEIGTEDKSPTD
T
>gi|560966097|ref|XP_006205442.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Vicugna pacos]
MTAKDSSKELAASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTVLTNLHGTSNKRSGVASFAPLQKMSLTEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHPDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLEEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFGSTKTLCVIDPEDRDSLGETDVDIATEDKSPID
T
>gi|332232106|ref|XP_003265243.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Nomascus leucogenys]
MTAKDSSKELTASEPEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
MNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATEDKCPVD
T
>gi|589949158|ref|XP_006987237.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Peromyscus maniculatus bairdii]
MTAKNSSKELTACSEPEVCIKTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTC
FDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLA
SLRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRML
NRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISHFGVNTEN
EDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADV
AQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDI
FQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLEL
YRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQS
MIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFSSTKTLCVIDPESRDSLEETDIDIATEDKSPI
DT
>gi|410033073|ref|XP_003949484.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B [Pan troglodytes]
MTAKDSSKELTASEPEVCIKTFKEQMHLELELPRLPGNRPTSRKISPRSSPRNSPGFFRKLLVNKSIGQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSAGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
MNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATEDKSPVD
T
>gi|403257844|ref|XP_003921502.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Saimiri boliviensis boliviensis]
MTAKDSSKELTASEPEVCIKTFKEQMHLELEIPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
MNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATEDTSPVD
T
>gi|512958522|ref|XP_004841563.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X7 [Heterocephalus glaber]
MTAKNSSKELTASEPDVCIKTFKEQMHLELELPRLLGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLQGASNKRSPATSQPPVSRVNPQEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHADVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDERNRDCQGLIEKFQFELTLEEDDSEGPEKEGAGHSYFGSTKTLCVIDPENRDPLGETDVDTATEDKSPTD
T
>gi|388454885|ref|NP_001252893.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4B [Macaca mulatta] >gi|544405397|ref|XP_005543192.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4 [Macaca fascicularis]
MTAKDSSKELTASEPEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
MNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATEDKSPVD
T
>gi|560929829|ref|XP_006191062.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Camelus ferus]
MTAKDSSKELAASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHSTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHPDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFGSTKTLCVIDPENRDSLGETDVDTATEDKSLID
T
>gi|533141343|ref|XP_005385352.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Chinchilla lanigera]
MTAKNSSKELTASESDVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGASNKRSPAASQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVASSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLEERSRDCPGLVEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDLLGETDVDPATEDKSPVD
T
>gi|296208176|ref|XP_002750970.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Callithrix jacchus]
MTAKDSSKELTASEPEVCIKTFKEQMHLELEIPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
MNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEREGEGHSYFSSTKTLCVIDPENRDSLGETDIDIATEDTSPVD
T
>gi|597742201|ref|XP_007233213.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X9 [Astyanax mexicanus] >gi|597742203|ref|XP_007233214.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X10 [Astyanax mexicanus]
MHKDHRLPRKSSLFNFGSGRRRHSCIGFDVENGLSAGRALDPQVSPSSGLVLQATFPHSQRRESFLYRSDSDFDLSPKAM
SRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLPDDT
YPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDVEILSPPPK
EKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVEDINRWGLDIFKIAEHSGNRPLTVIMYSIFQERD
LLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQ
FLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETK
KVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQV
GFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSPSPTPEEQDSQGGGSGSLGAGGAGGEKFQFELTLEEE
GESDAESPPAAESSRNPTDSLNRAPSPHPSQTLGLAAMSVRSPRHRTLSPDTADRDSSRERD
>gi|472385107|ref|XP_004411919.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 3 [Odobenus rosmarus divergens]
MTAKESSKELTASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPCPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGASNKRSPAAATQPSVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRML
NRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTEN
EDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADV
AQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDI
FQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLEL
YRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQS
MIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKEGEGHNYFSSTKTLCVIDPDHRDLLGETDGDTGAEDKSPI
DT
>gi|55716045|gb|AAH85704.1| Pde4b protein [Rattus norvegicus]
MTAKNSSKELPASESEVCIKTFKEQMRLELELPKLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGAPNKRSPAASQAPVTRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGPNYFSSTKTLCKPCHAANGLALPVGGGNAASTQPRCG
HV
>gi|597742199|ref|XP_007233212.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X8 [Astyanax mexicanus]
MSLPTNCAFLPPADRSFKVRNGSICGSPYAVNRPIDIVQKRRRFDVENGLSAGRALDPQVSPSSGLVLQATFPHSQRRES
FLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPT
GSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIAST
FLEKQHDVEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVEDINRWGLDIFKIAEHSG
NRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAAL
FASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMS
KHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEI
SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSPSPTPEEQDSQGGGSGSLGAG
GAGGEKFQFELTLEEEGESDAESPPAAESSRNPTDSLNRAPSPHPSQTLGLAAMSVRSPRHRTLSPDTADRDSSRERD
>gi|507556027|ref|XP_004661779.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Jaculus jaculus]
MTAKNSSESEVCIKTFKEQMRLELELPRLPGNRPTSPKISPRTSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCFDVENGP
SPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRN
NFTLLTNLQGAPNKRSPATSQAPISRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLSRELTHL
SEMSRSGNQVSEYISNTFLDKQNDVEIPAPTPKDREKKKKQLMTQISGVKKLMHSSSLNNTSISRFGVSTENEDHLAKEL
EDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLL
STPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQSLTKKQ
RQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRI
MEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSP
PLDERNRDCQGLMEKFQFELTLEEEDCEGPEKEGEGHSYFSNTKTLCVIDPESRGSLGKTDINITTEDKSPINT
>gi|301776530|ref|XP_002923684.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like isoform 2 [Ailuropoda melanoleuca]
MTAKESSKELTASESEVCIKTFKEQMHLELELPRLSGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTVLTNLHGASNKRSPAAASQPIVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRML
NRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTEN
EDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADV
AQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDI
FQNLTKRQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLEL
YRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQS
MIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKEGEGHTYFSSTKTLCVIDPDHRDSLGETDGDTGAEDKTPI
DT
>gi|657522313|ref|XP_008276030.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Stegastes partitus]
MSVPTNCGFCYSVERSITVRSGNIWGSPCAVNRPIDIIQKRRRFDVENGLSVGRSPLDPQASPGSGLVLQANFPHSQRRE
SFLYRSDSDFDLSPKGPSRNSSTASDLHTEDMIVTPFAQVLASLRTVRSNFAVITGQQDRPASKTRSSGSNPPSMCKTSL
AEEPHQQLAIETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKQHDMDIMS
PPAKEKDKKKRPMSQISGVKKATHSPSLAPSSIPRFGVSASQEGLLAKELEDTNRWGIDIFKVSEYSGSRPLTVTMYTIF
QERELLKSFKIPVDTFITFMMTLEDHYHSDVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPG
VSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEDNCDIFKNLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTM
VETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIE
KNQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPHSPSPNPEGPEEGAHAGEASALSAVSSAADKFQFE
LTLEEEGESDTESPPEEEEGYSSSSRAPEAGRTDPTRRLPKMLISDSGRTFSLDSEKDMAEDRETDEEGVSAVARFRLGT
>gi|544405395|ref|XP_005543191.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3 [Macaca fascicularis]
MTAKDSSKELTASEPEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQVLQTDHSAFRCPEESYQKLAMETLEELDWCLDQLETIQTYRSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNT
SISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDV
AYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVG
FKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCA
DLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILD
TLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLGETD
IDIATEDKSPVDT
>gi|8901297|gb|AAF19202.2|AF208023_1 cAMP-specific phosphodiesterase [Mus musculus] >gi|8979837|emb|CAB96770.1| phosphodiesterase 4B, cAMP specific [Mus musculus]
MTAKNSPKEFTASESEVCIKTFKEQMRLELELPKLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQAGSSSGLVLHAAFPGHSQRRESFLYDLDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGINTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLEETDIDIATEDKSPID
T
>gi|632949773|ref|XP_007890347.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Callorhinchus milii]
MMHVNNFPFRRHSWICFDVDNGTSSGRSPLDPMTSPGSGLILQANFAHGQRRESFLYRSDSDYDLSPKSMSRNSSIASDI
GSQRPPNERSRCCSTGLNFLINRHQRPGLVSRRSEPVLTLAVGNHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDLASS
SKRSPICNQTPITRTNFTEEAYQKLATETLEELDWCLDQLETLQTRNSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSE
FISSTFLDKQHECEMPSPSQKDKDKKKRPMSQISGVKKLTHSSSLTNSSIARFGVKTDQEELLSKELEKVNKWGLNIFKV
AEHSGNRPLTVVMYTIFQERDLLKTFKIPVDTLLTYLMTLEDHYHADVAFHNNIHAADVAQSTHVLLSTPALEAVFTDLE
VLTAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVL
ATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERE
RGMEISPMCDENNASIEKTQVGFIDYIVHPLWETWADLVHPDAQDMLDTLEDNREWYQSTIPQSPSPAPDEDEEGRPGQV
DKFQFELTLEEDCESDTEKDSGASQGEDDNSCSDSKTLCTQNSESTEIQLDDQGDEEEDDDDAPIEICAVEEEEEAADT
>gi|512901161|ref|XP_004899416.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Heterocephalus glaber]
MTAKNSSKELTASEPDVCIKTFKEQMHLELELPRLLGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLQGASNKRSPATSQPPVSRVNPQEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKNANLTR
CKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFG
VNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHADVAYHNSL
HAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQE
EHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPT
KSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNR
NWYQSMIPQSPSPPLDERNRDCQGLIEKFQFELTLEEDDSEGPEKEGAGHSYFGSTKTLCVIDPENRDPLSETDVDTATE
DKSPTDT
>gi|147903709|ref|NP_001086133.1| phosphodiesterase 4B, cAMP-specific [Xenopus laevis] >gi|49256211|gb|AAH74239.1| MGC83972 protein [Xenopus laevis]
MTAKESSNELATPDSDIYIKTFKEHMHLELELPRLSGKRTTTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTC
FDVENGPTPGRSPLDHQASPGSGLVLHTNFTSHNQRRESFLYRSDSDYDLSPKTMSRNSSAASEQHGDDLIVTPFAQVLA
SLRSVRNNFTVLTNVHGVPNKRSPMTSQPQISRVNHQEDSYQKIAMDTLEELDWCLDQLETIQTYRSVSEMASNKFKRML
NRELTHLSEMSRSGNQVSEYISSTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLKHSSSLNNTSMSRFGVKTDY
EDMLSKELEDLNKWGLNIFKVASYSCNRPLTCIMYAIFQERDLLKTFKIPVDTLITYTMTLEDHYHSDVAYHNSLHAADV
TQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDI
FQNLTKKQRQSLRKMVIDLVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLEL
YRQWTDRIMEEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWGDLVQPDAQDILDTLEDNRNWYQS
MIPQSPSPLLDEHDKDCQGLSEKFHFELTLEEEDSDGHDKDGDCLSFYSSTKTLHIVDQGMEDSPDADTELLTDDTSPLD
T
>gi|602636189|ref|XP_007424952.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3 [Python bivittatus]
MTAKDSSRELAAPETDIYIKTFKEQMHLELELPRVSGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQAGSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSVPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLQGTSNKRSPAANQLPVSKVNIQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVKTEKE
DHLAKELEDLNKWGLNIFNVARYSHSRPLTCIMYAIFQERDLLKTFKISSDTFIAYMMTLEDHYHTDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
HNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLEERNQDCQGLMEKFQFDLTLEEEDSDGPEKESDSIHYYGSTKTLCVIDPGKRDSQQDANIEIVTKDASPID
T
>gi|637374045|ref|XP_008122607.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C, partial [Anolis carolinensis]
MQVNPNFRSQRRFTVAHALCFDIENGFSPGRSPLEPLANPGQGLVLQGPATHGQRRESFLYRSDSDYDLSPKAMSRNSSV
ASEIHGEDLIVTPFAQVLASLQTVRSNFAVLTHVQQERSGNKRASGPPAPKVNLPEDAVQKLAMETLEELDWCLDQLETL
QTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDKQHEVDIPTSVPKEKAKERKRRPMSQISGVKKLLH
SSSLSCTAVPRFGVRTEQEGLLAKELEDVNRWGLDIFRISEYSGHRPLTVIMYSIFQERDLLKSFQIPVDVFITFMMTLE
DHYHPDVAYHNNIHAADVAQSTHVLLSMPALEAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDASVLE
NHHLAVGFKLLQEENCDIFQNLSKKQRQMLRKMVIDMVLATDMSKHMNILADMKTMVETKKVTSSGVLLLDNYSDRIQVL
QNVVHCADLSNPTKPLELYRQWTERIMVEFFYQGDHEREKGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
DAQEILDTLEDNREWYQSMIPQSPPPPQTPYSADTAEKFRFTLEEEEDSDAEETAEEET
>gi|432911923|ref|XP_004078782.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Oryzias latipes]
MSELNSDSSEEERSAVDEEPQNRGPSKWSVIQLLPRFKAASAAGSPQISTKDSPRGSPRNSPLLFRKLLMNRSINLQRRR
FTLAHTPSFDVENGLSAGRGGPIDAQVNPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKGPTRNPSSASDLHSEDMIV
TPFAQVLASLRTVRNNFSTITGQQDRTVKQDPRHTRPPAVRIPAQQRSYQQLAIETLDELDWCLEQLETLKTRHSVSEMA
SNKFKRMLNRELTQLSETSRSGNQVSEFISSTFLEKSHDMDIMSPPSKEKDKRKRPMSQISGVRKPTYSLAPSSIPRFGV
NASQEGLLAKQLEDINRWGIDIFKVAEYSGTRPLTVTMYSIFQERDLLKTFKIPVDIFINFVMTLEDHYHSEVAYHNNIH
AADVVQSMHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDMSVLENHHLAVGFKLLQED
QCDIFQDLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTK
PLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNRE
WYQSMIPHSPSPGPETQEEEGLPEEASATASGSCSTSADKFHFELTLEEEEESDTESSTEDERGYGRTKNSSECGSSAAL
QRNQAPSKDPGRTFSVGLKSDAAEEGAPEVPHFTLGT
>gi|586528875|ref|XP_006919356.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Pteropus alecto]
MTAKDSSKELTASESEVCIKTFKEQMHLELELPRLQGNRSTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGASNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLK
KKRADTSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEREGEGHNYFSSTKTLCVIDPENRDSLEETDVDIATEDKSPVD
T
>gi|542205050|ref|XP_005476145.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Oreochromis niloticus]
MRRNNSKIFNFTERQWDSLDQTSVEPLQDCDIRWAVKRLFSGNLQLPKLSCRPSAQDGPPPVAPSGPATYRIKHSRSYGT
LTSCMSRGLFDVENGLSVGRSPLDPQASPNSGLARPTNFPHSQRRESFLYRSDSDFDLSPKGPSRNSSTASDLEESLKHW
EVNWLSSRHTEDMIVTPFAQVLASLRTVRSNFAVITGQQDRTASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWC
LEQLETLKTRHSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKQHDMDIMSPPTKEKDKKKRPMSQISGV
KKATHSPSLAPSTIPRFGVNASQEGLLAKELEDINRWGIDIFKVSEYSGNRPLTVTMYTIFQERDLLKSFKIPVDTFITF
MMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYND
LSVLENHHLAVGFKLLQEDNCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSD
RIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDREREKGMEISPMCDKHNASVEKNQVGFIDYIVHPLWETWA
DLVHPDAQDILDTLEDNREWYQSMIPHSPSPHPEGQEEEEEEEDTFAGEASAHCRGSGSASADKFQFKLTLEEEGESDTE
SPPEEEEGQSSSRRHEIYRSDSASPASRRLPKMLTSDSGRTFSLDSEKDMAEERETDEGVSGVPRFRIGT
>gi|47216417|emb|CAG01968.1| unnamed protein product [Tetraodon nigroviridis]
MRTPGKLQRAGQTRTRAKPNRDESGRKLTGTDRGSAAGRQRRGGFDVENGLSVGRSPLDPQASPGSALVIQANFPHSQRR
ESFLYRSDSDFDLSPKGPSRNSSTASDLHTEDMIVTPFAQVLASLRTVRSNFAIITNQQDRPVSKTRSSGSNPPSMCKTS
LAEEPHQQLAIETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKQHDMDIM
SPPTKEKDKKKHPMSHISGVKKATHSPSLAPSTIPRFGVNASQEGLLAKEMEDVSRWGIDIFKIAEYSGRRPLTVTMYTI
FQERELLKSFKIPVDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEVNDPNHPVAVFTDLEILAALFAS
AIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEDNCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHM
NLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPM
CDKQNASIEKNQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPGPEQEEAGGRAIEASALSRGS
GSTEKYQFKLTLEEEGESDTESPPEEEDSYSAGTGSELSRTDP
>gi|554819914|ref|XP_005920700.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Haplochromis burtoni]
MRRNNSKIFNFTERQWDSLDQTSSVEPLQDCDIRWAVKRLFSGNLQLPKLSCRSSAQDGPPPVAPLGPATYRIKHSRSYG
TLTSCMSRGLFDVENGLSVGRSPLDPQASPNSGLARPTNFPHSQRRESFLYRSDSDFDLSPKGPSRNSSTASDLEESLKH
WEVNWLSSRHTEDMIVTPFAQVLASLRTVRSNFAVITGQQDRTASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDW
CLEQLETLKTRHSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKQHDMDIMSPPTKEKDKKKRPMSQISG
VKKATHSPSLAPSTIPRFGVNASQEGLLAKELEDINRWGIDIFKVSEYSGNRPLTVTMYTIFQERELLKSFKIPVDTFIT
FTMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYN
DLSVLENHHLAVGFKLLQEDNCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYS
DRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDREREKGMEISPMCDKHNASVEKNQVGFIDYIVHPLWETW
ADLVHPDAQDILDTLEDNREWYQSMIPHSPSPHPEGQEEEEEEEEDAFAGEASAHGRGSGSASADKFQFKLTLEEEGESD
TESPPEEEEGHSSSRRHEIYRSDSASPASRRLPKMLTSDSGRTFSLDSEKDMAEERETDEGVSGVPRFRIGT
>gi|507656076|ref|XP_004634033.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Octodon degus]
MTAKNSSKELTASESDVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGASNKRSPVASQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQLMTQISGVRKLMHSSSLNNTSISRFGVNTENED
HLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQ
STHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQ
NLSKRQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVASSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYR
QWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMI
PQSPSPPLEERGQDCQGLMEKFQFELTLEEEDLEGPEKEGEGHGYFSSTKTLCVIDPENQDARSETDDVDAATEDKSPAD
T
>gi|1705949|sp|P14644.2|PDE4C_RAT RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C; AltName: Full=DPDE1 >gi|436012|gb|AAA56858.1| phosphodiesterase, partial [Rattus norvegicus]
NSSRTSSAASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGSATRQALLGTPPQSSQQAAPAEESGLQLAQETLEEL
DWCLEQLETLQTRRSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQQAEVELPAPPTEDHPWPMAQITGL
RKSCHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFRVLQERDLLKTFQIPADTLLRYL
LTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDS
SVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDR
IQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWAD
LVHPDAQELLDTLEDNREWYQSRVPCSPPHAIGPDRFKFELTLEETEEEEEEDERH
>gi|657812564|ref|XP_008333662.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Cynoglossus semilaevis]
MASPSSGLILQANFVHSQRRKSFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQ
DRASNKISPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGN
QVSEFISSTFLDKQHEVEMTSPQMQKEKEKKNKPMSQISGVKKLQHSSSLSNSNIPRFGVKTETEDELAKELENVNKWGL
NVFKISEFSGNRPLTVIMYTIVQERDLLKTFKIPLDTFITYLMTLEDHYHGDVAYHNNIPAAHVTQSTHVMPSTPALEAV
FTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMV
IDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYTQWTDRIMEEFFSQG
DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYQSTIPQSPSPALDEPEDG
TRPPGGDKFQFELTLEEDCESDTEKDSGSQPEEEDEEEEYKKEDNSCTDSKTLCTQDSESTEIPLNEQVGEEDREEIPCL
QPYVLEEDIAEVEDNEETEKSSDTAVYGQHLTNCSS
>gi|617427329|ref|XP_007560599.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X2 [Poecilia formosa]
MSRFQNRRESLPAPYQVVRRRFSGPLLLPPLWRRHSCQDQHPRETRRPSAINVIPLDRLQEIYSQALASRDELRFDVENG
LSVGRSPLDSQTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRS
NVAALTHLQDRVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQ
LSETSRSGNQVSEFIASTFLEKQHDLEILSPPTKEKEKKKRPMSQISGVKKATQSPSLAPACIPRFGVNTPHENMLAKEI
EDLNRWGMDIFKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNNIHAADVVQSTHVLL
STPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLSKKQ
KDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRI
MVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSP
TSPDEPHAEVGPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEEEEDEEEAESDLESPLEEESLTSGDRRHDSSSPSLSPD
PRSGGSSRYRPPSPHPSRTLSLASMSVRSPHPHRTLGSPEPEASDRNRELSQEGDGVACLRMGT
>gi|548356297|ref|XP_005730276.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Pundamilia nyererei]
MECTTLSREGAGLAKPPKHLWRQPRTHIRIKQRFNSDTERYLCRNRTLEKLRPGLRQPRMSWPSSLKRFDVENGLSVGRS
PLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNFAVLT
HLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSR
SGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRW
GMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALE
VVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRK
MVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFT
QGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEH
QAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSSG
RYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|499028278|ref|XP_004564866.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Maylandia zebra] >gi|554849358|ref|XP_005934970.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Haplochromis burtoni]
MECTTLSREGAGLAKPPKHLWRQPRTHIRIKQRFNSDTERYLCRNRTLEKLRPGLRQPRMSWPSSLKRFDVENGLSVGRS
PLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNFAVLT
HLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSR
SGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRW
GMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALE
VVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRK
MVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFT
QGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEH
QAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSGR
YRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|583983013|ref|XP_006786798.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Neolamprologus brichardi]
MRRNNSKIFNFTERQWDSLDQTSSVEPLQDCDIRWAVKRLFSGNLQLPKLSCRPSAQDGPPPVAPSGPATHRIKHSRSYG
TLTSCMSRGLFDVENGLSVGRSPLDPQASPNSGLARPTNFPHSQRRESFLYRSDSDFDLSPKGPSRNSSTASDLEESLKH
WEVNWLSSRHTEDMIVTPFAQVLASLRTVRSNFAVITGQQDRTASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDW
CLEQLETLKTRHSVSEMASTKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKQHDMDIMSPPTKEKDKKKRPMSQISG
VKKATHSPSLAPSTIPRFGVNASQEGLLAKELEDINRWGIDIFKVSEYSGNRPLTVTMYTIFQERELLKSFKIPVDTFIT
FVMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYN
DLSVLENHHLAVGFKLLQEDNCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYS
DRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDREREKGMEISPMCDKHNASVEKNQVGFIDYIVHPLWETW
GDLVHPDAQDILDTLEDNREWYQSMIPHSPSPHPEGQEEEEEEEDAFAGEASAHGRGSGSASADKFQFKLTLEEEGESDT
ESPPEEEEGHSSSRRHEIYRSDSASPASRRLPKMLTSDSGRTFSLDSEKDMAEERETDEGVSGVPRFRIGT
>gi|507657547|ref|XP_004718212.1| PREDICTED: LOW QUALITY PROTEIN: phosphodiesterase 4C, cAMP-specific [Echinops telfairi]
MQGSPAAASPRSSSRGSPGLCRKLLTNQSLRLQRRFTVAHPLGWLSSGNPPSSGNPPPASQPPPPTEDTGQRLALETLEE
LDWCLDQLETLQTRHSVGEMASNKFKRMLNRELSHLSETSRSGNQVSEYISQTFLEQQAVVELPRVAPEETPQPMSQISG
LRELPHSASLSAATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSKNQPLTAIMFSIFQERDLLKTFRIPADTLVT
YLLMLEGHYQADVAYHNSLHAADVAQSTHVLLATPALEGVFTDMEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYN
DTSVLENHHLAVGFKLLQTKHCDIFQNLSAKQRLSLRRMVIDLVLATDMSKHMNLLADLKTMVETKKVASLGVLLLDNYS
DRIQVLQNLVHCADLSNPTKPLPLYRQWTERVMAEFFQQGDRERELGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETW
ADLVHPDAQDLLDTLEDNREWYQSKIPRSPPAPNSPQRAGLDRFQFGLTLEEAEEEEEEEEEDQVAADGEAPEGPGTELM
PSEASPTPQTSQLDNQRTRGKPFVDXEENMLAEPFGT
>gi|395735836|ref|XP_003776649.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Pongo abelii]
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQADLKSESENIQRPTSLPLKILP
LIAITSAESSGFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDL
IVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLKSGAHPIFSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSS
IPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSFKENGSLTSVLATDMSKHMNLLADLKTMVETNKVTSSGVLLLDNYSDRIQVLQNMVHCA
DLSNPTKPLQLYRQWTXPGXWEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDIL
DTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEI
PLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|658844791|ref|XP_008404820.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X3 [Poecilia reticulata]
MLQRGAERRQEPRSRGTLAGGGGGQLVETEAEGELTGIAEMSLPTNCMYLAPSVQDRCFKVRSGNICGSPCAVNRPIDIV
QKRRRFDVENGLSVGRSPLDSQTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFA
QVLASLRTVRSNVAALTHLQDRVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLETLQTRHSVSEMASNK
FKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDLEILSPPSKEKEKKKRPMSQISGVKKATQSPSLAPACIPRFGVN
TPHESMLAKEIEDLNRWGMDIFKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNNIHA
ADVVQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLENHHLAVGFKLLQEEN
CDIFQNLSKKQKDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
YQSMIPRSPSPTSPDEPHAEVGPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEDEEEAESDLESPLEEESLTSGDRRHDS
SSPSLSPDPRGGGSSRYRPPSPHPSRTLSLASMSVRSPHPHRTLDSPGPEASDRNRELSQEGDGVACLRMGT
>gi|658844797|ref|XP_008404823.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X6 [Poecilia reticulata]
MECATLSREGAGLAKPPKHLWRQPRTHIRIKQRFNSDTERYLCRNRTLEKLRPGLKKPRMSWPSSLRRFDVENGLSVGRS
PLDSQTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNVAALT
HLQDRVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSR
SGNQVSEFIASTFLEKQHDLEILSPPSKEKEKKKRPMSQISGVKKATQSPSLAPACIPRFGVNTPHESMLAKEIEDLNRW
GMDIFKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALE
AVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLSKKQKDSLRK
MVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFT
QGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPTSPDEP
HAEVGPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEDEEEAESDLESPLEEESLTSGDRRHDSSSPSLSPDPRGGGSSRY
RPPSPHPSRTLSLASMSVRSPHPHRTLDSPGPEASDRNRELSQEGDGVACLRMGT
>gi|543715445|ref|XP_005498996.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Columba livia]
MTAKDSSRELATPESEIYIRTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQAGSSAGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGTSNKRSPAMSQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKVSRAAG
RCEAEHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVKTEK
EDHLAKELEDLNKWGLNIFNVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADV
AQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDI
FQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLEL
YRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQS
MIPQSPSPPLEERGRDCQGLMEKFQFELTLEEEDSDGPEKDSESIGYFSNTKTLCVAEPGEEDSQREANIEIVTEDTSPV
DT
>gi|511886444|ref|XP_004763010.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4B [Mustela putorius furo]
MTAKESSKELTASESEVYIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCF
DVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTVLTNLHGTSSKRSPAAASQPPVSRVNPQAAYPGLXIETLRSLQWCLDFFETPYTYRSISEFVTNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENE
DHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVA
QSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELY
RQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSM
IPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKEGEGHNYFSSTKTLCVIDPDHRDSLGETDGDTGAEDKSPID
T
>gi|499028286|ref|XP_004564870.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X8 [Maylandia zebra] >gi|554849364|ref|XP_005934973.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X8 [Haplochromis burtoni]
MKKDDATFFGKWSCKTTGTISFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSS
TASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLA
METLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKK
KRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTF
DIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINT
SSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSL
GVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDF
IVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEE
EEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGR
EGADTDRELSQEGDGVACLRLGT
>gi|548356305|ref|XP_005730280.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X9 [Pundamilia nyererei]
MKKDDATFFGKWSCKTTGTISFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSS
TASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLA
METLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKK
KRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTF
DIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINT
SSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSL
GVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDF
IVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEE
EEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPG
REGADTDRELSQEGDGVACLRLGT
>gi|499028284|ref|XP_004564869.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X7 [Maylandia zebra] >gi|554849362|ref|XP_005934972.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X7 [Haplochromis burtoni]
MNKDLRLTRKGGLTGFGHGRRHSCLGFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTM
SRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEP
YQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPK
EKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERD
LLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQ
FLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETK
KVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQV
SFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFE
LTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAP
VSPGREGADTDRELSQEGDGVACLRLGT
>gi|548356303|ref|XP_005730279.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X8 [Pundamilia nyererei]
MNKDLRLTRKGGLTGFGHGRRHSCLGFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTM
SRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEP
YQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPK
EKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERD
LLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQ
FLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETK
KVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQV
SFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFE
LTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRA
PVSPGREGADTDRELSQEGDGVACLRLGT
>gi|149036063|gb|EDL90729.1| phosphodiesterase 4C, cAMP-specific, isoform CRA_a [Rattus norvegicus]
MRRSGTTLSFLLTERVREPVDSGVAPVSHLGGGVILRRFSGTLLLPPLSSRLGSSGEAESAAPVVFTIGSRGTERSHGSA
QSSFDLENGLPSGRGPLDAQSGSSLGRALQPPVHHGQRRESFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQV
LASLRTVRSNVAALAHGAGSATRQALLGTPPQSSQQAAPAEESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFK
RMLNRELTHLSETSRSGNQVSEYISQTFLDQQAEVELPAPPTEDHPWPMAQITGLRKSCHTSLPTAAIPRFGVQTDQEEQ
LAKELEDTNKWGFDVFKVAELSGNRPLTAVIFSVLQERDLLKTFQIPADTLLRYLLTLEGHYHSNVAYHNSIHAADVVQS
AHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQN
LSTKQKLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQQGDRERESGLDISPMCDKHTASV
EKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNREWYQSRVPCSPPHAIGPDRFKFELTLEETEEEEEEDERH
>gi|554849354|ref|XP_005934968.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Haplochromis burtoni]
MECTTLSREGAGLAKPPKHLWRQPRTHIRIKQRFNSDTERYLCRNRTLEKLRPGLRQPRMSWPSSLKRFDVENGLSVGRS
PLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVL
ASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKR
MLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPH
ENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADV
VQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDI
FQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEL
YRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
MIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSP
SLSPDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|548356301|ref|XP_005730278.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X7 [Pundamilia nyererei]
MQPASAQFVTGELHHLHRLEGSAYTAGGQVGKARRSHFSWLDSFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRE
SFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRP
SSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIAN
TFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYS
GNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAA
LFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDM
SKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGME
ISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGA
GAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSSGRYRPPSPHPSR
TLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|524972764|ref|XP_005086231.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Mesocricetus auratus]
MEETCILRRGGTALAFLLSERVRGPVDSGAGPADPLGGGVTXRRFSGALLLPPLSCRLGSAGEAESGAHLVFTIEKGQRE
ARAQQASFDLENGFADGRGPLDPQCGRVLQPPGQHGLRRESFLYRSDSDHEPSPRAVSRNPSVARDLHGEDMIVTPFAQV
LATLRTVRSNVAALALVPGSPARRQLLESPPCGSPPAGPTEDAGRQLAREKLEELDWCLQXLETLQTRRSVGEMASNKFK
RMLSRELTHLSETGRSGNQVSEYISKTFLLVGRSVSHRPLRTGRGRRSFPDCPLDARLVTQISALRGPGPSSLPTAVVPR
FGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNQPLTVVMFRVLQERDLLKTFRIPADTLLTYLMTLEGHYHADVAYHN
SVHAADVVQSAHVLLGTPALEAVFTDLEVLATVFACAIHDVDHPGVSNQFLINTNSELALMYNDLSVLENHHLAVGFKLL
QAENCDVFRNLSTKQRLSLRRMVIDMVLATDMCKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSN
PTKPLLLYRQWTDPIMAEFFQQGDRERESGLDISPMCDRHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLED
NREWYQRRIPCSPAHAMGPDRFQFELTLEEAEEEDAESSTLDILSSESPGT
>gi|499028282|ref|XP_004564868.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Maylandia zebra]
MQPASAQFVTGELHHLHRLEGSAYTAGGQVGKARRSHFSWLDSFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRE
SFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRP
SSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIAN
TFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYS
GNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAA
LFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDM
SKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGME
ISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGA
GAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSGRYRPPSPHPSRT
LNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|499028274|ref|XP_004564864.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Maylandia zebra]
MSRLEHFRDSIPVGNHVVRRRYSGPLLLPPLWRRHSHQDHSFDTRRTSQGHMLPLARLEELYSLALATHDEHRFDVENGL
SVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTP
FAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMAS
NKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFG
VNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSI
HAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQE
ENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPT
KPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNR
EWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHR
DSSSPSLSPDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|345800390|ref|XP_003434692.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoformX1 [Canis lupus familiaris] >gi|545498547|ref|XP_005620258.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3 [Canis lupus familiaris]
MKKSRSVMAVTADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLAQRQSERARTPEGDGISRPTTLPLM
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGASNKRSPAATSQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSS
LNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHY
HSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILATIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNM
VHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQ
DILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKEGEGHNYFSSTKTLCVIDPEHRDSL
GDTDGDTGAENKTPIDT
>gi|663280845|ref|XP_008498406.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Calypte anna]
MEEKKSIPSHYYNDTTALRKVITCELALTMVSEEALHHDTEDKEPPQGMEPYLVRRLSSRNILLPPLAFRQLEQADRDKT
IDTKAIPRPMTLPLKIPPLIAITSAESSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSP
KSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITVSNSKELISLDWQY
KKKKKISEANSLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISG
VKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLIT
YLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYN
DSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYS
DRIQVLQNMVHCADLSNPTKPLDLYRQWTDRIMEEFFRQGDRERERGMEISPMCDRHNASVEKSQVGFIEYIVHPLWEAW
ADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEVRQGQTEKFQFELTLNEDGESDTEKDSGSQVEEDTSCSDSK
TLCTQDSESTEIPLDEQVGEDVEEEENQTEPCVVEDHSVDT
>gi|554849352|ref|XP_005934967.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Haplochromis burtoni]
MSRLEHFRDSIPVGNHVVRRRFSGPLLLPPLWRRHSHQDHSFDTRRTSQGHMLPLARLEELYSLALATHDEHRFDVENGL
SVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTP
FAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMAS
NKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFG
VNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSI
HAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQE
ENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPT
KPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNR
EWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHR
DSSSPSLSPDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|548356299|ref|XP_005730277.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Pundamilia nyererei]
MSLPTNCVYLTPSVQDRYFKMRNGNICGSPCAVNRPIDIVQKRRRFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQR
RESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNK
RPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYI
ANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAE
YSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEII
AALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLAT
DMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRG
MEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAAL
GAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSSGRYRPPSPHP
SRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|548356293|ref|XP_005730274.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Pundamilia nyererei]
MECTTLSREGAGLAKPPKHLWRQPRTHIRIKQRFNSDTERYLCRNRTLEKLRPGLRQPRMSWPSSLKRFDVENGLSVGRS
PLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVL
ASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKR
MLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPH
ENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADV
VQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDI
FQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEL
YRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
MIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSP
SLSPDPRSSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|499028280|ref|XP_004564867.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Maylandia zebra] >gi|554849360|ref|XP_005934971.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Haplochromis burtoni]
MSLPTNCVYLTPSVQDRYFKMRNGNICGSPCAVNRPIDIVQKRRRFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQR
RESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNK
RPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYI
ANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAE
YSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEII
AALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLAT
DMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRG
MEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAAL
GAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSGRYRPPSPHPS
RTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|617427326|ref|XP_007560598.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X1 [Poecilia formosa]
MSRFQNRRESLPAPYQVVRRRFSGPLLLPPLWRRHSCQDQHPRETRRPSAINVIPLDRLQEIYSQALASRDELRFDVENG
LSVGRSPLDSQTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVT
PFAQVLASLRTVRSNVAALTHLQDRVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDLEILSPPTKEKEKKKRPMSQISGVKKATQSPSLAPACIPRF
GVNTPHENMLAKEIEDLNRWGMDIFKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLSKKQKDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSMIPRSPSPTSPDEPHAEVGPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEEEEDEEEAESDLESPLEEESLTSG
DRRHDSSSPSLSPDPRSGGSSRYRPPSPHPSRTLSLASMSVRSPHPHRTLGSPEPEASDRNRELSQEGDGVACLRMGT
>gi|548356291|ref|XP_005730273.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Pundamilia nyererei]
MSRLEHFRDSIPVGNHVVRRRFSGPLLLPPLWRRHSHQDHSFDTRRTSQGHMLPLARLEELYSLALATHDEHRFDVENGL
SVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTP
FAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMAS
NKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFG
VNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSI
HAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQE
ENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPT
KPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNR
EWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHR
DSSSPSLSPDPRSSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|47217420|emb|CAG00780.1| unnamed protein product [Tetraodon nigroviridis]
MKLEIKCTLSLSFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGED
MIVTPFAQVILASLRTVRGNFVALTHLQDRVGNKRPTGSNQPPMCKPCVTEEPSPKLALETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIANTFLERQHDVEILSAPPKEREKKKRPMSQISGVKKVIQSPGLASV
SIPRFGVSTPQESQLAKELEQINRWGLDIFKISEFSGHRPLTVIMYSVFQERDLLKTFKIPVGTFVTFVMTLEDHYHADV
AYHNNIHAADVVQSTHVLLSTSALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVG
FKLLQEENCDIFQNLGKKQKESLRKMVIDMVLATDMSKHMNYLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNIVHCA
DLSNPTKPLELYRRWTDRIMREFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSMIPRSPSPSSPDDPDSKGGPGGEAVAAGEAVPSGGGDKFQFELTLEEEEEED
>gi|658897706|ref|XP_008431688.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X2 [Poecilia reticulata]
MRRNNSRLFYVTERHWDSSEPASCVELLQDPDIRYAVKRVFSGNVQLPRLSCRPYAQERQQDGAPPEPAAPPTCSIRHSR
SLGTLTSCFDVENGLSVARSPLDAQTSSSSGLVLQANYPHSQRRESFLYRSDSDFDLSPKGPSRNLSSASDLHSEDMIVT
PFAQVLASLRTVRSNFALITGQQDRAASKTRSSGSHPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKTRHSVSEM
ASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIMSPPTKEKDKKKRPMSQISGVKKVTHSLIPSTIPRFG
VNASQEEFLAKELEDVDRWGLDIFKVAEYSGKRPLTVTMYTIFQERDLLKTFKIPVDHFINFMMTLEDHYRSDVAYHNNI
HAADVVQSTHVLLSTPALEAVFTDLEILAALFASSIHDVDHPGVSNQFLINTNSELALMYNDLSVLENHHLAVGFKLLQE
DNCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPT
KPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNR
EWYQSMIPRSPSPRPHDQGGRGSLEEASVLGEVPGSMTTEKFQFALTLEEEGESDMEGSPREEKGSRSLTKHSGVFDSGS
IPTRRLNKILTSDSGRTFSLDSEKDMAEDRETDPEGPSVVPRFRLGT
>gi|658844801|ref|XP_008404825.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X8 [Poecilia reticulata]
MEVCSFDVENGLSVGRSPLDSQTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNW
LPRHGEDMIVTPFAQVLASLRTVRSNVAALTHLQDRVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLET
LQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDLEILSPPSKEKEKKKRPMSQISGVKKATQS
PSLAPACIPRFGVNTPHESMLAKEIEDLNRWGMDIFKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLED
HYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLEN
HHLAVGFKLLQEENCDIFQNLSKKQKDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQ
NMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPD
AQDILDTLEDNREWYQSMIPRSPSPTSPDEPHAEVGPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEDEEEAESDLESPL
EEESLTSGDRRHDSSSPSLSPDPRGGGSSRYRPPSPHPSRTLSLASMSVRSPHPHRTLDSPGPEASDRNRELSQEGDGVA
CLRMGT
>gi|2706889|gb|AAB96876.1| PDE4C-426 [Homo sapiens]
MSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNQPLTAIIFSIFQERDLLKTFQIP
ADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSE
LALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVL
LLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAH
PLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEAL
ELPDTELLSPEAGPDPGDLPLDNQRT
>gi|42475542|ref|NP_963901.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Mus musculus] >gi|21410862|gb|AAH30873.1| Phosphodiesterase 4C, cAMP specific [Mus musculus] >gi|148696917|gb|EDL28864.1| phosphodiesterase 4C, cAMP specific, isoform CRA_b [Mus musculus]
MRRSGTALSFLWTERVREPVDSGVAPVSPLGGGVILRRFSGTLLLPPLSSRLGSSGEAESAAHVVFTIGTQGTQRNLGSA
QSSFDLENGLPGGKGLLDAQSGPSLGRALQPPVHHVQRRESFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQV
LASLRTVRNNVAALAHGPGSATRQVLLGTPPHSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFK
RMLNRELSYLSETSRSGNQVSEYISQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQ
LAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQS
AHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRN
LSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQQGDRERESGLDISPMCDKHTASM
EKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQSRIPCSPPHTMGSDRFKFELTLEEAEEEEEEEDEGQCT
ALNRESSELPST
>gi|617508638|ref|XP_007542323.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X3 [Poecilia formosa]
MRTLKKLWRGGRPDRTKQTRKRSGFYRDESGHKLRSTKRGRTAEWPRRGSFDVENGLSVARSPLDAQSSSSSGLVLQANY
PHSQRRESFLYRSDSDFDLSPKGPSRNLSSASDLHSEDMIVTPFAQVLASLRTVRSNFALITGQQDRAASKTRSSGSHPP
SMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKTRHSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKP
DDMDIMSPPTKEKDKKKRPMSQISGVKKVTHSLVPSTIPRFGVNASQEEFLAKELEDVDRWGLDIFKVAEYSGKRPLTVT
MYTIFQERDLLKTFKIPVDHFINFMMTLEDHYRSDVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASSIHD
VDHPGVSNQFLINTNSELALMYNDLSVLENHHLAVGFKLLQEDNCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNLLA
DLKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKH
NASIEKNQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPRPHGQGGRGSLEEASVPGEGPGSMM
AEKFQFALTLEEEGESDTEGSPREEKGSRSLTKHSGAFDSGSIPTRRLNKILTSDSGRTFSLDSENDMAEDRETDPEGPS
VVPRFRLGT
>gi|658844787|ref|XP_008404818.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Poecilia reticulata]
MLQRGAERRQEPRSRGTLAGGGGGQLVETEAEGELTGIAEMSLPTNCMYLAPSVQDRCFKVRSGNICGSPCAVNRPIDIV
QKRRRFDVENGLSVGRSPLDSQTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNW
LPRHGEDMIVTPFAQVLASLRTVRSNVAALTHLQDRVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLET
LQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDLEILSPPSKEKEKKKRPMSQISGVKKATQS
PSLAPACIPRFGVNTPHESMLAKEIEDLNRWGMDIFKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLED
HYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLEN
HHLAVGFKLLQEENCDIFQNLSKKQKDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQ
NMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPD
AQDILDTLEDNREWYQSMIPRSPSPTSPDEPHAEVGPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEDEEEAESDLESPL
EEESLTSGDRRHDSSSPSLSPDPRGGGSSRYRPPSPHPSRTLSLASMSVRSPHPHRTLDSPGPEASDRNRELSQEGDGVA
CLRMGT
>gi|658844793|ref|XP_008404821.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X4 [Poecilia reticulata]
MECATLSREGAGLAKPPKHLWRQPRTHIRIKQRFNSDTERYLCRNRTLEKLRPGLKKPRMSWPSSLRRFDVENGLSVGRS
PLDSQTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVL
ASLRTVRSNVAALTHLQDRVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLETLQTRHSVSEMASNKFKR
MLNRELTQLSETSRSGNQVSEFIASTFLEKQHDLEILSPPSKEKEKKKRPMSQISGVKKATQSPSLAPACIPRFGVNTPH
ESMLAKEIEDLNRWGMDIFKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNNIHAADV
VQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLSKKQKDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEL
YRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
MIPRSPSPTSPDEPHAEVGPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEDEEEAESDLESPLEEESLTSGDRRHDSSSP
SLSPDPRGGGSSRYRPPSPHPSRTLSLASMSVRSPHPHRTLDSPGPEASDRNRELSQEGDGVACLRMGT
>gi|658844789|ref|XP_008404819.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Poecilia reticulata]
MSRFQNRRESLPAAQQVVRRRFSGPLLLPPLWRRHSCHDQHPRETRRPSAINVIPLDRLQEIYSQALASRDELRFDVENG
LSVGRSPLDSQTSPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVT
PFAQVLASLRTVRSNVAALTHLQDRVVNKRPSSASQPPLCKPCLSEEPYQKLTMETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDLEILSPPSKEKEKKKRPMSQISGVKKATQSPSLAPACIPRF
GVNTPHESMLAKEIEDLNRWGMDIFKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLSKKQKDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSMIPRSPSPTSPDEPHAEVGPAAGTPGSGGAFPSSGGDKFQFELTLEEEEEDEEEAESDLESPLEEESLTSGDRR
HDSSSPSLSPDPRGGGSSRYRPPSPHPSRTLSLASMSVRSPHPHRTLDSPGPEASDRNRELSQEGDGVACLRMGT
>gi|542231034|ref|XP_005454080.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Oreochromis niloticus]
MSLPTNCVYLTPSVQDRYFKMRNGNICGSPCAVNRPIDIVQKRRRFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQR
RESFLYRSDSDFDLSPKTMSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNK
RPSSSNQPPMCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFI
ANTFLEKQHDVEILSPPPKEKEKKKRPMSQISGVKKATQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAE
YSGNRPLTVTMYTIFQERDLLKTFEIPVDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEII
AALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLAT
DMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKEHFTQGDRERDRG
MEISPMCDKHNASIEKTQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHHAEVGPAAV
GAGAPIPSGGGGGDKFQFELTLEEEEEEDEEADSDLESPIEDQSQSAGERHRDSSPPSLAPDPRSSSGSRYRPPSPHPSR
TLNLAAMSVRSPNPHRALASPGREGVDRDRELSQEGDGVACLRLGT
>gi|3688083|gb|AAC83049.1| PDE4C-426 [Homo sapiens] >gi|119605085|gb|EAW84679.1| phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila), isoform CRA_e [Homo sapiens]
MSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIP
ADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSE
LALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVL
LLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAH
PLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEAL
ELPDTELLSPEAGPDPGDLPLDNQRT
>gi|528493552|ref|XP_005172887.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Danio rerio]
MECSALSREGAGLAKPPKHLWRQPRTHIRIKQRYHSDTERYLCCNKATEKNRPGLKKPRMSWPSSFHKRFDVENGLSMGR
SSLDPSPSSGLVLQANSQRRESFLYRSDSDFDLSPKTMSRNSSTASELHGEDMIVTPFAQVLASLRTVRGNVAALTHMQD
RSNKRPSGTNPQSACKTNLSDEAYQKLTVETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQV
SEFIASTILQKQYDVELLSAACKEEKKRRPMSQISGVRKLSPSPSLPPTCIPRFGVNTQHESLLAKELEDLDRWGIDIFK
IAEYSGNRPLTVMMYTIFQERDLLKTFKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDL
EIMAALFASAIHDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFCNLSKKQRQSLRQMTIDMV
LATDMSKHMNFLADLKTMVETKKVTSQGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFSQGDRER
DKGIDVSPMCDKHTASMENTQVGFIDYIIHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPTPEEQDSRPTGV
TGSAGEKFQFELTLEEEDGELETEEEHTDIERSRTMTDPEHPQTSPLGITTILDSSERELDQELTSVSALQLETSSSSTH
E
>gi|332233639|ref|XP_003266011.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 7 [Nomascus leucogenys] >gi|397514348|ref|XP_003827451.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 5 [Pan paniscus] >gi|426384636|ref|XP_004058865.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 6 [Gorilla gorilla gorilla] >gi|441658512|ref|XP_004091264.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Nomascus leucogenys]
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELD
WCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQIS
GVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLI
TYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMY
NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNY
SDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWET
WADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDS
KTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|410921866|ref|XP_003974404.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Takifugu rubripes]
MECGGLSREGAGLAKPPKHLWRQPRTHIRIKQRFNSDNERYLCRNRTLEKLRPGLKKPRMSWPSSVKRFDVENGLSVGRS
PLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRGNFVALT
HLQDRVGNKRQTGSNQPPVCKPCVTAFAEEPCPKLALETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSE
TSRSGNQVSEFIANTFLEKQHDVEILSPPPKEREKKKRPMSQISGVKKVIPSLASVSIPRFGVNTPQESQLAKELEEINR
WGLDMFKISEFSGNRPLTVIMYSVFQERDLLKTFKIPVGTFVTFVMTLEDHYHGDVAYHNNIHAADVVQSTHVLLSTPAL
EAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQKDSLR
KMVIDMVLATDMSKHMNYLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNIVHCADLSNPTKPLELYRRWTDRIMREFF
TQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPSSPEH
DAKGSGGEAVAAGEAVPLGGGGDKFQFELTLEEEEEDEVESELESQKESGEEWHQDSPPASSPDPCRYRPPSPHPVRTMN
RITMSVQSPHRLRGSVGQESTDRDGELNQEREGVEHPRTGT
>gi|641698310|ref|XP_008137622.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Eptesicus fuscus]
MKKSRSVMTVTADDNVKDYFECTLSKSYSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPDGDGISRPTTLPLTT
LPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHG
DDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYRS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLN
NTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHS
DVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVH
CADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDI
LDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPESRDSLGE
TDVDNAAEDKSPVDT
>gi|433347|gb|AAC13745.1| 3',5'-cyclic AMP phosphodiesterase [Homo sapiens] >gi|741032|prf||2006290A cAMP phosphodiesterase
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELD
WCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQIS
GVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLI
TYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMY
NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNY
SDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFPQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWET
WADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDS
KTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|657738741|ref|XP_008330398.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Cynoglossus semilaevis]
MSLPNSCMFPVVHSVQDRYFKARNGNVCGSPCAVNRPIDIVQKRRRFDVENGLSVGRSPLDCQTSPGSGLVLQANYPHSQ
RRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNVAALTHLQDRVGNRRPSGSNQPSLCKP
CLAEEPYQKLAVETLEELDWCLDQLETLQTRNSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIANTFLEKQHDVEI
LSPPIKEKEKKKRPMSQISGVKKATQSPSLANACIPRFGVKAPNESMLGKEIEDINRWGLDIFKIAEYSGNRPLTVVMYS
VFQERDLLKTFKIPADTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIMATLFASAIHDVDH
PGVTNQFLIDTSSELAVMYNDTSVLENHHLAVGFKLLQEDNCDIFQNLSKKLRDSLRKMVIDMVLATDMSKHMNFLAGMK
TMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRITVEFFTQGDRERDKGMEISAMCDKHNAS
IEKNQVGFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSSPEEHHCEGEPGGGGGGGGGSVHSGGG
GGSGGDKFQFELTLEEEEEEEEEESDPESPLEEESQSGGERHHDSSSSPSLSPDPRRSNTRYRPPSPHPPRTLSLAAMSM
QSPHCHKALDSQEQGESDGDGELSREGEEVVCLCMDT
>gi|617508635|ref|XP_007542322.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X2 [Poecilia formosa]
MSVPANYGFFYSVERSITVRSGNIRGSPCAVNRPMDIINKRRRFDVENGLSVARSPLDAQSSSSSGLVLQANYPHSQRRE
SFLYRSDSDFDLSPKGPSRNLSSASDLEESLKHWEVNWLSSRHSEDMIVTPFAQVLASLRTVRSNFALITGQQDRAASKT
RSSGSHPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKTRHSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFI
SSTFLEKPDDMDIMSPPTKEKDKKKRPMSQISGVKKVTHSLVPSTIPRFGVNASQEEFLAKELEDVDRWGLDIFKVAEYS
GKRPLTVTMYTIFQERDLLKTFKIPVDHFINFMMTLEDHYRSDVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAA
LFASSIHDVDHPGVSNQFLINTNSELALMYNDLSVLENHHLAVGFKLLQEDNCDIFQNLSKKQRQSLRKMVIDMVLATDM
SKHMNLLADLKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGME
ISPMCDKHNASIEKNQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPRPHGQGGRGSLEEASVP
GEGPGSMMAEKFQFALTLEEEGESDTEGSPREEKGSRSLTKHSGAFDSGSIPTRRLNKILTSDSGRTFSLDSENDMAEDR
ETDPEGPSVVPRFRLGT
>gi|507632295|ref|XP_004699418.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Echinops telfairi]
MKKSRSVMTVAADDNVKDYFEGSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQTERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLQGTASRRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKRQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGHEKEGEGRHYFSSTKTLCVINPENRDSLG
ETEVDIATEDKSPVDT
>gi|658897704|ref|XP_008431687.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Poecilia reticulata]
MRRNNSRLFYVTERHWDSSEPASCVELLQDPDIRYAVKRVFSGNVQLPRLSCRPYAQERQQDGAPPEPAAPPTCSIRHSR
SLGTLTSCFDVENGLSVARSPLDAQTSSSSGLVLQANYPHSQRRESFLYRSDSDFDLSPKGPSRNLSSASDLEESLKHWE
VNWLSSRHSEDMIVTPFAQVLASLRTVRSNFALITGQQDRAASKTRSSGSHPPSMCKTSLAEEPHQQLAIETLDELDWCL
DQLDTLKTRHSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIMSPPTKEKDKKKRPMSQISGVK
KVTHSLIPSTIPRFGVNASQEEFLAKELEDVDRWGLDIFKVAEYSGKRPLTVTMYTIFQERDLLKTFKIPVDHFINFMMT
LEDHYRSDVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASSIHDVDHPGVSNQFLINTNSELALMYNDLSV
LENHHLAVGFKLLQEDNCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTNLGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIVHPLWETWADLV
HPDAQEILDTLEDNREWYQSMIPRSPSPRPHDQGGRGSLEEASVLGEVPGSMTTEKFQFALTLEEEGESDMEGSPREEKG
SRSLTKHSGVFDSGSIPTRRLNKILTSDSGRTFSLDSEKDMAEDRETDPEGPSVVPRFRLGT
>gi|634828642|ref|XP_007957428.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Orycteropus afer afer]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSKVNLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGHEKEGEGHNYFSSTKTLCVIDSENRDSLD
DTDVEIATEDKSPIDT
>gi|657738737|ref|XP_008330383.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Cynoglossus semilaevis]
MSCLENRRDSLPVVLQVVRRRFSGPLVLPPLWRRHSCHEHALTLDQLEVLYHRAVTSHDAHRFDVENGLSVGRSPLDCQT
SPGSGLVLQANYPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNVAALTHLQDRV
GNRRPSGSNQPSLCKPCLAEEPYQKLAVETLEELDWCLDQLETLQTRNSVSEMASNKFKRMLNRELTQLSETSRSGNQVS
EFIANTFLEKQHDVEILSPPIKEKEKKKRPMSQISGVKKATQSPSLANACIPRFGVKAPNESMLGKEIEDINRWGLDIFK
IAEYSGNRPLTVVMYSVFQERDLLKTFKIPADTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDL
EIMATLFASAIHDVDHPGVTNQFLIDTSSELAVMYNDTSVLENHHLAVGFKLLQEDNCDIFQNLSKKLRDSLRKMVIDMV
LATDMSKHMNFLAGMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRITVEFFTQGDRER
DKGMEISAMCDKHNASIEKNQVGFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSSPEEHHCEGEP
GGGGGGGGGSVHSGGGGGSGGDKFQFELTLEEEEEEEEEESDPESPLEEESQSGGERHHDSSSSPSLSPDPRRSNTRYRP
PSPHPPRTLSLAAMSMQSPHCHKALDSQEQGESDGDGELSREGEEVVCLCMDT
>gi|617508632|ref|XP_007542320.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X1 [Poecilia formosa]
MRTLKKLWRGGRPDRTKQTRKRSGFYRDESGHKLRSTKRGRTAEWPRRGSFDVENGLSVARSPLDAQSSSSSGLVLQANY
PHSQRRESFLYRSDSDFDLSPKGPSRNLSSASDLEESLKHWEVNWLSSRHSEDMIVTPFAQVLASLRTVRSNFALITGQQ
DRAASKTRSSGSHPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKTRHSVSEMASNKFKRMLNRELSQLSETSRSG
NQVSEFISSTFLEKPDDMDIMSPPTKEKDKKKRPMSQISGVKKVTHSLVPSTIPRFGVNASQEEFLAKELEDVDRWGLDI
FKVAEYSGKRPLTVTMYTIFQERDLLKTFKIPVDHFINFMMTLEDHYRSDVAYHNNIHAADVVQSTHVLLSTPALEAVFT
DLEILAALFASSIHDVDHPGVSNQFLINTNSELALMYNDLSVLENHHLAVGFKLLQEDNCDIFQNLSKKQRQSLRKMVID
MVLATDMSKHMNLLADLKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDR
ERDKGMEISPMCDKHNASIEKNQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPRPHGQGGRGS
LEEASVPGEGPGSMMAEKFQFALTLEEEGESDTEGSPREEKGSRSLTKHSGAFDSGSIPTRRLNKILTSDSGRTFSLDSE
NDMAEDRETDPEGPSVVPRFRLGT
>gi|554547076|ref|XP_005868093.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Myotis brandtii] >gi|558129627|ref|XP_006089851.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Myotis lucifugus]
MKKSRSVMTVTADDNVKDYFECTLSKSYSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPDGDGISRPTTLPLTT
LPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHG
DDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPAASQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTYRS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLN
NTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHS
DVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVH
CADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDI
LDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPESRDSLGE
TDVDNAAEDKSPVDT
>gi|548460099|ref|XP_005678360.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Capra hircus]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSGRARTPEGDGISRPTTLPLM
TLPSIAITTVTQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPAAGQPSVSRVNLPEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
ADVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKDGEGHSYFGNTKTLCVIDPENRDPLG
KTEVDITTEDKSPSDT
>gi|291398747|ref|XP_002715986.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Oryctolagus cuniculus]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSAGRSPLDPQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPAASQTPVSRASLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEGNRDCQGLMEKFQFELTLEEEDSEGPEKEAEGHSYFSSTKTLCVIDPENRDLLG
ETDVSIATEDKSPVDT
>gi|524940647|ref|XP_005072258.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Mesocricetus auratus]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFSSTKTLCVIDPESRDSLE
DTDIDITTEDKSPIDT
>gi|511931652|ref|XP_004784839.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Mustela putorius furo] >gi|511931654|ref|XP_004784840.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Mustela putorius furo]
MKKSRSVMAVTADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTSSKRSPAAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSS
LNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHY
HSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNM
VHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQ
DILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKEGEGHNYFSSTKTLCVIDPDHRDSL
GETDGDTGAEDKSPIDT
>gi|466063295|ref|XP_004280820.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like isoform 1 [Orcinus orca]
MKKSRSVMTVTADDNVKDYFECNLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSGRARTPEGDGISRPTTLPLV
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTPNKRSPAASQPSVSRVNLPEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
ADVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFSNTKTLCVIDPENRDSLG
ETDVDITTEDKSPIDT
>gi|426215682|ref|XP_004002099.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Ovis aries]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSGRARTPEGDGISRPTTLPLM
TLPSIAITTVTQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPAAGQPSVSRVNLPEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
ADVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKDGEGHSYFGSTKTLCVIDPENRDPLG
KTEVDITTEDKSPSDT
>gi|395730396|ref|XP_002810770.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B [Pongo abelii]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
ALPSIAITTVSQDCFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPSVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKMLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>gi|635107536|ref|XP_007976613.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Chlorocebus sabaeus] >gi|635107538|ref|XP_007976614.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Chlorocebus sabaeus]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAGSQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>gi|594619275|ref|XP_007164375.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Balaenoptera acutorostrata scammoni]
MKKSRSVMTVTADDNVKDYFECNLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSGRARTPEGDGISRPTTLPLV
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTSNKRSPAASQPSVSRVNLPEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRILNRELTHLSEMSRSGNQESEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSIARFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
ADVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFGNTKTLCVIDPENRDSLG
ETDVDITTEDKSPIDT
>gi|532019751|ref|XP_005353529.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Microtus ochrogaster]
MKKSRSVMAVTADDNGKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEADGICRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFGSTKTLCVIDPESRDSLE
ETDIDIATEDKSPIDT
>gi|344279040|ref|XP_003411299.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Loxodonta africana]
MKKSRSVMTVTADDHVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSESARTPDGDGISRPTTLPLT
TLPSIAITAVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVSTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERNRDCQGLMEKFQFELTLEEEDSEGHEKEGEGHNYFSSTKTLCVIHPENRDSLE
ETDVEIATEDKSPIDT
>gi|32171241|ref|NP_002591.2| cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Homo sapiens] >gi|82799486|ref|NP_001032418.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Homo sapiens] >gi|729163|sp|Q07343.1|PDE4B_HUMAN RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4B; AltName: Full=DPDE4; AltName: Full=PDE32 [Homo sapiens] >gi|347122|gb|AAA03589.1| phosphodiesterase [Homo sapiens] >gi|75517091|gb|AAI01481.1| Phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) [Homo sapiens] >gi|85397153|gb|AAI05041.1| Phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) [Homo sapiens] >gi|158260961|dbj|BAF82658.1| unnamed protein product [Homo sapiens] >gi|307685577|dbj|BAJ20719.1| phosphodiesterase 4B, cAMP-specific [synthetic construct] >gi|608785439|gb|AHW56556.1| phosphodiesterase 4B cAMP-specific isoform A, partial [Homo sapiens] >gi|649120373|gb|AIC54878.1| PDE4B, partial [synthetic construct]
MKKSRSVMTVMADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSAGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>gi|397470779|ref|XP_003806990.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Pan paniscus] >gi|397470781|ref|XP_003806991.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 3 [Pan paniscus]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQNERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSAGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>gi|504153586|ref|XP_004588796.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Ochotona princeps]
MKKSRSVMTVTADDNAKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQHERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPATSQPPVSRASLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDSENRDLLG
ETDVNIATEDKSPVDT
>gi|478514532|ref|XP_004431516.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Ceratotherium simum simum] >gi|478514534|ref|XP_004431517.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Ceratotherium simum simum]
MKKSRSVMTVTADDNIKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGVSRPTTLPLT
SLPSIAITTVSQERFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNLQEDSYQKLAMETLDELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRDWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDVDIATEDKSPIDT
>gi|426329919|ref|XP_004025978.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Gorilla gorilla gorilla] >gi|426329921|ref|XP_004025979.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 3 [Gorilla gorilla gorilla]
MKKSRSVMTVTADDTVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>gi|332232112|ref|XP_003265246.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 4 [Nomascus leucogenys]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKCPVDT
>gi|16930143|gb|AAL31763.1|AF202732_1 cAMP-specific phosphodiesterase isoform PDE4B1 [Rattus norvegicus] >gi|149044591|gb|EDL97850.1| phosphodiesterase 4B, cAMP specific, isoform CRA_a [Rattus norvegicus]
MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNKRSPAASQAPVTRVSLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGPNYFSSTKTLCVIDPENRDSLE
ETDIDIATEDKSLIDT
>gi|488597122|ref|XP_004483730.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Dasypus novemcinctus]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNALGIDLWRGRRCCSGNLQLPPLSQRQNEKARTPEGDGICRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAAGQPPVSRANLPEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERNRDCQGLMEKFQFELTLEEEDSEVSEKHGEGHNYFSSTKTLCVIDPESRDSLG
ETDEEIVTEDKSPVDT
>gi|667273090|ref|XP_008571548.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Galeopterus variegatus]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQGERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFMVLTNLHGTSNKRSPAASQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLIEKFQFELTLEEEDSEGPEKEGEGHNYFSSTKTLCVIDPENKDSLE
ETDIDTVTEDKSPVDT
>gi|512958520|ref|XP_004841562.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X6 [Heterocephalus glaber]
MKKSRSVMTVTADDNVRDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSDRARTPEGDGLCRPTTLPLT
TLPSIAITTASQEGFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLQGASNKRSPATSQPPVSRVNPQEEPYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
ADVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERNRDCQGLIEKFQFELTLEEDDSEGPEKEGAGHSYFGSTKTLCVIDPENRDPLG
ETDVDTATEDKSPTDT
>gi|194097391|ref|NP_001123491.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Sus scrofa] >gi|167966198|gb|ACA13180.1| phosphodiesterase 4B cAMP-specific isoform 1 [Sus scrofa]
MKKSRSVMTVTADDNVKDDFECSLSKSYSSSSNTLGIDLWRGRRCCSGTLQLPPLSQRQSGRARTPEGDGISRPTTLPLM
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTSNKRSPAASQPPVSRVNLPEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTLVTYMMTFEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHGYFGSTKTLCVIDPENRDSLG
ETGVDTATEDKSPTDT
>gi|505796948|ref|XP_004607147.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Sorex araneus]
MKKSRSVMTVTADDSAKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERTRSPEGDGICRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDAQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLQGTSNKRSPATSQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSNTKTLCVIEPEHQDSLG
ETDGDGTTEDKTPTDT
>gi|403257846|ref|XP_003921503.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Saimiri boliviensis boliviensis] >gi|403257848|ref|XP_003921504.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 3 [Saimiri boliviensis boliviensis]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDTSPVDT
>gi|332809335|ref|XP_001162471.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 4 [Pan troglodytes] >gi|332809337|ref|XP_001162426.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 3 [Pan troglodytes]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQNERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSAGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>gi|152031653|sp|P14646.4|PDE4B_RAT RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4B; AltName: Full=DPDE4 [Rattus norvegicus]
MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRIVRNNFTLLTNLHGAPNKRSPAASQAPVTRVSLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGPNYFSSTKTLCVIDPENRDSLE
ETDIDIATEDKSLIDT
>gi|537255384|gb|ERE88996.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like protein [Cricetulus griseus]
METSGVGRAGVPRAPNHLWRQPRRPIRIQRRFHSDPEPSERPALVKSRRSWPSSFHRRFDLENGFASSRGPLDPQSGRVL
QPPGQHGLRRESFLYRSESDHEPSPKAVSRNSSVASDVHGEDMIVTPFAQVLASLRTVRSNVAALAHGPGSRSWGPLPVA
ASLPPPQFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQQAEVELPRLPREDTRPMSQISALRGPRPTGLPTAAVPRFG
VQTDQEGQLAKELEDTNKWGLDVFKVAQLSGNRPLTAIMFSVLQERDLLKTFRIPADTLLAYLLMLEGHYHADVAYHNSV
HAADVAQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDVSVLENHHLAVGFKLLQA
ENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPT
KPLQLYRQWTNRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNR
EWYQSRIPCSPSHTMGQHCSGPDKFQFELTLEEAEEEENEGQAQH
>gi|568928605|ref|XP_006502918.1| PREDICTED: phosphodiesterase 4B isoform X1 [Mus musculus]
MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQAGSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLE
ETDIDIATEDKSPIDT
>gi|544405393|ref|XP_005543190.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X2 [Macaca fascicularis] >gi|355558083|gb|EHH14863.1| hypothetical protein EGK_00854 [Macaca mulatta] >gi|355745352|gb|EHH49977.1| hypothetical protein EGM_00727 [Macaca fascicularis]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>gi|296208178|ref|XP_002750971.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Callithrix jacchus]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEREGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDTSPVDT
>gi|617625040|ref|XP_007528296.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Erinaceus europaeus]
MKKSRSVMTVTADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRFCSGSLQLPPLSQRQSERARTPEGDGICRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTANKRSPAASQPPVTRVNLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYALFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQSRDCQGLMEKFQFELTLEEEDSEGPEKEGERHSYFSSTKMLCVIDPEHRDSPG
KTDGDVATEGKSPTDT
>gi|532093526|ref|XP_005332443.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Ictidomys tridecemlineatus]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLM
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFSSTKTLCVIDPGNRDSLG
ETDDVDIVTEDKSPIDT
>gi|402854839|ref|XP_003892060.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Papio anubis] >gi|402854841|ref|XP_003892061.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Papio anubis]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSTTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>gi|533141341|ref|XP_005385351.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Chinchilla lanigera]
MMRKSRSVVTVTAGDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSDRARTPEGDGLCRPTTLPL
TTLPSIAITTVSQECFDVENGPSPGRSPLDPQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQ
HGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGASNKRSPAASQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSS
LNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHY
HSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVASSGVLLLDNYTDRIQVLRNM
VHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQ
DILDTLEDNRNWYQSMIPQSPSPPLEERSRDCPGLVEKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDLL
GETDVDPATEDKSPVDT
>gi|560929827|ref|XP_006191061.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Camelus ferus]
MKKSRSVMTVTADDTVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSGRARTPEGDGISRPTTLPLM
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHSTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
PDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFGSTKTLCVIDPENRDSLG
ETDVDTATEDKSLIDT
>gi|597762444|ref|XP_007245191.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Astyanax mexicanus]
MNKDSRFPRKTSGYSTRRHSCIGFDAENGLCLGRSSMEPQGGSGVVLQASVPHNQRRESFLYRSDSDFDLSPKATSRNSS
TASELHGEDMIVTPFAQVLASLRTVRNNFAILTCQQDRVPSKRSSGTPTMCKTSLPEEPVPKLAVETLDELDWCLEQLET
LKTRNSVSQMASNKFKRMLSRELTQLSETSRSGNQVSEYISSTFLEKQHDLELMSLPSKEKENKKRPMSQICGLKKPKST
PNRSVSIPRFGVSTNQEELLAKELEDIHRWGVDIFKISKYSGNRPLTVTMYSIFQERDLLKMFKIPADTFITFMMALEEN
YRSDVAYHNSIHAADVVQSTNVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENH
HLAVGFKLLQEENCDIFQNLSKKQRQSLRKIVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQN
MVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERERGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDA
QDILDTLEDNREFYQSLIPHSPSAVLEEKSLGRGASGGSGVGSGGAAGEKFQIVLTLEEEEGETDAESPEEEVESGHGWV
RNAPGWKAGQRSDREDEDEDEGGDGELHRGGRNIPRQRSGT
>gi|560966095|ref|XP_006205441.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Vicugna pacos]
MKKSRSVMTVTADDTVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSGRARTPEGDGISRPTTLPLM
TLPSIAITTVSQECFDVENGPSPGRSPLDPQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTSNNPAEGRRLPTCNFPNLRKMSLTEESYQKLAMETLEELDWCLDQLET
IQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLM
HSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTL
EDHYHPDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVL
ENHHLAVGFKLLQEEHCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQV
LRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQ
PDAQDILDTLEDNRNWYQSMIPQSPSPPLEEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHSYFGSTKTLCVIDPED
RDSLGETDVDIATEDKSPIDT
>gi|472385103|ref|XP_004411917.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Odobenus rosmarus divergens] >gi|472385105|ref|XP_004411918.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 2 [Odobenus rosmarus divergens]
MKKSRSVMAVAADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLR
TLPSIAITTVSQECFDVENGPCPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGASNKRSPAAATQPSVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSS
LNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHY
HSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNM
VHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQ
DILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKEGEGHNYFSSTKTLCVIDPDHRDLL
GETDGDTGAEDKSPIDT
>gi|664721480|ref|XP_008517792.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Equus przewalskii]
MKKSRSVMAVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGVPRPTTLPLT
TLPSIAITTVSQERFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVHLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPESRDSLG
ETGVDMATEDKSPIDT
>gi|545198941|ref|XP_005604177.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [Equus caballus]
MASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPRVTPTEPPKPISQISGLRGLPHSASLSAATFPRFG
VQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLVTYLLTLEGHYRADVAYHNSL
HAADVAQSTHVLLATPALQAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQA
ENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVASLGVLLLDNYSDRIQVLQNLVHCADLSNPT
KPLPLYRQWTDRIMAEFFQQGDRERESGLDVSPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNR
EWYQSKVPRSPMDPTSPEQGSPDRFQFELTLDEAEEEKEAEEEGALDGEASESPDTELLSPEASLDPGGLLLDNQRTAGK
PCKNHEGGVMAEPFGN
>gi|537255383|gb|ERE88995.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like protein [Cricetulus griseus]
METSGVGRAGVPRAPNHLWRQPRRPIRIQRRFHSDPEPSERPALVKSRRSWPSSFHRRFDLENGFASSRGPLDPQSGRVL
QPPGQHGLRRESFLYRSESDHEPSPKAVSRNSSVASDVHGEDMIVTPFAQVLASLRTVRSNVAALAHGPGRYCGRGLEAW
GLLGVEFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQQAEVELPRLPREDTRPMSQISALRGPRPTGLPTAAVPRFGV
QTDQEGQLAKELEDTNKWGLDVFKVAQLSGNRPLTAIMFSVLQERDLLKTFRIPADTLLAYLLMLEGHYHADVAYHNSVH
AADVAQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDVSVLENHHLAVGFKLLQAE
NCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTK
PLQLYRQWTNRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNRE
WYQSRIPCSPSHTMGQHCSGPDKFQFELTLEEAEEEENEGQAQH
>gi|507556025|ref|XP_004661778.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Jaculus jaculus]
MMKKSRSVMAVTADYNIKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGSLQLPPLSQRQSERARTPEGDGISRPTTLPL
ATLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQ
HGDDLIVTPFAQVLASLRSVRNNFTLLTNLQGAPNKRSPATSQAPISRVSLQEESYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLSRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPAPTPKDREKKKKQLMTQISGVKKLMHSSSL
NNTSISRFGVSTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQSLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERNRDCQGLMEKFQFELTLEEEDCEGPEKEGEGHSYFSNTKTLCVIDPESRGSLG
KTDINITTEDKSPINT
>gi|149709503|ref|XP_001500350.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform 1 [Equus caballus]
MKKSRSVMAVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGVPRPTTLPLT
TLPSIAITTVSQERFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVHLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPESRDSLG
ETGVDMATEDKSPVDT
>gi|530621010|ref|XP_005300145.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Chrysemys picta bellii] >gi|530621012|ref|XP_005300146.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Chrysemys picta bellii] >gi|530621014|ref|XP_005300147.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Chrysemys picta bellii]
MKKSRSVMTVTADDIAKDYLECGLSKSYSTSSNMLGIDLWRGRRCCSCNLQLPPLSHRQSERAKTPDRDILARPTTLPLL
TPPSIAITTYQDSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQHG
DDLIVTPFAQVLASLRSVRNNFTLLTNLQGTSNKRSPAASQPPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLN
NTSISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHSRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHS
DVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLQEEHCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVH
CADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDI
LDTLEDNRNWYQSMIPQSPSPPLDERNRDCQGLMEKFQFELTLEEEDSDGPEKESESISYFSNTKTLCVIDPGNRESQEE
ANIEIVTEDMSPVDT
>gi|301776528|ref|XP_002923683.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like isoform 1 [Ailuropoda melanoleuca]
MKKSRSVMAVAADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGASNKRSPAAASQPIVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSS
LNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHY
HSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLTKRQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNM
VHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQ
DILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPDKEGEGHTYFSSTKTLCVIDPDHRDSL
GETDGDTGAEDKTPIDT
>gi|507936223|ref|XP_004679140.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Condylura cristata]
MKKSRSVMTVTADDNVRDYFECNLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERAKTPEGDGISRPTTLPLT
TLPSIAITTVSQECFDVENGPSPSRSPLDPQAGSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTSNKRSPAASQPPVSRVNLQEESYQKLAMDTLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLEEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFSSTKTLCVIDPEHRDSLR
ETEVDIETEDKSPIDT
>gi|589949156|ref|XP_006987236.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Peromyscus maniculatus bairdii]
MKKSRSVMAVTADDNVKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLT
TLPSIAITTVSQERFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISHFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFSSTKTLCVIDPESRDSLE
ETDIDIATEDKSPIDT
>gi|586463754|ref|XP_006862510.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like isoform X1 [Chrysochloris asiatica]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGLSRPTTLPLT
ALPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTSNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGHEKEEEGHNYFSSTKTLCVIDPENRDSLE
ETDVEIATEDKSPIDT
>gi|657738743|ref|XP_008330406.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Cynoglossus semilaevis]
MNKDQRSTRKVSQTGLGHGRRHSCVSFDVENGLSVGRSPLDCQTSPGSGLVLQANYPHSQRRESFLYRSDSDFDLSPKTM
SRNSSTASDLEDGLKNCEVNWPPRHGEDMIVTPFAQVLASLRTVRSNVAALTHLQDRVGNRRPSGSNQPSLCKPCLAEEP
YQKLAVETLEELDWCLDQLETLQTRNSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIANTFLEKQHDVEILSPPIK
EKEKKKRPMSQISGVKKATQSPSLANACIPRFGVKAPNESMLGKEIEDINRWGLDIFKIAEYSGNRPLTVVMYSVFQERD
LLKTFKIPADTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIMATLFASAIHDVDHPGVTNQ
FLIDTSSELAVMYNDTSVLENHHLAVGFKLLQEDNCDIFQNLSKKLRDSLRKMVIDMVLATDMSKHMNFLAGMKTMVETK
KVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRITVEFFTQGDRERDKGMEISAMCDKHNASIEKNQV
GFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSSPEEHHCEGEPGGGGGGGGGSVHSGGGGGSGGD
KFQFELTLEEEEEEEEEESDPESPLEEESQSGGERHHDSSSSPSLSPDPRRSNTRYRPPSPHPPRTLSLAAMSMQSPHCH
KALDSQEQGESDGDGELSREGEEVVCLCMDT
>gi|657738739|ref|XP_008330391.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Cynoglossus semilaevis]
MSLPNSCMFPVVHSVQDRYFKARNGNVCGSPCAVNRPIDIVQKRRRFDVENGLSVGRSPLDCQTSPGSGLVLQANYPHSQ
RRESFLYRSDSDFDLSPKTMSRNSSTASDLEDGLKNCEVNWPPRHGEDMIVTPFAQVLASLRTVRSNVAALTHLQDRVGN
RRPSGSNQPSLCKPCLAEEPYQKLAVETLEELDWCLDQLETLQTRNSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEF
IANTFLEKQHDVEILSPPIKEKEKKKRPMSQISGVKKATQSPSLANACIPRFGVKAPNESMLGKEIEDINRWGLDIFKIA
EYSGNRPLTVVMYSVFQERDLLKTFKIPADTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEI
MATLFASAIHDVDHPGVTNQFLIDTSSELAVMYNDTSVLENHHLAVGFKLLQEDNCDIFQNLSKKLRDSLRKMVIDMVLA
TDMSKHMNFLAGMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRITVEFFTQGDRERDK
GMEISAMCDKHNASIEKNQVGFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSSPEEHHCEGEPGG
GGGGGGGSVHSGGGGGSGGDKFQFELTLEEEEEEEEEESDPESPLEEESQSGGERHHDSSSSPSLSPDPRRSNTRYRPPS
PHPPRTLSLAAMSMQSPHCHKALDSQEQGESDGDGELSREGEEVVCLCMDT
>gi|557297218|ref|XP_006030934.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Alligator sinensis]
MKKSRSVMVVTADDNTKDYIESGLSKSYSTSSHSLGIDLWRGRRCCSGNLQLPPLSQRQSEKAKTPDRDIISRPTTLPLL
TPPSIAITILSEECFDVENGPSPGCSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSSKRSPAASQPPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDERNRDCQNLMEKFQFELTLEEEDSDGPEKEGDSISYFSNTKTLCMTDPGKRDSQR
EANIEIVTEDTSPVDT
>gi|564246995|ref|XP_006262605.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B [Alligator mississippiensis]
MKKSRSVMVVTADDNTKDYIESGLSKSYSTSSHSLGIDLWRGRRCCSGNLQLPPLSQRQSEKAKTPDKDIISRPTTLPLL
TPPSIAITSYHDCFDVENGPSPGCSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQHG
DDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSSKRSPAASQPPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLN
NTSISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHS
DVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVH
CADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDI
LDTLEDNRNWYQSMIPQSPSPPLDERNRDCQNLMEKFQFELTLEEEDSDGPEKEGDSISYFSNTKTLCMTDPGKRDSQRE
ANIEIVTEDTSPVDT
>gi|655839247|ref|XP_008260473.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Oryctolagus cuniculus]
MELLHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLE
TLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMH
SSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLE
DHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLE
NHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVL
QNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
DAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQD
SESTEIPLDEQVEEEAVGEEESQPEACVIDDYSPDT
>gi|657738735|ref|XP_008330375.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Cynoglossus semilaevis]
MSCLENRRDSLPVVLQVVRRRFSGPLVLPPLWRRHSCHEHALTLDQLEVLYHRAVTSHDAHRFDVENGLSVGRSPLDCQT
SPGSGLVLQANYPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLEDGLKNCEVNWPPRHGEDMIVTPFAQVLASLRTV
RSNVAALTHLQDRVGNRRPSGSNQPSLCKPCLAEEPYQKLAVETLEELDWCLDQLETLQTRNSVSEMASNKFKRMLNREL
TQLSETSRSGNQVSEFIANTFLEKQHDVEILSPPIKEKEKKKRPMSQISGVKKATQSPSLANACIPRFGVKAPNESMLGK
EIEDINRWGLDIFKIAEYSGNRPLTVVMYSVFQERDLLKTFKIPADTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHV
LLSTPALEAVFTDLEIMATLFASAIHDVDHPGVTNQFLIDTSSELAVMYNDTSVLENHHLAVGFKLLQEDNCDIFQNLSK
KLRDSLRKMVIDMVLATDMSKHMNFLAGMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTD
RITVEFFTQGDRERDKGMEISAMCDKHNASIEKNQVGFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSP
SPSSPEEHHCEGEPGGGGGGGGGSVHSGGGGGSGGDKFQFELTLEEEEEEEEEESDPESPLEEESQSGGERHHDSSSSPS
LSPDPRRSNTRYRPPSPHPPRTLSLAAMSMQSPHCHKALDSQEQGESDGDGELSREGEEVVCLCMDT
>gi|527266123|ref|XP_005151242.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Melopsittacus undulatus]
MKKSRSVMTVTADENALDYLECGLSKSYSTSSHALGIDLWRGRRCCSGNLQLPPLSQRQTEKAKTPDRDVVCRPTTLPLL
TPPSIAITTYQDCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQHG
DDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPATSQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTYRS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLN
NTSISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHS
DVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVH
CADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDI
LDTLEDNRNWYQSMIPQSPSPPLEERGRDCQGLMEKFQFELTLEEEDSDGPEKDGESIGYFSNTKTLSVAEPGEEDSQKE
ANIEIVTEDTSPVDT
>gi|488534366|ref|XP_004458896.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 9 [Dasypus novemcinctus]
MDLLHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLE
TLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMH
SSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQERELLKTFKIPVDTLITYLMTLE
DHYHADVAYHNYIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLE
NHHLAVGFKLLQEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVL
QNMVHCADLSNPTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
DAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQD
SESTEIPLDEQVEEEAVGEEESQPEACVIEDHSPDT
>gi|351711969|gb|EHB14888.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Heterocephalus glaber]
MEVIIRHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMT
LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGQQGQSEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEEESQPEVCVIDDCSPDT
>gi|512901157|ref|XP_004899415.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Heterocephalus glaber]
MKKSRSVMTVTADDNVRDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSDRARTPEGDGLCRPTTLPLT
TLPSIAITTASQEGFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTLLTNLQGASNKRSPATSQPPVSRVNPQEEPYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKNANLTRCKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKL
MHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMT
LEDHYHADVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESV
LENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQ
VLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLV
QPDAQDILDTLEDNRNWYQSMIPQSPSPPLDERNRDCQGLIEKFQFELTLEEDDSEGPEKEGAGHSYFGSTKTLCVIDPE
NRDPLSETDVDTATEDKSPTDT
>gi|556986312|ref|XP_005998710.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like isoform X1 [Latimeria chalumnae]
MKKSTSVLAMIADDNDKDPSDCGFSNSYTSTNTLGIDLWRGRRRYSGNLQLPPLSWRQAERAKTPERESPSRPTTLPFHA
APRIAITTQEQQCFDGPPPGHSPLDSQASPGSGLVLHSNFPGHSQRRESFLYRSDSDYDLSPKSMSRNSSIASELHGDDL
IVTPFAQVLASLRSVRNNFTMLTNLHGAPNKRSPATNQSPITRVSIPEESFQKIAMETLEELDWCLDQLETIQTYRSVSE
MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLTNSS
ISRYGVKTDQEDMLAKELEDLNKWGLNIFKVAEYACNRPLTCIMHAIFQERDLLKTFKIPVDTFVTYMMTLEDHYHADVA
YHNSLHAADVAQSTHILLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGF
KLLQEEECDIFQNLTKKQRQSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNFTDRIQVLRNMVHCAD
LSNPTKSLELYRQWTDRIMDEFFHQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNRNWYQSMIPQSPSPSPDEHGKDCQGPTEKFQFELTFEEEDSEGTEKEESSQGEDSSSCYSSEKKTLCVPRSQDLAF
EIESEIEIVTEDTSPLDT
>gi|530379374|ref|XP_005248597.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Homo sapiens]
MESLHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLE
TLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMH
SSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLE
DHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLE
NHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVL
QNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
DAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQD
SESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|327284161|ref|XP_003226807.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Anolis carolinensis] >gi|637348808|ref|XP_008117916.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Anolis carolinensis]
MKKSRSVMAVTTEGNAKDYLECGLSKSYSASSNTLGIDLWRGRRCCSGNLLLPPLSQRQSGSARTPDRENISRPTTLPLL
NLPSIAITTYQDSFDVENGPSPGRSPLDPQASSSSGLVLHTNFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQHG
DDLIVTPFAQVLASLRSVRNNFTLLTNLQGTSNKRSPSANQPPIPRVNIQEESYQKLAMDTLEELDWCLDQLETIQTYRS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLN
NTSISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHSRPLTCIMYAIFQERDLLKTFKISSDTFIAYMMTLEDHYHP
DVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVH
CADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDI
LDTLEDNRNWYQSMIPQSPSPPLEERSRDCQGLMEKFQFELTLEEEDSDGPEKEGDGISYFSSTKTLCVIDPGRRDSQRE
ADIEILEEDTSPIDT
>gi|525006047|ref|XP_005050697.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Ficedula albicollis]
MKKSRSVMTVTADENSLDYLECGLSKSYSTSSHALGIDLWRGRRCCSGSLQLPPLAQRQTELARSPEREPVCRPTTLPLL
PPPSIAITACHDCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQHG
DDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPATSQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTYRS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLN
NTSISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHS
DVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVH
CADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDI
LDTLEDNRNWYQSMIPQSPSPPLEERGQDCQGLMEKFQFELTLEEEDSDGPDKEGESLGYFSTTETLCTAQAGQEEPQRE
ATIEIVTEDTSPVDT
>gi|602698156|ref|XP_007461107.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [Lipotes vexillifer]
MASNKFKWMLNRELTHLSEASSSGNQVSEYISRTFLDQQTEVELPRVTPTEPPRPMSQISGLRGLPHSTSLSAATVPRFG
VQTDQEGQLAKELEDTKKWGLDVFKVAELSGNRPLTAIMFSIFQERDLLKTFRIPADTLATYLLTLEGHYHNDVAYHNSL
HAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDTSMLENHHLAVGFKLLQA
ENCDIFQNLTTKQRLSLRRMVIDMVLATDMSKHMNILADLKTMVETKKVTSLGVLLLDNYSDHIQVLQSLVHCADLSNPT
KPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNR
EWYQSKIPRSPVDPTSPKQGGPDRFQFQLTLQEAEEEEGEEEGALGGEASESPDTELLSPEASPDPGALYLDNQRTVGKP
CVNHEGNVMAEPLGT
>gi|514479138|ref|XP_003478875.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoformX2 [Cavia porcellus]
MMKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSDRARTPEADSICRPTTLPL
TTLPSIAITAVSQEGFDVENGPSPGRSPLDPQAGSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQ
HGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGATNKRSPATSQPPVSRVSLQEEPYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSS
LNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFITYMMTLEDHY
HSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVASSGVLLLDNYTDRIQVLRNM
VHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQ
DILDTLEDNRNWYQSMIPQSPSPPLEERSRDCQGLMEKFQFELTLEEEDSEGREKDGEGHGYFSSTKTLCVIDPESEDPL
GESDVDTATEDKSPTDT
>gi|586528873|ref|XP_006919355.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Pteropus alecto]
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLM
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTILTNLHGASNKRSPAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLKKKRADTSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEREGEGHNYFSSTKTLCVIDPENRDSLE
ETDVDIATEDKSPVDT
>gi|602636185|ref|XP_007424950.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Python bivittatus]
MKKSRSVMTVPTEGNTKDYLECRLSKSYSASSNTLGIDLWRGRRCCSGNLQLPPLSQRQSEKAKTPDNISRPTTLPLMTL
PSIAITTYQDSFDVENGPSPGRSPLDPQAGSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSVPSEQHGDD
LIVTPFAQVLASLRSVRNNFTILTNLQGTSNKRSPAANQLPVSKVNIQEESYQKLAMETLEELDWCLDQLETIQTYRSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNT
SISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHSRPLTCIMYAIFQERDLLKTFKISSDTFIAYMMTLEDHYHTDV
AYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVG
FKLLQEEHCDIFHNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCA
DLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILD
TLEDNRNWYQSMIPQSPSPPLEERNQDCQGLMEKFQFDLTLEEEDSDGPEKESDSIHYYGSTKTLCVIDPGKRDSQQDAN
IEIVTKDASPIDT
>gi|602696195|ref|XP_007460149.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4B [Lipotes vexillifer]
MKKSRSVMTVTADDNVKDYFECNLSKSYSSSSNTLGIDLWRGRRCCSGSLQLPPLSQRQSGRARTPEGDGISRPTTLPLM
TLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQH
GDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTPNKRSPAASQPSVSRVNLPEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFRQLLNRKIGYVSKECXMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHS
SSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLED
HYHADVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLEN
HHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLR
NMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPD
AQDILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHNYFSNTKTLCVIDPENRD
SLGETDVDITTEDKSPIDT
>gi|634857348|ref|XP_007942339.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Orycteropus afer afer]
MDTEGSSAPAPGSGEGGDSAGEATLKAPKHLWRHEQQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQPQCPLQPPPPPP
PLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGT
SAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNN
FAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHL
SEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELE
DVNKWGLHVFRIAELSGNRPLTVIMHTIFQVSWLSSVTFILFKDLISSLRIVHALCLLHXSNGNIICVVXFFQAVFTDLE
ILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVL
ATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERE
RGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQT
EKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGAEDESQPEACVLEDHSPDT
>gi|589953222|ref|XP_006989252.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like [Peromyscus maniculatus bairdii]
MQGPGGWSRTAALPPTPSAAPGASVSPTWQRPLPVRSRQRPHPRTDLDHRARAGEASRGAEPGPPLRPRLRPERLKGRDS
GAALARPAMQGPAAPGSPRGSPRGSPALFRKLPMSRSVRLQRRFTVAHAPWCPPPGLGMRGTADLCRAAAETAEWGRPPG
HRGTPSVSVLSVWAAVCERRVRGSRGAEPQLRALVGARTPVLHGEDMIVTPFAQVLASLRTVRSSVAALAHGTAPRRMGA
ARAPRRAPPXRPPPEAPGPQLAQETLEELDWCLEQLETLQTRRSVGEMASSKFRRMLSRELTHLSETSRSGIQVSEYIAQ
TFLGERXEVELPLLPAEDGDPAAPRVSLPAAAAVPRFGVHTDQEGQLAKELEDTNKWGLDVFRVAELSGSRPLTAVVFSV
LQERDLLQTFRIPADALRAYLLTLEGHYRADVAYHNSVHAADVVQSAHVLLGAPALQAVFTDLEVLAAVFACAIHDVDHP
GVSNQFLINTNSELALMYNDVSVLENHHLAVGFKLLQGENCDFFRNLSAKQRLSLRRMVIDMVLATDMSKHMSLLADLKT
MVETKRVTSLGVLLLDHYSDRIQVLQSLVHCADLSNPTKPLRLYRQWTERIMAEFFRQGDRERELGLDVSPMCDKHSASV
EKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNREWYQSRIPGSPTLTAGRERPGPDRFQFELTLEEAEEEDG
>gi|658867469|ref|XP_008416608.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Poecilia reticulata]
MIVTPFAQVLASLRTVRNNFGTLTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTN
SNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHAD
VAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAV
GFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHC
ADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDIL
DTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEENSCTDSKTL
CTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAANEEVAEDEEEEKSPDT
>gi|543715443|ref|XP_005498995.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Columba livia]
MKKSRSVMTVTADENALDYLECGLSKSYSTSSHTLGIDLWRGRRCCSGNLQLPPLSQRQTEKARTPDRDFVCRPTTLPLL
TPPSIAITSYQDCFDVENGPSPGRSPLDPQAGSSAGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQHG
DDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPAMSQPPVSRVNLQEEPYQKLAMETLEELDWCLDQLETIQTYRS
VSEMASNKVSRAAGRCEAEHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSL
NNTSISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYH
SDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMV
HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQD
ILDTLEDNRNWYQSMIPQSPSPPLEERGRDCQGLMEKFQFELTLEEEDSDGPEKDSESIGYFSNTKTLCVAEPGEEDSQR
EANIEIVTEDTSPVDT
>gi|436008|gb|AAA56857.1| phosphodiesterase, partial [Rattus norvegicus]
NSLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKR
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQ
EDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADV
VQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQL
YRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
TIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSYSDSKTLCTQDSESTEIPLDEQVEEEAVA
EEESQPQTGVADDCCPDT
>gi|471404884|ref|XP_004384445.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like [Trichechus manatus latirostris]
MASNKFKRMLNRELSHLSETSRSGNQVSKYISRTFLDQQTEVELPRVTPMETPQPMSQISSLRELPHSASLSAATVPRFG
VHTDQEGQLAKELEDTNKWGLDVFKVAELSRNRPLTAITFSIFQERDLLKTFRIPADTLVTYLLTLEGHYHADVAYHNSL
HAADVAQSTHVLLATPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDVSVLENHHLAVGFKLLQA
ENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVARLGVLLLDNYSDRIQVLQNLVHCADLSNPT
KPLPLYRQWTDRIMAEFFQQGDQERETGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNR
EWYQSKIPRSPPAPSSPQQGGPDRFQFELTLEEAEEEEEEEQVALDGEASELPDIELLSLKASPDPQIPQLASQRTVGKT
FVDYEGNMMAKPFGPRRWTSQE
>gi|542205060|ref|XP_005476150.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Oreochromis niloticus]
MRRSIGATVKHTEDMIVTPFAQVLASLRTVRSNFAVITGQQDRTASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELD
WCLEQLETLKTRHSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKQHDMDIMSPPTKEKDKKKRPMSQIS
GVKKATHSPSLAPSTIPRFGVNASQEGLLAKELEDINRWGIDIFKVSEYSGNRPLTVTMYTIFQERDLLKSFKIPVDTFI
TFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMY
NDLSVLENHHLAVGFKLLQEDNCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNY
SDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDREREKGMEISPMCDKHNASVEKNQVGFIDYIVHPLWET
WADLVHPDAQDILDTLEDNREWYQSMIPHSPSPHPEGQEEEEEEEDTFAGEASAHCRGSGSASADKFQFKLTLEEEGESD
TESPPEEEEGQSSSRRHEIYRSDSASPASRRLPKMLTSDSGRTFSLDSEKDMAEERETDEGVSGVPRFRIGT
>gi|554559064|ref|XP_005873930.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X7 [Myotis brandtii]
MAGHRTPQCQACLGLTGLVFRDACSMRRSGTALSFLLSEQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPP
GETEPSSCVVFTIGAQGTEQSHGPASSSFDLENALSRGRSAQDPQVGPGPGQVTQHSQRRESFLYRSESDYELLPKAMSR
NSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWC
LDQLETLQTRHSVGEMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGL
PHSASLSTATIPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLT
LEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASV
LENHHLAVGFKLLQAENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQ
QGDRERESGLDISPMCDKHTASVEKSQLGSH
>gi|558177221|ref|XP_006100427.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X8 [Myotis lucifugus]
MAGHRTPQCQACLGLTEPVFRDACSMRRSGTALSFLLSEQVRESVDSSSAPVSPRGSGVIWRRFSGTPLLPPLSSRLRPP
GETEPSSCVVFTIGARGTEQSHGPASSSFDLENALSRGRSAQDPQVGLGPGQVTQHSQRRESFLYRSESDYELLPKAMSR
NSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHLQGHRAAKQTSIGNPPSGSQPPPPPEDTGQKLALETLDELDWC
LDQLETLQTRHSVGDMASNKFKRMLTRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPKGTPKEPSRPMSQISGLQGL
PHSASLPTATTPCFGVQTDQEAQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQKRDLLKTFQIPVDTLATYLLT
LEGHYHADVAYHNSLHAADVAQSTHVLLAMPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASV
LENHHLAVGFKLLQAENCNVFQNLSTKEWLSLRRMVIDIVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQ
QGDRERESGLDISPMCDKHTASVEKSQLGSH
>gi|528922147|ref|XP_005196194.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X11 [Bos taurus] >gi|528998087|ref|XP_005221566.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X14 [Bos taurus]
MCNQPSINKATLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNT
FLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSG
NRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAI
FASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMS
KHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEI
SPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQF
ELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVADEESQPEACVIGDPSPDT
>gi|594655513|ref|XP_007176145.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X11 [Balaenoptera acutorostrata scammoni] >gi|594655515|ref|XP_007176146.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X12 [Balaenoptera acutorostrata scammoni]
MCNQPSINKATLTAEVIPEELKSRLEVISEEGGYPSLLTAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFK
RMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTE
QEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAAD
VVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCD
IFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQ
LYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ
STIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQAEEEAV
GEEEEESQPEACAIGAHSPDT
>gi|560908223|ref|XP_006180429.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Camelus ferus]
MAPFELACGPVKRLRTESPFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSR
SGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKW
GLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALE
AVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRK
MVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFR
QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPEDQE
EGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEENQPEAHVIED
HSPDT
>gi|281353903|gb|EFB29487.1| hypothetical protein PANDA_006807 [Ailuropoda melanoleuca]
EEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSP
TQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQ
ERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGV
SNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTE
KDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVGEEEESQPEACVVEDHSPDT
>gi|667256105|ref|XP_008565758.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Galeopterus variegatus]
MKEQPSCAGTGHPSMAGYGRMAPFELAGGPVKRLRTESPFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESQPEACAIDDDSPDT
>gi|586974833|ref|XP_006927803.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Felis catus]
MKEQPSCAGTGRPSMAGYGRMAPFELGGGPVKRLRTESPFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEETVGEEEDSQPEACVIEDHSPDT
>gi|591306575|ref|XP_007079979.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Panthera tigris altaica]
MKEQPSCAGTGRPSMAGYGRMAPFELVGGPVKRLRTEPPFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEETVGEEEDSQPEACVIEDHSPDT
>gi|26349173|dbj|BAC38226.1| unnamed protein product [Mus musculus] >gi|110277929|gb|ABG57272.1| cAMP-specific phosphodiesterase 4D isoform 1 [Mus musculus]
MKEQPSCAGTGHPSMAGYGRMAPFELAGGPVKRLRTESSFPCLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVAEEESQPETCVPDDCCPDT
>gi|432104613|gb|ELK31225.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Myotis davidii]
MAPFELAGSPVKRLRTEPPFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSR
SGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKW
GLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALE
AVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRK
MVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFR
QGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQE
EGRPGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEVPLDEQVEEEAVGDEEESQPEACVIDD
HSPDT
>gi|512918127|ref|XP_004903703.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Heterocephalus glaber]
MKEQPSCAGPGHSSMAGYGRMVPFELSGGPLKRLRTESPFSCLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGQQGQSEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESQPEVCVIDDCSPDT
>gi|512972895|ref|XP_004848550.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Heterocephalus glaber]
MKEQPSCAGPGHSSMAGYGRMVPFELSGGPLKRLRTESPFPCLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGQQGQSEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESQPEVCVIDDCSPDT
>gi|517502|gb|AAA20401.1| 3',5'-cyclic AMP phosphodiesterase [Rattus norvegicus] >gi|149059319|gb|EDM10326.1| rCG44727, isoform CRA_j [Rattus norvegicus] >gi|382335|prf||1819349A rolipram sensitive cAMP phosphodiesterase
MKEQPSCAGTGHPSMAGYGRMAPFELAGGPVKRLRTESPFPCLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVAEEESQPQTGVADDCCPDT
>gi|564267423|ref|XP_006272519.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Alligator mississippiensis]
MKEQRSCAGSGQRGAPVYGTMAPRPLAASPVKRLRTEYPFPYLLAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTDQEDGLAKELEDVNKWGLHVFRIAELSGNRPLTVVMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLHIYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
GEEVEEEESQTEPCVVEEDHSPDT
>gi|470644026|ref|XP_004326420.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 1 [Tursiops truncatus]
MKEQPSCAGTGHPSMTGYGRMAPFELAGGPVKRLRTECPFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQA
EEEAVGEEESQPEACAIGDHSPDT
>gi|593763887|ref|XP_007120536.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Physeter catodon]
MKEQPSCAGTGHPSMTGYGRMAPFELAGGPVKRLRTECPFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQDEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQA
EEEAVGEEEEESQPEACAIGDHSPDT
>gi|1236955|gb|AAA97890.1| cAMP-specific phosphodiesterase HPDE4D1 variant [Homo sapiens]
MKEQPSCAGTGHPSMAGYGRMAPFELASGPVKRLRTESPFPCLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLRTQDSESTEIPLDEQV
EEEAVGEEEESQPEACVIDDRSPDT
>gi|308387382|ref|NP_001184151.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D1 [Homo sapiens] >gi|119575386|gb|EAW54991.1| phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila), isoform CRA_j [Homo sapiens]
MKEQPSCAGTGHPSMAGYGRMAPFELASGPVKRLRTESPFPCLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVGEEEESQPEACVIDDRSPDT
>gi|499028288|ref|XP_004564871.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X9 [Maylandia zebra] >gi|554849366|ref|XP_005934974.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X9 [Haplochromis burtoni]
MSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEE
PYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPP
KEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQER
DLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTN
QFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVET
KKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQ
VSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQF
ELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQRA
PVSPGREGADTDRELSQEGDGVACLRLGT
>gi|548356307|ref|XP_005730281.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X10 [Pundamilia nyererei]
MSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEE
PYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPP
KEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQER
DLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIHDVDHPGVTN
QFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVET
KKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDKHNASIEKSQ
VSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSGGGGGDKFQF
ELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSSSSGRYRPPSPHPSRTLNLAAMSVRSPSPQR
APVSPGREGADTDRELSQEGDGVACLRLGT
>gi|3334455|gb|AAC26969.1| phosphodiesterase [Rattus norvegicus]
LRTESPFPCLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTF
LDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGN
RPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIF
ASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSK
HMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQEDRERERGMEIS
PMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFE
LTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPQTGVADDCCPDT
>gi|542231036|ref|XP_005454081.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Oreochromis niloticus]
MSRNSSTASDLEEGLKHWEVNWLPRHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPPMCNPCLTEE
PYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIANTFLEKQHDVEILSPPP
KEKEKKKRPMSQISGVKKATQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVTMYTIFQER
DLLKTFEIPVDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIIAALFASAIHDVDHPGVTN
QFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVET
KKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKEHFTQGDRERDRGMEISPMCDKHNASIEKTQ
VGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHHAEVGPAAVGAGAPIPSGGGGGDKFQF
ELTLEEEEEEDEEADSDLESPIEDQSQSAGERHRDSSPPSLAPDPRSSSGSRYRPPSPHPSRTLNLAAMSVRSPNPHRAL
ASPGREGVDRDRELSQEGDGVACLRLGT
>gi|556968476|ref|XP_005993213.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Latimeria chalumnae]
MCKTNLPEEACQKLAVETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEFISSTFLEKQH
EVEIPSPTAKEKEKKKRPMSQISGVKKLMHSSTLNHCTIPRFGVKTEKEGHLAKELEDISRWGLDIFKIAEYSGNRPLTV
MMYTIFQERDLLKTFRIPEDTFITYMMTLEDHYHTDVAYHNNIHAADVAQSTHVLLSTPALEAVFMDLEILAAIFASAIH
DVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLL
GDLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLDLYRQWTDRIMMEFFSQGDREREKGMEISPMCDK
HNASIEKSQVGFIDYVVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPQSPSPPPEEQDKEGNVGSDKFQFELTLEE
EGESDTEQETESPVEEDNSGCELQTPAMDDSESAEAQGSFERTEELSPTKLRGSVTDHSLGKSPVPGCNSATQTTLTDLQ
DHTNVDNRKATPRTLSRTESSTTEVQVAPGKEGSLKDKEASLDQEGNVTFLPLGT
>gi|528487512|ref|XP_695374.5| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Danio rerio]
MAQQAAVGHQDTLAVPPMPKHVGLNEDLVKILRENLLQQERPRGHRRSPSSISPRLSPRNSPRLLRRMLLNNNIHKQRRF
TVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPF
AQVLASLRTVRNNFAALTNVQQERSNNKRSPMCNPPPITKTSYTASLFLLVSSVMQAELLIRWSSGQVLAGALSVSLSLS
PACSGTGRLQASVSRGSSAHVRLATLFGCPALVQGIHLSENGGRADASTSVVFFAAGAETDTSPSSVGCSPASPTAGRLV
RITPLLFLETLCFGSIWSPIIHCGGLQHSMKNHPCVLSGYPNMAVYSSLGPLLGASARPLQQLRSDRLPPSLPPEEAYQK
LATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQNEVEMPSPQSQKDK
EKKKRPMSQISGVKKLTHSSSLTNSNIPRFGVKTETEDELAKELEDVNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLL
KTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFL
INTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKV
TSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGF
IDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPALDTSSEGRRAAGQEKFQFELTLEEDGESDTEKDSG
SPPEEDEEEEEEEENSCSDSKTLCTQDSECTEIPLDEQVGDVPHEDEYEHEENREISEPCVLEEEEEEEEEEEEDTANT
>gi|642089376|emb|CDQ82630.1| unnamed protein product [Oncorhynchus mykiss]
MKSHPCVHSGHLSIAVCGEADPGPAACARPLKRPCTDPLPPCLVPPEEAYQKLATETLEELDWCLDQLETLQTRHSVGEM
ASNKFKRMLNRELSHLSEMSRSGNQVSEFISSTFLDKQHEVEMPTPQTQKEKEDKKNRPMSEISGVKKLQHSSSLTNSNI
PRFGVKSETEDELAKELEDVNKWGLNVFKVTQFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLMTLEDHYHGDVAY
HNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL
SNPTKPLQLYRQWTDRIMEEFFTQGDRERERGMEISPMCDKHNASVQKSQVGFIDYIVHPLWETWADLVHPDAQDILDTL
EDNREWYQSTIPQSPSPTLDEPEDGSRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEDEEEENSCSDSKTLCTQDSES
TEILLDEQVGEEEEEEVEGESSSSQPCVVEEEEEGEEGEEKGEEKPDDT
>gi|409815|gb|AAA18924.1| 3',5'-cyclic AMP phosphodiesterase [Rattus norvegicus]
MKEQPSCAGTGHPSMAGYGRMAPFELAGGPVKRLRTESPFPCLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIF
QNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLY
RQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQST
IPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAE
EESQPQTGVADDCCPDT
>gi|525025614|ref|XP_005060264.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Ficedula albicollis]
MESFPAGLPGPGSPRGSPRNSPVFFRKLLMNQSIRLQRRFTVAHPLCFDLENGPPGRGALDPQASPGAGLVLQGTFSHGQ
RRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTIRSNLTHLQDRAGIKRGSSSSLPSGSKASLS
GECQGTAQGDFGTSWVSPCPQGVSCRALGGAAITPQSQGRAAALPFGIHVWFSAAPPAWPPFAAVEKLPLTSNLPLIKPR
RPCRVAALLAGPLPSWPVPPAEDAHQKLSRETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELSHLSETSRSGNQ
VSEYISSTFLDKQHEVEIPSALTKDKEKERRKRPMSQISGVRKLTHSSRLAAAGIPRFGVRTEHEALLAKELEDTNKWGL
DVFKVAEYSGNRPLTAIMYSIFQERDLMKTFRIPVNTFITYMLTLEDHYHADVAYHNNLHAADVAQSTHVLLSTPALEAV
FTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSRKQRQTLRKMV
IDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQG
DREREKGMEISPMCDKHTASVEKSQVGFIDFIAHPLWETWADLVHPDAQELLDTLEDNREWYQSMIPRSPSPPPEAPAAS
PANTDKFQFELTLEEEEEEGESDTELEGAESPLDEDNSGSKTPGTDDSECADTKRLSPGPGDRDSPVPRPSDVDNRRALE
GTLPKDGGSGCSAPGPEGTQGLCLDTEGNVTFLSLGT
>gi|284055548|pdb|3G4G|A Chain A, Crystal Structure Of Human Phosphodiesterase 4d With Regulatory Domain And D155871 >gi|284055549|pdb|3G4G|B Chain B, Crystal Structure Of Human Phosphodiesterase 4d With Regulatory Domain And D155871 >gi|284055550|pdb|3G4G|C Chain C, Crystal Structure Of Human Phosphodiesterase 4d With Regulatory Domain And D155871 >gi|284055551|pdb|3G4G|D Chain D, Crystal Structure Of Human Phosphodiesterase 4d With Regulatory Domain And D155871
MSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPKVTAEEAPQPMSQISGVKKLMHSSSLTNSS
IPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNREWYQSTIPQAHHHHHH
>gi|507615292|ref|XP_004623133.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Octodon degus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDPEEGPQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGGGESQPEVCVTDECSPDT
>gi|585679899|ref|XP_006891582.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Elephantulus edwardii]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEDAVGEAEESQPEVCIIEDHSPDT
>gi|594082622|ref|XP_006064906.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Bubalus bubalis] >gi|594082624|ref|XP_006064907.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Bubalus bubalis]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QGEEEAVADDEESQPEACVIGDPSPDT
>gi|670997471|ref|XP_008689616.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Ursus maritimus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEETVGEEEESQPEACVVEDHSPDT
>gi|507649559|ref|XP_004703652.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X6 [Echinops telfairi]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDPEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEITLDE
QVEEEAVGEETESQAEACVDEHSPDT
>gi|586541932|ref|XP_006906107.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Pteropus alecto]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDD
QVEEEAVGEEESQPEACVIDDCSPDT
>gi|545199156|ref|XP_005604256.1| PREDICTED: phosphodiesterase 4D, cAMP-specific isoform X7 [Equus caballus] >gi|664711489|ref|XP_008512720.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Equus przewalskii]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEESQPEACAAEDRSPDT
>gi|358417748|ref|XP_003583737.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Bos taurus] >gi|359077397|ref|XP_003587565.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX9 [Bos taurus] >gi|528922151|ref|XP_005196195.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X12 [Bos taurus] >gi|528998091|ref|XP_005221567.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X15 [Bos taurus] >gi|555953896|ref|XP_005889117.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Bos mutus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVADEESQPEACVIGDPSPDT
>gi|410948631|ref|XP_003981034.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Felis catus] >gi|591306577|ref|XP_007079980.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Panthera tigris altaica]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEETVGEEEDSQPEACVIEDHSPDT
>gi|504142690|ref|XP_004583781.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Ochotona princeps]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDPEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QAEEEAVAEEESQPEACVIDDCSPDT
>gi|556740082|ref|XP_005965589.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Pantholops hodgsonii]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQDSEATETPLDE
QVEEEAVAGGEGAQPEACVAGEPSPGT
>gi|612003360|ref|XP_007486427.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Monodelphis domestica]
MASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSPVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEEEEDPAEPCAIENEHSPDT
>gi|507934238|ref|XP_004678352.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Condylura cristata]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGHTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEESQPEACVIEDRSPDT
>gi|655839253|ref|XP_008260475.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Oryctolagus cuniculus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEESQPEACVIDDYSPDT
>gi|641695233|ref|XP_008160066.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Eptesicus fuscus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEEVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEESQPEACVIDDHSPDT
>gi|533157535|ref|XP_005392727.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Chinchilla lanigera]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGQQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEESQPEVCVVDDCSPDT
>gi|488534372|ref|XP_004458899.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 12 [Dasypus novemcinctus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQERELLKTFKIPVDTLITYLMTLEDHYHADVAYH
NYIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEESQPEACVIEDHSPDT
>gi|640802674|ref|XP_008057672.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Tarsius syrichta]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEESQPETCIIDDRSPDT
>gi|584085534|ref|XP_006762505.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Myotis davidii]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRPGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEVPLDE
QVEEEAVGDEEESQPEACVIDDHSPDT
>gi|594655517|ref|XP_007176147.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X13 [Balaenoptera acutorostrata scammoni]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QAEEEAVGEEEEESQPEACAIGAHSPDT
>gi|505801958|ref|XP_004608517.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Sorex araneus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPTPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDPEEGRQGQTDKFQFELTLEEDGESDTEKDCGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEECQPEASVVEDHSPDT
>gi|602680959|ref|XP_007453283.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Lipotes vexillifer]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QAEEEAVGEEERQPEACAIGDHSPDT
>gi|617572970|ref|XP_007516967.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Erinaceus europaeus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEAEGEEEECQPETCVVEEDHCPDT
>gi|466035425|ref|XP_004275226.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 8 [Orcinus orca] >gi|470644032|ref|XP_004326422.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 3 [Tursiops truncatus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QAEEEAVGEEESQPEACAIGDHSPDT
>gi|589937927|ref|XP_006981719.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Peromyscus maniculatus bairdii]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVAEEEASQPETCVADDCCPDT
>gi|672041404|ref|XP_008758945.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Rattus norvegicus] >gi|517417|gb|AAA20393.1| 3',5'-cyclic AMP phosphodiesterase [Rattus norvegicus] >gi|149059318|gb|EDM10325.1| rCG44727, isoform CRA_i [Rattus norvegicus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVAEEESQPQTGVADDCCPDT
>gi|593763889|ref|XP_007120537.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Physeter catodon]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQDEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QAEEEAVGEEEEESQPEACAIGDHSPDT
>gi|524922720|ref|XP_005065614.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Mesocricetus auratus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVAEEEGNQPETCVIEDCCPDT
>gi|478497141|ref|XP_004422909.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 9 [Ceratotherium simum simum]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQSMVHCADLS
NPTKPLQLYRQWTDRVMEEFFRQGDRERERGMEISPMCDKHSASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEESQPEACAIEDPSPDT
>gi|568984467|ref|XP_006517712.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Mus musculus] >gi|110277931|gb|ABG57273.1| cAMP-specific phosphodiesterase 4D isoform 2 variant 1 [Mus musculus] >gi|110277933|gb|ABG57274.1| cAMP-specific phosphodiesterase 4D isoform 2 variant 2 [Mus musculus] >gi|110277935|gb|ABG57275.1| cAMP-specific phosphodiesterase 4D isoform 2 variant 3 [Mus musculus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVAEEESQPETCVPDDCCPDT
>gi|344235948|gb|EGV92051.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Cricetulus griseus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVAEEEGNQPETCVIDDCCPDT
>gi|635028364|ref|XP_007971577.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X10 [Chlorocebus sabaeus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEESQSEACVIDDRSPDT
>gi|345794114|ref|XP_003433855.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX6 [Canis lupus familiaris]
MASSSFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEETVGEEENSQPEACVIEDHSPDT
>gi|1236957|gb|AAA97891.1| cAMP-specific phosphodiesterase HPDE4D2 variant [Homo sapiens]
MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLRTQDSESTEIPLDE
QVEEEAVGEEEESQPEACVIDDRSPDT
>gi|308387378|ref|NP_001184150.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D2 [Homo sapiens] >gi|332233637|ref|XP_003266010.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 6 [Nomascus leucogenys] >gi|426384634|ref|XP_004058864.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 5 [Gorilla gorilla gorilla] >gi|530379376|ref|XP_005248598.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Homo sapiens] >gi|544437315|ref|XP_005557021.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X12 [Macaca fascicularis] >gi|2735859|gb|AAC00070.1| cAMP-specific phosphodiesterase PDE4D2 [Homo sapiens] >gi|119575379|gb|EAW54984.1| phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila), isoform CRA_c [Homo sapiens]
MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEESQPEACVIDDRSPDT
>gi|449279548|gb|EMC87120.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D, partial [Columba livia]
PPAEDAQQKLSRETLEELDWCLEQLETLRTRHSVSEMASNKVRNPGMDPTSPCWGAETPRMGNWGRSGNQVSEYISSTFL
DKQQEVEIPPAKDKDKEKERRKRPMSQISGVRKLPHGSSLAAAAIPRFGVRTDQEGLLAKELEDTNKWGLNVFKVAEYSG
NRPLTVIMYSIFQERDLMKTFRIPVDTFITYMLTLEDHYHADVAYHNSIHAADVAQSTHVLLSTPALEAVFTDLEIMAAI
FASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMAIDMVLATDMS
KHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEI
SPMCDKLTASVEKSQVGFIDFIAHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPPPEGPGVSPAATDKFQFE
LTLEEEEEEGELDTEPEGAESPL
>gi|472378768|ref|XP_004408802.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 9 [Odobenus rosmarus divergens]
MASSSFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEETVGEEEDSQPAACVIEDHSPDT
>gi|543263219|ref|XP_005422034.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Geospiza fortis]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQ
DSESTEIPLDEQVGEEVEEDENQTAEPCVVEEHSPDT
>gi|488534374|ref|XP_004458900.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 13 [Dasypus novemcinctus]
MASSSFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQERELLKTFKIPVDTLITYLMTLEDHYHADVAYH
NYIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEESQPEACVIEDHSPDT
>gi|586491558|ref|XP_006876234.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X8 [Chrysochloris asiatica]
MANSSFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEESQPEACVIEDHSPDT
>gi|511840339|ref|XP_004744674.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X13 [Mustela putorius furo] >gi|511942084|ref|XP_004789816.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X13 [Mustela putorius furo]
MASSSFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEETVGEEEDSQPEPCGIEDHSPDT
>gi|542162320|ref|XP_005489827.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Zonotrichia albicollis]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQ
DSESTEIPLDEQVGEEVEEEENQTAESCVVEEHSPDT
>gi|669263972|ref|XP_008641158.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Corvus brachyrhynchos]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQ
DSESTEIPLDEQVGEEVEEEENQTAEPCVVEEHSPDT
>gi|525026535|ref|XP_005060713.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Ficedula albicollis]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEEGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQ
DSESTEIPLDEQVGEEVEEEENQTAEPCMVEEHSPDT
>gi|584029022|ref|XP_006809034.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X1 [Neolamprologus brichardi]
MCNPCLTEEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQH
DVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTV
TMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPALEVVFTDLEIIAALFASAIH
DVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFL
ADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISPMCDK
HNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPEEHQAEVGPAALGAGAPIPSG
GGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSGRYRPPSPHPSRTLNLAAMSVR
SPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|532027748|ref|XP_005356841.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Microtus ochrogaster]
MSSFKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLE
DNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVAEEEASQPETCAIDDGCPDT
>gi|513229269|ref|XP_004937316.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Gallus gallus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTVFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVGEEVEEEENQTESCVVDHSPDT
>gi|543382248|ref|XP_005534314.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Pseudopodoces humilis]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTDQEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPRSPSPAPEEKEVGKQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDASFSDSKTLCTQ
DSESTEIPLDEQVGEVEEEVNQAAEPCVVEEHSPDT
>gi|507615290|ref|XP_004623132.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Octodon degus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGPQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGGGESQPEVCVTDECSPDT
>gi|586491556|ref|XP_006876233.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X7 [Chrysochloris asiatica]
MPEVNYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEACVIEDHSPDT
>gi|591357848|ref|XP_007053944.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Chelonia mydas]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVIMHTIFQERDLLKTFKIPADTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQ
DSESTEIPLDEQVGEEVEGEESHTEPCVLEEDHSPDT
>gi|504142688|ref|XP_004583780.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Ochotona princeps]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQAEEEAVAEEESQPEACVIDDCSPDT
>gi|527267755|ref|XP_005151991.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Melopsittacus undulatus]
MSQNEFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPAQKEKEKKKRPMSQISGVKKLMHSTSLTNSSIP
RFGVKTEHEESLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHSDVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLSKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLDLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVHPLWETWADLVHPDAQEILDTLE
DNREWYQSTIPQSPSPAADDQEESKQTQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
PVGEEVEEEENQTEPCVVEGHTPNT
>gi|358417744|ref|XP_003583735.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Bos taurus] >gi|359077391|ref|XP_003587563.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX7 [Bos taurus] >gi|555953894|ref|XP_005889116.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Bos mutus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVADEESQPEACVIGDPSPDT
>gi|594082620|ref|XP_006064905.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Bubalus bubalis]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQGEEEAVADDEESQPEACVIGDPSPDT
>gi|545199154|ref|XP_005604255.1| PREDICTED: phosphodiesterase 4D, cAMP-specific isoform X6 [Equus caballus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEACAAEDRSPDT
>gi|585679896|ref|XP_006891581.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Elephantulus edwardii]
MPEVNYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEDAVGEAEESQPEVCIIEDHSPDT
>gi|471392361|ref|XP_004380556.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 7 [Trichechus manatus latirostris]
MPEVNYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEERQPEACVIEDHSPDDT
>gi|585151190|ref|XP_006728033.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Leptonychotes weddellii]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEETVGEEEDSQPEACVIEDHSPDT
>gi|512918131|ref|XP_004903704.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Heterocephalus glaber] >gi|512972897|ref|XP_004848551.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Heterocephalus glaber]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGQQGQSEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEVCVIDDCSPDT
>gi|507649555|ref|XP_004703651.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Echinops telfairi]
MPEVNYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEITLDEQVEEEAVGEETESQAEACVDEHSPDT
>gi|345794116|ref|XP_003433856.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoformX7 [Canis lupus familiaris]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEETVGEEENSQPEACVIEDHSPDT
>gi|514461576|ref|XP_005003828.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Cavia porcellus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDEQEEGQQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEESQPEVCVIDDCSPDT
>gi|472378766|ref|XP_004408801.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 8 [Odobenus rosmarus divergens]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEETVGEEEDSQPAACVIEDHSPDT
>gi|667256108|ref|XP_008565759.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Galeopterus variegatus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEACAIDDDSPDT
>gi|533157533|ref|XP_005392726.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Chinchilla lanigera]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGQQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEESQPEVCVVDDCSPDT
>gi|426246457|ref|XP_004017010.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 6 [Ovis aries]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQ
DSEATRGAREEAREAGGGAQPEACVAGEPSPGT
>gi|335303949|ref|XP_003359834.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 8 [Sus scrofa]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEACGIEDPSPDT
>gi|507934236|ref|XP_004678351.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Condylura cristata]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGHTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEESQPEACVIEDRSPDT
>gi|470644029|ref|XP_004326421.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 2 [Tursiops truncatus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQAEEEAVGEEESQPEACAIGDHSPDT
>gi|612003358|ref|XP_007486426.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Monodelphis domestica]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTDQEDGLAKELEDVNKWGLHVFKIAEFSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSPVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEEEEDPAEPCAIENEHSPDT
>gi|560908221|ref|XP_006180428.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Camelus ferus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPEDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEENQPEAHVIEDHSPDT
>gi|505801954|ref|XP_004608516.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Sorex araneus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPTPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTDKFQFELTLEEDGESDTEKDCGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEECQPEASVVEDHSPDT
>gi|602680957|ref|XP_007453282.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Lipotes vexillifer]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQAEEEAVGEEERQPEACAIGDHSPDT
>gi|556740080|ref|XP_005965588.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Pantholops hodgsonii]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQ
DSEATETPLDEQVEEEAVAGGEGAQPEACVAGEPSPGT
>gi|554526276|ref|XP_005857980.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [Myotis brandtii]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEVPLDEQVEEEAVGDEEESQPEACVIDDHSPDT
>gi|617572965|ref|XP_007516966.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Erinaceus europaeus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEAEGEEEECQPETCVVEEDHCPDT
>gi|641695231|ref|XP_008160065.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Eptesicus fuscus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEEVNKWGLHVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLVTYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEACVIDDHSPDT
>gi|532027746|ref|XP_005356840.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Microtus ochrogaster]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVAEEEASQPETCAIDDGCPDT
>gi|466035420|ref|XP_004275225.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 7 [Orcinus orca]
MPEANYLRSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQAEEEAVGEEESQPEACAIGDHSPDT
>gi|488534370|ref|XP_004458898.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 11 [Dasypus novemcinctus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDILAKELEDVNKWGLHVFRIAELSGNRPLTVIMYTIFQERELLKTFKIPVDTLITYLMTL
EDHYHADVAYHNYIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLNKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEESQPEACVIEDHSPDT
>gi|110277939|gb|ABG57277.1| cAMP-specific phosphodiesterase 4D isoform 10 [Mus musculus]
MSKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRF
GVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQ
EENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNP
TKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDN
REWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQV
EEEAVAEEESQPETCVPDDCCPDT
>gi|511840337|ref|XP_004744673.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X12 [Mustela putorius furo] >gi|511942082|ref|XP_004789815.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X12 [Mustela putorius furo]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEETVGEEEDSQPEPCGIEDHSPDT
>gi|672041402|ref|XP_008758944.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [Rattus norvegicus] >gi|22901880|gb|AAN10116.1| cAMP-specific phosphodiesterase PDE4D6 [Rattus norvegicus] >gi|149059320|gb|EDM10327.1| rCG44727, isoform CRA_k [Rattus norvegicus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVAEEESQPQTGVADDCCPDT
>gi|524922718|ref|XP_005065613.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Mesocricetus auratus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVAEEEGNQPETCVIEDCCPDT
>gi|568984465|ref|XP_006517711.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X6 [Mus musculus] >gi|110277937|gb|ABG57276.1| cAMP-specific phosphodiesterase 4D isoform 6 [Mus musculus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVAEEESQPETCVPDDCCPDT
>gi|530639748|ref|XP_005306658.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Chrysemys picta bellii]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVVMNTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQ
DSESTEIPLDEQVGEEVEGEESHPEPCVLEEDHSPDT
>gi|478497139|ref|XP_004422908.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 8 [Ceratotherium simum simum]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQSMVHCADLSNPTKPLQLYRQWTDRVMEEFFRQGDRERERGMEISPMCDKHSASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEACAIEDPSPDT
>gi|637259367|ref|XP_008101086.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X7 [Anolis carolinensis]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPKFGVKTDQEDILAKELEDVNKWGLQVFKIAEFSGNRPLTVIMYTIFQERELLKTFKIQPDMLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTDKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVGGEVEEEEEEEQSQTEHCVQEEHSPDT
>gi|635028362|ref|XP_007971567.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X9 [Chlorocebus sabaeus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQSEACVIDDRSPDT
>gi|548511766|ref|XP_005694736.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Capra hircus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDCQTLCTQ
DSEATRGGGGGGGGGGGGGPSRRPASPGSPPRARNGAQTPMPFVCVFCFFK
>gi|308387384|ref|NP_001184152.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D6 [Homo sapiens] >gi|332233635|ref|XP_003266009.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 5 [Nomascus leucogenys] >gi|426384632|ref|XP_004058863.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform 4 [Gorilla gorilla gorilla] >gi|544437313|ref|XP_005557020.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X11 [Macaca fascicularis] >gi|22901882|gb|AAN10117.1| cAMP-specific phosphodiesterase PDE4D6 [Homo sapiens] >gi|119575387|gb|EAW54992.1| phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila), isoform CRA_k [Homo sapiens]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|527267753|ref|XP_005151990.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3 [Melopsittacus undulatus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPAQKEKEKKKRPMSQISGVKKLM
HSTSLTNSSIPRFGVKTEHEESLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHSDVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLDLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKTQVGFIDYIVHPLWETWADLVH
PDAQEILDTLEDNREWYQSTIPQSPSPAADDQEESKQTQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEPVGEEVEEEENQTEPCVVEGHTPNT
>gi|402871613|ref|XP_003899750.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D, partial [Papio anubis]
FKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVK
TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEEN
CDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
YQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEE
AVGEEEESQPEACVIDDRSPDT
>gi|514740617|ref|XP_005018307.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Anas platyrhynchos]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLHLYRXXXXXXXRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLW
ETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCS
DSKTLCTQDSESTEIPLDEQVGEEVEEEENQTEPCVVEDHAPDT
>gi|562877030|ref|XP_006166283.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Tupaia chinensis]
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQ
EDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADV
VQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQL
YRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
TIPQSPSPAPDDQEEGRQGQPEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEETVG
EEEESQPEACVVEDHSPDT
>gi|23274169|gb|AAH36319.1| PDE4D protein [Homo sapiens] >gi|325463277|gb|ADZ15409.1| phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) [synthetic construct] >gi|649120376|gb|AIC54879.1| PDE4D, partial [synthetic construct]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVFNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|543729061|ref|XP_005505604.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Columba livia]
MMKKDALGMALPEQVAAALKAPGATTSGEAAGLLGSAELGLLKLASPELERLIIQSNGLVTTTPTSGQFLYPKAAASEEQ
EFAEGFVKALEDLTWADKGTAVLALPSNRCRVPRGHSGVPIAGRRGAACHHIDSRSTYIFTQPSHSITSHHNARLSSTYN
TPNQHDGSTVIVPANRSPAPSSPAPSSAPSSPAPSSAPSSPAPSSPAPTGTPSANTLSTSSRTTAAISTGTAAGSSAQPP
AKPSPGVVVIICLFVCVLVGAAAVLLPLGWATLPTAYHSPGASPAVSPCSSPRNSPRNSPVLFRKLLMNQSIRLQRRFTV
AHPLCFDLEHGPPGRGALDPQASPGLVLQGTFPHGQRRESFLYRSDSDYPVSPPAEDAQQKLSRETLEELDWCLEQLETL
RTRHSVSEMASNKVRNPGMDPTSRSGNQVSEYISSTFLDKQQEVEIPPAKDKDKEKERRKRPMSQISGVRKLPHGSSLAA
AAIPRFGVRTDQEGLLAKELEDTNKWGLNVFKVAEYSGNRPLTVIMYSIFQERDLMKTFRIPVDTFITYMLTLEDHYHAD
VAYHNSIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAV
GFKLLQEENCDIFQNLSKKQRQSLRKMAIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHC
ADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEISPMCDKLTASVEKSQVGFIDFIAHPLWETWADLVHPDAQEIL
DTLEDNREWYQSMIPRSPSPPPEGPGVSPAATDKFQFELTLEEEEEEGELDTEPEGAESPLDEDNSGSKTPATDDSDVDN
RRALEGTLPKDGGSGCSVPGAEGSQGLCLDTEGNVTFLSLGRATEDAGVRAGHDAHLRPPPQLRGALGASSPTAGPGAPG
KL
>gi|641775076|ref|XP_008171008.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Chrysemys picta bellii]
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTEQ
EDVLAKELEDVNKWGLHVFKIAELSGNRPLTVVMNTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADV
VQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQL
YRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
TIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSFSDSKTLCTQDSESTEIPLDEQVGEEVEG
EESHPEPCVLEEDHSPDT
>gi|589937929|ref|XP_006981720.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X5 [Peromyscus maniculatus bairdii]
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQ
EDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADV
VQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQL
YRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
TIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVA
EEEASQPETCVADDCCPDT
>gi|542225993|ref|XP_005452175.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X12 [Oreochromis niloticus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKL
QHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMT
LEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEEN
SCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEVVEEGETPCSQSCVVEEEVAEEEEEEEEEEKAKSPDT
>gi|551486745|ref|XP_005794952.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X4 [Xiphophorus maculatus]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKL
QHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMT
LEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEENSCT
DSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGDAEEEGETPCSEPCVADEEVAEDEEEKKSPDT
>gi|658867471|ref|XP_008416609.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8 [Poecilia reticulata]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKL
QHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMT
LEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEEN
SCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAANEEVAEDEEEEKSPDT
>gi|657815922|ref|XP_008335090.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X5 [Cynoglossus semilaevis]
MPEANYLLSVSWEYIKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVELPSPHMQKEKEKKNKPMSQISGVKKL
QHSSSLSNSNIPRFGVKTETENELAKELEHVNKWGLNVFKISEFSGNQPLTVMMYTIFQERDLLKTFKIPLDTFITYLMT
LEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYCQWTDRIMEEFYSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDSTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEDEEEEDNSCT
DSKTLCTQDSESTEIPLDEQVVEEEEEVAKNQEEVPCLQPCVLEDVAEVEDNKKSSDT
>gi|617386814|ref|XP_007548212.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X7 [Poecilia formosa]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKL
QHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNLFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMT
LEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEDNREWYQSTIPQSPSPALDEPEDGTRPPGADKFQFELTLEEDGESDTEKDSGSQPEEEEEEEEEEEEE
NSCTDSKTLCTQDSESTEIPLDEQVGEDDDDDDEEGNAEEEGETPCSEPCAADEEVAEDEKEGKSPDT
>gi|409816|gb|AAA18925.1| 3',5'-cyclic AMP phosphodiesterase [Rattus norvegicus]
MASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIP
RFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCD
IFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQ
LYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ
STIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAV
AEEESQPQTGVADDCCPDT
>gi|114600137|ref|XP_517751.2| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform 9 [Pan troglodytes]
MPEANYLLSVSWGYIKFETKLSRXLTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLM
HSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTL
EDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVH
PDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQ
DSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
>gi|597802632|ref|XP_007242630.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [Astyanax mexicanus]
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPQTQKDKEKKKRPMSQISGVKKLTHSSSLSNSNIPRFGVKTD
TEDLLAKELEDVNKWGLNVFKVTEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHGDVAYHNNIHAAD
VTQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCD
IFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQ
LYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ
STIPQSPSPALDTSTEGRRTAGQDKFQFELTLEEDGESDTEKDSGSPADEEEEEEEEEEEEEEENSCSDSKTLCTQDSES
TEIPLDEPAEGEEVGEEPREEKEGHISEPCVLEEEEEEEEEEDEEDEEVEEEDEQNTANT
>gi|663283292|ref|XP_008499217.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Calypte anna]
MASNKFKRMLSRELTHLSETSRSGNQVSEYISSTFLDKQHEVELPSALAKEKEKERRKRPMSQISGVRKLMHSSNLTATT
IPRFGVRTDQEELLAKELEDTNKWGLDIFKVAEYSGNRPLTVIMYSIFQERDLMKTFHIPVDTFITYMLTLEDHYHIDVA
YHNNIHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGF
KLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCSD
LSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEISPMCDKHTASVEKSQVGFIDFIAHPLWEAWADLVHPDAQAILDT
LEDNREWYQSMIPRSPSPPPEEPGVSPATADKFQFELTLDEEEEDEEEEEGESDTELEETESPLDEDNSGCKTPDSESVD
TEHLSPGPGDQDSPVTRPRDMDNRQVLEGTLLQDGGGSGRSVSGPEDNQGLCLDTEGNVTFLSLDT
>gi|483514694|gb|EOB02211.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D, partial [Anas platyrhynchos]
QFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGV
KTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIMHTIFQANLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEEN
CDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LHLYRXXXXXXXRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILD
TLEDNREWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIP
LDEQVGEEVEEEENQTEPCVVEDHAPDT
>gi|632949777|ref|XP_007890349.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X3 [Callorhinchus milii]
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHECEMPSPSQKDKDKKKRPMSQISGVKKLT
HSSSLTNSSIARFGVKTDQEELLSKELEKVNKWGLNIFKVAEHSGNRPLTVVMYTIFQERDLLKTFKIPVDTLLTYLMTL
EDHYHADVAFHNNIHAADVAQSTHVLLSTPALEAVFTDLEVLTAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVL
ENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDENNASIEKTQVGFIDYIVHPLWETWADLVH
PDAQDMLDTLEDNREWYQSTIPQSPSPAPDEDEEGRPGQVDKFQFELTLEEDCESDTEKDSGASQGEDDNSCSDSKTLCT
QNSESTEIQLDDQGDEEEDDDDAPIEICAVEEEEEAADT
>gi|667339187|ref|XP_008561769.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Galeopterus variegatus]
MASNKFKRMLNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPRATPEEPPRPMSQISGLRGLPHSASLSSATVPRFG
VQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDASVLENHHLAVGFKLLQGENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVASLGVL
LLDNYSDRIQVLQNLVHCADLSNPTKPLSLYRQWTDRIMAEFFQQGDRERDSGLDVSPMCDKHTASVEKSQVGFIDYIAH
PLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDPTSPERGGPDRFQFELTLEEAEEEEESVLDRVALESPDPDPG
ALPVDNQRT
>gi|527244095|ref|XP_005140395.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like, partial [Melopsittacus undulatus]
FKRMLSRELTQLSETSRSGNQVSEYISSTFLDKQHEVEIPSAPAKDKEKERRNRPMSQISGVRKLTHGSSLAAAGIPRFG
VRTEHEALLAKELEDTNKWGLNVFKVAEYSGNHPLTVIMYSIFQERDLMKTFRIPVDTFITYMLTLEDHYHADVAYHNSI
HAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDTSVLENHHLAVGFKLLQE
ENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPT
KPLELYRQWTDRIMGEFFRQGDQEREKGMEISPMCDKHTASVEKSQVGFIDFIAHPLWETWADLVHPDAQELLDTLEDNR
EWYHSMIPRSPSPPPPAGHGASPAGTDRFQFELTLEEEEEEEEEGELDTEPEGAESPLDEDNSGSKTPATDDSGSADIKC
LSPGPGDRDSPVPCPRDVDNRQALEGTMPKDSDGNGRSGTGPEGLCLDTEGNVTFLPLGT
>gi|669290368|ref|XP_008638183.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Corvus brachyrhynchos]
MLPTTHCSPGASPAASPRSSPRNSPVLFRKLLMNQSIRLQRRFTVAHPLCFDLENGPPGRGALDPQASPGAGLVLQGTFS
HGQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVGANAVPCPGGDAARTQHRVSEYISSTFLDKQHEV
EIPSALAKDKEKERRKRPMSQISGVRKLTHSSSLAAAGIPRFGVRTDHEALLAKELEDTNKWGLNVFKVAEYSGNRPLTV
IMYSIFQERDLMKTFRIPVNTFITYMLTLEDHYHADVAYHNNLHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIH
DVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSRKQRQTLRKMVIDMVLATDMSKHMNLL
ADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQGDREREKGMEISPMCDK
HTASVEKSQVGFIDFIAHPLWETWADLVHPDAQELLDTLEDNREWYQSMIPRSPSPPPEGATVSPATTDKFQFELTLEEE
EEGESDTELEGTESPLDEDNSGSKTPGTDDSESADTKRLSPGAGDRDSPVPRPRARSTPRGDAAEGRWQRVLRA
>gi|565312985|gb|ETE65433.1| cAMP-specific 3',5'-cyclic phosphodiesterase 4D, partial [Ophiophagus hannah]
MRSLTHRELISIIHIALFEDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTDQEDILAKELE
DVNKWGLQVFKIAELSGNRPLTVIMYTIFQERDLLKTFKIPPDMLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLS
TPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQK
QSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIM
EEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPA
PDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVGEEVVEEEEEENQSE
PCVLEERSPDT
>gi|206130|gb|AAA41847.1| cyclic nucleotide phosphodiesterase, partial [Rattus norvegicus]
PMAQITGLRKSCHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVLQERDLLKTFQIP
ADTLLRYLLTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVL
LLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAH
PLWETWADLVHPDAQELLDTLEDNREWYQSRVPCNPPHA
>gi|545808755|ref|XP_003480802.2| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C, partial [Sus scrofa]
EGKLAKELEDTNKWGLDVFKVAELSGNRPLTAITFNIFQERDLLKTFQIPADTLVTYLLTLEGHYHNDVAYHNSLHAADV
AQSTHVLLGTPALEAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQVENCDI
FQNLSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPTKPLPL
YRQWTDRIMAEFFQQGDRERDSGLDISPMCDKHTASVEKSQVGFIXLHRHPLWXTWLTCTPDAQTADTLEDXREWYQSKI
PHSPPVDPTSPKQGGPDRFQFHLTLEEAEEEEEEEAGALDGEVSQSADTELLSPEDSPDPGALPLDDQRTEGKPCVDHKG
NVIAETLGT
>gi|284055552|pdb|3G4I|A Chain A, Crystal Structure Of Human Phosphodiesterase 4d With D155871 >gi|284055553|pdb|3G4I|B Chain B, Crystal Structure Of Human Phosphodiesterase 4d With D155871 >gi|284055554|pdb|3G4I|C Chain C, Crystal Structure Of Human Phosphodiesterase 4d With D155871 >gi|284055555|pdb|3G4I|D Chain D, Crystal Structure Of Human Phosphodiesterase 4d With D155871 >gi|284055556|pdb|3G4K|A Chain A, Crystal Structure Of Human Phosphodiesterase 4d With Rolipram >gi|284055557|pdb|3G4K|B Chain B, Crystal Structure Of Human Phosphodiesterase 4d With Rolipram >gi|284055558|pdb|3G4K|C Chain C, Crystal Structure Of Human Phosphodiesterase 4d With Rolipram >gi|284055559|pdb|3G4K|D Chain D, Crystal Structure Of Human Phosphodiesterase 4d With Rolipram >gi|284055560|pdb|3G4L|A Chain A, Crystal Structure Of Human Phosphodiesterase 4d With Roflumilast >gi|284055561|pdb|3G4L|B Chain B, Crystal Structure Of Human Phosphodiesterase 4d With Roflumilast >gi|284055562|pdb|3G4L|C Chain C, Crystal Structure Of Human Phosphodiesterase 4d With Roflumilast >gi|284055563|pdb|3G4L|D Chain D, Crystal Structure Of Human Phosphodiesterase 4d With Roflumilast >gi|284055564|pdb|3G58|A Chain A, Crystal Structure Of Human Phosphodiesterase 4d With D155988PMNPQ >gi|284055565|pdb|3G58|B Chain B, Crystal Structure Of Human Phosphodiesterase 4d With D155988PMNPQ >gi|284055566|pdb|3G58|C Chain C, Crystal Structure Of Human Phosphodiesterase 4d With D155988PMNPQ >gi|284055567|pdb|3G58|D Chain D, Crystal Structure Of Human Phosphodiesterase 4d With D155988PMNPQ
MSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHAD
VAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAV
GFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHC
ADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDIL
DTLEDNREWYQSTIPQAPAPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGHHHHHH
>gi|93279640|pdb|2FM0|A Chain A, Crystal Structure Of Pde4d In Complex With L-869298 >gi|93279641|pdb|2FM0|B Chain B, Crystal Structure Of Pde4d In Complex With L-869298 >gi|93279642|pdb|2FM0|C Chain C, Crystal Structure Of Pde4d In Complex With L-869298 >gi|93279643|pdb|2FM0|D Chain D, Crystal Structure Of Pde4d In Complex With L-869298 >gi|93279644|pdb|2FM5|A Chain A, Crystal Structure Of Pde4d2 In Complex With Inhibitor L- 869299 >gi|93279645|pdb|2FM5|B Chain B, Crystal Structure Of Pde4d2 In Complex With Inhibitor L- 869299 >gi|93279646|pdb|2FM5|C Chain C, Crystal Structure Of Pde4d2 In Complex With Inhibitor L- 869299 >gi|93279647|pdb|2FM5|D Chain D, Crystal Structure Of Pde4d2 In Complex With Inhibitor L- 869299 >gi|354459605|pdb|3SL3|A Chain A, Crystal Structure Of The Apo Form Of The Catalytic Domain Of Pde4d2 >gi|354459606|pdb|3SL3|B Chain B, Crystal Structure Of The Apo Form Of The Catalytic Domain Of Pde4d2 >gi|354459607|pdb|3SL3|C Chain C, Crystal Structure Of The Apo Form Of The Catalytic Domain Of Pde4d2 >gi|354459608|pdb|3SL3|D Chain D, Crystal Structure Of The Apo Form Of The Catalytic Domain Of Pde4d2 >gi|354459609|pdb|3SL4|A Chain A, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 10d >gi|354459610|pdb|3SL4|B Chain B, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 10d >gi|354459611|pdb|3SL4|C Chain C, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 10d >gi|354459612|pdb|3SL4|D Chain D, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 10d >gi|354459617|pdb|3SL6|A Chain A, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 12c >gi|354459618|pdb|3SL6|B Chain B, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 12c >gi|354459619|pdb|3SL6|C Chain C, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 12c >gi|354459620|pdb|3SL6|D Chain D, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 12c >gi|354459621|pdb|3SL8|A Chain A, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 10o >gi|354459622|pdb|3SL8|B Chain B, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 10o >gi|354459623|pdb|3SL8|C Chain C, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 10o >gi|354459624|pdb|3SL8|D Chain D, Crystal Structure Of The Catalytic Domain Of Pde4d2 With Compound 10o
IPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLE
>gi|530564987|ref|XP_005279064.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X3 [Chrysemys picta bellii]
MPSPPWAAAPQSPLDLGVQRKALWGASHGRSAGGATGRPMGVSGQAPALEEKTRSPCRCAGAWPCWRGSSWRAQDRMSLP
TSCGSVALADCALMVCNGHLAGSPRAVNRPIDIAQKHRRFDIENGLSSGRSPLDPQASPGSGLVLQGNVPHSQRRESFLY
RSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVASKRTSSSNPPSVCKASLSEDAC
QKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDKQHEVEIPSPTPKE
KEAEKTTRPMAQISGLKKLTHSSSFISSSIPRFGVKTDQEGLLAKELKDTNKWGLDMFKITEYSGNRPLTVVMYSIFQER
DLMKTFSIPADTFITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEVMAAIFASAIHDVDHPGVSN
QFLINTNSELALMYNDVSVLENHHLAVGFKLLQEENCDIFQHLSKKQRQSLRKMAIDMDLAALGTADLGLHPVL
>gi|34810094|pdb|1Q9M|A Chain A, Three Dimensional Structures Of Pde4d In Complex With Roliprams And Implication On Inhibitor Selectivity >gi|34810095|pdb|1Q9M|B Chain B, Three Dimensional Structures Of Pde4d In Complex With Roliprams And Implication On Inhibitor Selectivity >gi|34810096|pdb|1Q9M|C Chain C, Three Dimensional Structures Of Pde4d In Complex With Roliprams And Implication On Inhibitor Selectivity >gi|34810097|pdb|1Q9M|D Chain D, Three Dimensional Structures Of Pde4d In Complex With Roliprams And Implication On Inhibitor Selectivity >gi|34811479|pdb|1OYN|A Chain A, Crystal Structure Of Pde4d2 In Complex With (R,S)-Rolipram >gi|34811480|pdb|1OYN|B Chain B, Crystal Structure Of Pde4d2 In Complex With (R,S)-Rolipram >gi|34811481|pdb|1OYN|C Chain C, Crystal Structure Of Pde4d2 In Complex With (R,S)-Rolipram >gi|34811482|pdb|1OYN|D Chain D, Crystal Structure Of Pde4d2 In Complex With (R,S)-Rolipram >gi|39654555|pdb|1PTW|A Chain A, The Crystal Structure Of Amp-bound Pde4 Suggests A Mechanism For Phosphodiesterase Catalysis >gi|39654556|pdb|1PTW|B Chain B, The Crystal Structure Of Amp-bound Pde4 Suggests A Mechanism For Phosphodiesterase Catalysis >gi|39654557|pdb|1PTW|C Chain C, The Crystal Structure Of Amp-bound Pde4 Suggests A Mechanism For Phosphodiesterase Catalysis >gi|39654558|pdb|1PTW|D Chain D, The Crystal Structure Of Amp-bound Pde4 Suggests A Mechanism For Phosphodiesterase Catalysis >gi|372467153|pdb|3V9B|A Chain A, Crystal Structure Of The Catalytic Domain Of Pde4d2 With (s)-n-(3-{1- [1-(3-cyclopropylmethoxy-4-difluoromethoxyphenyl)-2-(1-oxypyridin-4- Yl)-ethyl]-1h-pyrazl-3-yl}phenyl)acetamide >gi|372467154|pdb|3V9B|B Chain B, Crystal Structure Of The Catalytic Domain Of Pde4d2 With (s)-n-(3-{1- [1-(3-cyclopropylmethoxy-4-difluoromethoxyphenyl)-2-(1-oxypyridin-4- Yl)-ethyl]-1h-pyrazl-3-yl}phenyl)acetamide >gi|372467155|pdb|3V9B|C Chain C, Crystal Structure Of The Catalytic Domain Of Pde4d2 With (s)-n-(3-{1- [1-(3-cyclopropylmethoxy-4-difluoromethoxyphenyl)-2-(1-oxypyridin-4- Yl)-ethyl]-1h-pyrazl-3-yl}phenyl)acetamide >gi|372467156|pdb|3V9B|D Chain D, Crystal Structure Of The Catalytic Domain Of Pde4d2 With (s)-n-(3-{1- [1-(3-cyclopropylmethoxy-4-difluoromethoxyphenyl)-2-(1-oxypyridin-4- Yl)-ethyl]-1h-pyrazl-3-yl}phenyl)acetamide
IPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTL
>gi|354459613|pdb|3SL5|A Chain A, Crystal Structure Of The Catalytic Domain Of Pde4d2 Complexed With Compound 10d >gi|354459614|pdb|3SL5|B Chain B, Crystal Structure Of The Catalytic Domain Of Pde4d2 Complexed With Compound 10d >gi|354459615|pdb|3SL5|C Chain C, Crystal Structure Of The Catalytic Domain Of Pde4d2 Complexed With Compound 10d >gi|354459616|pdb|3SL5|D Chain D, Crystal Structure Of The Catalytic Domain Of Pde4d2 Complexed With Compound 10d
IPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNREWYQSTIPQSPSPAPDSPEEGRQGQTEKFELTLE
>gi|283135367|pdb|3IAD|A Chain A, Crystal Structure Of Human Phosphodiesterase 4d With Bound Allosteric Modulator >gi|283135368|pdb|3IAD|B Chain B, Crystal Structure Of Human Phosphodiesterase 4d With Bound Allosteric Modulator >gi|283135369|pdb|3IAD|C Chain C, Crystal Structure Of Human Phosphodiesterase 4d With Bound Allosteric Modulator >gi|283135370|pdb|3IAD|D Chain D, Crystal Structure Of Human Phosphodiesterase 4d With Bound Allosteric Modulator
MSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHAD
VAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAV
GFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHC
ADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDIL
DTLEDNREWYQSTIPQAPAPPLDEQNRDSQGNQVSEFISNTFLDENLYFQGHHHHHH
>gi|67464393|pdb|1ZKN|A Chain A, Structure Of Pde4d2-Ibmx >gi|67464394|pdb|1ZKN|B Chain B, Structure Of Pde4d2-Ibmx >gi|67464395|pdb|1ZKN|C Chain C, Structure Of Pde4d2-Ibmx >gi|67464396|pdb|1ZKN|D Chain D, Structure Of Pde4d2-Ibmx
IPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVA
YHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCAD
LSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDT
LEDNREWYQSTIPQ
>gi|584029024|ref|XP_006809035.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like isoform X2 [Neolamprologus brichardi]
MSTMVLGVRKRRHCEREKQHDVEILSPPPKEKEKKKRPMSQISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDID
RWGMDIFKVAEYSGNRPLTVTMYTIFQERDLLKTFDIPVDTFITFMMTLEDHYHADIAYHNSIHAADVVQSTHVLLSTPA
LEVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRDSL
RKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKER
FTQGDRERDRGMEISPMCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPSTPE
EHQAEVGPAALGAGAPIPSGGGGGDKFQFELTLEEEEEEEEEADSDLESPIENESQSAAERHRDSSSPSLSPDPRSSSGR
YRPPSPHPSRTLNLAAMSVRSPSPQRAPVSPGREGADTDRELSQEGDGVACLRLGT
>gi|58177531|pdb|1XOM|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Cilomilast >gi|58177532|pdb|1XOM|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Cilomilast >gi|58177533|pdb|1XON|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Piclamilast >gi|58177534|pdb|1XON|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Piclamilast >gi|58177535|pdb|1XOQ|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Roflumilast >gi|58177536|pdb|1XOQ|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Roflumilast >gi|58177537|pdb|1XOR|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Zardaverine >gi|58177538|pdb|1XOR|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Zardaverine >gi|61680488|pdb|1Y2B|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 3,5- Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|61680489|pdb|1Y2B|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 3,5- Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|61680490|pdb|1Y2C|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 3,5- Dimethyl-1-Phenyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|61680491|pdb|1Y2C|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 3,5- Dimethyl-1-Phenyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|61680492|pdb|1Y2D|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 1-(4- Methoxy-Phenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|61680493|pdb|1Y2D|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 1-(4- Methoxy-Phenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|61680494|pdb|1Y2E|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 1-(4- Amino-Phenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|61680495|pdb|1Y2E|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 1-(4- Amino-Phenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|61680503|pdb|1Y2K|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 3,5- Dimethyl-1-(3-Nitro-Phenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|61680504|pdb|1Y2K|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With 3,5- Dimethyl-1-(3-Nitro-Phenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester >gi|257472001|pdb|3IAK|A Chain A, Crystal Structure Of Human Phosphodiesterase 4d (Pde4d) With Papaverine. >gi|261825096|pdb|3K4S|A Chain A, The Structure Of The Catalytic Domain Of Human Pde4d With 4- (3-Butoxy-4-Methoxyphenyl)methyl-2-Imidazolidone
MGSSHHHHHHSSGLVPRGSHMTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLIT
YLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYN
DSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYS
DRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETW
ADLVHPDAQDILDTLEDNREWYQSTIPQS
>gi|178847240|pdb|2QYN|A Chain A, Crystal Structure Of Pde4d2 In Complex With Inhibitor Npv >gi|178847241|pdb|2QYN|B Chain B, Crystal Structure Of Pde4d2 In Complex With Inhibitor Npv
TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEEN
CDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
YQSTIPQS
>gi|51247619|pdb|1TB7|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Amp >gi|51247620|pdb|1TB7|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Amp >gi|51247621|pdb|1TBB|A Chain A, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Rolipram >gi|51247622|pdb|1TBB|B Chain B, Catalytic Domain Of Human Phosphodiesterase 4d In Complex With Rolipram
GSHMTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHN
NIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
PTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NREWYQSTIPQS
>gi|28948639|pdb|1MKD|A Chain A, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948640|pdb|1MKD|B Chain B, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948641|pdb|1MKD|C Chain C, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948642|pdb|1MKD|D Chain D, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948643|pdb|1MKD|E Chain E, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948644|pdb|1MKD|F Chain F, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948645|pdb|1MKD|G Chain G, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948646|pdb|1MKD|H Chain H, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948647|pdb|1MKD|I Chain I, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948648|pdb|1MKD|J Chain J, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948649|pdb|1MKD|K Chain K, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex >gi|28948650|pdb|1MKD|L Chain L, Crystal Structure Of Pde4d Catalytic Domain And Zardaverine Complex
TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEEN
CDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LQLYRQWTDRIMEEFFPQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
YQSTIPQS
>gi|159795115|pdb|2PW3|A Chain A, Structure Of The Pde4d-Camp Complex >gi|159795116|pdb|2PW3|B Chain B, Structure Of The Pde4d-Camp Complex
TEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHNVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEEN
CDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
YQSTIPQ
>gi|119394659|gb|ABL74491.1| phosphodiesterase 4D [Sus scrofa]
LSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKEL
EDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLL
STPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQ
RQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRI
MEEFFRQGDRERERGMEISPMCDK
>gi|441627991|ref|XP_004089330.1| PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Nomascus leucogenys]
MQRYKGRQTVFGASVGGGLFSAXLQHPSPRSSPLFYPSAPSGHRQLLGVGPTLSPRSTFSRFSTAGADSSSLSPPLPALG
RTREQTFLGARSRGRVLLPAIPDPFLWRMETLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDK
SAGCRERDLSPRPGLRKSRLSWPISSCRRFDLENGLSCGRRALDPQSSPGLGRVMQAPVPHSQRRESFLYRSDSDYELSP
KAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARLQCLGAAKQGPVGNPSSSNQPPPPAEDTGQKLALETLD
ELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTTEEAPQPMSRIS
GLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIMFSIFQLLLGIVGGVGGSWGSQ
SHTLTDSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETK
KVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQV
GFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEEEE
TALDKEALELPDTELLSPEAGPDPGDLPLDNQRT
>gi|347126|gb|AAA03591.1| phosphodiesterase, partial [Homo sapiens]
LAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNL
VHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQ
DLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPD
PGDLPLDNQRT
>gi|326934866|ref|XP_003213504.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like, partial [Meleagris gallopavo]
SELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSG
VLLLDNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASIEKSQVGFIDYI
VHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEESKQGQTEKFQFELTLEEDGESDTEKDSGSQVEE
DTSCSDSKTLCTQDSESTEIPLDEQVGEEVEEEENQTEACVVDHSSDM
>gi|47220046|emb|CAG12194.1| unnamed protein product [Tetraodon nigroviridis]
MTWTTQECLNQFLINTNSELALMYNDESVLENHHLAVGFKLLHEDNCDIFQNLSKRQRQSLRKLVLATDMSKHMSLLADL
KTMVETKKVTSSGVLLLDHYTDRIQVLRNLVHCADLSNPTKPLAVYRQWTERIMEEFFRQGDKERERGMEISPMCDKHTA
SVEKSQVGFIDYIVHPLWETWGDLVHPDAQEILDTLEDNRDWYQSTIPQSPSPPPVGQDKELNACMDKFQFELTLDDGSE
R
>gi|543750460|ref|XP_005515927.1| PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like, partial [Columba livia]
PSRSGNQVSEYISSTFLDKQQEVEIPPAKDKDKEKERRKRPMSQISGVRKLPHGSSLAAAAIPRFGVRTDQEGLLAKELE
DTNKWGLNVFKVAEYSGNRPLTVIMYSIFQERDLMKTFRIPVDTFITYMLTLEDHYHADVAYHNSIHAADVAQSTHVLLS
TPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQ
